Clinical trials: Prolactin
Hyperprolactinemia, Insulin Resistance
Substrate Metabolism and Insulin Sensitivity in Patients With Hyperprolactinemia Before and After Treatment
The purpose of this study is to investigate the effects of chronic elevated levels of Prolactin on metabolism and insulin sensitivity by studying patients with hyperprolactinemia before and after treatment.
- Trial name
- NCT00699530
- Testing
- Cabergoline
- Where
- Denmark
- Sponsor
- University of Aarhus
Lactation
Recombinant Human Prolactin for Lactation Induction
The purpose of the study is to assess the safety and determine the effects of the hormone prolactin on lactation (breast milk production).
- Trial name
- NCT00181649
- Testing
- Recombinant human prolactin
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Macroprolactinoma
Efficacy of Rapid Escalation of Cabergoline in Comparison to Conventional Dosing in Prolactin Secreting Macroadenomas.
To study the effects of rapid escalation of Cabergoline in comparison to conventional dosing in macroprolactinomas. Rapid escalation of cabergoline may help in earlier normalization of prolactin and shrinkage of tumor mass, and…
- Trial name
- NCT01143584
- Testing
- Cabergoline
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Does Postpartum Massage Affect Leptin, Prolactin and Growth Hormone
Ameliorative Potential of Relaxing Back Massage on Puerperial Women's Hormones and Infant Weight
Effect of massage on hormone levels in puerperal women
- Trial name
- NCT06311643
- Testing
- Postpartum back massage in study group
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Prolactinoma, Prolactin-Producing Pituitary Tumor
Validation of a Quality of Life Metric "Prolac-10"
This is a short-term validation study of a quality of life metric "Prolac-10" for patients diagnosed with a prolactinoma, undergoing new medical therapy.
- Conditions
- Prolactinoma, Prolactin-Producing Pituitary Tumor, Pituitary Tumor, Prolactinoma Macroadenoma
- Trial name
- Prolac-10 (NCT04106531)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Ohio State University
Monoamine Oxidase Inhibitor Activity, Prolactin Levels
Pharmacodynamic Profile of 'Blackadder' Blackcurrant Juice Effects Upon the Monoamine Axis in Humans
The current study uses a double-blind, placebo-controlled, randomised cross- over design to assess the pharmacodynamics of the platelet MAO-B inhibition, plasma prolactin levels and blood glucose levels after consumption of a…
- Conditions
- Monoamine Oxidase Inhibitor Activity, Prolactin Levels, Postprandial Blood Glucose
- Trial name
- NCT02962752
- Testing
- Blackadder Juice
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Schizophrenia, Bipolar Disorder
A Study to Evaluate the Safety and the Effects of Risperidone Compared With Other Atypical Antipsychotic Drugs on the Growth and Sexual Maturation in Children
The purpose of this study is to evaluate the effects of risperidone compared with other atypical antipsychotic drugs on the physical maturity, growth and development of children, and the risk of prolactin-related adverse events…
- Conditions
- Schizophrenia, Bipolar Disorder, Autistic Disorder, Conduct and Other Disruptive Behavior Disorders
- Trial name
- NCT01050582
- Testing
- Risperidone, Other atypical antipsychotic drugs
- Where
- 28 sites in United States, Belgium and 4 more
- Volunteers
- 244 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
PCOS (Polycystic Ovary Syndrome)
LH/FSH, Testosterone, Prolactin, and Ferritin in PCOS Patients in Jordan
Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder impacting women of reproductive age. Characterized by chronic anovulation, hyperandrogenism, and the presence of multiple small ovarian cysts.
- Trial name
- PCOS patients (NCT07112768)
- Testing
- Serum levels of LH, FSH, testosterone, prolactin, and ferritin
- Where
- Jordan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Infertility
Variation in Serum Prolactin Levels During IntraCytoplasmic Sperm Injection
The purpose of the study is to determine whether or not stressful conditions such as ovum pick and awaiting Embryo Transfer is associated with significant increase in serum Prolactin (PRL) concentration in some…
- Trial name
- NCT02292953
- Testing
- Serum Prolactin levels
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Post Operative Pain, Erector Spinae Plane Block
The Effect of Local Anesthetic Infiltration or Erector Spina Plan Block on Stress Hormone Response
Laparoscopic cholecystectomy is one of the most common operations in abdominal surgery. Effective analgesia in the postoperative period; It is of great importance in terms of acceleration of recovery, prevention of atelectasis…
- Conditions
- Post Operative Pain, Erector Spinae Plane Block, Inguinal Hernia
- Trial name
- NCT05717530
- Testing
- wound site local anesthesic infiltration, Erector spina plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Dopamine Receptor Occupancy, Medication Satisfaction
Validation of Receptor Occupancy Simulation
To estimate dopamine receptor occupancy by aripiprazole using computer simulation To measure dopamine receptor occupancy by aripiprazole in patients treated with the antipsychotics To validate the simulation result by comparing…
- Conditions
- Dopamine Receptor Occupancy, Medication Satisfaction, Prolactin Level, Schizophrenia
- Trial name
- NCT01660880
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Seoul National University Hospital
Prolactinoma
Metabolic Outcomes in Patients With Prolactinomas Under Dopamine Agonist Treatment
This randomized, active-controlled, parallel-arm, single-blind trial is to compare the effects of Dopamine agonists (DA) therapy targeting different established treatment strategies on glucose metabolism assessed by an oral…
- Trial name
- ProBOLIC (NCT07045935)
- Testing
- Cabergoline (Dopamine Agonist)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Poly Cystic Ovary Syndrome
Therapeutic Role of Flax Seed for Poly Cystic Ovary Syndrome
The study was conducted to determine the therapeutic role of flax seed for Poly cystic ovary syndrome. A sample of 100 subjects were collected. The subjects were from various age group ranging from 18 to 45 years.
- Trial name
- NCT03713138
- Testing
- flaxseed powder
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Allied Hospital Faisalabad
Scizophrenia
Carbergoline for Antipsychotic Induced Hyperprolactinemia.
The goal of this clinical trial is to learn if cabergoline is safe to use in patients with antipsychotic-induced hyperprolactinemia in adults with scizophrenia.
- Trial name
- NCT07386080
- Testing
- Cabergoline (Dopamine Agonist)
- Where
- Denmark
- Volunteers
- 146 people
- Sponsor
- Zealand University Hospital