Clinical trials: Prostatic Disease
Prostate Cancer
11C- and 18F-Choline PET/MR Imaging for Prostate Cancer
This phase II trial studies how well 11C-choline (carbon C 11 choline) and 18F-choline (fluorine F 18 choline) positron emission tomography/magnetic resonance (PET/MR) imaging works in diagnosing patients with unfavorable…
- Trial name
- NCT02397408
- Testing
- Carbon C 11 Choline, Fluorine F 18 Choline, Positron Emission Tomography (PET) / Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of California, San Francisco
Prostatic Neoplasms, Prostate Cancer
Multi-Center Trial of High-resolution Transrectal Ultrasound Versus Standard Low-resolution Transrectal Ultrasound for the Identification of Clinically Significant Prostate Cancer
This trial uses a ultra high-resolution ultrasound system and specialized transducer, intended for use in prostate imaging. The system's image resolution is significantly better than the standard of care, due to its higher…
- Conditions
- Prostatic Neoplasms, Prostate Cancer, Cancer of the Prostate
- Trial name
- NCT02079025
- Testing
- High-resolution ultrasound guided prostate biopsy, Standard ultrasound guided prostate biopsy
- Where
- 5 sites in United States, Canada
- Volunteers
- 1,676 people
- Sponsor
- Exact Imaging
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Dutasteride for Improving Peri-Operative and Long-Term Outcomes of Photoselective Vaporization of the Prostate (DOP)
This study is for individuals electing to have GreenLight Photoselective Vaporization of the Prostate (PVP) to treat symptoms from an enlarged prostate gland.
- Trial name
- NCT00274417
- Testing
- dutasteride
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Urology of Virginia
Prostate Cancer
Quality of Life in Men With High Risk Localized Prostate Cancer
Primary Objectives: 1. To describe patient quality of life (QOL) related to bladder, bowel, and sexual function, as well as mental and physical health, in patients who received neoadjuvant investigational therapies prior to…
- Trial name
- NCT00877617
- Testing
- QOL Questionnaire
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms
Long Term Follow up of Water Vapor Thermal Therapy (Rezum) for Benign Prostatic Hyperplasia (BPH)
This study aims to assess the effectiveness and morbidity of water vapor thermal therapy (Rezūm therapy) for benign prostatic hyperplasia (BPH).
- Trial name
- NCT05982444
- Testing
- water vapor thermal therapy (Rezum) for prostate
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Helwan University
Prostate Cancer, Pain Cancer
Determining the Effect of Abiraterone on the Metabolism of Oxycodone in Men With Prostate Cancer (the ENABLE Study)
Prostate cancer often leads to bone metastases, which require adequate pain management with opioids such as oxycodone. This study investigates whether abiraterone - a drug used in the treatment of prostate cancer - affects the…
- Trial name
- ENABLE (NCT07001709)
- Testing
- Oxycodone oral capsule 15 mg, Abiraterone Acetate Tablets 500 mg
- Where
- Netherlands
- Volunteers
- 29 people
- Sponsor
- Deventer Ziekenhuis
Recurrent Prostate Cancer, Stage I Prostate Cancer
The Immuno-Response to Primary Cryotherapy for the Treatment of Prostate Cancer
This randomized pilot phase I trial studies how well sargramostim after cryotherapy works in treating patients with prostate cancer.
- Conditions
- Recurrent Prostate Cancer, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
- Trial name
- NCT02250014
- Testing
- cryotherapy, sargramostim
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Colorado, Denver
Prostate Cancer
Neoadjuvant Dasatinib Plus LHRH Analogue Therapy in High-Risk Localized Prostate Cancer
This trial will investigate the activity of dasatinib plus LHRH analogue therapy in high-risk localized prostate cancer.
- Trial name
- NCT00860158
- Testing
- Dasatinib, Leuprolide Acetate (LHRH Analogue), Radical Prostatectomy
- Where
- 6 sites in United States
- Volunteers
- 1 people
- Sponsor
- Noah Hahn, M.D.
