Clinical trials: Prostatic Hyperplasia
Benign Prostatic Hyperplasia
QUAPELLA (QUAlity of Prostate Enucleation by LUMENIS - Laser)
This observational study aims at describing the learning curve of the Holmium Enucleation of the Prostate (HoLEP) technique using a LUMENIS laser device by senior attending urologists.
- Trial name
- QUAPELLA (NCT01534793)
- Testing
- Holmium Laser Enucleation of the Prostate (HoLEP)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Benign Prostatic Hyperplasia
Study of PRX302 for Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia (BPH)
The purpose of this study is to evaluate the safety, tolerability and efficacy of a single treatment of PRX302 for the treatment of Benign Prostatic Hyperplasia (BPH) as compared to placebo.
- Trial name
- NCT01454349
- Testing
- PRX302
- Where
- 15 sites in United States
- Volunteers
- 40 people
- Sponsor
- Sophiris Bio Corp
Benign Prostatic Hyperplasia
Comparison of TUSP Versus TURP for Treatment of Benign Prostatic Hyperplasia in a Small Prostate Volume
Comparison of transurethral split of the prostate versus transurethral resection of the prostate for treatment of benign prostatic hyperplasia in a small prostate volume: A prospective controlled study
- Trial name
- NCT04912349
- Testing
- TUSP, TURP
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Prostate Hyperplasia
BETTY: BEnign Prostatic Hyperplasia Transperineal Targeted Microwave therapY
This is a pilot study on applying 3D-Ultrasound-Guided Transperineal Microwave needle ablation for men with symptomatic benign prostatic hyperplasia (BPH).
- Trial name
- NCT05443451
- Testing
- 3D-Ultrasound-Guided Transperineal Microwave needle ablation of BPH
- Where
- Hong Kong
- Volunteers
- 12 people
- Sponsor
- Chinese University of Hong Kong
Benign Prostatic Hyperplasia
Interest of a Systematic Assessment of the Treatment of LUTS in the Management of BPH
The high level of unsatisfactory outcome observed in patients treated for LUTS associated with BPH with respect to the different existing therapeutic options strongly emphasizes the need for treatment optimisation in daily…
- Trial name
- UROEVAL (NCT03179670)
- Where
- France
- Volunteers
- 625 people
- Sponsor
- RECORDATI GROUP
Prostatic Hyperplasia
Prostate Artery Embolization as a Treatment for Benign Prostatic Hyperplasia in Men With Prostates Larger Than 90 Grams
The purpose of the study is to evaluate improvement in symptoms related to benign prostatic hyperplasia (BPH) in men treated with prostate artery embolization (PAE) using Embosphere Microspheres.
- Trial name
- NCT02396420
- Testing
- Embosphere Microspheres
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- South Florida Medical Imaging, PA
Overactive Bladder
Study to Evaluate the Efficacy, Safety and Tolerability of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia (BPH)
This study will assess the efficacy of vibegron compared with placebo in men with overactive bladder (OAB) symptoms on pharmacological therapy for benign prostatic hyperplasia (BPH) as defined by micturition and urgency episodes.
- Trial name
- NCT03902080
- Testing
- Vibegron
- Where
- 140 sites in United States, Belgium and 6 more
- Volunteers
- 1,105 people
- Sponsor
- Urovant Sciences GmbH
Prostatic Hyperplasia
Dutasteride (GI198745) In Benign Prostatic Hyperplasia Subjects
This study will assess the efficacy and safety of GI198745 0.5mg given once daily for 52 weeks to Benign Prostatic Hyperplasia (BPH) patients.
- Trial name
- NCT00368979
- Testing
- Dutasteride
- Where
- 26 sites in Japan
- Volunteers
- 378 people
- Sponsor
- GlaxoSmithKline
Nonmalignant Neoplasm, Prostate Cancer
MRI and Magnetic Resonance Spectroscopy Imaging in Patients Receiving Dutasteride for Benign Prostatic Hypertrophy and Low-Risk Prostate Cancer
RATIONALE: Diagnostic procedures, such as MRI and magnetic resonance spectroscopy imaging, may help in learning how well dutasteride works in patients with benign prostatic hypertrophy and low-risk prostate cancer.
- Trial name
- NCT00706966
- Testing
- dutasteride
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Enlarged Prostate (BPH), Benign Prostatic Hyperplasia
Moses 2.0 vs Magneto for HoLEP - a Randomized Controlled Trial
The objective of this study is to compare the Magneto 150 holmium laser to the current MOSES 2.0 technology to see if there is a benefit in decreased hemostasis time intraoperatively.
- Trial name
- NCT07632742
- Testing
- Magneto 150 holmium laser, Moses 2.0 holmium laser
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Benign Prostate Hyperplasia, Bladder Tumor
Effective Dose of Dexmedetomidine for Sedation in Patients Undergoing TURP/TURB Under Spinal Anesthesia With or Without Fentanyl by Age Groups: Randomized Comparative Study
Recently many studies reported that intraoperative dexmedetomidine administration undergoing spinal anesthesia give a satisfactory sedation in elderly patients and cause less respiratory depressions compared other sedatives(e.g.
- Trial name
- NCT01665586
- Testing
- dexmedetomidine
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Yonsei University
Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Clinical Trial on the Effectiveness of TUMT Compared to PAE in Reducing Severe LUTS in Men with BPH
The TUMT-PAE-1 trial is a randomised clinical trial aiming to compare the effectiveness of transurethral microwave thermotherapy (TUMT) with prostatic artery embolisation (PAE) in reducing urinary symptoms caused by prostate…
- Trial name
- TUMT-PAE-1 (NCT05686525)
- Testing
- Transurethral Microwave Thermotherapy, Prostate Artery Embolisation
- Where
- 3 sites in Denmark
- Volunteers
- 220 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prostate Hyperplasia
HoLEP Vs BPEP for Large Prostatic Adenoma
Benign prostatic hyperplasia (BPH) is one of the most common urinary disorders in elderly males. The symptoms of BPH include impaired physiological and functional well-being, which interferes with daily living.
- Trial name
- enucleation (NCT04275076)
- Testing
- Holmium laser enucleation of the prostate versus bipolar transurethral enucleation of the prostate in management of benign prostatic hyperplasia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ahmed Maher Gamil Ahmed Higazy
Hyperplasia Prostatic
Bioequivalence Study of Tansulosine 0,4 mg Capsule in Health Subjects -Fed State
The purpose of this study is to compare the bioavailability (rate and extent of absorption) of two tansulosine 0,4 mg capsule formulations.
- Trial name
- BET04cap (NCT01338623)
- Testing
- Tansulosine
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Biocinese
Intraoperative Floppy Iris Syndrome, Cataract
Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome (IFIS) is a potentially serious cataract surgery complication. IFIS is most commonly associated with the chronic use of tamsulosin and other alpha1-adrenergic receptor antagonists prescribed in…
- Conditions
- Intraoperative Floppy Iris Syndrome, Cataract, Age-related Cataract, Adrenergic Receptor Antagonist Adverse Reaction
- Trial name
- NCT06266962
- Testing
- 1% Atropine drops, Epinephrine
- Where
- Czechia
- Volunteers
- 164 people
- Sponsor
- University Hospital Olomouc
Prostatic Hyperplasia, Benign
Transperineal Laser Ablation for Treatment of Benign Prostatic Obstruction
Rationale: With age a large group of men experience lower urinary tract symptoms (LUTS) due to benign prostatic obstruction (BPO). Standard treatment is a transurethral resection of the prostate or laser vaporization.
- Trial name
- NCT03653117
- Testing
- Transperineal laser ablation
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Prostatic Hyperplasia
Study to Compare the Efficacy and Safety of Combination Treatment With Dutasteride and Tamsulosin With Tamsulosin Monotherapy, in Men With Moderate to Severe Benign Prostatic Hyperplasia
This is a multicentre, randomised, double-blind, parallel group study in Asian subjects. The aim of the study is to investigate whether combination therapy with dutasteride and tamsulosin is more effective than tamsulosin…
- Trial name
- NCT02058368
- Testing
- Dutasteride 0.5mg capsules, Tamsulosin 0.2mg tablets
- Where
- 46 sites in China, Japan and 2 more
- Volunteers
- 607 people
- Sponsor
- GlaxoSmithKline
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Evaluation of the Safety, Tolerability, and Efficacy of the Omega System for the Treatment of LUTS Due to BPH
This is a prospective, two-stage, multi-center, pilot clinical study to evaluate the safety/tolerability/efficacy of the Omega System device.
- Trial name
- Omega (NCT05757687)
- Testing
- Omega device
- Where
- 5 sites in Georgia
- Volunteers
- 11 people
- Sponsor
- ProArc Medical
Bladder Outlet Obstruction, Lower Urinary Tract Symptoms
The Value of Multiple Urine Flow Rate Measurements in Male Benign Prostatic Hyperplasia (BPH) Subjects
Crossover comparison of different flow meters with a digital home flow meter as a reference. Main hypothesis: Reapeated home flow measurements with a disposable device will provide a better understanding of the patients urinary…
- Trial name
- NCT00710749
- Testing
- Disposable device, Digital device, Clinic flow measurement
- Where
- 4 sites in United States, Netherlands and 2 more
- Volunteers
- 60 people
- Sponsor
- Wellspect HealthCare
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
MCS in the Treatment of Lower Urinary Tract Symptoms
The hypothesis of the study is to examine whether MCS-2 is safe and effective in the treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia.
- Trial name
- MCS_LUTS (NCT01002417)
- Testing
- MCS-2 15 mg/day, MCS-2 30 mg/day
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Health Ever Bio-Tech Co., Ltd.