Clinical trials: Program Implementation
Lymphedema, Recurrent Breast Cancer
Sentinel and/or Axillary Lymph Node Biopsy With or Without Axillary Reverse Mapping in Reducing Incidence and Severity of Arm Lymphedema in Stage 0-2 Patients.
Lymph node biopsy followed by axillary reverse mapping may reduce the incidence and severity of arm lymphedema. This randomized phase II trial is studying how well sentinel and/or axillary lymph node biopsy with or without…
- Conditions
- Lymphedema, Recurrent Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer
- Trial name
- NCT01276054
- Testing
- technetium Tc 99m sulfur colloid, methylene blue, indocyanine green solution
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Southern California
Suicide
REACH VET Implementation Program Evaluation
The VA's Office of Mental Health and Suicide Prevention implemented an new program to increase suicide prevention outreach for Veterans at highest risk for suicide.
- Trial name
- REACH VET (NCT03280225)
- Testing
- External facilitation
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Implementation Research, Tobacco Cessation
Comparing Smartphone to In-person Training to Scale up a Tobacco Control Program for Teachers in India
This study aims to compare the implementation and effectiveness of the Tobacco-Free Teachers, Tobacco-Free Society (TFT-TFS) program when delivered through in-person training versus a smartphone-based training model.
- Trial name
- NCT05500235
- Testing
- Smart phone based training, In person training
- Where
- India
- Volunteers
- 2,718 people
- Sponsor
- Harvard School of Public Health (HSPH)
Asthma
CARE FOR ALL：an Evaluation of an Asthma QIP
This is an evaluation on an asthma Quality Improvement Program (QIP, including GINA guideline education/training and implementation) to understand the change of physician behaviours, which leads to the change of patient outcomes.
- Trial name
- CARE FOR ALL (NCT05440097)
- Testing
- QIP intervention
- Where
- 32 sites in China
- Volunteers
- 1,500 people
- Sponsor
- AstraZeneca
Overweight and Obesity
Adapting an Evidenced-based Weight Management Intervention and Testing Strategies to Increase Implementation in Community Mental Health Programs
This is a pilot randomized clinical trial testing an implementation intervention to support delivery of a behavioral weight loss program at community mental health programs.
- Trial name
- ACHIEVE-D (NCT03454997)
- Testing
- training including in-person and online, organizational strategy meetings, performance coaching
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Physical Activity
Developing and Testing an Implementation Strategy for Active Learning to Promote Physical Activity in Children
The purpose of this study is to develop an implementation strategy to improve the use and sustainment of active learning in elementary schools and to conduct a feasibility study to evaluate the impact of the developed…
- Trial name
- NCT05048433
- Testing
- Implementation strategy for active learning to promote physical activity, Usual implementation support
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Asthma
US PRECISION Implementation Study
The primary objective of this community program intervention study is to assess the process and potential benefits of integrating the AIRQ®, Asthma Checklist, and educational resources (PRECISION program) into clinical practice…
- Trial name
- NCT04891978
- Testing
- AIRQ, Asthma Checklist, PRECISION Program (Educational Resources)
- Where
- 13 sites in United States
- Volunteers
- 857 people
- Sponsor
- AstraZeneca
Obesity
Healthy Eating and Active Living Taught at Home (HEALTH) Dissemination & Implementation (D&I)
This project evaluates the effectiveness of an evidence-based intervention (HEALTH) to prevent weight gain and promote weight loss when disseminated and implemented in real-world settings, through Parents as Teachers.
- Trial name
- HEALTH D&I (NCT03758638)
- Testing
- Healthy Eating & Active Living Taught at Home, Usual Care
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Delirium
Implementation Outcome Assessments of the Emergency Department Delirium Screening and Detection Program
Delirium occurs in up to 20% of older adults presenting to the Emergency Department (ED) and is associated with poor outcomes. Failure to identify patients with ED delirium not only prevents initiation of mitigation strategies…
- Trial name
- ED-DDP (NCT05606328)
- Testing
- Emergency Department Delirium Screening and Detection Program (ED-DDP)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Obesity
Evaluation of an Enhanced Delivery Model for Go NAPSACC
This study will compare the effectiveness and cost of Basic and Enhanced delivery models for Go NAPSACC on child care centers' use of evidence-based nutrition and physical activity practices.
