Clinical trials: Prone Positioning
Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis
Assessing the Diagnostic Accuracy of Corrected Flow Time (FTc) and Pleth Variability Index (PVI) as Predictors of Fluid Responsiveness in Patients in the Prone Position Using the Jackson Table
Appropriate fluid management is an important part of anesthesia in patients undergoing surgery, and several dynamic indices have been suggested to have high predictability for fluid responsiveness in patients receiving mechanical…
- Conditions
- Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis, Spinal Fractures, Scoliosis or Tumors
- Trial name
- NCT02826889
- Testing
- Philips Intelivue MP70 monitor, Pleth Variability Index (PVI)
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Breast Cancer, Radiation Dermatitis
Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Prone Position
Radiotherapy (RT) is common in the treatment of breast cancer, however, 95% of breast cancer patients are at risk of developing acute and chronic skin toxicities known as radiation dermatitis (RD) which includes symptoms such as…
- Trial name
- NCT06915857
- Testing
- Topical Betamethasone
- Where
- Canada
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Hemodynamic Variation During Surgery
Mean Systemic Pressure Measurement During Prone Position Surgery
Venous return is driven by the pressure gradient between mean systemic pressure and right atrial pressure. However, mean systemic pressure is more a physiological concept than an available clinical measurement.
- Trial name
- NCT01957605
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Prone Position, Pressure Ulcer
Efficacy of HOFA Versus Hydrocolloid Dressings in the Prevention of PUs in Critically Ill Prone Patients
Introduction: Prone position (PP) treatment as a rescue strategy for patients with acute respiratory distress syndrome (ARDS) is a technique increasingly used in our daily practice and, as a result of the current health situation…
- Trial name
- NCT05198167
- Testing
- Hyperoxygenated fatty acids, Hydrocolloid dressings
- Where
- Spain
- Volunteers
- 262 people
- Sponsor
- Puerta de Hierro University Hospital
COVID-19
Postural Changes and Severe COVID-19
COVID-19 remains a widespread global epidemic, increasing morbidity, mortality, healthcare resource consumption, and socio-economic burden on patients worldwide.
- Trial name
- NCT05679440
- Testing
- Postural interventions based on pulmonary imaging
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Spinal Stenosis, Lumbosacral Region
Stability Comparison of TIVA and Sevoflurane in Prone Spinal Surgery(TIVA:Total Intravenous Anesthesia)
Key Points: 1. Objective: o To compare the effects of Total Intravenous Anesthesia (TIVA) and sevoflurane anesthesia on respiratory mechanics, hemodynamic parameters, and neuromonitoring during prone position spinal surgeries. 2.
- Trial name
- TIVA (NCT06558695)
- Testing
- Sevoflurane, TIVA
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Healthy
Anti-FLEX: Flexed Levering of Gluteal Vessels
The purpose of this study is to evaluate the effect of the gluteal vasculature in the prone and jackknife positions.
- Trial name
- NCT03286231
- Testing
- CT imaging
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Choledocholithiasis
Left Lateral Position and Prone Position for Endoscopic Retrograde Cholangiopancreatography
Endoscopic retrograde cholangiopancreatography (ERCP) has been widely used in diagnosis and treatment of pancreaticobiliary diseases. Traditionally, ERCP has been performed in the prone position.
- Trial name
- NCT02594475
- Testing
- Endoscopic retrograde cholangiopancreatography
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Acute Respiratory Distress Syndrome, Prone Position
Effect of PP in Patients With Ultra-low VT
Acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome with similar clinicopathological feathers caused by different etiologies.
- Conditions
- Acute Respiratory Distress Syndrome, Prone Position, Tidal Volume
- Trial name
- NCT06215209
- Testing
- position
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Southeast University, China
Obstructive Sleep Apnea
The Effect of Pure Prone Positioning Therapy for the Patients With Mild to Moderate Obstructive Sleep Apnea
Efficacy of Pure Prone Positioning (PPP) treatment in improving apnea-hypopnea index (AHI) and nocturnal oxygen saturation was investigated in mild to moderate Obstructive Sleep Apnea.
