Clinical trials: Prolapsed Intervertebral Disc
Lumbar Disc Herniation, Postoperative Pain
Comparison of the Effects of Quadratus Lumborum Block and Retrolaminar Block on Postoperative Pain in Lumbar Disc Herniation Surgery
This study aims to compare the analgesic efficacy of quadratus lumborum block (QLB) and retrolaminar block (RLB) in patients undergoing lumbar disc herniation surgery.
- Trial name
- NCT07166250
- Testing
- Quadratus Lumborum Block, Retrolaminar Block
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kocaeli University
Herniated Disc
Nucleoplasty for Contained Herniated Lumbar Discs
This is a prospective randomised double blind comparison trial. Fifty patients will be included, 25 in the nucleoplasty treatment group, 25 in the control group. The nucleoplasty group will undergo the nucleoplasty treatment.
- Trial name
- NCT00124774
- Testing
- Nucleoplasty
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Rijnstate Hospital
Herniated Disk, Temporomandibular Disorders
Randomized Clinical Trial of Treatment for Temporomandibular Joint (TMJ) Disc Displacement
The effectiveness of physical therapy for treatment of anterior disc displacement without reduction of temporomandibular disorders has not been well defined.
- Trial name
- NCT00936338
- Testing
- splint and joint mobilization self exercise
- Where
- Japan
- Volunteers
- 44 people
- Sponsor
- Tokyo Medical and Dental University
Lumbar Disc Herniation, Lumbar Disc Surgery
Effectiveness of Virtual Reality-Assisted Physical Therapy in the Acute Phase After Lumbar Disc Surgery
The goal of this clinical trial is to evaluate the effectiveness of virtual reality-assisted physical therapy in the acute postoperative period after lumbar disc surgery.
- Trial name
- NCT07204197
- Testing
- Virtual Reality-Assisted Physical Therapy, Conventional Physical Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Hacettepe University
Lumbar Disc Herniation, Degenerative Spinal Stenosis
CETIS-I (CEra Traction Improves Spine-I)
In this clinical trial, equivalence is evaluated by exploratory comparison of changes in X-Ray lesions with test group (Cerazem Master V6) and control group (physical therapy) in patients with intervertebral disc herniation and…
- Conditions
- Lumbar Disc Herniation, Degenerative Spinal Stenosis, Spine Traction
- Trial name
- NCT05549596
- Testing
- Ceragem Master V6 Traction, Physical therapy with standard traction device
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Ceragem Clinical Inc.
Pain, Disability
Do Benzodiazepines Improve the Outcome of Mechanical Physiotherapy for Lumbar Disk Prolapse
Sixty patients were randomized to receive either placebo or diazepam in addition to mechanical physiotherapy and analgesics for the first 7 days of conservative treatment of clinically and radiologically confirmed lumbar disk…
- Conditions
- Pain, Disability, Paresis
- Trial name
- NCT00533286
- Testing
- benzodiacepine
- Sponsor
- University Hospital Tuebingen
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Herniated Disc, Sciatica
Intradiscal Discogel® in Resistant Sciatica
Sciatica due to herniated disc is a major cause of disability in young adults. Surgery is the gold-standard and the only controlled treatment in case of failure of conservative treatment.
- Conditions
- Herniated Disc, Sciatica, Persistent Pain, Leg
- Trial name
- EDIS (NCT02313350)
- Testing
- Chemonucleolysis with Discogel, open discectomy
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Scarring, Spinal Stenosis
dHACM in Lumbar Decompression and Microdiscectomy Surgery
Prospective evaluation of the safety and efficacy of dHACM on clinical outcomes in lumbar laminectomy and microdiscectomy patients as assessed by Oswestry Disability Index.
- Conditions
- Scarring, Spinal Stenosis, Herniated Disc
- Trial name
- NCT02300909
- Testing
- Lumbar Decompression Surgery, Microdiscectomy Surgery, Dehydrated Human Amnion/Chorion Membrane (dHACM)
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- MiMedx Group, Inc.
Degenerative Disc Disease, Spinal Stenosis
Burst Biologics Spinal Fusion Registry
A multicenter patient registry was created with aim of documenting how spine and neurosurgeons are utilizing Burst Biologics products along with patient outcomes.
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylitis, Spondylolisthesis
- Trial name
- NCT03064802
- Testing
- BioBurst Fluid, Burst Allograft
- Where
- 4 sites in United States
- Volunteers
- 450 people
- Sponsor
- Burst Biologics
Intervertebral Disc Herniation, Back Pain
Immune Response During the Conservative and Minimal Invasive Treatment of Pain Caused by Lumbar Disc Herniation
Bulging of the intervertebral disc in the lumbar part of the spine is one of the most common degenerative changes of the spine in the elderly population, which causes various symptoms such as radicular pain.
- Conditions
- Intervertebral Disc Herniation, Back Pain, Analgesic Nephropathy, Inflammatory Response
- Trial name
- NCT06545812
- Testing
- Transforaminal epidural steroid injection, Physical therapy for disc herniation
- Where
- Croatia
- Volunteers
- 128 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Dorsal Root Ganglion Intervention Treatments
This study applies 3D-printed customized guide plate in assisting the accurate puncture in transforaminal epidural steroid injection (TFESI) combined with pulsed radiofrequency (PRF) treatment.
- Trial name
- NCT05403775
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Lumbar Radiculopathy
Lumbar Transforaminal Epidural Corticosteroid Injection(s) Versus Defined Physical Therapy
The purpose of this research study is to look at two of the common forms of treatment for this condition: physical therapy and epidural steroid injection.
- Trial name
- NCT01443819
- Testing
- Lumbar Transforaminal Epidural Corticosteroid Injection, Physical Therapy, Observation
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Cervical Radiculopathy, Cervical Radicular Pain
Effect of Myofascial Release Technique in Patients with Unilateral Cervical Radiculopathy
The aim of the study is to investigate the effectiveness of myofascial release technique on pain, range of motion, muscle strength, functionality and quality of life in individuals diagnosed with cervical radiculopathy with…
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Cervical; Hernia, Cervical Disc Disease
- Trial name
- NCT04597112
- Testing
- Myofascial Release Technique, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital
Lumbar Disc Herniation
Microendoscopic Lumbar Discectomy: A Study of 100 Cases
Evaluate the outcome of micro endoscopic discectomy (MED) by tubular retractors on safety and efficacy of the technique.
- Trial name
- NCT03359564
- Testing
- micro endoscopic discectomy
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Neck Pain, Cervical Disc Herniation
Comparison of Conservative Treatment and Graston and Cup Applications in Patients With Cervical Disc Herniation
The aim of the study is to examine the effects of graston and dry cupping techniques applied in addition to the conservative treatment program on neck awareness, grip strength, balance and sleep quality in patients with cervical…
- Trial name
- NCT06003907
- Testing
- conventional, traditional and complementary medicine methods
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Uskudar University
Cervical Disc Herniation
Sensory and Functional Impairments in Cervical Disc Herniation
The aim of the study was to evaluate the levels of somatosensory perception, pain threshold and kinesiophobia in individuals with SDH, to examine their relationship with upper extremity functional skills and to compare them with…
- Trial name
- NCT07282522
- Testing
- Somatosensory Perception Tests, The Visual Analog Scale, Pain Threshold and Tolerance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Inonu University
Lumbar Disc Degeneration, Lumbar Disc Herniation
Human Umbilical Cord Mesenchymal Stem Cells For the Treatment of Lumbar Disc Degeneration Disease
This study aims to investigate the safety and efficiency of Human Umbilical Cord Mesenchymal Stem Cells (hUCMSC) for treating lumbar disc degeneration diseases.
- Trial name
- NCT04414592
- Testing
- human umbilical cord mesenchymal stem cells
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Impact of Muscle Degeneration in Chronic Low Back Pain
Surgical interventions for the removal of intervertebral disc fragments or to enlarge a narrow spine canal are commonly performed worldwide and are considered efficient.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Radiculopathy, Back Pain
- Trial name
- NCT04273828
- Testing
- Lumbar decompressive surgery
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Hospital Israelita Albert Einstein
Lumbar Disc Herniations
Clinical Effects of Moxibustion Combined With Tailored Baduanjin Exercise Programs on Early Postoperative Rehabilitation in Lumbar Disc Herniation Patients Undergoing Minimally Invasive Surgery
This study is a single-center randomized controlled trial, aiming to explore the effect of moxibustion combined with the modified Baduanjin exercise regimen on the early rehabilitation of patients with lumbar disc herniation…
- Trial name
- NCT07015658
- Testing
- Baduanjin, Moxibustion, Conventional intervention
- Volunteers
- 120 people
- Sponsor
- Suyun Liu