Clinical trials: Prolapse Uterus
Anesthesia, Local, Prolapse
Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy
The purpose of this study is to assess whether the transversus abdominis plane block (Tap block) is different than the oral postoperative pain medications in controlling pain after robotic sacrocolpopexy.
- Conditions
- Anesthesia, Local, Prolapse, Prolapse; Female, Prolapse, Vaginal
- Trial name
- SACROTAP (NCT04440475)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- ProMedica Health System
Prolapse, Vaginal, Stress Urinary Incontinence
Perineal Massage for Pessary Examinations
Pessaries are effective non-surgical devices for reduction of prolapse. However, use of pessaries are limited in some women due to patient discomfort.
- Conditions
- Prolapse, Vaginal, Stress Urinary Incontinence, Pessaries, Pain
- Trial name
- NCT06416982
- Testing
- Perineal massage
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of North Carolina, Chapel Hill
Uterine Prolapse
Abdominal Versus Vaginal Hysteropexy
This study will compare the vaginal versus the abdominal approach for the management of uterine prolapse
- Trial name
- NCT03494582
- Testing
- Sacral Hysteropexy, sacrospinous Hysteropexy
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Ain Shams Maternity Hospital
Pelvic Organ Prolapse (POP), Genital Prolapse
Safety and Performance of a Pelvic Floor Mesh Implant (LatGYNious)
The purpose of the clinical investigation is to verify that the investigational device (LatGYNious) is appropriate to significantly improve the pelvic organ prolapse in patients.
- Conditions
- Pelvic Organ Prolapse (POP), Genital Prolapse, Uterus Prolapse, Laparoscopic Surgery
- Trial name
- NCT07066761
- Testing
- Laparoscopic lateral suspension with surgical mesh (LatGYNious)
- Where
- 5 sites in Austria, Germany
- Volunteers
- 85 people
- Sponsor
- A.M.I. Agency for Medical Innovations GmbH
Cystocele, Uterine Prolapse
Outcomes of Anterior Colporrhaphy Versus Graft Reinforced Anterior Prolapse Repair
The purpose of this study is determine whether grafted anterior vaginal prolapse repair is more effective and associated with less complications than prolapse repair with suture.
- Conditions
- Cystocele, Uterine Prolapse, Urinary Incontinence
- Trial name
- NCT00535301
- Testing
- grafted anterior prolapse repair, sutured anterior vaginal prolapse repair
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pelvic Organ Prolapse
Comparison of Mesh-Based and Mesh-Free Laparoscopic Pectopexy in Uterus-Preserving Surgery for Apical Prolapse
This retrospective cohort study compares anatomical and functional outcomes of mesh-based and mesh-free laparoscopic uterus-preserving pectopexy in women with apical pelvic organ prolapse.
- Trial name
- PectoMesh (NCT07080957)
- Testing
- Mesh-free laparoscopic uterus-preserving pectopexy, Mesh-based laparoscopic uterus-preserving pectopexy
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Havva Betül Bacak
Pelvic Organ Prolapse, Prolapse Uterus
Combination of Laparoskopic Uterosacral Ligament and Round Ligament Plication, A Meshless Method in the Surgical Treatment of Pelvic Organ Prolapse.
Postoperative Results of a Meshless Method in the Surgical Treatment of Pelvic Organ Prolapse; Combination of Laparoscopic Uterosacral Ligament and Round Ligament Plication.
- Conditions
- Pelvic Organ Prolapse, Prolapse Uterus, Prolapse Bladder
- Trial name
- NCT04894032
- Testing
- Combination of Laparoscopic Uterosacral Ligament and Round Ligament Plication.
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Pelvic Organ Prolapse, Laparoscopy
Comparison of Laparoscopic Sacrohysteropexy, Modified Laparoscopic Lateral Suspension and Laparoscopic Pectopexy.
The aim of this study was to compare the results of laparoscopic sacrohysteropexy, laparoscopic modified lateral suspens9ion and laparoscopic pectopexy between January 2017 and December 2019 in our clinic.(Patients with at least…
- Trial name
- NCT04178083
- Testing
- medical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Diyarbakir Women's and Children's Diseases Hospital
Uterine Prolapse Without Vaginal Wall Prolapse
The NeuGuide™ System for Vaginal Colpopexy in the Treatment of Uterine Prolapse
The objective of the study is to assess the long term safety, durability of clinical effectiveness and cost effectiveness of the NeuGuide™ system when used for vaginal colpopexy in the treatment of uterine prolapse.
- Trial name
- NCT03436979
- Testing
- NeuGuide™ System
- Where
- 15 sites in United States, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Pop Medical Solutions
Pelvic Organ Prolapse, Gynecologic Cancers
Electronic Catheter Stethoscope
This is an observational, exploratory study designed to collect (record) and analyze normal and abnormal sound data from the human bladder during surgery using a novel sensor-based catheter system (Electronic Catheter…
- Conditions
- Pelvic Organ Prolapse, Gynecologic Cancers, Uterine Leiomyomata, Adenomyosis
- Trial name
- NCT01463462
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of South Florida
Uterine Prolapse, Urine Incontinence
The Assessment of Fibrin Clot Phenotype and Thrombin Generation in Women After Urogynecological Surgeries.