- Trial name
- NCT01368952
- Testing
- Pure prone positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Prone Positioning, High Flow Nasal Cannula
Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS
Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, China, and had subsequently spread worldwide. Twenty-nine percent of COVID-19 patients may develop ARDS.
- Conditions
- Prone Positioning, High Flow Nasal Cannula, Acute Respiratory Distress Syndrome, Corona Virus Infection
- Trial name
- NCT04325906
- Testing
- high flow nasal cannula (HFNC), Prone positioning (PP)
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Rush University Medical Center
Evaluable
Effects of Continuous Anterior Chest Compression
The aim is to test the physiological effects of continuous anterior chest compression in patients with severe to moderate ARDS.
- Trial name
- StrapVent (NCT05876468)
- Testing
- Continuous anterior chest compression
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Covid19
Effect of Prone Position onV/Q Matching in Non-intubated Patients With COVID-19
A prospective physiologic study, in participants with COVID-19-related pneumonia requiring supplemental oxygen (standard oxygen therapy or high-flow nasal cannula (HFNC)) less than 24 hours.
- Trial name
- NCT04754113
- Testing
- prone position
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Southeast University, China
Premature Infants
The Effects of Positioning After Extubation of Preterm Infants on the Respiratory Functions
The aim of this study was to examine the effect of positioning on respiratory functions of preterm infants after extubation. Hypothesis 0a (H0a): There is no difference between the oxygen saturation (SpO2) levels of preterm…
- Trial name
- NCT06352047
- Testing
- The effect of positioning on respiratory functions of preterm infants after extubation.
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
ARDS
Enteral Nutrition Delivery in Prone Position Ventilated Patients With Moderate to Severe ARDS
This pilot study is aimed to compare and assess the impact, safety, and practical utility of gastric versus postpyloric feeding in moderate to severe ARDS patients with prone position ventilation.
- Trial name
- NCT07362537
- Testing
- enteral nutrition through nasojejunal tube, enteral nutrition through nasogastric tube
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Southeast University, China
One Lung Ventilation
Comparison of Three Methods of PEEP Titration During One Lung Ventilation in Prone Position
One-lung ventilation and prone positioning during thoracoscopic esophagectomy is associated with pulmonary complications so lung protection is strongly recommended.
- Trial name
- NCT05851612
- Testing
- constant PEEP, Driving pressure guided PEEP, oxygenation method guided PEEP
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Mansoura University
Postoperative Atelectasis
Supine vs Prone Position and Atelectasis Assessed by Lung Ultrasound
Atelectasis frequently develops during and after general anesthesia due to factors such as anesthesia-induced diaphragmatic dysfunction, reduced functional residual capacity, altered ventilation-perfusion matching, and surgical…
- Trial name
- LUS-ATELEC (NCT07320092)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Breast Cancer
Two Versus One Week Breast Radiotherapy (RT)
This study is comparing two different radiation therapy approaches for early breast cancer to see which one is better for patients.
- Trial name
- PRATO (NCT06960707)
- Testing
- Radiation therapy - 1 week, Radiation therapy - 2 weeks
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- Weill Medical College of Cornell University
Inadequate or Impaired Breathing Pattern or Ventilation
Supreme LMA and Proseal LMA in Prone Anesthetized Patient
There is no significant difference about success rate of two devices.
- Trial name
- SPLMA (NCT01814306)
- Testing
- Supreme LMA, Proseal LMA
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Hemodynamic Instability
Effect of Remimazolam and Propofol on Hemodynamic Stability in Prone Position
Most of the major spinal surgeries are performed in the supine position, which causes a decrease in stroke volume and cardiac index, which leads to the occurrence of hypotension during surgery.
- Trial name
- NCT05644483
- Testing
- Remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Asan Medical Center