Clinical trials: Prostate Cancer Detection
Prostate Cancer
Using PSMA PET-CT as a Diagnostic Tool for Detection of Prostatic Cancer at an Early Stage
The aim of the study is the evaluation of the possible role of PSMA PET-CT in early detection of prostate cancer, reducing rate of unnecessary prostate biopsies, and in cases of prostate cancer, correct staging of the disease and…
- Trial name
- NCT04116086
- Testing
- Prostate Biopsy Test
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Prostatic Cancer, Castration-Resistant
Treatment With Darolutamide +/- Radiation Therapy for Patients With a Castration Resistant Cancer and Metastases Detected by Functional Imaging
In earlier stages of prostate cancer, male sexual hormones (androgens) stimulate the growth of cancer cells. Castration-resistant prostate cancer (CRPC) means that the prostate cancer continued to grow despite patients are taking…
- Trial name
- PEACE8 (NCT06276465)
- Testing
- Darolutamide 300 mg, Stereotactic body radiation therapy, Androgen deprivation therapy
- Where
- 4 sites in France
- Volunteers
- 336 people
- Sponsor
- UNICANCER
Prostate Cancer
Cognitive and Fusion Prostatic Biopsy
The goal of this study is to compare two different prostate biopsy techniques used to detect prostate cancer. These techniques are cognitive-targeted biopsy (CTB) and magnetic resonance imaging-ultrasound fusion-targeted…
- Trial name
- CTB-FTB (NCT07306741)
- Testing
- Cognitive-targeted prostate biopsy
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Menoufia University
Prostate Cancer
Detection of Lymphnodes Using ICG During RARP
The purpose of this study is to investigate, whether the detection of lymph nodes by means of intraoperative fluorescence lymphography as part of lymphadenectomy in robot-assisted radical prostatectomy is higher than without the…
- Trial name
- NCT02163083
- Testing
- ICG
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- St. Antonius Hospital Gronau
Prostate Cancer
Threedimensional Multiparametric Ultrasound for Prostate Cancer Detection
Rationale: Current imaging techniques for the detection and grading of prostate cancer are imperfect, leading to unnecessary biopsies, suboptimal treatment decisions and missed clinically significant cancers.
- Trial name
- 3DmpUS for PCa (NCT04605276)
- Testing
- No intervention
- Where
- 3 sites in Netherlands
- Volunteers
- 608 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Breast Cancer, Cervical Cancer
EF5 Prior to Surgery or Biopsy in Patients With Breast, Prostate, or Cervical Cancer or High Grade Soft Tissue Sarcoma
RATIONALE: EF5 may detect the presence of oxygen in tumor cells and help plan effective cancer treatment. PURPOSE: Phase I trial to study the effectiveness of EF5 in detecting the presence of oxygen in tumor cells of patients who…
- Conditions
- Breast Cancer, Cervical Cancer, Head and Neck Cancer, Prostate Cancer
- Trial name
- NCT00004261
- Testing
- EF5, flow cytometry, fluorescent antibody technique
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Prostate Cancer
Biparametric MRI for Detection of Significant Prostate Cancer
Our aim is to develop a new diagnostic approach to improve the diagnosis of men suspicious of having significant prostate cancer (sPCa).
- Trial name
- BIDOC (NCT02584179)
- Testing
- Biparametric MRI before biopsy
- Where
- Denmark
- Volunteers
- 1,063 people
- Sponsor
- Herlev Hospital
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Prostatic Neoplasms
Interest of Indocyanine Green in Neoplastic Prostatic Tissue
Prostate cancer, with more than 70,000 new cases and 8900 deaths a year in France, is a major public health problem. Until 28% of patients treated with surgery will present a positive surgical margin resulting in an incomplete…
- Trial name
- NCT02260349
- Testing
- indocyanine green infusion
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne