Clinical trials: Prostate Obstruction
Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Registry of MIUS for Benign Prostatic Obstruction
This national, multicenter, prospective registry aims to collect standardized perioperative and follow-up data on patients undergoing minimally invasive surgical management for benign prostatic obstruction (BPO) in Turkey.
- Trial name
- ReMIUS-BPO (NCT07159165)
- Testing
- Minimally invasive surgical treatment for benign prostatic obstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people
- Sponsor
- Ondokuz Mayıs University
Prostate Cancer
Anesthesia in PROstate Biopsy Pain Obstruction Study
This is a multicentre randomized controlled trial in comparison of the perineal nerve block approach between the periprostatic block in the pain control in men undergo a transperineal prostate biopsy.
- Trial name
- APROPOS (NCT04501055)
- Testing
- perineal nerve block, periprostatic block
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Shanghai East Hospital
Overactive Bladder Syndrome, Bladder Outlet Obstruction
Urodynamics and Clinical Factors That Are Associated With Bladder Over-sensitivity
Urodynamic examination evaluates storage and empting phases of the urinary bladder. It enables the clinician to correlate physiologic findings to patients' complains.
- Conditions
- Overactive Bladder Syndrome, Bladder Outlet Obstruction, Benign Prostate Enlargement, Stress Incontinence (Female) (Male)
- Trial name
- NCT03486639
- Testing
- IPSS questionnaire
- Where
- Israel
- Volunteers
- 330 people
- Sponsor
- Assaf-Harofeh Medical Center
BPH With Urinary Obstruction
Readmission Following Prostatic Surgery
This study will be conducted to estimate readmission rate and reasons for readmission after all modalities of endoscopic transurethral surgeries for treatment of BOO secondary to BPH in the last 20 years.
- Trial name
- NCT06101576
- Testing
- TUIP, TURP, Prostate Vaporization
- Where
- Egypt
- Volunteers
- 4,000 people
- Sponsor
- Mansoura University
BPH With Urinary Obstruction
Early Versus Late Catheter Removal in Patients With Acute Urinary Retention Secondary to BPH Under Tamsulosin Treatment
The aim of this work is to compare between early (3days) and late(7days) removal of urinary catheter after acute urine retention in patients with Benign Prostatic Hyperplasia under Tamsulosin treatment.
- Trial name
- NCT03280420
- Testing
- Early catheter removal, Late catheter removal
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Salem Hassan Salem Mohamed
Phase 1, Healthy
EC905 Pharmacokinetic Profile Study
A study to compare the pharmacokinetics of tamsulosin HCl and solifenacin succinate after co-administration of single entity tablets and of the combination tablet EC905 under steady state conditions at three dose strengths.
- Conditions
- Phase 1, Healthy, Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
- Trial name
- NCT02634489
- Testing
- Tamsulosin HCl, Solifenacin Succinate, EC905
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Benign Prostatic Hyperplasia
Evaluation of the Functional Outcomes After Bilateral, 3D Ultrasound-guided Focal Thermal Ablation of the Prostate Transition Zone, in Patients With Benign Prostatic Hyperplasia-related Obstruction
The aim of the current study is to evaluate the efficacy of transperineal focal microwave ablation (TMA) of the prostate transition zone as a new treatment for lower urinary tract symptoms (LUTS) due to benign prostatic…
- Trial name
- BETTANY (NCT06212453)
- Testing
- Targeted Microwave Ablation
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
BPH, Prostate Obstruction
Prospective Randomized Trial of Irritative Symptoms Severity Assessment After (HoLEP) Versus ThuFLEP
The investigators hypothesize that the functional outcomes of both techniques are comparable. However, ThuFLEP might increase speed recovery of postoperative irritation and early stress urinary incontinence according to the…
- Trial name
- PRISSA (NCT04342533)
- Testing
- Thulium fiber laser enucleation of the prostate, Holmium laser enucleation of the prostate
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Bladder Neoplasm, Prostatic Neoplasms
Preventing Catheter Related Bladder Discomfort (CRBD) With Bilateral Pudendal Nerve Block
Bladder irrigation with a 3 way foley catheter is an important component of post operative management of transurethral bladder surgeries. But it is associated with a high incidence of bladder discomfort.
- Trial name
- NCT05022160
- Testing
- pudendal nerve block
- Where
- Pakistan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Armed Forces Hospital, Pakistan
BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
Efficacy of Mictalase® After ThuLEP
In this single-center, prospective, randomized, open label, phase-III study, patients with indication to Thulium Laser Enucleation of Prostate were enrolled. The report conformed to CONSORT 2010 guidelines.
