Clinical trials: Prone Positioning
Lung Transplant, Primary Graft Dysfunction
Primary Graft Dysfunction, Pronation, Bilateral Lung Transplants
Proning manoeuvre as an early treatment for acute severe hypoxic respiratory failure has been implemented recently during the COVID-19 pandemic.
- Trial name
- NCT06159933
- Testing
- Supine positioning, Early pronation, Late pronation
- Where
- Italy
- Volunteers
- 67 people
- Sponsor
- University of Padova
Pulmonary Atelectasis, Postoperative, Postoperative Pulmonary Complications
Ventilation Mode and Atelectasis After Prone-Position Surgery: A Lung Ultrasound Study
This prospective single-centre observational study compared two intraoperative mechanical ventilation modes, volume-controlled ventilation (VCV) and VCV with AutoFlow/AF, in adults undergoing elective surgery in the prone…
- Trial name
- VENTI-PRONE (NCT07680881)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
ARDS, Respiratory Failure
ARDS Esophageal Balloon Pressure Changes With Positioning Study
The use of esophageal balloon catheters, which use esophageal pressure as a surrogate measurement for transpleural pressure, shows promise in improving outcomes of patients with severe acute respiratory distress syndrome (ARDS)…
- Trial name
- NCT03120793
- Testing
- Esophageal balloon catheter
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of North Carolina, Chapel Hill
Lactate Blood Increase, Fluid Overload
Goal-directed Fluid Therapy in Elderly Patients Undergoing Lumbar Surgery
This is a randomized controlled clinical trial which investigates whether goal directed fluid therapy( GDT ) would show the evidence of benefit from GDT in terms of lactate kinetics then may reduce postoperative complications in…
- Conditions
- Lactate Blood Increase, Fluid Overload, Postoperative Complications
- Trial name
- NCT03974906
- Testing
- Applying goal-directed fluid therapy by continuous hemodynamic monitoring system (LiDCO）
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Peking Union Medical College Hospital
Acute Respiratory Distress Syndrome, Mechanical Ventilation Complication
Prone Positioning and Thoracoabdominal Binding on Lung and Muscle Protection in ARDS Patients During Spontaneous Breathing
Ventilator-induced diaphragmatic dysfunction and intensive care unit (ICU)-acquired weakness are two consequences of prolonged mechanical ventilation and critical illness in patients with acute respiratory distress syndrome…
- Conditions
- Acute Respiratory Distress Syndrome, Mechanical Ventilation Complication, ICU Acquired Weakness
- Trial name
- NCT05826847
- Testing
- Prone Positioning, Thoracoabdominal Binding, Control
- Where
- Chile
- Volunteers
- 14 people
- Sponsor
- University of Chile
Intraoperative Hypotension, Pulmonary Complication
Perioperative Goal Directed Therapy (PGDT) in Spinal Surgery in the Prone Position
This study aims at evaluating if a specific protocol, that can be framed in the innovative concept of Perioperative Goal Directed Therapy (PGDT), based on the evaluation of the Stroke Volume Variation (SVV) - a parameter deriving…
- Conditions
- Intraoperative Hypotension, Pulmonary Complication, Cardiovascular Complication
- Trial name
- PGDT (NCT04025086)
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- University of Catania
Acute Respiratory Failure
A Prospective Observational Cohort Study of Awake Prone Position Ventilation Strategy in Patients With Acute Respiratory Failure
Awake prone positioning has been used widely for patients with COVID-19.Many research results are not uniform on the key issue of whether the prognosis of patients can be improved，and most of the subjects were patients with…
- Trial name
- NCT05570903
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
ARDS, Acute Respiratory Distress Syndrome
Effect of Prone Positioning on Mortality in Patients With Mild to Moderate Acute Respiratory Distress Syndrome.
Acute respiratory distress syndrome (ARDS) accounts for almost 10% of intensive care units (ICU) admissions. Three ARDS stages have been defined, based on the PaO2/FIO2 ratio measured with positive end-expiratory pressure (PEEP)…
- Conditions
- ARDS, Acute Respiratory Distress Syndrome, Intensive Care Unit, Mechanical Ventilation
- Trial name
- PROMILD (NCT05056090)
- Testing
- Patients will receive MV in PP
- Where
- France
- Volunteers
- 656 people
- Sponsor
- University Hospital, Grenoble
Atelectases, Postoperative Pulmonary, Prone Position
ORI-Guided FiO₂ Titration in Prone Spine Surgery: Impact on Postoperative Atelectasis Assessed by Lung Ultrasound
Atelectasis is a frequent pulmonary complication after general anesthesia, often triggered by preoxygenation and intraoperative hyperoxia.
