Clinical trials: Prostatectomy
Prostate Adenocarcinoma, Prostate Cancer
Single-Port Transvesical Partial Prostatectomy Versus High Intensity Focused Ultrasound
This study aims to compare the novel single-port robotic partial prostatectomy to High-intensity focused ultrasound (HIFU) in patients with low to intermediate risk localized prostate cancer.
- Trial name
- NCT05610852
- Testing
- Transvesical Single Port Robotic Partial Prostatectomy, High-intensity focused ultrasound (HIFU)
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- Case Comprehensive Cancer Center
Erectile Dysfunction, Sexual Dysfunction, Physiological
Study to Compare the Tolerability and Efficacy of Once Daily Vardenafil vs Vardenafil PRN vs Placebo in Men Immediately After Nerve-sparing Prostatectomy for Improving ED
A study to assess the efficacy of vardenafil, taken as a tablet both nightly or 'as needed' (immediately before intended sexual activity) compared to placebo, to evaluate its tolerability and if it can help in recovery of…
- Trial name
- NCT00492635
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 86 sites in United States, Austria and 13 more
- Volunteers
- 628 people
- Sponsor
- Bayer
Prostate Cancer, Erectile Dysfunction
The Ability of Adipose Flap Over the NVB to Improve Sexual and Urinary Function Following Radical Prostatectomy
Despite technological advances, incontinence and impotence remain significant side effects of radical prostatectomy (RP). Strategies have been developed to reduce the injury to the erection nerves (i.e.
- Conditions
- Prostate Cancer, Erectile Dysfunction, Urinary Incontinence
- Trial name
- NCT04577222
- Testing
- Technical modification during radical prostatectomy
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Prostate Cancer, Urinary Tract Infection
Antibiotic Prophylaxis for Urinary Catheter Removal After Radical Prostatectomy
The aim of this study is to determine whether antibiotics prophylaxis at the time of urinary catheter removal decreases the number of symptomatic urinary tract infections in patients after radical prostatectomy.
- Conditions
- Prostate Cancer, Urinary Tract Infection, Clostridium Difficile
- Trial name
- Abx (NCT02247960)
- Testing
- Ciprofloxacin
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of Rochester
Urinary Incontinence (UI)
Urinary Incontinence After Endoscopic Prostatectomy
This is a prospective cohort study aiming to identify the preoperative and intraoperative predictors of urinary incontinence after endoscopic transurethral bipolar prostatectomy
- Trial name
- NCT06939140
- Testing
- Bipolar prostatectomy
- Where
- Egypt
- Volunteers
- 133 people
- Sponsor
- Assiut University
Prostate Cancer
Outcomes From a RCT Comparing Preventive Versus Delayed Ligation of DVC During Robot-assisted Radical Prostatectomy
Since its introduction, robot-assisted radical prostatectomy (RARP) have become the standard surgical approach for the treatment of prostate cancer in the United States and then in Europe.
- Trial name
- NCT03351088
- Testing
- DVC ligation
- Where
- Italy
- Volunteers
- 226 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Prostate Adenocarcinoma, Localized Prostate Carcinoma
Extraperitoneal SINgle-port rObotic-assisted Radical Prostatectomy (RARP) Versus Transperitoneal Multi-port RARP in the Treatment Of Prostate Cancer (SINO-TOP)
This study is a two-arm, multicenter, randomized controlled clinical trial on whether single-port extraperitoneal VIP RARP is non-inferior to multi-port transperitoneal RARP in terms of functional recovery rate and other key…
- Trial name
- NCT06238713
- Testing
- Single-port extraperitoneal robotic-assisted radical prostatectomy with Vattikuti Institute Prostatectomy（VIP） techniques, Multi-port transperitoneal robotic-assisted radical prostatectomy with bilateral intrafascial nerve-sparing techniques
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Shanghai Changzheng Hospital
Prostatic Neoplasms, Cancer of Prostate
Study to Evaluate the Clinical Impact of a Laparoscopic Radical Prostatectomy Simulator
To evaluate the clinical impact of an online video simulator during the learning period of laparoscopic radical prostatectomy.
- Conditions
- Prostatic Neoplasms, Cancer of Prostate, Prostate Cancer, Prostate Neoplasms
- Trial name
- PERLE (NCT00999960)
- Testing
- Laparoscopic Radical Prostatectomy (without a simulator), Laparoscopic Radical Prostatectomy (with a simulator)
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy: a Randomized Controlled Trial
This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate…
- Trial name
- NCT07863388
- Testing
- Autologous Platelet Rich Plasma
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev and Gentofte Hospital
Prostate Adenocarcinoma
SURPASS: Stereotactic Ultra-hypofractionated Radiotherapy for Post-prostatectomy Patients: Adaptive Salvage SBRT
The purpose of the study is to evaluate the safety and feasibility of daily-adaptive post-prostatectomy stereotactic body radiotherapy (SBRT) to the prostate fossa in men undergoing salvage radiotherapy after radical…
- Trial name
- NCT07888283
- Testing
- Adaptive stereotactic body radiotherapy (SBRT)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Prostate Cancer
Personalized Radiotherapy for Biochemical Recurrence of Prostate Cancer After Prostatectomy.
A randomized phase III trial to study the effect of adding lymph node irradiation in patients with poor prostate-specific antigen (PSA) response during salvage radiotherapy for biochemical recurrence (0.15 ≤ PSA <0.70 ng/ml)…
- Trial name
- PROPER2 (NCT04858880)
- Testing
- Radiation to the prostate bed with or without addition of radiation of lymph node irradiation.
- Where
- 3 sites in Sweden
- Volunteers
- 374 people
- Sponsor
- Lund University Hospital
Urinary Incontinence
Safety and Efficacy Study of USTRAP™ in Male Urinary Incontinence
Few surgical methods to treat male stress urinary incontinence have been assessed in comparative, randomised interventional studies. Ustrap is a new adjustable-pressure 4-arm device.
- Trial name
- PROSPECT (NCT03323554)
- Testing
- Ustrap®, AMS 800®
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Quanta Medical
Prostate Cancer
The Effect of Exercise on Tumor Hypoxia in Men With Localized Prostate Cancer Undergoing Radical Prostatectomy.
Background and purpose: The purpose of this study is to investigate the effect of one acute exercise bout on tumor hypoxia in patients with localized prostate cancer undergoing radical prostatectomy.
- Trial name
- SHOR-TEST (NCT03675529)
- Testing
- High Intensity Interval Training bout
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Urinary Incontinence, Erectile Dysfunction
Effectiveness of Physiotherapy to Treat the Urinary Incontinence and Erectile Dysfunction Post Retropubic Prostatectomy
The prostate cancer is the most common parenchymal neoplasia in men over 45 years old. Radical prostatectomy is curative treatment is most used today.
- Trial name
- NCT02226237
- Testing
- group of pelvic floor exercises, anal electrostimulation group
- Where
- Brazil
- Volunteers
- 237 people
- Sponsor
- Barretos Cancer Hospital
Prostate Cancer
Optimizing Timing of rhPSMA-7.3 (18F) for Assessing Site(s) of Recurrent Disease Following Radical Prostatectomy
All men following Radical Prostatectomy (RP) at NYU Langone Health undergo routine prostate specific antigen (PSA) testing in order to identify disease recurrence.
- Trial name
- NCT05678322
- Testing
- 18F-Labeled Positron Emission Tomography (PET) Diagnostic Agent, PET MRI Imaging
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- NYU Langone Health
Prostatic Neoplasms, Urinary Incontinence
Preservation of Endopelvic Fascia: Effects on Postoperative Incontinence and Impotence. Randomized Clinical Trial.
Urinary incontinence and impotence are typical disturbances after radical prostatectomy. Although, several surgical methods are developed to decrease these disturbances, 8% and 50% of the patients suffer from permanent urinary…
- Conditions
- Prostatic Neoplasms, Urinary Incontinence, Erectile Dysfunction
- Trial name
- NCT02526602
- Testing
- Preservation (endopelvic fascia), Opening (endopelvic fascia)
- Where
- Finland
- Volunteers
- 158 people
- Sponsor
- Tampere University Hospital
Prostate Cancer
A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery
Patients with post-prostatectomy PSA (Prostate Specific Antigen) recurrences with aggressive disease features will receive salvage radiation therapy and standard androgen deprivation therapy (ADT) or enhanced ADT to determine if…
- Trial name
- STEEL (NCT03809000)
- Testing
- Radiation Therapy, Enzalutamide, Bicalutamide
- Where
- 108 sites in United States, Canada
- Volunteers
- 188 people
- Sponsor
- RTOG Foundation, Inc.
Prostate Cancer
Clinical Study of SU011248 in Subjects With High Risk Prostate Cancer Who Have Elected to Undergo Radical Prostatectomy
Prostate cancer is prevalent in the United States, with approximately 230,110 new cases and 29,900 deaths in 2004. Approximately 30% of new cases will be clinical stage T3 when they are diagnosed.
- Trial name
- NCT00790595
- Testing
- SU011248
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Male Urogenital Diseases, Female Urogenital Diseases
Comparison of Gas Consumption From Two Different Anesthesia Machines
Low flow anesthesia (LFA) is used less than desirable, partly because one has considered that there might be danger of underdosing of anesthesia gas and thus risk of awareness under anesthesia.LFA has several advantages such as…
- Trial name
- NCT02774031
- Testing
- Aisys with Et control, Aisys conventional, Flow-i with ACG
- Where
- Norway
- Volunteers
- 147 people
- Sponsor
- St. Olavs Hospital
High Risk Prostate Cancer
Neoadjuvant BKM120 in High-risk Prostate Cancer
This is a phase II, study of BKM120 in patients with high-risk, localized prostate cancer. Eligible patients will be enrolled and scheduled to have an ultrasound-guided biopsy of the prostate to confirm high-risk disease and…
- Trial name
- NCT01695473
- Testing
- BKM120
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Won Kim