Clinical trials: Prostate Disease
Prostate Cancer, Prostate Adenocarcinoma
Hemi-Gland Cryoablation for Prostate Cancer at UCLA
This is a prospective data collection of men who are electing to undergo prostate hemi-gland cryoablation. The purpose of this observational research study is to investigate the localized treatment of prostate cancer using…
- Conditions
- Prostate Cancer, Prostate Adenocarcinoma, Prostate Disease
- Trial name
- NCT03503643
- Testing
- Hemigland Cryoablation
- Where
- United States
- Volunteers
- 354 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer, Renal Cancer
Feasibility of a Consumer Based Accelerometer in Monitoring Outpatient Physical Activity: A Study in Patients With Cancer and Amyotrophic Lateral Sclerosis
This is a parallel group, single institution, prospective clinical study. The purpose of this study is to assess whether the Jawbone Up 24, a consumer based accelerometer, can be a feasible tool to study physical activity in…
- Conditions
- Prostate Cancer, Renal Cancer, Brain Cancer, ALS
- Trial name
- NCT02457715
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Prostate Cancer, Psychosocial Stressor
Feasibility of Technology-Based SSIP in Prostate Cancer Patients
The goal of this pilot study is to assess the perceived usability of a smartphone application called WINGS targeting psychosocial distress and well-being in prostate cancer patients and their social network.
- Trial name
- NCT05720832
- Testing
- WINGS-IP1 Smartphone Application
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- Wings Health AG
Prostate Cancer
Radium 223 Following Intermittent ADT
This is a multicentre, phase II, randomized, open label study to evaluate the efficacy and safety of monthly Radium 223 in prolonging the off treatment interval of men with localized prostate cancer receiving intermittent…
- Trial name
- RAND (NCT02656563)
- Testing
- Radium 223 Dichloride (Xofigo®)
- Where
- Canada
- Sponsor
- Canadian Urology Research Consortium
Prostatic Hyperplasia, Benign, Prostate Adenoma
ThuLEP vs. HoLEP vs. Monopolar Enucleation in Management of BPH
Today, endoscopic enucleation of the prostate (EEP) has been recognized a method of choice for treatment of benign prostatic hyperplasia (BPH) of any size, including large-sized glands (>80 cc).
- Conditions
- Prostatic Hyperplasia, Benign, Prostate Adenoma, Lower Urinary Tract Symptoms
- Trial name
- NCT03230721
- Testing
- Thulium-fiber laser enucleation of the prostate, Monopolar enucleation of the prostate, Ho:YAG laser enucleation of the prostate
- Volunteers
- 450 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Breast Cancer, Bladder Cancer
Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients
The basic premise of this research proposal is to determine whether there is any significant association between germline polymorphisms and cancers of colon, bladder, breast, testicular, prostate, ovaries, kidney, lung, lymphoid…
- Conditions
- Breast Cancer, Bladder Cancer, Kidney Cancer, Colon Cancer
- Trial name
- NCT00579514
- Testing
- PCR/PCR/LDR Strategy
- Where
- United States
- Volunteers
- 21,081 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer (Adenocarcinoma), Bladder Cancer
Enhancing Readability of Lay Abstracts and Summaries for Medical Knowledge Using Generative Artificial Intelligence (BRIDGE AI 3)
This trial tests if AI can help make medical info clear and readable. Many patients struggle to find medical informations that easy to read and understand from verified medical sources.
- Conditions
- Prostate Cancer (Adenocarcinoma), Bladder Cancer, Kidney Cancers, Testis Cancer
- Trial name
- NCT07568444
- Testing
- Pub2Post
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Long Term Study of Solifenacin Succinate and Tamsulosin Hydrochloride Oral Controlled Absorption System (OCAS) in Males With Lower Urinary Tract Symptoms
Clinical study to examine the safety, tolerability and efficacy of long-term combination therapy of tamsulosin and solifenacin in the treatment of males with lower urinary tract symptoms (LUTS) associated with benign prostatic…
- Trial name
- Neptune II (NCT01021332)
- Testing
- tamsulosin hydrochloride/solifenacin succinate fixed dose combination (0.4 mg/6 mg), tamsulosin hydrochloride/solifenacin succinate fixed dose combination (0.4 mg/9 mg)
- Where
- 70 sites in Austria, Belarus and 9 more
- Volunteers
- 1,067 people
- Sponsor
- Astellas Pharma Europe B.V.
Prostate Cancer
Vaccination in Prostate Cancer (VANCE)
This is a clinical trial of a new treatment for prostate cancer that is a type of vaccine that could be a new way to treat cancer.
- Trial name
- NCT02390063
- Testing
- ChAdOx1.5T4, MVA.5T4, Cyclophosphamide
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Oxford
Advanced Prostate Cancer
A Long-term Observational Study Cohort in Patients With Advanced Prostate Cancer
The purpose of the protocol is to assess the rate of castration resistance, disease progression and overall survival over a 3-year period post-androgen deprivation therapy (ADT) induction in a study cohort of patients with…
- Trial name
- TRIPTOCARE LT (NCT01383863)
- Where
- 35 sites in Denmark, France and 5 more
- Volunteers
- 180 people
- Sponsor
- Ipsen
Breast Cancer, Prostate Cancer
Artificial Intelligence Supporting CAncer Patients Across Europe - the ASCAPE Project
ASCAPE (Artificial intelligence Supporting CAncer Patients across Europe) is a collaborative research project involving 15 partners from 7 countries, including academic medical centers, SMEs (small and medium-sized enterprises)…
- Conditions
- Breast Cancer, Prostate Cancer, Quality of Life, Survivorship
- Trial name
- ASCAPE (NCT04879563)
- Testing
- ASCAPE-based follow-up strategy
- Where
- 5 sites in Greece, Spain and 2 more
- Volunteers
- 500 people
- Sponsor
- Region Örebro County
Benign Prostatic Hyperplasia, Cognitive Functions
Comparative Neurocognitive Outcomes Following Prostate Surgery
This prospective observational cohort study aims to evaluate postoperative cognitive outcomes in patients undergoing surgical treatment for benign prostatic hyperplasia (BPH).
- Trial name
- NCT07468084
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Cengiz Canakci, MD
Prostate Adenocarcinoma, Stage IIIB Prostate Cancer AJCC v8
MRI Guided Radiation Therapy for the Treatment of High Risk Prostate Cancer
This phase II trial tests whether magnetic resonance imaging (MRI)-guided hypofractionated radiation therapy works to reduce treatment time and side effects in patients with high risk prostate cancer.
- Conditions
- Prostate Adenocarcinoma, Stage IIIB Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8
- Trial name
- NCT05676463
- Testing
- MRI-guided Intensity-Modulated Radiation Therapy, Antiandrogen Therapy, PSMA PET Scan
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Thomas Jefferson University
Stage II Breast Cancer, Stage III Breast Cancer
Ask Questions (ASQ):Implementation of a Communication Intervention
This clinical trial implements a communication intervention to improve patient-oncologist communication in the outpatient medical oncology setting.
- Conditions
- Stage II Breast Cancer, Stage III Breast Cancer, Stage IV Breast Cancer, Stage II Colorectal Cancer
- Trial name
- NCT05025748
- Testing
- Behavioral Intervention
- Where
- 8 sites in United States
- Volunteers
- 81 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Prostate Cancer
GM-CSF for Maintenance of Prostate Cancer for Patients Responding to Taxotere
This trial is designed to investigate the efficacy and safety of GM-CSF used as a maintenance program in patients with androgen-independent prostate cancer (AIPC) who have achieved a maximal response on a taxotere or other…
- Trial name
- NCT00274287
- Testing
- GM CSF
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oncology Specialists, S.C.
Prostate Cancer (Diagnosis)
Development and Validation of a Non-Invasive AI Diagnostic Model for Prostate Cancer Using Multiparametric MRI and PSMA PET/CT
Prostate cancer is one of the most common malignancies in men. Currently, due to the limited diagnostic accuracy of existing imaging tests, there is a risk of missed diagnosis or unnecessary prostate biopsy.
- Trial name
- NCT07690306
- Where
- 6 sites in United States, China
- Volunteers
- 1,500 people
- Sponsor
- Xiangya Hospital of Central South University
Prostatic Neoplasms
Erectile Dysfunction/Prostate/RT/Androgen
The optimal duration of hormonal therapy is yet to be determined in the treatment of locally advanced carcinoma of the prostate.
- Trial name
- NCT00242138
- Testing
- Erectile Dysfunction
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Prostate Cancer
Water Vapor Ablation for Grade Group 3 Prostate Cancer
The goal of this study is to evaluate the safety and effectiveness of the Vanquish Water Vapor Ablation System ("Vanquish") in participants with Grade Group 3 (GG3) intermediate-risk prostate cancer.
- Trial name
- VAPOR 3 (NCT07652164)
- Testing
- Water Vapor Ablation
- Volunteers
- 120 people
- Sponsor
- Francis Medical Inc.
Prostate Cancer
Low-Fat Diet and/or Flaxseed in Preventing Prostate Cancer
RATIONALE: A diet that is low in fat and/or high in flaxseed may slow or prevent disease progression of prostate cancer. PURPOSE: Randomized phase II trial to study the effectiveness of a diet that is low in fat and/or high in…
- Trial name
- NCT00049309
- Testing
- dietary intervention, flaxseed
- Where
- 3 sites in United States
- Volunteers
- 161 people
- Sponsor
- Duke University
Prostate Cancer
Whole Food Plant-based Diet to Improve Outcomes in Prostate Cancer
The purpose of this research is to determine if consuming a whole food plant-based diet for six months impacts outcomes in men with prostate cancer that have a rising prostate-specific antigen (PSA) level.
- Trial name
- NCT07220499
- Testing
- Whole Food Plant-based Diet
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Pacific Cancer Care
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