Clinical trials: Prolapsed Intervertebral Disc
Lumbar Disc Herniation, Lumbar Degenerative Disease
Multivariate Analysis and Machine Learning Model Risk Prediction of Recurrent Pain After PLIF Surgery for Degenerative Lumbar Spine Disease At Long-term Follow-up
The study was a clinical retrospective study designed to investigate risk factors for long-term recurrent pain after PLIF in patients with lumbar degenerative disease and to improve patient outcomes
- Conditions
- Lumbar Disc Herniation, Lumbar Degenerative Disease, Sarcopenia
- Trial name
- NCT06622356
- Testing
- MRI with Eovist
- Where
- China
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Hao Liu
Low Back Pain, Physical Therapy
Evaluation of the Effectiveness of Physical Therapy for Low Back Pain According to Magnetic Resonance Imaging Findings
Low back pain is a common musculoskeletal disorder associated with substantial disability and reduced quality of life. Although magnetic resonance imaging (MRI) is frequently used to identify structural spinal abnormalities, the…
- Conditions
- Low Back Pain, Physical Therapy, Lumbar Degenerative Disc Disease, Lumbar Disc Herniation
- Trial name
- NCT07648927
- Testing
- Standard Physical Therapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bahçeşehir University
Low Back Pain, Lumbar Disc Disease
Efficacy of Mechanical Traction and Spinal Decompression Treatments in Patients With Low Back Pain
Motorized traction and non-surgical spinal decompression treatments are relatively new treatments for which there is insufficient evidence in the literature.
- Conditions
- Low Back Pain, Lumbar Disc Disease, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT05617924
- Testing
- Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Afyonkarahisar Health Sciences University
Degenerative Disc Disease
PEEK and Allograft Spacers Evaluation in Spinal Fusion Surgeries
Purpose The primary purpose of this study is to prospectively compare clinical and radiographic clinical outcomes in patients undergoing cervical or lumbar interbody fusions and randomized to receive either polyetheretherketone…
- Trial name
- PEEK (NCT01406405)
- Testing
- Posterior/Transforaminal Lumbar Interbody Fusion (P/TLIF), Anterior Cervical Discectomy and Fusion (ACDF)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Justin Parker Neurological Institute
Cervical Lordosis Rehabilitation
Does Improvement Towards a Normal Cervical Sagittal Configuration Aid in the Management of Lumbosacral Radiculopathy
A randomized controlled study with six months follow-up will be conducted to investigate the effects of sagittal head posture correction on 3D spinal posture parameters, back and leg pain, disability, and S1 nerve root function…
- Trial name
- NCT05553002
- Testing
- Deneroll cervical extension traction, Traditional treatment
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Pain, Myofacial, Pain, Neck
Does Dry Needling Affect Treatment Outcomes of Interlaminar Epidural Steroid Injection in Cervical Disc Herniation?
Chronic neck pain is among the most frequently seen chronic painful conditions. As an important cause of disability, chronic neck pain is a musculoskeletal disorder that negatively affects quality of life.
- Conditions
- Pain, Myofacial, Pain, Neck, Pain, Chronic
- Trial name
- NCT04914637
- Testing
- Cervical interlaminar epidural steroid injection, Dry needling
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Marmara University
Analgesia
Regional Blocks for Lumbar Disc Surgery Analgesia
Objective The goal of this prospective randomized controlled experiment was comparing the analgesic efficacy, opioid needs, and adverse effect profiles of Paravertebral Block (PVB), Thoracolumbar Interfascial Plane Block (TLIP)…
- Trial name
- NCT06933641
- Testing
- Regional Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Postoperative Recovery, Lumbar Disc Herniation
Lower Back Muscle Size and Recovery After Lumbar Disc Herniation Surgery
Recovery after surgery for a herniated disc in the lower back differs from person to person. The size of the muscles around the lower spine may be related to recovery, but this relationship is not well understood.
- Trial name
- NCT07768241
- Testing
- Preoperative Psoas and Multifidus Muscle Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lumbar Disc Herniation
Percutaneous Discectomy to Treat Symptomatic Lumbar Disc Herniation : Evaluation of Clinical Efficiency, Patient Reported Outcomes and Economical Impact by Assessing Time Before Return to Work and Duration of Hospitalization Stay
This study aims to evaluate the clinical (pain) and functional (patient reported outcomes) efficacy of percutaneous discectomies under CT guidance to treat lumbar disc herniations resistant to conservative treatment and nerve…
- Trial name
- NCT05772143
- Testing
- Percutaneous discectomies under CT
- Where
- France
- Volunteers
- 87 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Lumbar Disc Herniation
A Prospective, Randomized, Multicenter Study to Demonstrate the Superiority of the Barricaid to Discectomy for Primary Lumbar Disc Herniation
A randomized study to demonstrate the superiority of the Barricaid® when used in conjunction with limited discectomy, compared to limited discectomy alone, with regard to preventing reherniation and the recurrence of pain or…
- Trial name
- NCT01283438
- Testing
- Barricaid, Standard of Care
- Where
- 21 sites in Austria, Belgium and 4 more
- Volunteers
- 554 people
- Sponsor
- Intrinsic Therapeutics
Cervical Disc Herniation, Chronic Pain
Action Observation and Motor Imagery Training in Cervical Disc Herniation
Cervical disc herniation is a common degenerative spinal disorder associated with chronic neck pain, impaired cervical function, reduced motor control, and decreased quality of life.
