Clinical trials: Prolonged Mechanical Ventilation
Preterm Birth
Repercussions of Respiratory Physiotherapy in Preterm Infants Under Mechanical Ventilation
Respiratory diseases are a major morbidity and mortality causes of neonatal requiring mechanical ventilation, especially in newborn preterm infants (PN), thus respiratory therapy becomes increasingly necessary in order to…
- Trial name
- preterm (NCT03159039)
- Testing
- Conventional Physiotherapy, Prolonged slow exhalation technique
- Volunteers
- 43 people
- Sponsor
- Universidade Cidade de Sao Paulo
PICS
Impact of Persistent Inflammation-Immunosuppression-Catabolism Syndrome (PICS) on the Respiratory Physiology in Patients With Prolonged Mechanical Ventilation
Past research on PICS has mainly focused on the predictability and prognosis of PICS occurrence in ICU patients. Still, there is currently insufficient research on the role of PICS in the care setting of patients who have…
- Trial name
- NCT07002710
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Neurosurgical Procedures, Neurosurgical Patients
Prolonged Mechanical Ventilation in Neurosurgical Patients:
The study was carried out at the neurosurgical operating theater and neurosurgical intensive care unit, Maharaj Nakorn Chiang Mai University-Hospital.
- Conditions
- Neurosurgical Procedures, Neurosurgical Patients, Prolonged Mechanical Ventilation
- Trial name
- NCT06591624
- Testing
- Prolonged Mechanical Ventilation, remain intubation after surgery
- Where
- Thailand
- Volunteers
- 340 people
- Sponsor
- Chiang Mai University
Critical Illness
Determination of Risk Factors and Mortality for Pediatric Chronic Critical Illness in Turkey
It is predicted that the number of Pediatric Chronic Critical Illness increases similar to adult all over the world. The prevalence of Pediatric Chronic Critical Illness in Turkey is unknown.
- Trial name
- NCT03308513
- Where
- Turkey (Türkiye)
- Volunteers
- 888 people
- Sponsor
- Yuzuncu Yil University
Prolonged Mechanical Ventilation, Critical Illness
Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure
The main objective of the study is to determine whether a subnormal serum creatinine value upon admission to the Post-ICU Care Unit predicts the need for prolonged ventilatory support.
- Trial name
- SECRET-VENT (NCT07177183)
- Testing
- Dietary supplement creatine, No intervention
- Where
- 2 sites in Czechia
- Volunteers
- 492 people
- Sponsor
- University Hospital Ostrava
Critical Illness
Specialized Treatment, Rehabilitation and Outcome in Patients With Prolonged Critical Illness
This prospective observational study aims to describe the outcome for patients with persistent or chronic critical illness treated at Remeo, a clinic specialized for patients in need of prolonged intensive care and intensive care…
- Trial name
- CritillPro (NCT04247607)
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Remeo AB
Ventilator Weaning, Respiratory Failure
Assessments of Diaphragm-pleural Mechanics During the Weaning From Prolonged Mechanical Ventilation
Weaning failure from mechanical ventilator is commonly seen in respiratory failure and increases duration of ventilator use, ICU stay, ventilator associated pneumonia and even mortality.
- Trial name
- NCT03842280
- Testing
- Diaphragm ultrasound assessment & Esophageal pressure measurement
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Mechanical Ventilation, Surgeries Undergoing General Anesthesia
Preoperative Characteristics and Outcomes of Neonates Undergoing Surgical Procedures in the NICU
This retrospective observational study evaluates neonates who underwent surgical procedures during admission to a neonatal intensive care unit (NICU).
- Trial name
- NeoSurg-Resp (NCT07793812)
- Testing
- Surgical Procedures
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Ayberk Ozkavakli
Premature Birth, Respiration Failure
Predictors of Prolonged Mechanical Ventilation in Preterm Infants
This prospective cohort study aims to identify the independent predictors of prolonged mechanical ventilation in preterm infants admitted to the Neonatal Intensive Care Unit of Assiut University Children Hospital.
- Conditions
- Premature Birth, Respiration Failure, Bronchopulmonary Dysplasia
- Trial name
- NCT07821632
- Volunteers
- 100 people
- Sponsor
- Assiut University
COVID-19, Mechanical Ventilation
Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome
This multicentric prospective clinical practice study aims at evaluating clinical factors associated with a prolonged invasive mechanical ventilation and other outcomes such as mortality and ICU length of stay in patients…
- Conditions
- COVID-19, Mechanical Ventilation, Quality of Life, Radiologic Increased Density of Lung
- Trial name
- NCT04411459
- Testing
- Invasive mechanical ventilation
- Where
- 20 sites in Italy
- Volunteers
- 470 people
- Sponsor
- Azienda Usl di Bologna
Chronic Ventilator Dependency
HFCWO in Prolonged Mechanical Ventilation Patients
The effectiveness, safety and tolerance/comfort of high-frequency chest wall oscillation (HFCWO) in prolonged mechanical ventilation patients remain unknown.
- Trial name
- NCT02077738
- Testing
- HFCWO (Hill-Rom Vest™ Airway Clearance System)
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Taichung Veterans General Hospital
Ventilator Weaning
Oxygen Uptake in Weaning of Patients From Prolonged Mechanical Ventilation
1.Research hypothesis: during weaning patient from prolonged mechanical ventilation, if the work load caused by weaning was below the patient's AT, oxygen uptake will be constant.
- Trial name
- NCT03433105
- Where
- Taiwan
- Volunteers
- 157 people
- Sponsor
- National Taiwan University Hospital
Depression
Preventing Depression in People Receiving Mechanical Ventilation in an Intensive Care Unit
This study will determine the effectiveness of antidepressant medication in preventing depression and improving recovery in people who have been supported by mechanical ventilators in an intensive care unit (ICU).
- Trial name
- NCT00872027
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Minnesota
Tracheostomy Complication, Diaphragm Disease
Assessment of the Effect of an Inspiratory Muscle Training Regimen on Decannulation Time in Tracheostomized Subjects
The objective of this project is to evaluate the effect of applying an individualized inspiratory muscle training regimen, combining strength and endurance exercises over a two-week period, on improving maximum inspiratory…
- Trial name
- NCT06684392
- Testing
- Inspiratory muscle training
- Where
- Chile
- Volunteers
- 56 people
- Sponsor
- Hospital Dr. Franco Ravera Zunino
Respiratory Failure
Electrical Stimulation in Patients With Prolonged Mechanical Ventilation
Muscle atrophy and diaphragm dysfunction are common complication in patients with prolong mechanical ventilator (PMV) and is associated with increased rate of weaning failure and days of hospitalization.
- Trial name
- NCT02227810
- Testing
- electrical stimulation (high frequency), electrical stimulation (low frequency)
- Where
- Taiwan
- Volunteers
- 53 people
- Sponsor
- Chang Gung Memorial Hospital
Larynx Disease
Swallowing Disorders After Prolonged Mechanical Ventilation
Epidemiology study for evaluation of incidence of swallowing disorders (SD) after prolonged invasive ventilation (more than seven days), using a clinical statement.
- Trial name
- Deglutube (NCT01360580)
- Where
- 2 sites in France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Rouen
Mechanical Ventilation, Weaning
Automated Ventilator Controlled Weaning vs Daily Spontaneous Breathing Trial in Difficult to Wean ICU Patients
This study will compare Drager Smart Care (SC), a commercially available automated ventilator controlled weaning mode to the current daily spontaneous breathing trial (SBT) weaning protocol.
- Trial name
- NCT00813839
- Testing
- daily weaning trails
- Where
- United States
- Sponsor
- University of California, San Francisco
Wounds and Injuries, Ventilation Therapy; Complications
CT-based Model for Predicting Prolonged Weaning in Patients With Abdominal Trauma
Critically ill patients often require tracheal intubation for mechanical ventilation, and timely weaning is crucial for airway management and reducing complications.
- Trial name
- NCT06339073
- Testing
- mechanical ventilation
- Where
- China
- Volunteers
- 1,023 people
- Sponsor
- Jinling Hospital, China
Mechanical Ventilation
Retrospective Study on Prolonged Sedation Effects With Inhaled Agents in PICU
The objective of the study is to evaluate the effects of halogenated gases on sedation and analgesia, to describe the tolerance and to determine the risk factors for failure, in pediatric intensive care patients during prolonged…
- Trial name
- RESPIRE (NCT05064592)
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ventilator Dependent
Short Effects of SIMT and EM in Prolonged Mechanically Ventilated Patients
Using mechanical ventilation for more than 18 hours can affect respiratory muscle and postural muscle control, making it difficult to wean off the ventilator and reducing mobility. The aim of this study is to: 1.
- Trial name
- NCT06368089
- Testing
- Inspiratory muscle training (IMT) group, Early mobilization (EM) group
- Where
- Thailand
- Volunteers
- 46 people
- Sponsor
- Prince of Songkla University