- Trial name
- NCT03938103
- Testing
- Enhanced Go NAPSACC, Basic Go NAPSACC
- Where
- 2 sites in United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cervical Cancer, Uterine Endometrial Cancer
Implementation of a Rapid Recovery Program in Gynecologic Oncology Surgery: A Pilot Study
Over 600,000 hysterectomies are performed annually in the United States. Despite increasing use of less invasive approaches, the majority of hysterectomies are still performed via traditional laparotomy, which can be associated…
- Conditions
- Cervical Cancer, Uterine Endometrial Cancer, Ovarian Cancer
- Trial name
- NCT01705288
- Testing
- Laparotomy, intravenous narcotics, standard anesthesia
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Preconception Care
Nthabi in Lesotho - Implementation
This project will determine how well the mobile health (mHealth) Nthabi application is introduced and used at district hospitals in Lesotho.
- Trial name
- NCT04354168
- Testing
- mHealth Application
- Where
- Lesotho
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Boston University
Substance Abuse
Family Listening Program: Multi-Tribal Implementation and Evaluation
This is a five-year R01 effectiveness trial where tribal partners are committed to assessing the Family Listening/Circle Program's effectiveness and disseminating the approach and intervention within Indian Country as a best…
- Trial name
- NCT03142009
- Testing
- Intergenerational culturally adapted curriculum
- Where
- 3 sites in United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Dementia
Implementation of MIND at Home Into Primary Care for People Living With Dementia
The number of people living with dementia (PLWD) is growing. PLWD are often cared for at home by an informal caregiver, but this care is often not sufficient, resulting in costly hospitalizations and other unnecessary and…
- Trial name
- NCT05406921
- Testing
- MIND at Home
- Where
- 2 sites in United States
- Volunteers
- 410 people
- Sponsor
- American Medical Group Association
Proton Pump Inhibitors
Evaluation of the National Randomized Proton Pump Inhibitor De-prescribing (RaPPID) Program
Proton pump inhibitors (PPIs) are medications used to treat acid-related stomach disorders, such as chronic heartburn. These medications are widely used by Veterans, with over 11 million 30-day prescriptions being filled each…
- Trial name
- RaPPID (NCT03719170)
- Testing
- PPI De-prescribing Program
- Where
- 4 sites in United States
- Volunteers
- 220,306 people
- Sponsor
- VA Office of Research and Development
Cirrhosis, Liver
Improving Pain Management and Opioid Safety for Patients With Cirrhosis
This project aims to test a behavioral intervention in patients with liver cirrhosis and chronic pain and teach self pain-management skills.
- Trial name
- NCT05128578
- Testing
- Liver Education About Pain (LEAP), Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
HIV/AIDS
Biomedical HIV/AIDS Prevention Program Yunnan
B-HAPPY is an implementation project to study the process by which pre-exposure prophylaxis (PrEP) is introduced and integrated into a specific international health system facing high rates of HIV incidence among men who have sex…
- Trial name
- B-HAPPY (NCT03992274)
- Testing
- Enhanced implementation of PrEP
- Where
- China
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Columbia University
Smoking Cessation
Implementation of Smoking Cessation Within NCI Community Oncology Research Program (NCORP) Sites
Evaluate a multi-faceted training program to improve short-term smoking cessation rates (<14 days post-visit) and short (3 months) and sustained abstinence (6 months) among 1,114 enrolled smokers who present for low-dose computed…
- Trial name
- OaSiS (NCT03291587)
- Testing
- Personnel Training and Coaching Calls
- Where
- 49 sites in United States
- Volunteers
- 1,094 people
- Sponsor
- Wake Forest University Health Sciences
Colorectal Cancer
Scaling CRC Screening Through Outreach, Referral, and Engagement (SCORE)
This study will test the effectiveness of mailing fecal immunochemical tests (FITs) in increasing colorectal cancer (CRC) screening rates in U.S. adults ages 45-75.
- Trial name
- SCORE (NCT04406714)
- Testing
- Trial Mailed FIT Intervention - Age Group 50-75, Sub-Study Mailed FIT Intervention Enhanced Envelope - Age Group 45-49, Sub-Study Mailed FIT Active Comparator Plain Envelope - Age Group 45-49
- Where
- 2 sites in United States
- Volunteers
- 4,318 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Trauma/Injury Problem
Pre and Post-Implementation of Injury/Trauma First Aid Training Among Early Secondary School Students in Fako, Cameroon
To save lives, alleviate pain, and prevent injuries from worsening before medical assistance can be summoned, first aid is essential. These fundamental skills are accessible to everyone, including young people.
- Trial name
- NCT07110077
- Testing
- Young First Aiders Traing of Early Secondry School children
- Where
- Cameroon
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Buea