Prostate Carcinoma, Erectile Function
Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Robot-assisted Surgical Treatment of Genitourinary Cancers
This prospective randomized controlled trial (RCT) is designed to provide high level evidence on the efficacy of Low-intensity Extracorporeal Shock Wave Therapy (Li-ESWT) in the treatment of post-Robot-Assisted (RA) Radical…
- Conditions
- Prostate Carcinoma, Erectile Function, Genito Urinary Cancer
- Trial name
- RCT_LiESWT (NCT06717711)
- Testing
- Low-intensity Extracorporeal Shock Wave Therapy (LiESWT), PDE5 inhibitor (tadalafil)
- Where
- 2 sites in Italy
- Volunteers
- 158 people
- Sponsor
- Regina Elena Cancer Institute
Epidemiology, Prostate Cancer
Diet, Physical Activity and Related Candidate Biomarkers in Relation to Prostate Cancer Risk (BIOCaPPE)
The risk of prostate cancer is associated with lifestyle habits, such as diet and physical activity. Indeed, results of numerous studies suggest links between obesity, diabetes, inflammation and androgen and estrogen metabolism…
- Trial name
- BIOCaPPE (NCT03383016)
- Testing
- Lifestyle questionnaires, Prostate Biopsy
- Where
- 4 sites in Canada
- Volunteers
- 2,053 people
- Sponsor
- CHU de Quebec-Universite Laval
Prostate Cancer
FDG Positron Emission Tomography and Computed Tomography (PET-CT) in Metastatic Prostate Cancer
This is an National Institute of Health (NIH) funded, investigator-initiated, single center prospective study to investigate the ability of the new dual-modality positron emission tomography and computed tomography (PET-CT)…
- Trial name
- NCT00282906
- Testing
- hybrid PET-CT imaging system
- Where
- United States
- Volunteers
- 257 people
- Sponsor
- University of Southern California
Prostate Cancer
Epirubicin and Docetaxel in Treating Patients With Metastatic Prostate Cancer
RATIONALE: Drugs used in chemotherapy, such as epirubicin and docetaxel, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00096304
- Testing
- docetaxel, epirubicin hydrochloride
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Medical University of South Carolina
Prostatic Neoplasms
Retrospective Observational Study Investigating Fluciclovine (18F) (FACBC)
This retrospective observational multi centered study has been established to collect the clinical experience relating to the administration of Fluciclovine 18F employed in both investigator initiated studies and named…
- Trial name
- NCT02443571
- Testing
- Fluciclovine (18F)
- Where
- 4 sites in United States, Italy and 1 more
- Volunteers
- 714 people
- Sponsor
- Blue Earth Diagnostics
Benign Prostatic Hyperplasia
Study to Evaluate the Bioequivalence of Astellas Phama Korea Inc. "Harnal-D" in Healthy Volunteers After Meal
This study is an open-label, randomized, fed, single dose, crossover study to evaluate the bioequivalence of Chong Kun Dang Pharmaceutical "Chong Kun Dang Tamsulosin HCl Tablet" and Astellas Phama Korea Inc.
- Trial name
- NCT03887871
- Testing
- Harnal-D Tab., Chong Kun Dang Tamsulosin HCl Tab.
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Prostate Cancer
SWITCH: Study of the Prednisone to Dexamethasone Change in mCRPC Patients Treated With Abiraterone
Abiraterone acetate (AA) has shown a favourable impact in overall survival, administered with prednisone to decrease the adverse event related to CYP171A suppression.
- Trial name
- NCT02928432
- Testing
- Steroids switch
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Centro Nacional de Investigaciones Oncologicas CARLOS III
Prostate Cancer, Urologic Cancer
The Man Van Project
National Health Service (NHS) England has commissioned The Royal Marsden Hospital NHS Foundation Trust to run a novel mobile clinical outreach service called 'Man Van' with the aim of enabling male patients' easy access to care…
- Conditions
- Prostate Cancer, Urologic Cancer, Urologic Diseases, Bladder Cancer
- Trial name
- MV (NCT06357416)
- Testing
- MV-POCT Sub-study, Main Man Van Group Sub-study (MV-Eco), MV-QualQ Sub-study
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Head and Neck Neoplasm, Prostatic Neoplasm
Study Of PF-00562271, Including Patients With Pancreatic, Head And Neck, Prostatic Neoplasms
Phase 1 safety, pharmacokinetics, and pharmacodynamics trial of the focal adhesion kinase (FAK) inhibitor PF-00562271 in patients with positive Positron Emission Tomography [PET] scans due to advanced non-hematologic…
- Conditions
- Head and Neck Neoplasm, Prostatic Neoplasm, Pancreatic Neoplasm
- Trial name
- NCT00666926
- Testing
- PF00562271
- Where
- 4 sites in United States, Australia and 1 more
- Volunteers
- 99 people
- Sponsor
- Verastem, Inc.
Male Breast Carcinoma, Prostate Adenocarcinoma
Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Breast Cancer, Non-small Cell Lung Cancer, or Prostate Cancer
This phase I trial studies the side effects and the best dose of stereotactic body radiation therapy in treating patients with breast cancer, non-small cell lung cancer, or prostate cancer that has spread to other parts of the…
- Conditions
- Male Breast Carcinoma, Prostate Adenocarcinoma, Recurrent Breast Carcinoma, Recurrent Non-Small Cell Lung Carcinoma
- Trial name
- NCT02206334
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- 78 sites in United States, Canada and 1 more
- Volunteers
- 42 people
- Sponsor
- NRG Oncology
Prostate Cancer, Erectile Dysfunction
Athermal Nerve-sparing During Robotic-assisted Radical Prostatectomy Using a Hemostatic Matrix.
The purpose of this study is to evaluate the use of a hemostatic gelatine-thrombin matrix during athermal nerve-sparing prostate resection compared to conventional hemostasis using electrocautery in patients with localized…
- Trial name
- AnPro (NCT01448798)
- Testing
- Application of a hemostatic gelatin-thrombin matrix, Use of mono- and bipolar electrocautery and surgical clips
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Prostate Cancer
Cancer DNA Detection in Blood and Urine
This study is being conducted to collect and analyze biospecimens (blood and urine) and clinical data from patients with prostate cancer as well as healthy volunteers to better understand the differences between cancer cells and…
- Trial name
- NCT02657863
- Testing
- Urine collection and blood draw
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins