Clinical trials: Prostate Disease
Prostate Cancer
Prostate Cancer Treatment Following Radiation Failure With High Intensity Focused Ultrasound (HIFU)
This is a feasibility study to determine safety and the ability of HIFU (High Intensity Focused Ultrasound)to selectively destroy prostate cancer tissue in men who demonstrate local recurrence of prostate cancer following…
- Trial name
- NCT00318240
- Testing
- High Intensity Focused Ultrasound
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Prostate Cancer
Assessment of New Molecular Imaging Strategies for Prostate Cancer
In this study 30 men, with advanced metastatic Castration-Resistant Prostate Cancer (CRPC) planned to have hormonal treatment, will undergo conventional imaging and functional imaging prior to treatment and post treatment to…
- Trial name
- MISTER (NCT02813226)
- Testing
- Molecular Imaging
- Where
- 3 sites in Canada
- Volunteers
- 36 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Prostate Cancer, Stereotactic Body Radiation Therapy
START-MET HS Prostate Cancer. : SbrT & Androgen Receptor Therapy METastatic HSPC
Phase III study of stereotactic body radiation therapy (SBRT) plus standard of care in castration sensitive oligometastatic prostate cancer patients, defined as androgen deprivation therapy plus radiotherapy to the primary tumor…
- Trial name
- START-MET (NCT05209243)
- Testing
- SBRT, STANDARD OF CARE
- Where
- 2 sites in Spain
- Volunteers
- 266 people
- Sponsor
- Instituto de Investigación en Oncología Radioterápica - Fundación Española de Oncología Radioterápic
Prostate Cancer
Prostate SABR With Intra-Prostatic SABR Boost
Stereotactic Ablative Radiation (SABR/SBRT) will be prescribed to a dose of 35 Gy in 5 fractions, once weekly to prostate with a simultaneous intra-prostatic boost to the MR detected nodule up to 50Gy.
- Trial name
- NCT04212715
- Testing
- Pelvic SABR with intra-prostatic SABR
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- King Saud University
Prostate Cancer, Prostatic Neoplasms
Multiparametric Ultrasound Imaging in Prostate Cancer
Rationale: The current limitations in prostate cancer diagnostics, due to lack of accuracy of the available techniques, lead to over- and undertreatment for a significant fraction of patients with prostate cancer.
- Trial name
- NCT03101176
- Testing
- SonoVue
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Adrenocortical Carcinoma, Breast Cancer
Combination Chemotherapy With Suramin Plus Doxorubicin in Treating Patients With Advanced Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Conditions
- Adrenocortical Carcinoma, Breast Cancer, Colorectal Cancer, Prostate Cancer
- Trial name
- NCT00003038
- Testing
- doxorubicin hydrochloride, suramin
- Where
- United States
- Sponsor
- Mayo Clinic
Glioblastoma, Esophageal Cancer
Serial MRI Scans During Radiation Therapy
This is a phase 1 study to determine the feasibility and utility of using serial magnetic resonance imaging (MRI) to assess treatment response during and after radiation therapy (standard of care cancer treatment) for…
- Conditions
- Glioblastoma, Esophageal Cancer, Radiotherapy, Magnetic Resonance Imaging
- Trial name
- RELAY (NCT04188535)
- Testing
- MRI IMAGING
- Where
- 2 sites in United States
- Volunteers
- 149 people
- Sponsor
- Dana-Farber Cancer Institute
Prostate Cancer Aggressiveness
Active Surveillance SNEP Assay Registry Trial for Prostate Cancer
A multi-center, prospective active surveillance registry trial assessing the performance of a non-invasive blood test for indolent prostate cancer disease management.
- Trial name
- NCT04052048
- Testing
- Subtraction Normalized Expression of Phagocytes Blood Test
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Immunis.AI
Prostate Cancer
The Effect of ADT on PSMA-PET.
Phase A: To describe and to determine the maximum standardised uptake values (SUV) in prostate specific membrane antigen positron emission tomography (PSMA-PET) before ADT and 7, 14 and 28 days after ADT.
- Trial name
- ADTPSMA (NCT03313726)
- Testing
- GnRH antagonist
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Turku University Hospital
Metastatic Prostate Cancer
Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer
This study will evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of AZD5305 when given in combination with new hormonal agents (NHAs) in patients with Metastatic Prostate Cancer.
