Clinical trials: Prognostic Factors
Silent Cerebral Infarct, Biomarkers / Blood
Biomarkers as Prognostic Factors of Silent, Cerebral Infarctions in Patients Undergoing High-thromboembolic-risk Transcatheter Interventions
Background: The transcatheter interventions with high thromboembolic risk, as transcatheter carotid angioplasty or transcatheter ablation of cardiac arrhythmias are associated with asymptomatic strokes- silent strokes.
- Conditions
- Silent Cerebral Infarct, Biomarkers / Blood, Cardiac Ablation, Cognitive Impairment
- Trial name
- PRINCESS (NCT07844850)
- Testing
- High-thromboembolic-risk transcatheter interventions
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Pituitary Adenoma, Pituitary Cancer
A Twenty-years' Experience in Pituitary Disease.
Pituitary tumors represent a heterogeneous group of neoplasms by histotype. The pituitary adenomas are the most frequent heteroformation, among those affecting the pituitary gland, followed by meningiomas, craniopharyngiomas…
- Conditions
- Pituitary Adenoma, Pituitary Cancer, Pituitary Disease
- Trial name
- TYEPDD (NCT06973824)
- Testing
- Frequency of disease recurrence
- Where
- Italy
- Volunteers
- 1,600 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Meibomian Gland Dysfunction
Effects and Prognostic Factors of Intensive Pulse Light Treatment for Meibomian Gland Dysfunction
The investigators are going to Investigate the comparative efficacy of intense pulsed light therapy alone with that of intense pulsed light plus meibomian gland expression for meibomian gland dysfunction.
- Trial name
- NCT03950115
- Testing
- Intense Pulsed Light (IPL)
- Where
- South Korea
- Volunteers
- 81 people
- Sponsor
- Samsung Medical Center
Intracerebral Hemorrhage
Etiology and Prognostic Risk Factors of Intracerebral Hemorrhage in Beijing
There were lack of data and analysis about medical management, etiology, and long-term outcome of Intracerebral Hemorrhage (ICH) in Beijing.
- Trial name
- NCT02350010
- Testing
- CT Angiography
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Beijing Neurosurgical Institute
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Study of Electrical Prognostic Factors of Response to Intravenous Immunoglobulin Treatment in Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Chronic inflammatory demyelinating polyradiculoneuropathy (PIDC) is an acquired dysimmune polyneuropathy whose prevalence is estimated to be between 1 to 4 per 100,000 depending on the study, with an incidence of less than 1 per…
- Trial name
- PRONELEC PIDC (NCT03967899)
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Hepatitis B, Acute-On-Chronic Liver Failure
Long-term Prognosis of Patients With Hepatitis B Related Acute-on-chronic Liver Failure
This study is to investigate the long-term outcomes and prognostic risk factors in patients recovered from hepatitis B virus related acute on-chronic liver failure.
- Trial name
- NCT04310787
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
SARS-CoV-2, Outcome, Fatal
Prognostic Factors of Patients With COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China has been declared a public health emergency of international concern.
- Trial name
- NCT04292964
- Where
- China
- Volunteers
- 201 people
- Sponsor
- Chongqing Medical University
Emergency Surgery
Is TIme From adMission to surgEry an Independent Prognostic Factor for Survival of Patients With Gastro-intestinal Perforation Associated With Septic Shock: (TIME) An Italian Intersocietary Retrospective and Prospective Observational Trial
Gastro-intestinal perforation is a condition that can become life-threatening in case of appearance of systemic symptoms, sepsis-related peripheral hypoperfusion and single or multiple organ failure needing a prompt intervention…
- Trial name
- TIME (NCT04811755)
- Testing
- Surgical timing from ED admission to surgery
- Volunteers
- 3,276 people
- Sponsor
- San Luigi Gonzaga Hospital
Lung Cancer - Non Small Cell
Integrating Machine Learning for Prognostic Prediction in Stage I NSCLC by CT Images and Pathological Factors
The investigators retrospectively collected the participants with stage I non-small cell lung cancer (NSCLC) patients resected between January 2010 to December 2020 for training and internal validation.
- Trial name
- Stage I NSCLC (NCT06737367)
- Testing
- CT radiomic analysis
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Jinling Hospital, China
Neuroendocrine Neoplasm
Definition of a Multiparametric Prognostic and Predictive System of Classification of NET G3 Patients
The 2017 World Health Organization (WHO) introduced a new category of high-grade, well-differentiated neuroendocrine neoplasms (NENs) that called neuroendocrine tumors (NETs) G3 in pancreatic NENs classification and, then, in…
- Trial name
- TAPIOCA (NCT06343428)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- European Institute of Oncology
Immune Thrombocytopenia, Pregnancy
Immune Thrombocytopenia in Pregnancy
The pregnancy may activate flares of certain autoimmune diseases such as lupus. The influence of pregnancy on the evolution of ITP was never studied while this pathology affects firstly women old enough to procreate.
