Clinical trials: Prostate Cancer Detection
Prostatic Neoplasms
PSMA-PET and MRI for Detection of Recurrent Prostate Cancer After Radical Treatment
Approximately one third of prostate cancer patients experience biochemical relapse following initial radical prostatectomy or curative radiotherapy.
- Trial name
- NCT04298112
- Testing
- PSMA PET/CT, PSMA PET/MR
- Where
- 3 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Norwegian University of Science and Technology
Prostate Cancer
Ga-68 PSMA PET/CT vs mpMRI in Cognitive Prostate Biopsy
Prostate cancer is the most common malignancy among elderly men. With the routine use of prostate-specific antigen (PSA) testing since the 1980s, the incidence of prostate cancer has significantly increased.
- Trial name
- PSMA-MRI BX (NCT07533344)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Detection and Characterization of Prostate Cancer Based on Artificial Intelligence
Automatic Detection in MRI of Prostate Cancer: DAICAP
Prostate cancer is the most common cancer in France and the 3rd most common cancer death in humans. The introduction of pre-biopsy MRI has considerably improved the quality of prostate cancer (PCa) diagnosis by increasing the…
- Trial name
- DAICAP (NCT05513820)
- Where
- France
- Volunteers
- 1,250 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prostate Cancer, Adenocarcinoma
Imperial Prostate 7 - Prostate Assessment Using Comparative Interventions - Fast Mri and Image-fusion for Cancer
To evaluate the role of biparametric MRI and image-fusion targeted biopsies for the detection of prostate cancer. To determine whether biparametric MRI (bpMRI) could be recommended as an alternative to multiparametric MRI (mpMRI)…
- Conditions
- Prostate Cancer, Adenocarcinoma, Prostatic Neoplasms, Prostatic Diseases
- Trial name
- IP7-PACIFIC (NCT05574647)
- Testing
- bpMRI, Image-Fusion targeted and systematic Biopsy
- Where
- 15 sites in United Kingdom
- Volunteers
- 3,600 people
- Sponsor
- Imperial College London
Prostate Cancer, Local Anesthesia
A Prospective Randomized Trial of Two Different Prostate Biopsy Schemes
The main purpose is to compare the detection rate of 20-core versus 12-core prostate biopsy. The secondary objective is to evaluate pain perception using a validated scale to compare the analgesia provided by the two different…
- Conditions
- Prostate Cancer, Local Anesthesia, Prostate-Specific Antigen/Blood, Biopsy/Methods
- Trial name
- NCT02825225
- Testing
- 20 core-biopsy fragments, Base and apex local anesthesia
- Where
- Brazil
- Volunteers
- 750 people
- Sponsor
- University of Nove de Julho
Prostate Carcinoma
[18F]-rhPSMA PET-CT Imaging Performance in Patients With Prostate Cancer
This clinical trial evaluates [18F]-rh PSMA positron emission tomography (PET)-computed tomography (CT) imaging performance in patients with prostate cancer.
- Trial name
- NCT06580015
- Testing
- Computed Tomography, Flotufolastat F-18 Gallium, Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- City of Hope Medical Center
Breast Cancer, Colorectal Cancer
Detection of Cancer in Breath Samples by Trained Detection Dogs
The goal of this study is to show that trained detection dogs can identify breast, lung, prostate or colorectal cancer by sniffing masks containing breath samples.
- Conditions
- Breast Cancer, Colorectal Cancer, PROSTATE CANCER, Lung Cancer
- Trial name
- NCT06255041
- Where
- 2 sites in Israel
- Volunteers
- 1,386 people, healthy volunteers welcome
- Sponsor
- SpotitEarly
Prostate Cancers
Prospective Evaluation of 68Ga-PSMA PET-CT for Recurrence Detection of Prostate Cancer and Its Impact on Patient Management
Single arm, phase II exploratory trial to prospectively evaluate the impact of 68Ga-PSMA-PET/CT on the therapeutic management of patients with biological recurrent prostate cancer and negative, equivocal or oligometastatic…
- Trial name
- ProsPERo (NCT02810886)
- Testing
- 68Ga-(HBED-CC)-PSMA
- Sponsor
- Jules Bordet Institute
Prostate Cancer, Prostate Cancer Diagnosis
Cognitive Fusion Prostate Biopsy With Biparametric Magnetic Resonance in the Detection of Prostate Cancer
The goal of this prospective observational study is to evaluate the diagnostic precision of the Biparametric Magnetic Resonance Imaging (bpMRI) in the detection of clinically significant prostate cancer (PCa) in patients with…
- Trial name
- NCT05818631
- Testing
- fusion cognitive prostate biopsy
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- José Joaquín Mira
Lung Cancer, Gastric Cancer
INSPIRE: a Multi-Cancer Early Detection Study
This research constitutes a multi-centric, case-control designed investigation aimed at developing and implementing a blinded validation of a machine learning-powered, multi-cancer early detection model.
- Conditions
- Lung Cancer, Gastric Cancer, Liver Cancer, Colorectal Cancer
- Trial name
- INSPIRE (NCT06440018)
- Where
- China
- Volunteers
- 5,350 people
- Sponsor
- Singlera Genomics Inc.
Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma
11C-YJH08 PET Imaging for Detection of Glucocorticoid Receptor Expression
This phase I trial studies if positron emission tomography (PET) imaging using 11C-YJH08 can be useful for detecting certain cell receptor expression in tumor cells in patients with cancer that has spread to other parts of the…
- Conditions
- Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8
- Trial name
- NCT04927663
- Testing
- Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Rahul Aggarwal
Prostatic Neoplasm
Detection of High Grade Prostate Cancer With Subharmonic Ultrasound Imaging, A Pilot Study
This is a phase II single center study using contrast-enhanced ultrasound to identify aggressive forms of prostate cancer with subharmonic imaging. The following are the study objectives: 1.
- Trial name
- NCT02967458
- Testing
- Perflutren Lipid Microsphere Intravenous Suspension
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Thomas Jefferson University
Prostate Cancer, Bladder Cancer
Study of Ferumoxytol Enhanced MRI for Detecting Lymph Node Metastases in Prostate, Bladder, and Kidney Cancers
Background: People with prostate, bladder, or kidney cancer often have their cancer spread (metastasize) to lymph nodes. It is important for your doctor to know if this has occurred but currently it can be hard to determine if…
- Conditions
- Prostate Cancer, Bladder Cancer, Kidney Cancer
- Trial name
- NCT02141490
- Testing
- Ferumoxytol, Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer
Transurethral Ultrasonic Imaging For Detection and Classification of Prostate Cancer
This study is being performed to verify the ability to use minimally invasive transurethral ultrasonic imaging technology for the purpose of identifying prostate cancer.
- Trial name
- NCT02307552
- Testing
- UreScan
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of California, Irvine
Glioma, Astrocytoma
Ga-68 Prostate Specific Membrane Antigen PET/CT in Gliomas
As a part of molecular imaging, many PET tracers have been investigated in this regard. Those include 18F-FDG being glucose analogue, 18F-FLT representing nucleoside metabolism, and 18F-FDOPA, 18F-FET, 11C-MET as amino acids…
- Conditions
- Glioma, Astrocytoma, Anaplastic Astrocytoma, Oligodendroglioma
- Trial name
- NCT06241391
- Testing
- PSMA PET-CT
- Where
- India
- Volunteers
- 35 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Prostate Cancer, Urine
Investigation of Urinary Biomarkers for the Detection of Prostate Cancer
The aim of this study is to investigate and possibly validate urinary biomarkers for prostate cancer. During this study the focus will be on aberrations of selected genes as prognostic or predictive value has been shown for these…
- Conditions
- Prostate Cancer, Urine, Liquid Biopsy
- Trial name
- URODETECT-WP2 (NCT05454371)
- Testing
- Colli-Pee UAS devices
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novosanis NV
Prostate Cancer
Prostate Assessment with Restriction Spectrum Imaging (RSI) MRI
This single-center study will enroll 40 male participants to complete 2 diffusion magnetic resonance images within 30 days of each other.
- Trial name
- NCT04992728
- Testing
- Restricted Spectrum Magnetic Resonance Imagining
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Diego
Prostate Cancer
Artificial Intelligence (AI)-Assisted Risk-based Prostate Cancer Detection
This is a prospective clinical study recruiting 510 men at risk of PCa to undergo urine, blood, AI-assisted ultrasound and AI-assisted MRI investigations to stratify risk of clinically significant PCa (csPCa).
- Trial name
- NCT05443412
- Testing
- Diagnostic test for prostate cancer
- Where
- Hong Kong
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Prostate Cancer
Danish Prostate Cancer Consortium Study-1
The purpose of the study is to investigate if a new promising microRNA-based urine biomarker test for prostate cancer, called uCaP, is better than the current standard test (PSA) to identify men who would benefit from an MRI scan…
- Trial name
- DPCC-1 (NCT05767307)
- Where
- 3 sites in Denmark
- Volunteers
- 2,500 people
- Sponsor
- Aarhus University Hospital
Prostate Cancer
GUidance In Prostate Cancer DEtection With 18F-PSMA-1007-PET/MRI and Targeted Biopsies
The goal of this clinical study is to test the performance of PSMA PET/MRI-guided biopsies against systematic biopsies in men with negative MRI scan (PI-RADS 1-2) of the prostate with continuous suspicion of clinically…
- Trial name
- GUIDE PSMA PET (NCT07258056)
- Testing
- PSMA-guided and systematic biopsies
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Mads Ryo Jochumsen