Determination of fibrin clot properties along with thrombin generation in women after urigynecological surgery.
- Trial name
- NCT07295782
- Testing
- determination of fibrin clot properties
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Pelvic Organ Prolapse (POP)
Restorelle Direct Fix Anterior and Posterior (A&P) for Female Pelvic Organ Prolapse: A Prospective Post Market Study
This is a prospective, multi-center study designed to assess the palpability of the Restorelle Direct Fix A\&P mesh after vaginal reconstruction surgery.
- Trial name
- (A&P) (NCT01378065)
- Testing
- Restorelle Direct Fix A&P
- Where
- 6 sites in United States
- Volunteers
- 31 people
- Sponsor
- Coloplast A/S
Urinary Incontinence, Stress, Uterine Prolapse
Colpopexy and Urinary Reduction Efforts (CARE) Protocol
Pelvic organ prolapse occurs when the muscles holding pelvic organs (e.g., the uterus or bladder) weaken and the organs fall or slide down into the vagina. Pelvic organ prolapse can be corrected with surgery.
- Conditions
- Urinary Incontinence, Stress, Uterine Prolapse, Vaginal Prolapse
- Trial name
- CARE (NCT00065845)
- Testing
- Burch urethropexy at time of sacrocolpopexy
- Where
- 7 sites in United States
- Volunteers
- 322 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pelvic Organ Prolapse
Comparison of Laparoscopic Pectopexy and Laparoscopic Lateral Suspension Techniques in Uterine-preserving Apical Prolapsus Repair
The aim of the study will be to compare the laparoscopic pectopexy (LP) and laparoscopic lateral suspension (LLS) techniques in the management of uterine sparing apical prolapse (POP-Q >2) at 1 year and yearly up to 2 years.
- Trial name
- NCT05143658
- Testing
- LLS versus LP
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pelvic Organ Prolapse
Flat Polypropylene Mesh in the Treatment of Uterine and Recurrent or Advanced Pelvic Organ Prolapse
This study is being done to evaluate the safety and feasibility of using flat polypropylene Restorelle® mesh, an ultra-lightweight mesh, for transvaginal use in surgically correcting certain specific cases of pelvic organ…
- Trial name
- NCT06225375
- Testing
- Restorelle® Flat Mesh
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Michigan Institution of Women's Health PC
Use of Pessary Reduce the Number of Prolapse Recurrence, Uterine Prolapse
The Effect of Pessary Post Vaginal Prolapse Repair, for One Month, to Reduce the Recurrence Rate of Prolapse
Genital prolapse is a common complain. 30-40% of women will complain of uterine prolapse or cystocele or rectocele, or mixed. About half of them will require surgical repair for the prolapse, with or without hysterectomy.
- Conditions
- Use of Pessary Reduce the Number of Prolapse Recurrence, Uterine Prolapse, Cystocele, Rectocele
- Trial name
- pfgp (NCT03056586)
- Testing
- vaginal pessary
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Vaginal Prolapse
Using a Sheathed Speculum to Visualize and Access the Cervix In Women With Excessive Vaginal Tissue
The main objective of the study is to assess the effectiveness of the sheathed speculum in providing adequate visualization and access to the cervix in patients with excessive vaginal tissue.
- Trial name
- NCT01409902
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Leiomyoma, Pelvic Organ Prolapse
The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures
This study evaluates the influence of the transversus abdominis plane block on the intensity of postoperative pain and the concentration of proinflammatory and pain factors after hysterectomy by laparotomy.
- Conditions
- Leiomyoma, Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Chronic Pain
- Trial name
- TAP (NCT04172272)
- Testing
- Systemic multimodal analgesia administered intravenously, Transversus abdominis plane block (TAP block), Combined transversus abdominis plane block (TAP block) with systemic multimodal analgesia administered intravenously
- Where
- 2 sites in Croatia
- Volunteers
- 75 people
- Sponsor
- General Hospital Pula
Vaginal Prolapse
Posterior IVS Versus Sacrospinous Suspension in Vaginal Vault Prolapse Repair
Hypothesis / aims of study The aim of this multicentre study is to evaluate anatomical and functional results of an innovative posterior tape in vaginal prolapse repair by vaginal route, in comparison to the sacrospinous…
- Trial name
- NCT00153231
- Testing
- IVS, Sacrospinofixation
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Constipation, Prolapse, Vaginal
Effect of Preoperative Fiber on Postoperative Bowel Function
Post-operative constipation is one of the most common complaints after pelvic organ prolapse surgery. Psyillum fiber is an FDA-approved, over the counter dietary supplement that is commonly used to treat constipation.
- Trial name
- NCT04882995
- Testing
- Psyillium fiber
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester