Clinical trials: Prone Position, open to volunteers
Urolithiasis
Retrolaminar Block Analgesia and Patient Comfort During Prone ESWL
The purpose of this prospective, observational study is to evaluate the effect of retrolaminar block (RLB) on patient comfort and analgesic effectiveness during extracorporeal shock wave lithotripsy (ESWL) procedures.
- Trial name
- NCT07177625
- Testing
- Retrolaminar block, Sedoanalgesia, No Intervention / None
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
ARDS (Acute Respiratory Distress Syndrome), Respiratory Failure
Prone Position Assessed by 3D EIT
To investigate global and regional changes in lung ventilation and perfusion induced by prone position in ARDS patients assessed by 3D-EIT. And to investigate the difference between 2D-EIT and 3D-EIT in prone position monitoring.
- Trial name
- NCT07083973
- Testing
- Prone position
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS), Surfactant Dysfunction
Infants With Severe Acute Respiratory Distress Syndrome: The Prone Trial
The main objective is to determine the short-term effect of prone positioning in infants with infection-associated severe acute respiratory distress syndrome.
- Conditions
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS), Surfactant Dysfunction, Infant
- Trial name
- NCT05002478
- Testing
- Prone positioning
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Medical University of Vienna
Procedural Pain, Procedural Anxiety
Virtual Reality (VR) Audiovisual Distraction to Reduce Pain and Anxiety for Prone Pain Procedures
This study evaluates whether virtual reality (VR) audiovisual distraction can reduce pain, anxiety, and the need for pain and anxiety medications during prone pain procedures, compared to standard care alone.
- Trial name
- NCT07779083
- Testing
- Virtual Reality (VR) Audiovisual Distraction
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- University of California, Davis
Acute Respiratory Distress Syndrome, Mechanical Ventilation
Physiological Studies in the Prone Position in Patients With ARDS
The purpose of this study is to observe the changes of physiological indicators such as ventilation and oxygenation in the prone position of ARDS patients, to observe the change trend of each patient's indicators, and to observe…
- Conditions
- Acute Respiratory Distress Syndrome, Mechanical Ventilation, Prone Positioning
- Trial name
- NCT06586736
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Newborn Infant, Newborn Health
The Effect of Different Positions Given to the Newborn During Delayed Cord Clamping on Physiological Indicators and Comfort
During intrauterine life, the fetus is connected to the mother via the placenta; with birth, the extrauterine adaptation process begins.
- Conditions
- Newborn Infant, Newborn Health, Delayed Cord Clamping
- Trial name
- Cord Clamping (NCT07719751)
- Testing
- Prone position, Left side lying position
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mersin University
Breast Cancer, Breast - Female
Improving Combined PET/CT and MRI of the Breast Using Dedicated Breast Positioning and Image Registration
The goal of this clinical trial is to improve the combined use of PET/CT and MRI for imaging of the breast. PET/CT and MRI are usually performed in different body positions, which can change the shape and position of the breast…
- Trial name
- REPOSE-Breast (NCT07883460)
- Testing
- Prone Breast PET/CT Acquisition
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Universität Münster
Pressure Ulcers Prevention in Prone Positioning in Intensive Care
Pressure Sore Prevention Strategy for the Prone Position
The aim of this clinical trial is to determine whether 5-layer hydrocellular dressings are effective in preventing the development of pressure sores during prone positioning in the intensive care unit.
- Trial name
- DERM-H-PROTECT (NCT06442657)
- Testing
- Hydrocellular dressing, Hydrocolloids dressing
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Caen
Breast Cancer
Two Versus One Week Breast Radiotherapy (RT)
This study is comparing two different radiation therapy approaches for early breast cancer to see which one is better for patients.
- Trial name
- PRATO (NCT06960707)
- Testing
- Radiation therapy - 1 week, Radiation therapy - 2 weeks
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- Weill Medical College of Cornell University
Acute Hypoxemic Respiratory Failure, Obesity
Adiposity Distribution in Acute Respiratory Failure
Acute Hypoxemic Respiratory Failure (AHRF) is a condition in which injury to the lungs impairs the ability of the air sacs (alveoli) to ventilate and exchange oxygen.
