Clinical trials: Prostate Cancer Aggressiveness
Prostatic Neoplasms
Pre-operative PET-MR of High Risk Prostate Cancer Patients for Assessment of Cancer Aggressiveness and Lymph Node Status
Prostate cancer is the most frequent cancer in Norwegian men. For optimal treatment, accurate staging of the disease at the time point of diagnosis is important.
- Trial name
- NCT02076503
- Testing
- PET-MR 18f-FACBC, histology (gold standard)
- Where
- Norway
- Volunteers
- 28 people
- Sponsor
- St. Olavs Hospital
Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8
Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body
This phase III trial compares the effect of adding carboplatin to the standard of care chemotherapy drug cabazitaxel versus cabazitaxel alone in treating prostate cancer that keeps growing even when the amount of testosterone in…
- Trial name
- NCT06470243
- Testing
- Biospecimen Collection, Bone Scan, Cabazitaxel
- Where
- 174 sites in United States
- Volunteers
- 528 people
- Sponsor
- SWOG Cancer Research Network
BRCA-Mutated, Neuroendocrine-Differentiated Aggressive Metastatic Castration-Sensitive Prostate Cancer
Carboplatin-Enhanced Therapy in BRCA-Mutated or Neuroendocrine-Differentiated Aggressive Metastatic Castration-Sensitive Prostate Cancer
The current standard of patients with de novo metastatic hormone sensitive prostate cancer (mHSPC) is to offer androgen deprivation therapy (ADT) with androgen receptor pathway inhibitors (ARPI).
- Conditions
- BRCA-Mutated, Neuroendocrine-Differentiated Aggressive Metastatic Castration-Sensitive Prostate Cancer, Prostate Cancer
- Trial name
- CaBRA (NCT07591467)
- Testing
- Experimental
- Where
- 5 sites in France
- Volunteers
- 330 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Prostate Cancer
Biobank for African American Prostate Cancer Research in Florida
The purposes of this study are: a) to develop a statewide Biobank for prostate cancer among men of African Ancestry in Florida and; b) to examine whether smoking increases the aggressiveness of prostate cancer using several…
- Trial name
- NCT03232411
- Testing
- Questionnaires, Saliva Samples, Tumor Tissue
- Where
- United States
- Volunteers
- 592 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Prostatic Neoplasms
Aggressive Prostate Cancers in Elderly Patients
Patients aged 70 years or older had a higher possibility of high risk cancer than younger patients.
- Trial name
- NCT01347476
- Where
- South Korea
- Volunteers
- 1,333 people
- Sponsor
- Seoul National University Hospital
Prostate Cancer
Treatment of Aggressive Prostate Cancer in Real Life: Initiation, Schedule and Management of Triptorelin Treatment.
The purpose of the protocol is to describe the proportion of subjects treated continuously with triptorelin during 12 months following treatment initiation. This study will take place at 187 locations (approximately) in France.
- Trial name
- TALISMAN (NCT04593420)
- Where
- France
- Volunteers
- 817 people
- Sponsor
- Ipsen
Prostatic Neoplasm
Dietary Factors and Racial Disparities in Prostate Cancer Aggressiveness
The North Carolina-Louisiana Prostate Cancer Project is a population-based case-only study of over 2,000 men newly diagnosed with prostate cancer designed to address racial differences in prostate cancer aggressiveness and…
- Trial name
- PCaP (NCT03289130)
- Volunteers
- 2,258 people
- Sponsor
- University of South Carolina
Prostate Carcinoma
Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study
This study investigates ways to detect prostate cancer earlier in people at genetic risk for disease that forms, grows, or spreads quickly (aggressive).
- Trial name
- NCT04472338
- Testing
- Biospecimen Collection, Laboratory Biomarker Analysis, Quality-of-Life Assessment
- Where
- 8 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Washington