- Conditions
- Cervical Disc Herniation, Chronic Pain, Kinesiophobia, Cervical Pain
- Trial name
- NCT07781982
- Testing
- Conventional Physiotherapy, Action Observation and Motor Imagery Training
- Volunteers
- 36 people
- Sponsor
- İrem Çetinkaya
Spinal Stenosis Lumbar, Disc Herniation, Lumbar
More Realistic Spine Patients: Assessing the Effect of Dialogue Support Tool.
This multicenter randomized controlled trial will evaluate whether an additional preoperative study visit using the Dialogue Support (DS) tool improves patient information, expectations, and outcomes among adults scheduled for…
- Conditions
- Spinal Stenosis Lumbar, Disc Herniation, Lumbar, Degenrative Disc Disease
- Trial name
- MORESP (NCT07788872)
- Testing
- Dialogue Support Study Visit
- Where
- 2 sites in Norway
- Volunteers
- 440 people
- Sponsor
- University Hospital, Akershus
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Prevalence of Neuropathic Pain After Non-instrumented Lumbar Spinal Surgery
Chronic neuropathic pain following lumbar spine surgery is often under-diagnosed and difficult to relieve. It can persist long after the operation, sometimes for months or even years, and has a major impact on the quality of life…
- Trial name
- LomboDN (NCT06763224)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier de Colmar
Herniated Disc, Radiculopathy
Slotted Hole Versus Fixed Hole C-Tek
The purpose of this study is to compare the fusion rates between the EBI, LLC C-Tek™ Anterior Cervical Plate, Slotted Hole Design versus the Fixed Hole Design.
- Conditions
- Herniated Disc, Radiculopathy, Spondylolysis
- Trial name
- NCT00585923
- Testing
- Fixed hole C-Tek™ Plate, Slotted hole C-Tek™ Plate
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Zimmer Biomet
Lumbar Disc Herniation Surgery, Mechanical Ventilation
Flow-Controlled Versus Volume-Controlled Ventilation in Lumbar Disc Herniation Surgery
This prospective randomized trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on intraoperative airway pressures and oxygenation in patients undergoing lumbar disc…
- Trial name
- NCT07614555
- Testing
- FCV Group, VCV Group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Etlik City Hospital
Lumbar Disc Herniation, Lumbar Disc Disease
Ultrasound-Guided vs. Surgeon-Performed (Free-hand) Erector Spinae Plane Block
The aim of this study is to compare the analgesic efficacy of ultrasound-guided (USG) lumbar Erector Spinae Plane Block (ESPB) performed by an anesthesiologist versus a "free-hand" ESPB performed intraoperatively by the surgeon…
- Trial name
- NCT07454304
- Testing
- US-guided ESPB., Surgeon-performed (Free-hand) ESPB.
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Medipol University
Intervertebral Disc Herniation, Back Pain
Immune Response During the Conservative and Minimal Invasive Treatment of Pain Caused by Lumbar Disc Herniation
Bulging of the intervertebral disc in the lumbar part of the spine is one of the most common degenerative changes of the spine in the elderly population, which causes various symptoms such as radicular pain.
- Conditions
- Intervertebral Disc Herniation, Back Pain, Analgesic Nephropathy, Inflammatory Response
- Trial name
- NCT06545812
- Testing
- Transforaminal epidural steroid injection, Physical therapy for disc herniation
- Where
- Croatia
- Volunteers
- 128 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Cervical Disc Herniation
Effect of Neck vs. Combined Neck-Lumbar Mobilization on Pain and Motion in Cervical Disc Herniation
Background To assess the effectiveness of Kaltenborn-Evjenth Orthopedic Manual Therapy (KEOMT) applied to cervical-only mobilization versus both lumbar and cervical regions on pain intensity and range of motion (ROM) in…
- Trial name
- NCT06858605
- Testing
- Kaltenborn-Evjenth Orthopedic Manual Therapy (KEOMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Fenerbahce University
Intervertebral Disk Degeneration, Intervertebral Disk Displacement
Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™
Anterior cervical discectomy and fusion (ACDF) has shown good treatment results for a variety of cervical spine diseases such as herniated intervertebral disc (HIVD), cervical spondylotic radiculopathy (CSR) and cervical…
- Conditions
- Intervertebral Disk Degeneration, Intervertebral Disk Displacement, Ossification of Posterior Longitudinal Ligament
- Trial name
- NCT01615328
- Testing
- Cervios ChronOs, Bonion
- Where
- South Korea
- Volunteers
- 85 people
- Sponsor
- Seoul National University Hospital
Pain, Back, Spinal Stenosis
PREventing Pain After Surgery
The present study aims to adapt and modify a brief presurgical Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use.
- Conditions
- Pain, Back, Spinal Stenosis, Disc Herniation, Spondylosis
- Trial name
- PREPS (NCT05306665)
- Testing
- ACT intervention
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Brigham and Women's Hospital