- Trial name
- NCT07019987
- Testing
- PEEP Titration Using Electrical Impedance Tomography (EIT), Body Positioning: Supine and Prone
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Maurizio F. Cereda, MD
Prone Position, Child Development
Supporting Infant Development Through Tummy Time, Positioning, and Limiting Baby Gear
The goal of this clinical trial is to examine the impact of an educational intervention on infant motor skill development. The main question it aims to answer is: Question 1) Does exposure to an educational intervention on infant…
- Trial name
- NCT05878275
- Testing
- Parent Informational Session
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Tennessee
Respiratory Mechanics
Ultrasonographic Abdominal Fat Thickness and Driving Pressure During Prone Spinal Surgery
This prospective observational study aims to evaluate the association between preoperative abdominal subcutaneous fat thickness measured by ultrasonography and intraoperative driving pressure in adult patients undergoing elective…
- Trial name
- NCT07723690
- Volunteers
- 120 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
ARDS (Acute Respiratory Distress Syndrome)
Lung EIT Image Guide Ventilation in ARDS
The goal of this multi-center randomized controlled clinical trial is to learn if an individualized, bedside electrical impedance tomography (EIT)-guided ventilation strategy (including EIT-guided prone positioning and PEEP…
- Trial name
- NCT07309783
- Testing
- Recruitment maneuver and PEEP setting guided by EIT, PEEP setting according to routine practice, Prone positioning guided by EIT
- Where
- China
- Volunteers
- 574 people
- Sponsor
- Peking Union Medical College Hospital
Lumbar Stabilization Surgery, Noninvasive Hemoglobin Monitoring
Effect of Prone Position on Continuous Noninvasive Hemoglobin Measurement
This prospective observational study aims to evaluate whether the prone position affects the agreement between noninvasive hemoglobin (SpHb) measurements and laboratory hemoglobin values in patients undergoing lumbar…
- Trial name
- NCT07823569
- Testing
- Prone Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Acute Respiratory Distress Syndrome (ARDS), Intensive Care Units (ICUs)
Assessment of the PEEP Responsiveness to Titrate End-expiratory Pressure and of the Need for Muscle Relaxation During Prone Positioning in Moderate-to-severe Acute Respiratory Distress Syndrome: A Master Protocol
Despite best supportive care, mortality of the Acute Respiratory Distress Syndrom (ARDS) remains high. In the absence of specific treatments, providing safe and efficient mechanical ventilation (MV) is key to survival.
- Trial name
- PEPER (NCT06849570)
- Testing
- Minimal distension, Maximal Recruitment, Prone position + early NMBAs
- Where
- 29 sites in France
- Volunteers
- 1,200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lumbosacral Radiculopathy
Clinical Outcomes of Prone and Supine Lumbar Traction Matched to Mechanical Bias in Flexion and Extension Subgroups With Lumbosacral Radiculopathy
Aim of the study is to identify specific patient subgroups that respond optimally to prone or supine traction based on mechanical diagnosis.
- Trial name
- NCT07786402
- Testing
- group A, Group B, Group C
- Volunteers
- 28 people
- Sponsor
- Al-Ahliyya Amman University
Postoperative Pain, Kidney Calculi
Nephrostomy Tract Infiltration for Pain Control After PCNL
This prospective, randomized, controlled clinical trial aims to evaluate the effectiveness of nephrostomy tract local anesthetic infiltration for postoperative pain control in patients undergoing prone percutaneous…
- Trial name
- NCT07721571
- Testing
- Bupivacaine, Intravenous Tramadol and Paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hitit University
Positive Pressure Extubation Techniques, Negative Pressure Extubation Techniques
Positive- vs Negative-Pressure Extubation in High-Risk Patients
In the intensive care unit (ICU), weaning from mechanical ventilation and extubation are critical clinical goals. Successful extubation not only significantly shortens mechanical ventilation duration but also reduces the…
- Conditions
- Positive Pressure Extubation Techniques, Negative Pressure Extubation Techniques, High-risk Patients Prone to Extubation Failure
- Trial name
- NCT07829627
- Testing
- Positive-pressure extubation, Negative-pressure extubation
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Shanghai Zhongshan Hospital
Pressure Injuries, Skin Failure
Barrier Functions oF Skin in ICU: SKIN-BAR
This study aims to investigate skin barrier function in intensive care unit (ICU) patients using biosensor-based measurements. Biophysical parameters including transepidermal water loss (TEWL), skin pH, stratum corneum hydration…
- Conditions
- Pressure Injuries, Skin Failure, Skin Abnormalities, Biophysical Parameters of Skin
- Trial name
- SKIN-BAR (NCT07560683)
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Koç University
Venous Thromboembolism (VTE)
Collaborative Risk-stratified Investigation in Thrombosis-prone Inpatients With Critical Illness: Anticoagulation With LMWH in Teens for ThromboProphylaxis (CRITICAL-Teens-TP).
Critically ill adolescents are at greatest risk for developing hospital-acquired venous thromboembolism. To date, no phase 3 randomized controlled trials have been conducted for pharmacological thromboprophylaxis as primary…
- Trial name
- NCT06628778
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 802 people
- Sponsor
- Johns Hopkins All Children's Hospital