- Trial name
- TIGRO (NCT02892630)
- Testing
- No intervention
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Invasiveness, Neoplasm
KLHL14 Expression as Predicting Factor of Invasiveness in pitNET
OBJECTIVE: The objective of this study is to evaluate the correlation between KLHL14 expression and its cytoplasm-nuclear localisation and pituitary adenomas biological behaviour with particular focus on its role in epithelial…
- Trial name
- NCT06247709
- Testing
- Immunohistochemical expression in pitNET cells of KLHL14
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Federico II University
Diffuse Large B-cell Lymphoma
Prognostic Value of Clinical and Biological Factors in Patients With Refractory/Relapsed Diffuse Large B-cell Lymphoma
The purpose of this study is to evaluate the prognostic value of clinical and biological factors in patients with refractory/relapsed Diffuse Large B-Cell Lymphoma.
- Trial name
- PRO-R-IPI (NCT01369784)
- Where
- 56 sites in Spain
- Volunteers
- 158 people
- Sponsor
- Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea
Atrial Fibrillation
Inflammatory Response as a Prognostic Factor of Recurrence of Atrial Fibrillation After Ablation
The aim of this study is to evaluate inflammatory response as a prognostic factor of atrial fibrillation recurrency after ablation.
- Trial name
- ACtIVE-AF (NCT02844959)
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Warsaw
Carcinoma of Head/Neck
Observational Study on Thyroid Tumors and EvaLuation of the roLe of New pOntential Predictive/Prognostic Factors
The OTELLO Study is a monocentric, ambispective observational study that systematically analyzes the clinical, laboratory, anatomopathological, and molecular characteristics of patients with thyroid neoplasms treated at the…
- Trial name
- OTELLO (NCT07064369)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Salivary Gland Cancer, Salivary Gland Neoplasms
Survival With Patients Treated With Salivary Gland Cancer
Salivary gland malignancies is very heterogenous group of tumors regarding tumor histology and localization. The aim of this study is to assess main clinical and pathological parameters related to patients survival
- Trial name
- NCT05390294
- Testing
- Surgical intervention with or without postoperative adjuvant therapy
- Where
- Serbia
- Volunteers
- 250 people
- Sponsor
- Clinical Center of Vojvodina
To Investigate the Characteristics and Prognostic Factors of T. Marneffei Infections and the Causes of Misdiagnosis, To Study the Recurrence Indicators and Establish a Therapeutic Effect Evaluation System of T. Marneffei Infections
Retrospective Analysis of the Epidemiological Change and Determinants of Prognosis of Talaromycosisof Human Immunodeficiency Virus Negative Host in Guangxi
Through a multi-center large-sample retrospective study, the epidemiological changes of TSM in Guangxi have been reviewed, its incidence trend was understood to attract the attention of clinicians; the multiple programs of…
- Trial name
- RAECDPT (NCT03819348)
- Testing
- the multiple programs of antifungal therapy for HIV-negative host
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Guangxi Medical University
Hip Osteoarthritis, Total Hip Arthroplasty
Clinical Phenotypes in Persons With Hip Osteoarthritis and Prognostic Factors for Outcome After Total Hip Arthroplasty
This prospective longitudinal cohort study aims (1) to identify clinical phenotypes in persons with hip osteoarthritis and after total hip arthroplasty, and (2) to identify prognostic factors for outcomes after total hip…
- Trial name
- HIPPROCLIPS (NCT05265858)
- Testing
- Total Hip Arthroplasty
- Where
- 2 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Hasselt University
Coronary Artery Disease
Influencing Factors and Outcomes of DCB Angioplasty
This ambiprospective observational study evaluates the long-term safety and efficacy of Paclitaxel Drug-Coated Balloon (DCB) angioplasty in approximately 20,000 patients withcoronary artery lesions in large vessels.
- Trial name
- FWHZ-DCB (NCT06620458)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Ovarian Cancer
Validation of KELIM as a Predictive/Prognostic Factor for Maintenance Treatment With iPARP in First-Line Ovarian Cancer
This study aims to understand whether it is possible to predict the effectiveness of maintenance treatment with PARP inhibitors following first-line chemotherapy in ovarian cancer, and thus better target the patients who benefit…
- Trial name
- KELI-PAOLA (NCT06660147)
- Where
- 24 sites in France, Monaco
- Volunteers
- 243 people
- Sponsor
- ARCAGY/ GINECO GROUP