Clinical trials: Propofol Adverse Reaction
Adverse Reaction to Drug, Neonatal Disorder
Exploratory Propofol Dose Finding Study In Neonates
The aim of the study is to explore the optimal propofol dose in neonates receiving a single intravenous propofol bolus for endotracheal intubation during (semi-)elective INSURE (intubation-surfactant-extubation) procedure…
- Trial name
- NEOPROP (NCT01621373)
- Testing
- propofol administration
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sedative Adverse Reaction, Sedation Complication
Vasopressor Requirements Depends on Sedation Strategy
Most of the patients after cardiac surgery need sedation in the iCU. Sedation strategy could impact the incidence of vasopressor use.
- Conditions
- Sedative Adverse Reaction, Sedation Complication, Hemodynamic Instability, Agitation on Recovery From Sedation
- Trial name
- NCT05451381
- Testing
- Propofol, Dexmedetomidine, Dexmedetomidine and Propofol
- Where
- Ukraine
- Volunteers
- 356 people
- Sponsor
- Anesthesia Research Group UA
Propofol Adverse Reaction
Propofol Induction Based on Lean Body Weight on the Depth of Anesthesia
Propofol has significant hemodynamic side effects. It is a lipophilic agent and is generally used at a dose of 2-2.5 mg/kg for induction.
- Trial name
- propofol (NCT06862349)
- Testing
- Group T received propofol at a dose of 2-2.5 mg/kg based on total body weight, Group L received propofol at 2-2,5mg/kg dose based on lean body weight, which was calculated from CT imaging by a radiologist.
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
General Anesthetic Drug Overdose, Adverse Effect of Intravenous Anesthetics, Sequela
Fully Automated Anesthesia, Analgesia and Fluid Management
Evaluate the feasibility and quality of automated anesthesia, analgesia and fluid management based on a combination of several physiological variables (bispectral index [BIS], stroke volume [SV], and stroke volume variation…
- Conditions
- General Anesthetic Drug Overdose, Adverse Effect of Intravenous Anesthetics, Sequela, Complication of Anesthesia, Drug Delivery System Malfunction
- Trial name
- NCT02886806
- Testing
- BIS XP, Covidien, Ireland, EV-1000 TM, Edwards Lifesciences, Irvine, California, USA
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- Erasme University Hospital
Injection Site Coldness, Propofol Adverse Reaction
The Effect of Body Mass Index In Relation To Menstrual Cycle Phase on Propofol Injection Pain
There are suggestions from experimental pain studies that pain perception in patients with severe obesity differs compared with individuals with lower BMI values, with a tendency for patients with severe obesity to be hypoalgesic…
- Trial name
- NCT04078087
- Testing
- Non obese, Obese.
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia; Adverse Effect, Biliary Tract Diseases
Ciprofol vs Propofol for Reducing Hypoxia Incidence in ERCP
Intravenous anesthesia has been widely used in endoscopic retrograde cholangiopancreatography (ERCP). In the past decade, many practices have been carried out under the propofol-based monitored anesthesia care without…
- Trial name
- NCT06015074
- Testing
- Propofol, Ciprofol
- Where
- China
- Volunteers
- 136 people
- Sponsor
- RenJi Hospital
Transcutaneous Electrical Nerve Stimulation, Pain
The Effect of Transcutaneous Electrical Nerve Stimulation on Pain During Propofol Injection
Propofol, an intravenous sedative agent, frequently produces pain during injection. This study was designed to investigate whether transcutaneous electrical nerve stimulation could reduce pain during propofol injection.
- Conditions
- Transcutaneous Electrical Nerve Stimulation, Pain, Propofol Adverse Reaction
- Trial name
- NCT05046054
- Testing
- transcutaneous electrical nerve stimulation
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Kyungpook National University Hospital
Pain Syndrome, Propofol Infusion Syndrome
Warm Patch Decrease Propofol Injection Pain
Propofol causes injection pain is still a common clinical unsolved problem. Mixing a small amount of lidocaine with propofol or injecting lidocaine in advance can reduce the pain caused by propofol injection.
- Conditions
- Pain Syndrome, Propofol Infusion Syndrome, Injection Site Irritation
- Trial name
- NCT04555980
- Testing
- Warming patch, Cotton patch
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First People's Hospital of Chenzhou