Clinical trials: Prostate Carcinoma
Prostate Cancer
AGN-Cogni.Q Acute Dose Safety and Pharmacokinetics Dose-Response in Prostate Cancer Patients
This study is to obtain acute dose safety and pharmacokinetics/pharmacodynamics (PK/PD) data in a dose-response trial in prostate cancer patients.
- Trial name
- NCT05375539
- Testing
- AGN-Cogni.Q
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Milton S. Hershey Medical Center
Prostate Cancer
Radiotherapy to the Prostate and Dominant Intra-Prostatic Lesion (DIL)
The purpose of the study is to find out the feasibility and effects of ultra-hypofractionated radiotherapy to the prostate and dominant lesion as definitive treatment for intermediate risk prostrate cancer.
- Trial name
- NCT03269422
- Testing
- MR-based image-guided, intensity-modulated radiotherapy
- Where
- 7 sites in United States
- Volunteers
- 35 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer, Prostate Adenocarcinoma
Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer
This is a prospective, open-label Phase 3 study to evaluate copper Cu 64 PSMA I\&T injection for PET/CT imaging in patients with newly diagnosed unfavorable intermediate high-risk, high-risk or very high-risk prostate cancer.
- Trial name
- Solar-Stage (NCT06235151)
- Testing
- Copper Cu 64 PSMA I&T
- Where
- 43 sites in United States
- Volunteers
- 439 people
- Sponsor
- Curium US LLC
Metastatic Prostate Cancer, Prostate Cancer
[18F]Fluorthanatrace - Positron Emission Tomography (FTT-PET) and ctDNA to Predict Response to PARP Inhibitor Therapy in Metastatic Prostate Cancer (mPC)
This multicenter center, open-label, baseline-controlled diagnostic imaging study designed to assess the use of Fluorthanatrace-Positron Emission tomography (FTT-PET) as a PARP inhibitor (PARPi) therapy predictive imaging…
- Trial name
- NCT07723651
- Testing
- 1-(4-(2-Fluoroethoxy)phenyl)-8,9-dihiydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one, FTT-PET/CT, EnhanceAR-Seq
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- Washington University School of Medicine
Prostate Cancer
Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy
RATIONALE: Androgens can cause the growth of prostate cancer cells. Drugs, such as ketoconazole, may stop the adrenal glands from making androgens.
- Trial name
- NCT00460031
- Testing
- ketoconazole, lenalidomide, therapeutic hydrocortisone
- Where
- 6 sites in United States
- Volunteers
- 34 people
- Sponsor
- Case Comprehensive Cancer Center
Prostate Cancer
A Study of Leuprolide to Treat Prostate Cancer
To assess the efficacy and safety of 2 new formulations of leuprolide acetate 45 mg 6-month depot, Formulation A or Formulation B, for the treatment of patients with prostate cancer.
- Trial name
- NCT00626431
- Testing
- Leuprolide acetate - Formulation A, Leuprolide acetate - Formulation B
- Where
- 63 sites in United States
- Volunteers
- 310 people
- Sponsor
- Abbott
Breast Cancer, Colorectal Cancer
Ambulatory Cancer Pain Management: A Feasibility Study
The primary purpose of this study is to examine the feasibility of collecting pain and other symptom data in outpatient treatment centers across multiple institutions in the Texas Medical Center (TMC).
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT00507351
- Testing
- Questionnaire
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer
Safety and Efficacy of Irreversible Electroporation in Ablation of Prostate Cancer in Humans
Up to 16 patients with confirmed low- or intermediate risk prostate cancer scheduled for a radical prostatectomy will be asked to have the Irreversible Electroporation (IRE) procedure approximately 30 days prior to the…
- Trial name
- NCT01790451
- Testing
- Irreversible Electroporation
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Clinical Research Office of the Endourological Society
Prostate Carcinoma
Systemic Light Exposure in Preventing Frailty in Older Patients With Prostate Cancer on Hormonal Therapy
This pilot trial studies how well systemic light exposure works in preventing frailty in older patients with prostate cancer on hormonal therapy.
- Trial name
- NCT03661437
- Testing
- Actigraph, Questionnaire Administration, Systematic Light Exposure
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- City of Hope Medical Center
Prostate Cancer
Evaluation of Knowledge and Practice About Prostate Cancer in Male Employees
Analyze, through an online questionnaire, the knowledge and practice about the prevention and detection of prostate cancer in male employees of a pharmaceutical company.
- Trial name
- LB2008 (NCT05040672)
- Testing
- questionare online application
- Where
- Brazil
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Libbs Farmacêutica LTDA
Breast Cancer, Colorectal Cancer
Bortezomib and Gemcitabine in Treating Older Patients With Advanced Solid Tumors
RATIONALE: Bortezomib may stop the growth of solid tumors by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Conditions
- Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Kidney Cancer
- Trial name
- NCT00620295
- Testing
- bortezomib, gemcitabine hydrochloride
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Prostate Cancer
MRI Targeted Focal Laser Thermal Therapy of Biopsy Confirmed Prostate Cancer
The objective of this study is to establish the safety of MRI targeted laser thermal treatment for men with biopsy confirmed early stage low grade single sector prostate cancer.
- Trial name
- NCT00448695
- Testing
- MRI Targeted Focal Thermal Therapy of Prostate Cancer
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto
MRI Scan
Evaluation of a Targeted Magnetic Resonance Imaging Contrast Agent in Prostate Cancer Patients
This phase 1b open label, dose-escalating investigation study is to evaluate the dose dependent initial efficacy of the use of MT218 injection for biomarker targeted MR molecular imaging (MRMI) of prostate cancer in patients…
- Trial name
- NCT06262139
- Testing
- MT218 injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Songqi Gao
Prostate Cancer
Prostate Cancer Detection Using the Stockholm3 Test and MR/Fusion Biopsies
The STHLM3-MRI trial is a study comparing traditional prostate cancer detection using PSA and systematic biopsies with the improved pipeline for prostate cancer detection using the STHLM3 test and targeted biopsies in a screening…
- Trial name
- STHLM3MR-2 (NCT03377881)
- Testing
- MRI/Fusion biopsies, Systematic biopsies
- Where
- 3 sites in Sweden
- Volunteers
- 12,750 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Prostate Carcinosarcoma
microRNA Profiles Identification in Adeno Carcinoma Prostate Cancer
In our study, the investigators want to find correlation between circulating miRNAs associated with prostate cancer metastases to bones and to lymph nodes separately with results of 68Ga-PSMA ligand PET (positron emission…
- Trial name
- NCT02964351
- Testing
- High PSA levels
- Volunteers
- 120 people
- Sponsor
- Assuta Medical Center
Adenocarcinoma of the Prostate, Stage I Prostate Cancer
Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer
This randomized phase II trial will evaluate if a low omega-6, high omega-3 fat diet combined with fish oil has the potential to delay disease progression in patients with prostate cancer undergoing active surveillance.
- Conditions
- Adenocarcinoma of the Prostate, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
- Trial name
- NCT02176902
- Testing
- behavioral dietary intervention, omega-3 fatty acid, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostatic Neoplasms
Verification of Shear Wave Elastography for DEtection of Prostate Cancer
1. Objective To provide evidence that adding shear wave elastography during sono-guided prostate biopsy can increase prostate cancer detection rate and to demonstrate that shear wave elastography of the prostate can discriminate…
- Trial name
- NCT04836949
- Testing
- Shear Wave Elastography of prostate, Conventional Prostate Ultrasound
- Where
- South Korea
- Volunteers
- 170 people
- Sponsor
- Yonsei University
Prostate Cancer
IG-VMAT for Localized Prostate Cancer
To determine if hypofractionated IG-VMAT (70 Gy in 28 fractions over 5.6 weeks) will result in disease-free survival (DFS) that is no worse than DFS following conventionally fractionated IG-VMAT (80Gy in 40 fractions over 8…
- Trial name
- NCT02934685
- Testing
- hypofraction, convention
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Hospital
Prostate Cancer
FACBC PET/CT for Recurrent Prostate Cancer
Hypothesis:Anti-[18F]FACBC PET-CT will adequately detect local and extraprostatic recurrence, and lead to better characterization of disease status in restaging patients.
- Trial name
- NCT00562315
- Testing
- FACBC, ProstaScinct
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- David M. Schuster, MD
Prostatic Cancer, Prostatic Neoplasm
Open Anterograde Radical Prostatectomy Compared to Open Retrograde Technique
Prospective randomized study performing open anterograde anatomical radical retropubic prostatectomy (RRP2A) using the same technique of minimally invasive surgery described by the Pasadena consensus for the procedure assisted by…
- Trial name
- RRP2A (NCT02687308)
- Testing
- 1 Retrograde radical prostatectomy RRP, 2 Anterograde radical prostatectomy RRP2A
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Rio de Janeiro State University