Clinical trials: Prolapsed Intervertebral Disc
Progressive Relaxation Exercise, Hernia
Effects of Relaxation Exercises on Fear of Movement, Pain, and Quality of Life in Lumbar Disc Herniation Patients
This study evaluates whether progressive relaxation exercises can reduce fear of movement, pain, and improve quality of life in patients with lumbar disc herniation.
- Conditions
- Progressive Relaxation Exercise, Hernia, Pain, Kinesiophobia
- Trial name
- NCT07419958
- Testing
- progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Hasan Kalyoncu University
Lumbar Disc Herniation
Collagenase Chemonucleolysis vs Percutaneous Endoscopic Lumbar Discectomy (PELD) for Lumbar Disc Herniation
Lumbar disc herniation compressed the nerve cause pain, numbness, weak legs called sciatica, which seriously decrease the quality of life and work efficiency.
- Trial name
- NCT05330806
- Testing
- Collagenase chemonucleolysis, Percutaneous endoscopic lumbar discectomy (PELD)
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Shenzhen People's Hospital
Lumbar Disc Herniation
Lumbar Epidural Analgesia Versus Local Anesthesia With Dexmedetomidine Infusion in Endoscopic Lumbar Discectomy
To compare between local anesthesia combined with intravenous Dexmedetomidine and epidural analgesia as regard the effectiveness and patient satisfaction during percutaneous transforaminal endoscopic discectomy.
- Trial name
- NCT05850455
- Testing
- Dexmedetomidine Hydrochloride 'Precedex' combined with, Lumbar epidural analgesia with Bupivacaine 0.25% 'Sunnypivacaine', General anesthesia
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Ain Shams University
Degenerative Disc Disease, DDD
Biologic Injection For Adults With Lumbar Disc Herniation
The goal of this clinical trial is to find out whether adding a bone-marrow aspirate concentrate (BMAC) injection during surgery can improve recovery in adults undergoing lumbar microdiscectomy for a lumbar disc herniation.
- Conditions
- Degenerative Disc Disease, DDD, Degenerative Disc Disease Lumbar, Degenerative Disc Disease, Lumbar
- Trial name
- BMAC (NCT07386548)
- Testing
- Bone Marrow Aspirate Concentrate (BMAC)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Weill Medical College of Cornell University
Back Pain, Neck Pain
Treatment of Chronic Thoracic and Neck and Upper Extremity Pain
To study improvements or lack thereof with the interlaminar epidural patients with or without steroids experiences mid back, upper back or neck pain with or without chest wall and upper extremity pain of at least 6-months…
- Trial name
- NCT01071369
- Testing
- Xylocaine, Xylocaine and Celestone
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Neuropathic Pain, Chronic Postsurgical Pain
Efficacy of an Intraoperative Periradicular Application of Platelet Rich Fibrin (PRF) on the Intensity of Residual Post-surgical Neuropathic Pain After a Surgery for Disc Herniation
The prevalence of post-surgical lumbar neuropathic radiculopathy is approximately 30%. Poor response to the treatments recommended for neuropathic pain, namely antidepressants and/or gabapentinoids, requires the development of…
- Trial name
- NeuroPRF (NCT05196503)
- Testing
- Treatment
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Thoracic Disc Herniation
The Incidence of Thoracic Disc Herniation in Patients Presenting With Chronic Upper Back Pain
Patients who applied to the Private Medar Hospital between February 2016 and February 2021 with chronic upper back pain and were diagnosed with Thoaracic Disc Herniatin (TDH) (with Thoracic vertebral MRI) and followed up for at…
- Trial name
- NCT05313997
- Testing
- Diclofenac Sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 194 people
- Sponsor
- Kocaeli University
Radiculopathy, Spinal Stenosis
Steroid Injections Given at the "Level of MRI Pathology" Versus at the "Level of Clinical Symptoms" to See if One is More Effective Than the Other.
Patients are being asked to participate in a research study because the patients are being treated for low back pain and the patients have decided to have an epidural steroid injection.
- Conditions
- Radiculopathy, Spinal Stenosis, Intervertebral Disc Displacement
- Trial name
- NCT02196883
- Testing
- Transforaminal Epidural Steroid Injection
- Where
- United States
- Sponsor
- State University of New York - Upstate Medical University
Pain, Back
The Effect of Magnesium Deficiency on Transforaminal Epidural Steroid Injection Success: An Observational Study
Transforaminal epidural steroid injection (TFESE) is an interventional method frequently used in the treatment of radicular pain due to disc herniation.
- Trial name
- NCT06551792
- Testing
- Effect of Serum Magnesium Level on the Success of Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pain, Back, Spinal Stenosis
PREventing Pain After Surgery
The present study aims to adapt and modify a brief presurgical Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use.
- Conditions
- Pain, Back, Spinal Stenosis, Disc Herniation, Spondylosis
- Trial name
- PREPS (NCT05306665)
- Testing
- ACT intervention
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Brigham and Women's Hospital
Degenerative Disc Disease, Disc Herniation
Adjacent Level Anterior Cervical Fusion: SeaSpine Shoreline Versus Removal of Previously Implanted Plate and Replating
The purpose of this study is to evaluate the efficacy of SeaSpine Shoreline device in surgery of the cervical spine.
- Trial name
- NCT06415136
- Testing
- SeaSpine Shoreline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Research Source
Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation
Multicentric Registry for the Detection of C5 Palsy After Anterior Cervical Discectomy and Fusion
Detect the reason for the frequently occurring C5 palsy after anterior cervical discectomy and fusion
- Conditions
- Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation, Suspected Cervical Spine Instability
- Trial name
- C5registry (NCT02875431)
- Testing
- Patients undergo ACDF or cervical vertebral body replacement
- Where
- Germany
- Volunteers
- 1,087 people
- Sponsor
- Technical University of Munich
Motor Deficits, Lumbar Discectomy
Investigation of Preoperative Factors Influencing the Outcome of Motor Deficits in Patients Undergoing Lumbar Microdiskectomy
Lumbar disc herniations may result in lower limb weakness. In such cases, there is a strong indication for surgical intervention through microdiscectomy.
- Conditions
- Motor Deficits, Lumbar Discectomy, Muscle Weakness, Paresis
- Trial name
- NCT07413302
- Where
- 3 sites in Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
Female Patients Diagnosed With LDH at L4-S1
The Effect of Hyperextension Exercises In Lumbal Disc Hernia
The aim of this study was to examine the short-term effect on pain severity, disability level, flexibility and performance level of McKenzie hyperextension exercises applied in addition to conventional physiotherapy approaches in…
- Trial name
- NCT06158685
- Testing
- Study Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Mehmet GÖĞREMİŞ
Pain, Disability
Do Benzodiazepines Improve the Outcome of Mechanical Physiotherapy for Lumbar Disk Prolapse
Sixty patients were randomized to receive either placebo or diazepam in addition to mechanical physiotherapy and analgesics for the first 7 days of conservative treatment of clinically and radiologically confirmed lumbar disk…
- Conditions
- Pain, Disability, Paresis
- Trial name
- NCT00533286
- Testing
- benzodiacepine
- Sponsor
- University Hospital Tuebingen
Low Back Pain, Disc, Herniated
Motor Control Mechanisms by CNS of Tuina in Patients With Lumbar Disk Herniation
Lumbar disk herniation (LDH)is a prevalent health problem around the world. It can cause symptoms of low back pain, numbness or weakness.The understanding of low back pain in traditional Chinese medicine(TCM) theory"unbalanced…
- Trial name
- NCT03475095
- Testing
- Tuina
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Radiculopathy, Cervical
The Norwegian Cervical Arthroplasty Trial
The study will compare cervical arthroplasty with cervical discectomy and fusion, in the treatment of cervical radiculopathy. The 0-hypothesis is that there is no difference between the two methods, when comparing primary and…
- Trial name
- NORCAT (NCT00735176)
- Testing
- Cervical arthroplasty, Anterior cervical discectomy and fusion (ACDF)
- Where
- Norway
- Volunteers
- 136 people
- Sponsor
- Norwegian University of Science and Technology
Lumbal Disc Herniation, Capacitive and Resistive Electric Transfer Therapy
Tecar Therapy in Lumbar Disc Herniation
This randomized controlled trial investigates the effects of Tecar therapy on pain intensity and functional status in patients with lumbar disc herniation.
- Conditions
- Lumbal Disc Herniation, Capacitive and Resistive Electric Transfer Therapy, Exercise Training
- Trial name
- LDH-TECAR (NCT07082660)
- Testing
- High-Frequency Capacitive-Resistive Diathermic Current Therapy (TECAR), Lumbal Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Şebnem Nur Alkan
Spinal Stenosis Lumbar, Disc Herniation, Lumbar
More Realistic Spine Patients: Assessing the Effect of Dialogue Support Tool.
This multicenter randomized controlled trial will evaluate whether an additional preoperative study visit using the Dialogue Support (DS) tool improves patient information, expectations, and outcomes among adults scheduled for…
- Conditions
- Spinal Stenosis Lumbar, Disc Herniation, Lumbar, Degenrative Disc Disease
- Trial name
- MORESP (NCT07788872)
- Testing
- Dialogue Support Study Visit
- Where
- 2 sites in Norway
- Volunteers
- 440 people
- Sponsor
- University Hospital, Akershus
Lumbar Disc Herniation
Erector Spinae Plane Block and Modified-Thoracolumbar Interfascial Plane Block Following Lumbar Spinal Surgery
Ultrasound (US)-guided peripheral nerve blocks have been used increasily due to the advantages of ultrasound in anesthesia practice. TLIP block is one of these nerve blocks performed under US guidance.
- Trial name
- NCT04073095
- Testing
- Erector spinae plane block (Group E), modified-thoracolumbar interfascial plane block (Group T)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University