- Conditions
- Atelectases, Postoperative Pulmonary, Prone Position, Spine Surgery, Lung Ultrasound
- Trial name
- NCT07375173
- Testing
- Titrated Oxygen, Fixed oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Etlik City Hospital
Prone Position, Coronavirus Disease 2019
Awake Prone Positioning for Non-intubated COVID-19 Patients
The burden of coronavirus disease 2019 (COVID-19) pandemic is still on a rising course making a great stress on medical resources throughout the world.
- Conditions
- Prone Position, Coronavirus Disease 2019, Oxygenation
- Trial name
- NCT04760561
- Testing
- prone position group
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Damanhour University
COVID-19
Comparison of 2 Ventilatory Support Strategies During Coronavirus Disease 2019 (Covid-19) Pneumonia
This retrospective monocentric study compares 2 ventilatory support strategies on outcomes (length of stay, intubation, mortality) in patients admitted in Intensive Care Unit with Covid-19 related pneumonia : invasive strategy…
- Trial name
- STRATIC (NCT04799691)
- Testing
- Invasive ventilation strategy, Non-invasive ventilation strategies
- Where
- France
- Volunteers
- 133 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
CHD, Heart Defects, Congenital
The Effects of Different Prone Positioning Angles on Cardiopulmonary Function in Children After Congenital Heart Disease Surgery: A Randomized Controlled Trial
The goal of this randomized controlled trial is to learn if different head-elevated prone positioning angles can optimize cardiopulmonary function and enteral nutrition tolerance in infants and children after congenital heart…
- Conditions
- CHD, Heart Defects, Congenital, Hypoxia, Respiratory Insufficiency
- Trial name
- PACE-CHD (NCT07323979)
- Testing
- 10° Head-Elevated Prone Positioning, 30° Head-Elevated Prone Positioning, 45° Head-Elevated Prone Positioning
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Guangdong Provincial People's Hospital
Thoracic Epidural Injection
Comparison of Thoracic Epidural Pressure in the Prone and Lateral Decubitus Position
It is reported that the distribution of contrast medium had an obvious correlation with the extent of sensory analgesia after injection of LA. Our previous study showed that different posture (prone vs.
- Trial name
- NCT03128788
- Testing
- thoracic epidural catheterization
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Keimyung University Dongsan Medical Center
Pediatric ALL
Prone Fluid Responsiveness in Children
In pediatric patients in the prone position, the reliability of pulse pressure variation and stroke volume variation, and pleth variability index to predict fluid responsiveness have not previously been established.
- Trial name
- NCT05449886
- Testing
- TVC
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Optic Nerve Sheath Diameter
Optic Nerve Sheath Diameter in Craniosynostosis
Changes of optic nerve sheath diameter after position changes
- Trial name
- ONSD (NCT03131245)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Cerebral Lesion
Internal Carotid Artery Blood Flow in Infants With Prone Position
Little is known about how implementation of prone position contributes to general anesthesia-induced decrease in cerebral blood flow in infants.
- Trial name
- NCT05391282
- Testing
- ultrasound assessment
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Pressure Injury
Decreasing Intraoperative Skin Damage in Prone Position Surgeries
Preventing Pressure Injuries among patients undergoing spinal or orthopedic surgery in the prone position is challenging because of position required for surgical access and limited availability of pressure reduction surfaces for…
- Trial name
- P3I (NCT04884737)
- Testing
- Mepilex Border Flex® (MBF) dressing
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- University of California, Los Angeles
COVID-19 Acute Respiratory Distress Syndrome, COVID-19 Pneumonia
Effect of Prone Positioning on the Severity of COVID-19 Pneumonia and Acute Respiratory Distress Syndrome.
With this research, we are aiming at finding out the effectiveness of prone positioning in this region population affected by moderate pneumonia due to covid 19 infection so that the hospital staff and doctors may be encouraged…
- Conditions
- COVID-19 Acute Respiratory Distress Syndrome, COVID-19 Pneumonia, Prone Positioning
- Trial name
- COVID-19 (NCT05405335)
- Testing
- Prone Positioning Maneuver
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Ayub Medical College, Abbottabad
Nephrolithiasis, Anesthesia, Local
Over 2000 Epidural Anesthesias for Percutaneous Nephrolithotomy - a Retrospective Analysis
Percutaneous nephrolithotomy (PNL) is a renal lithiasis treatment. It is usually two staged: it begins in the lithotomy position for ureteral catheter placement and retrograde pyelography and, subsequently, an optimal renal…
- Trial name
- NCT02986997
- Where
- Poland
- Volunteers
- 2,000 people
- Sponsor
- Medical University of Warsaw
Cerebral Hypoxia During and/or Resulting From A Procedure
The Effects of Body Mass İndex On İntraabdominal Pressure And Regional Cerebral Oxygen Saturation İn Prone Position
A total of 40 ASA (American Society of Anesthesiology) physical status I-III who underwent lumbar disc hernia repair for one or two levels were included in this prospective study.
- Trial name
- NCT05392478
- Volunteers
- 40 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital