Clinical trials: Prostate Cancer Diagnosis
Prostate Cancer (Diagnosis)
Virtual Biopsy of Prostate Cancer Using PSMA PET and AI
Prostate cancer is the most common type of cancer in Norwegian men, but many tumors are slow-growing and do not require treatment.
- Trial name
- NCT07266129
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- University Hospital of North Norway
Benign Prostate Hypertrophy(BPH), Prostate Cancer (Diagnosis)
Application of Quantum Detection-Driven Artificial Intelligence Algorithms for Single-Molecule cfDNA Characterization in the Early Diagnosis of Prostate Cancer
This research project aims to develop a novel blood testing method integrating cutting-edge quantum sensing and artificial intelligence technologies to achieve precise, non-invasive early diagnosis of prostate cancer.
- Conditions
- Benign Prostate Hypertrophy(BPH), Prostate Cancer (Diagnosis), Prostate Neoplasm
- Trial name
- NCT07238959
- Testing
- Quantum Detection
- Where
- 7 sites in China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Prostate Cancer (Diagnosis), Prostate Cancer Patients Who Have Brachytherapy Seed Implant
Immune Biomarkers in Prostate Cancer Patients Treated With Brachytherapy
Analysis of peripheral immune cells before, during, and after brachytherapy treatment. Corresponding analysis of tissue samples collected during brachytherapy treatment.
- Conditions
- Prostate Cancer (Diagnosis), Prostate Cancer Patients Who Have Brachytherapy Seed Implant, Prostate Cancer Patients Treated by Radiotherapy, Prostate Cancer Recurrent
- Trial name
- NCT07131956
- Where
- 3 sites in Germany
- Volunteers
- 200 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Breast Cancer, Lung Cancer (Diagnosis)
Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots
To evaluate a community-based outreach initiative for screening, diagnosis, and treatment of breast, lung, and prostate cancers in underserved adults using the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM)…
- Conditions
- Breast Cancer, Lung Cancer (Diagnosis), Prostate Cancer
- Trial name
- NCT07231159
- Testing
- referral for definitive diagnosis based on their cancer screening results, Engagement
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Prostate Cancer, Diagnosis
Fusion or Cognitive Ultrasound-guided Biopsy to Detect Prostate Cancer
The MRI-targeted biopsy for prostate cancer detection can be performed using one of two techniques: 1. Software-based fusion of MRI and ultrasound images (software fusion) or 2.
- Trial name
- FOCUS-PC (NCT06517901)
- Testing
- Software fusion prostate biopsy, Cognitive fusion prostate biopsy
- Where
- 4 sites in United States, Canada
- Volunteers
- 1,306 people
- Sponsor
- Albany Medical College
Prostate Cancer (Diagnosis)
Prehabilitation to Patients With Prostate Cancer
The goal of this feasibility study is to test a newly developed, multicomponent prehabilitation intervention to patients with prostate cancer, to improve their resilience to treatment side-effects.
- Trial name
- PREPP (NCT07162987)
- Testing
- Prehabilitation
- Where
- 3 sites in Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Prostate Carcinoma, MRI
Exploring the Correlation Between MRI Image Characteristics and Diagnosis, Pathology and Prognosis in Patients With Prostate Lesions
Globally, prostate cancer is the second most common malignant tumor and the fifth leading cause of cancer-related death in men. In China, there will be more than 125,000 new cases of prostate cancer in 2022, ranking sixth in the…
- Conditions
- Prostate Carcinoma, MRI, Diagnosis
- Trial name
- NCT06946771
- Testing
- Advanced MRI parameters for the diagnosis of prostate cancer
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Zhen Li
Prostate Cancer (Diagnosis), Prostate-specific Membrane Antigen
Intratumoral Heterogeneity on [18F]PSMA and [18F]FDG PET/CT in Predicting Invasion and Prognosis of Prostate Cancer
The purpose of this study is to analyze heterogeneity of prostate cancer（PCa）based on the head-to-head imaging of prostate-specific membrane antigen (PSMA) and fluorodeoxyglucose (FDG) positron emission tomography computed…
- Conditions
- Prostate Cancer (Diagnosis), Prostate-specific Membrane Antigen, Positron Emission Tomography (PET)
- Trial name
- NCT06919159
- Testing
- PSMA PET/CT scan, FDG-PET
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Jiequn Yu
Prostate Cancer Diagnosis
Can Needle Size Improve Cancer Detection Rate of Transperineal MRI Target Prostate Biopsy Without Affecting Side Effects?
Differences in terms of diagnostic capability and side effects related to the needle caliber used for prostate biopsy sampling in patients with suspected prostate cancer
- Trial name
- TARGET (NCT06420115)
- Testing
- different needle size for prostate biopsy
- Where
- Italy
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
68Ga-PSMA PET/CT Guided Prostate Biopsy, Mp-3TMRI Guided Prostate Biopsy
Mp-3TMRI and 68Ga-PSMA PET/CT Guided Prostate Biopsy and Tumor Node Metastasis (TNM) Staging.
BIOPSTAGE is a prospective, non-randomized, diagnostic, multi-cohort investigational study to evaluate the impact of pelvic Multi-parametric 3-Tesla magnetic resonance imaging (mp-3TMRI) and whole-body 68Ga-PSMA PET/CT for…
- Conditions
- 68Ga-PSMA PET/CT Guided Prostate Biopsy, Mp-3TMRI Guided Prostate Biopsy, Prostate Cancer, TNM Staging
- Trial name
- BIOPSTAGE (NCT03465579)
- Testing
- pelvic MRI, 68Ga-PSMA PET/CT
- Where
- 2 sites in Italy
- Volunteers
- 261 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Prostate Cancer Diagnosis
PROVIZ - a Machine Learning Software, to Support Targeting of Prostate Biopsies on MR Images in Biopsy-naive Patients
To perform a traditional feasibility clinical investigation, as defined in ISO 14155:2020, to investigate preliminary feasibility, safety, and clinical performance information of a near-final design of the investigational…
- Trial name
- NCT06000046
- Testing
- Automatic image analysis
- Where
- Norway
- Volunteers
- 82 people
- Sponsor
- Norwegian University of Science and Technology
Prostate Cancer (Diagnosis)
Stockholm3 Validation Study in a Multi-Ethnic Cohort
Introduction: Prostate cancer (PCa) is the most commonly detected cancer in men and is the second leading cause of cancer death.
- Trial name
- SEPTA (NCT04583072)
- Testing
- The Stockholm3 test
- Where
- 14 sites in United States, Canada
- Volunteers
- 2,152 people
- Sponsor
- Karolinska Institutet
the Application of Artificial Intelligence in the Diagnosis of Prostate Cancer
Artificial Intelligence-Based Computer-Aided Diagnosis of Prostate Cancer
One-fifth of all men will develop clinically significant prostate cancers (CsPC) in their lifetime. An estimated 268,490 new prostate cancer (PCa) cases and 34,500 deaths are expected in the United States during the year 2022…
- Trial name
- NCT05513638
- Testing
- the clinical use of artificial intelligence in the diagnosis of prostate cancer
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Prostate Cancer (Diagnosis)
Evaluation of Length and Quality of Prostate Biopsies Taken by a New Biopsy Needle
Patient-blinded randomized controlled trial evaluating length and quality of prostate biopsies taken by a novel biopsy needle.
- Trial name
- NCT04880681
- Testing
- Novel needle (18 G, 25 cm with 19 mm sample notch) in a new actuator., Standard Tru Cut biopsy needle (Argon 18G, 25 cm biopsy needle with a 19 mm sample notch) in a standard actuator (Möller Medical Blue RBG-1000-10-1000)
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Prostate Cancer, Prostate Cancer Diagnosis
Cognitive Fusion Prostate Biopsy With Biparametric Magnetic Resonance in the Detection of Prostate Cancer
The goal of this prospective observational study is to evaluate the diagnostic precision of the Biparametric Magnetic Resonance Imaging (bpMRI) in the detection of clinically significant prostate cancer (PCa) in patients with…
- Trial name
- NCT05818631
- Testing
- fusion cognitive prostate biopsy
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- José Joaquín Mira
Prostate Cancer Diagnosis
PSMA PET Scan and mpMRI for Prostate Cancer Detection
Prospective, randomized, phase 2 clinical trial to determine if PSMA PET imaging plus mpMRI improves detection of clinically significant prostate cancer as compared to mpMRI alone.
- Trial name
- NCT05820724
- Testing
- PSMA PET scan, No PSMA PET, 18F- DCFPyl Injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Prostate Cancer (Diagnosis)
Prostate Cancer Secondary Screening in Sapienza and Policlinico Umberto I
Prostate Cancer (PCa) screening is still a controversial topic in the urology community, this is mostly linked to the low specificity of Prostate Specific Antigen (PSA) value.
- Trial name
- ProSa-I (NCT04803188)
- Testing
- Magnetic Resonance
- Where
- Italy
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Prostate Cancer (Diagnosis)
New Biopsy Needle - Evaluation of Prostate Biopsy Quality
Patient blinded randomized prospective trial evaluating prostate biopsy quality of a novel biopsy needle.
- Trial name
- NCT04091230
- Testing
- TRUSbx
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Region Skane
Prostate Cancer (Diagnosis)
Predicting Prostate Cancer in Elderly Men
We aim to analyze whether the "liquid biopsy" model could increase the specificity of detecting men with an aggressive (defined as Gleason score ≥ 7) prostate cancer and thereby reduce the proportion of men who undergo prostate…
- Trial name
- NCT04079699
- Testing
- Liquid Biopsy, Standard biopsy
- Volunteers
- 700 people
- Sponsor
- Odense University Hospital
Cellular Diagnosis, Prostate Cancer
ClariCore Optical Biopsy System Used in TRUS (Trans-Rectal Ultrasound)-Guided Prostrate Biopsy
The purpose of the study is to collect information on prostrate biopsy tissue for use in developing a method determining the difference in normal and cancerous prostrate tissue using the ClariCore System.
- Trial name
- NCT02928640
- Testing
- ClariCore System
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Precision Biopsy, Inc.