- Trial name
- NCT05130918
- Testing
- Phenolmicin P3 and Bosexil suppository
- Where
- Italy
- Volunteers
- 111 people
- Sponsor
- San Carlo di Nancy Hospital
Pain, BPH With Urinary Obstruction
Optimizing Pain Control in Transurethral Resection of the Prostate
The purpose of this study is to develop a multi-modal protocol for pain management after TURP that minimizes opioid use. The investigators hypothesize this approach will provide non-inferior pain control to the current standard…
- Conditions
- Pain, BPH With Urinary Obstruction, BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
- Trial name
- NCT04102566
- Testing
- Ibuprofen 600 mg, Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Renal Cell Carcinoma, Adrenal Tumor
The Efficacy and Safety of Chinese Domestic Surgical Robot System in Urological Telesurgery
A single-arm clinical trial was designed in this study. The surgeon will perform urological telesurgery for patients using Chinese domestically produced "MicroHand S" surgical robot system.
- Conditions
- Renal Cell Carcinoma, Adrenal Tumor, Nonfunctioning Kidney, Renal Pelvis Carcinoma
- Trial name
- NCT05739812
- Testing
- telesurgery by domestic surgical robot
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Pain Relief During Prostate Biopsy
Combined Intravenous Diazepam, Local Periprostatic Nerve Block for Prostate Biopsy
Prostate biopsy under transrectal ultrasound (TRUS) guidance is considered the procedure of choice for diagnosing prostate cancer.
- Trial name
- NCT02935972
- Testing
- Diazepam, Lidocaine 1%, Diazepam and Lidocaine 1%
- Where
- Egypt
- Volunteers
- 336 people
- Sponsor
- Assiut University
Benign Prostate Obstruction (BPO)
SteamOne - Prospective Database for Rezum Water Vapor Therapy of the Prostate
This study is to assess the clinical data of Rezum (water vapor therapy) in patients with BPO (benign prostate obstruction) and male LUTS (lower urinary tract symptoms) in terms of efficacy, durability and safety in a large…
- Trial name
- SteamOne (NCT05495633)
- Testing
- Collection and evaluation of clinical (CROMs) and patient-reported outcomes (PROMs), Analysis of uroflowmetry data by EmanoFlow Mobile Application (App) and Emano Clinic Portal
- Where
- 19 sites in Austria, Germany and 1 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Benign Prostate Hyperplasia
Addition of Lidocaine to Levobupivacaine Reduces Intrathecal Block Duration
The main objective was to test the hypothesis that adding lidocaine to hyperbaric levobupivacaine could change the duration of levobupivacaine spinal block.
- Trial name
- NCT01675895
- Testing
- Levobupivacaine lidocaine spinal anesthesia, levobupivacaine Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Diskapi Teaching and Research Hospital
Nocturnal Polyurea in Patients With BPH
Adding Desmopressin to Tamsulosin for Treatment of BPH
In this study investigators will add desmopressin for treatment of patients with benign prostatic hyperplasia and nocturnal polyurea
- Trial name
- NCT05945420
- Testing
- Desmopressin Acetate
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mansoura University
BPH, Nocturia
Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate Hypertrophy
Benign prostate hypertrophy (BPH) and inflammation are common non-cancerous enlargement of the prostate, which result in urinary interference and incomplete drainage of the bladder.
- Conditions
- BPH, Nocturia, BPH With Urinary Obstruction, Prostatism
- Trial name
- SVF-BPN (NCT02961114)
- Testing
- Microcannula Harvest Adipose, Centricyte 1000, IV Sterile Normal Saline
- Where
- 2 sites in United States
- Sponsor
- Robert W. Alexander, MD, FICS
Prostatic Hyperplasia
Benign Prostatic Hyperplasia (BPH) Screening Tool Case Finding Study in Subjects >=50 Years
This non-randomized, interventional study will be conducted in a general practice setting to assess the utility of a benign prostatic enlargement (BPE)/benign prostatic obstruction (BPO) screening tool in conjunction with…
- Trial name
- NCT02757963
- Testing
- Benign prostatic enlargement (BPE)/Benign prostatic obstruction (BPO) screening tool, International Prostate Symptom Score (IPSS) screening tool
- Where
- 45 sites in France, Germany and 3 more
- Volunteers
- 1,679 people
- Sponsor
- GlaxoSmithKline
BPH With Urinary Obstruction, BPH
Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP
Holmium Laser Enucleation of the Prostate (HoLEP) is a size-independent treatment option for benign prostatic hypertrophy (BPH) as recommended by the American Urological Association (AUA) Guidelines.
- Conditions
- BPH With Urinary Obstruction, BPH, Hematuria, Same Day Discharge
- Trial name
- NCT05620784
- Testing
- Furosemide
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Northwestern University
BPH, Intravesical Botox
Prostate Enucleation With Intravesical Botox Injections in Treating BPH and Bladder Overactivity
The aim of this study is to evaluate the effect of intravesical Botox injections on lower urinary tract symptoms (LUTS) when administered during Bipolar prostate enucleation surgery in patients with bladder outlet obstruction…
- Conditions
- BPH, Intravesical Botox, Bipolar Enucleation of the Prostate, Overactive Bladder
- Trial name
- BPH Botox (NCT05910983)
- Testing
- Bipolar enucleation of the prostate (BipolEP), Intravesical Botox injection
- Volunteers
- 100 people
- Sponsor
- Menoufia University