- Trial name
- PETRANHA (NCT05367440)
- Testing
- AZD5305, Enzalutamide, Abiraterone Acetate
- Where
- 20 sites in United States, Australia and 2 more
- Volunteers
- 174 people
- Sponsor
- AstraZeneca
Prostate Cancer
Extension Study Investigating the Long-Term Safety and Tolerability of Repeat Doses of FE200486 in Prostate Cancer Patients
An Open-Label, Multi-Center, Extension Study Investigating the Long-Term Safety and Tolerability of Repeat Doses of FE200486 in Prostate Cancer Patients
- Trial name
- NCT00215657
- Testing
- Degarelix
- Volunteers
- 131 people
- Sponsor
- Ferring Pharmaceuticals
Prostatic Neoplasms, Castration-Resistant
Survival Outcomes in Metastatic Prostate Cancer in the Brazilian Population - Analysis of Individual Characteristics and Treatment Modalities in Different National Health Institutions.
Survival outcomes in metastatic prostate cancer in the population Brazilian - analysis of individual characteristics and modalities of treatment in different national health institutions
- Trial name
- LACOG 1818 (NCT04962919)
- Where
- 18 sites in Brazil
- Volunteers
- 584 people
- Sponsor
- Latin American Cooperative Oncology Group
Prostate Adenocarcinoma
Expanded Access to Gallium-68 PSMA-11 PET in Patients With Biochemical Recurrent Prostate Cancer
This is an expanded access program using 68Ga PSMA-HBED-CC (68Ga-PSMA-11). The primary goal of this expanded access program is to make 68Ga PSMA-11 PET/CT imaging available to patients.
- Trial name
- NCT05415228
- Testing
- 68Ga-PSMA-11
- Sponsor
- Morand Piert, MD
Prostate Cancer
PRISMA-PET - Primary Staging of Prostate Cancer With PSMA
Early and correct diagnostic staging is paramount to keep patients with newly diagnosed prostate cancer in the correct treatment tract to avoid under- and overdiagnosis in prostate cancer staging.
- Trial name
- NCT05123300
- Testing
- 18F-PSMA-1007
- Where
- 3 sites in Denmark
- Volunteers
- 385 people
- Sponsor
- Odense University Hospital
Prostate Cancer
Adjuvant Docetaxel and Estramustine Phosphate for High Risk Localized Prostate Cancer
This trial will evaluate the feasibility, toxicity, and efficacy of docetaxel/estramustine, as in the adjuvant therapy of patients with high-risk prostate cancer after definitive local therapy.
- Trial name
- NCT00193271
- Testing
- Docetaxel, Estramustine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- SCRI Development Innovations, LLC
Obesity, Prostate Cancer
Weight Management Aimed to Reduce Risk and Improve Outcomes From Radical Prostatectomy
The purpose of this study is to test how a weight management program affects substances in the blood called biomarkers that can show the presence or severity of cancer, compared to a standardized diet and exercise educational…
- Trial name
- WARRIOR (NCT03261271)
- Testing
- Weight Loss Program, Standardized educational flyer, Weight Maintenance Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kansas Medical Center
Prostate Cancer
HDR Focal: Feasibility Study
Brachytherapy as a monotherapy treatment is highly effective for localized prostate cancer, traditionally being delivered to the whole prostate gland.
- Trial name
- NCT02918253
- Testing
- targeted focal HDR brachytherapy, Whole-gland HDR Brachytherapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Benign Prostatic Hyperplasia (BPH)
Study of Median Lobe Prostatic UroLift Procedure
The purpose of this study is to evaluate the safety and effectiveness of using UroLift in subjects with a prostatic median lobe enlargement due to benign prostatic hyperplasia (BPH).
- Trial name
- NCT02625545
- Testing
- UroLift System procedure
- Volunteers
- 45 people
- Sponsor
- NeoTract, Inc.
Primary Malignant Neoplasm of Prostate (Diagnosis)
MRI-Guided Cryoablation for Focal Native Prostate Cancer
The purpose of this research is to collect data about the MRI cryoablation procedure your doctor(s) would normally perform in order to treat the participants focal prostate cancer and to evaluate the participants condition after…
- Trial name
- NCT04797039
- Testing
- MR guided cryoablation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Prostatic Neoplasms, Prostate Cancer
Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy
Background: Radiation is a common treatment for prostate cancer. It helps damage tumor cells and causes them to die. Radiation can be effective, but some tumors may be harder to treat with radiation or even with surgery.
- Trial name
- NCT01834001
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Cancer Institute (NCI)
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