Clinical trials: Prostatic Biopsy
Stress
The Effect of Using a Stress Ball During Transrectal Ultrasound-Guided Prostate Biopsy on Anxiety, Pain, and Hemodynamic Variables
The Effect of Using a Stress Ball During Transrectal Ultrasound-Guided Prostate Biopsy on Anxiety, Pain, and Hemodynamic Variables
- Trial name
- Stress ball (NCT07507617)
- Testing
- Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Mersin University
Carcinoma Prostate
Efficacy of Diclofenac Suppository for Pain Control in Ultrasound Guided Biopsy of Prostate
Transrectal ultrasound guided biopsy of prostate (TRUS-Bx) is widely used as accepted mode of investigation for prostate cancer in current urology practice.
- Trial name
- NCT01939743
- Testing
- Diclofenac suppository plus lidocaine gel, Lidocaine gel only
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Prostate Biopsy
Evaluation of the Effect on Pain of Attentional Diversion Associated with Hypnotic Induction by Virtual Reality (VRH) in Perioperative Prostate Biopsies Under Local Anesthesia:
The primary objective of the study is to prospectively compare perioperative pain assessed in patients undergoing targeted prostate biopsies, either transrectally or transperineally, under local anesthesia with or without a…
- Trial name
- HYPNOSURG-VR (NCT06691438)
- Testing
- prostate biopsy
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Grenoble
Prostate Cancer
Evaluation of Targeted Biopsy Plus Sextant Biopsy in Diagnosis of Prostate Cancer
The goal of this randomized controlled trial (RCT) is to evaluate the efficacy and safety of different prostate biopsy schemes, including targeted biopsy plus sextant biopsy (3TB+6SB) and combination of targeted biopsy and…
- Trial name
- NCT06684652
- Testing
- 3TB+6SB, 3TB+12SB
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
Prostate Cancer (Adenocarcinoma), Prostate Cancer (Diagnosis)
Development of an Intraoperative Adaptive Biopsy System for Prostate Cancer: Integrating Imaging Navigation With Metabolic Feedback for Dynamic Decision-Making
Development of an Intelligent System Integrating Preoperative Imaging and Real-Time Intraoperative Metabolic Feedback to Dynamically Optimize Biopsy core Placement for Individualized Precision Sampling.
- Trial name
- NCT07856017
- Where
- 4 sites in China
- Volunteers
- 90 people
- Sponsor
- Shanghai Zhongshan Hospital
Aromatherapy, Prostate Cancer
Aromatherapy on Pain and Anxiety of the Patients Undergoing Prostate Biopsy
The study included 120 male patients who would undergo a prostate biopsy. Patients were divided into 3 groups as placebo group (n = 40), Levander group (N = 40), and Frankincense group (n = 40).
- Conditions
- Aromatherapy, Prostate Cancer, Anxiety
- Trial name
- NCT06119438
- Testing
- Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mersin Training and Research Hospital
Diagnoses Disease
Micro-Ultrasound/Magnetic Resonance Imaging 001
Micro-ultrasound is a novel real-time imaging modality which maintains the clinical workflow of conventional ultrasound-guided prostate biopsy, while potentially maintaining a similar ability to detect clinically significant…
- Trial name
- NCT03938376
- Testing
- Micro-Ultrasound guided biopsy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Metastatic Castration-resistant Prostate Cancer (mCRPC), Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate Cancer
ProBio is an international, outcome-adaptive, multi-arm, open-label, multiple assignment randomized biomarker driven platform trial in patients with metastatic prostate cancer.
- Trial name
- ProBio (NCT03903835)
- Testing
- Enzalutamide Oral Capsule, Abiraterone Oral Tablet, Carboplatin
- Where
- 32 sites in Belgium, Norway and 2 more
- Volunteers
- 750 people
- Sponsor
- Karolinska Institutet
Prostate Cancer, Prostate Adenocarcinoma
Utility of Adding MR Fusion to Standard US Guided Prostate Biopsy
The purpose of this study is to utilize this technology in the early detection and staging of pathologic states within prostate cancer patients using the information obtained on mpMRI and serum biomarkers from the patient's blood…
- Trial name
- NCT05064111
- Testing
- TRUS biopsy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Arizona
Neoplasms of the Prostate
MRI/US Fusion Imaging and Biopsy in Combination With Nanoparticle Directed Focal Therapy for Ablation of Prostate Tissue
To determine the efficacy of using MRI/US fusion imaging technology to direct focal ablation of prostate tissue using nanoparticle-directed laser irradiation.
- Trial name
- NCT02680535
- Testing
- AuroShell particle infusion
- Where
- 5 sites in United States
- Volunteers
- 45 people
- Sponsor
- Nanospectra Biosciences, Inc.
Prostate Cancer
Prostate Cancer Burden and Heterogeneity Evaluation Towards Liquid Biopsy: a Correlation Study to 18FDCFPyL PET and Patients Outcome
This is a prospective, monocentric, proof of concept study aims to identify in prostate cancer patients, a potential relationship between CTC-PSMA positivity and 18F-PET-PSMA results as well as patient outcome.
- Trial name
- TAYLOR (NCT06917781)
- Testing
- Patients with 18F-PET-PSMA indication
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Institut Claudius Regaud
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Prostate Biopsy, Post Biopsy Bleeding
Routine Probe Compression After Transrectal Prostate Biopsy(RPCAB) to Reduce Bleeding and Infectious Complications
Hematuria (up to 50%) and rectal bleeding (up to 30%) are common complications following transrectal ultrasound-guided prostate biopsy. Although most cases are mild, some require additional intervention.
- Conditions
- Prostate Biopsy, Post Biopsy Bleeding, Transrectal Ultrasound-guided Prostate Biopsy
- Trial name
- RPCAB (NCT07550985)
- Testing
- Probe compression
- Where
- South Korea
- Volunteers
- 324 people
- Sponsor
- Veterans Health Service Medical Center, Seoul, Korea
Prostate Cancer
Positron Emission Tomography / Magnetic Resonance Imaging (PET/MRI) Guided Biopsy in Men With Elevated PSA
In 22% of patients with elevated Prostate-specific antigen (PSA) MRI guided biopsy will not detect significant prostate cancer (PCA) (defined as either: Gleason score (GS) ≥ 3+4 or tertiary pattern 5, or final stage ≥ pT3a and/or…
- Trial name
- NCT03187990
- Testing
- [68Ga]PSMA-11, [18F]PSMA-1007
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Irene Burger
Prostate Carcinoma
Ultrasound-Based Imaging Using the Aixplorer System in Diagnosing Prostate Cancer in Patients Undergoing Biopsy
This clinical trial studies an ultrasound-based imaging procedure called elastography using the Aixplorer system in diagnosing prostate cancer in patients undergoing biopsy.
- Trial name
- NCT03013413
- Testing
- Shear Wave Elastography, Ultrasound Elasticity Imaging, Ultrasound-Guided Prostate Biopsy
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Prostate Biopsy
Difference in Pain Perception by Patients With Prostate Biopsy Using Instillagel Compared With Guided Ultrasound Gel
This is a randomized controlled trial. One group (intervention group) will get in advance to the prostate biopsy rectal approximately 5 cc Instillagel.
- Trial name
- NCT02819713
- Testing
- ultrasound gel, Instillagel
- Where
- Netherlands
- Sponsor
- Rijnstate Hospital
Prostate Cancer
Fusion Targeted Biopsy of the Prostate
The objective of the proposed study is to evaluate a new, molecular image directed, three-dimensional (3D) ultrasound guided biopsy system in human patients. The current biopsy uses ultrasound imaging as guidance.
- Trial name
- NCT02013414
- Testing
- 3D ultrasound-guided biopsy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Emory University
Men Who Must Undergo a Prostate Biopsy Related to Prostate Cancer Suspicion.
Short or Long Schemes of Antibiotic Prophylaxis for Prostate Biopsy
The purpose of this study is to determine whether long antibiotic prophylactic is more effective than a short traitement in infective complications for prostate biopsy
- Trial name
- NCT00294749
- Testing
- Ciprofloxacine
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Poitiers University Hospital
Prostate Cancer
Application of a Novel Model Based on Plasma cfDNA Assay and MRl Imaging in the Detection of Prostate Cancer
The goal of this diagnostic test is to obtain multiple cell-free DNA （cfDNA） fragment profiles of subjects by whole genome sequencing based on plasma cfDNA, build a prostate cancer prediction model by machine learning, and to…
- Trial name
- NCT06509919
- Testing
- Blood draw and MRI scans
- Where
- 10 sites in China
- Volunteers
- 1,600 people
- Sponsor
- Shanghai Changzheng Hospital
Prostate Cancer, Adverse Effects Surgery
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia.
- Conditions
- Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound
- Trial name
- TPF-LITT (NCT05698576)
- Testing
- TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC