Clinical trials: Prostatic Hyperplasia
Benign Prostate Hypertrophy(BPH), LUTS(Lower Urinary Tract Symptoms)
MISTER Study: Minimally Invasive Steam Therapy - Russian Effectiveness Registry
Rezūm is a minimally invasive procedure that uses water vapor (steam) to treat urinary symptoms caused by an enlarged prostate (benign prostatic hyperplasia, BPH).
- Trial name
- MISTER (NCT07723378)
- Testing
- Rezūm
- Where
- Russia
- Volunteers
- 1,400 people
- Sponsor
- Sechenov University
Benign Prostatic Hyperplasia
A Clinical Study to Evaluate the Safety and Efficacy of the FloStent in Men With Benign Prostatic Hyperplasia Symptoms
The goal of this study is to determine the safety and effectiveness of the FloStent, a medical device used to treat men with symptoms of Benign Prostatic Hyperplasia, compared to sham (procedure without deployment of the…
- Trial name
- RAPID-III (NCT06849258)
- Testing
- FloStent
- Where
- 20 sites in United States, Australia
- Volunteers
- 215 people
- Sponsor
- Rivermark Medical
Benign Prostate Hyperplasia, Erectile Dysfunction
A Study of Tadalafil in Men With Benign Prostatic Hyperplasia (BPH) and Erectile Dysfunction (ED)
The purpose of this study is to see whether tadalafil can reduce the signs and symptoms in men with Erectile Dysfunction (ED) and Benign Prostatic Hyperplasia-Lower Urinary Tract Symptoms (BPH-LUTS) and improve their quality of…
- Trial name
- NCT01937871
- Testing
- 5 mg Tadalafil, 0.2 mg Tamsulosin
- Where
- 14 sites in China
- Volunteers
- 909 people
- Sponsor
- Eli Lilly and Company
Benign Prostatic Hyperplasia
(Phosphodiesterase 5 Inhibitors & α-blockers): Single Versus Combined Therapy in Benign Prostatic Hyperplasia
To compare between efficacy of phosphodiesterase5 inhibitors (tadalafil 5 mg) and Alpha Blockers (tamsulosin 0.4 mg) monotherapy vs combined therapy in treatment of lower urinary tract symptoms of benign prostatic hyperplasia.
- Trial name
- NCT05236634
- Testing
- Phosphodiesterase 5 Inhibitors, Alpha Blockers, Combined Alpha Blockers and Phosphodiesterase 5 Inhibitors
- Volunteers
- 120 people
- Sponsor
- Assiut University
Benign Prostatic Hypertrophy With Outflow Obstruction, Benign Prostatic Hyperplasia
Clinical Results of Odyliresin (Iresine Celosia) in Symptomatic Benign Prostatic Hyperplasia
Odyliresin (Iresine Celosia) is a cytochrome-flavoprotein with a powerful anti-oxydant action on cells, has a therapeutic effect on BPH-related LUTS, reducing symptoms, prostate volume, improving the patient's quality of life and…
- Trial name
- Odyliresin (NCT02977832)
- Testing
- Odyliresin, Alfuzosin
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Study of Solifenacin Succinate and Tamsulosin Hydrochloride OCAS in Males With Lower Urinary Tract Symptoms
Clinical study to examine the efficacy, safety and tolerability of combination therapy of tamsulosin hydrochloride and solifenacin succinate compared to monotherapy of tamsulosin hydrochloride in the treatment of males with LUTS…
- Trial name
- Neptune (NCT01018511)
- Testing
- tamsulosin hydrochloride OCAS 0.4 mg, tamsulosin hydrochloride/solifenacin succinate fixed dose combination (0.4 mg/6 mg)
- Where
- 118 sites in Austria, Belarus and 11 more
- Volunteers
- 1,334 people
- Sponsor
- Astellas Pharma Europe B.V.
Overactive Bladder, Benign Prostatic Hyperplasia
Efficacy And Safety Of Combination Therapy For Treatment Of Overactive Bladder In Male Patients With Benign Prostatic Hyperplasia.
The purpose of this study is to investigate the safety and efficacy of combination therapy involving β3-adrenoceptor agonist, mirabegron, and α-blockers for the treatment of OAB symptoms in male patients with BPH.
- Trial name
- NCT02279615
- Testing
- Mirabegron, Tamsulosin
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
Anterior Bridge-Preserving Versus Conventional Early Apical Release in Bipolar Enucleation of the Prostate
Bipolar enucleation of the prostate is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Obstruction, Stress Urinary Incontinence (SUI), Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
- Trial name
- ABPS-EAR-BIPO (NCT07893548)
- Testing
- Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), Conventional Early Apical Release (EAR)
- Volunteers
- 230 people
- Sponsor
- Benha University
Benign Prostate Hyperplasia
Safety and Pharmacokinetic Interaction Study of Tadalafil and Dutasteride
This is an open-label, two-arm, one-sequence, cross-over study to evaluate the safety and pharmacokinetic interaction after oral concomitant administration of tadalafil and dutasteride in healthy male volunteers.
- Trial name
- NCT01942551
- Testing
- Tadalafil, Dutasteride
- Where
- South Korea
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Dongkook Pharmaceutical Co., Ltd.
Benign Prostatic Hyperplasia
Study of Tadalafil Once-a-Day for 12 Weeks in Japanese Men With Benign Prostatic Hyperplasia Followed by an Open-Label Extension
This study is a randomized, double-blind, placebo-controlled, parallel-design to compare the efficacy and safety of tadalafil once-a-day dosing versus placebo for 12 weeks followed by an open-label extension to evaluate the…
- Trial name
- NCT00783094
- Testing
- Tadalafil 2.5 mg, Tadalafil 5 mg
- Where
- 6 sites in Japan
- Volunteers
- 422 people
- Sponsor
- Eli Lilly and Company
Benign Prostatic Hyperplasia
Local Anesthesia With Schelin Catheter in Rezum Treatment: a Randomized Controlled Trial
In a pilot study, water vapor therapy (RezumTM, Boston Scientific Corporation, Marlborough, MA) was proposed as a minimally invasive procedure for benign prostatic hyperplasia, but often requiring oral ± intravenous sedation or a…
- Trial name
- LOCALVAPOR (NCT06657872)
- Testing
- water vapor therapy under general anesthesia, water vapor therapy under local anesthesia
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Benign Prostatic Hyperplasia
Study to Investigate the Efficacy and Safety of GL2702 GLARS-NF1tablet and Harnal-D - Tablet in BPH Patients With LUTS
Study to investigate the efficacy and safety of GL2702 GLARS-NF1tablet and Harnal-D - tablet in benign prostatic hyperplasia patients with lower urinary tract symptomatic
- Trial name
- GL2702 (NCT02303769)
- Testing
- Tamsulosin HCL 0.4mg, Tamsulosin HCL 0.2mg
- Where
- South Korea
- Volunteers
- 309 people
- Sponsor
- GL Pharm Tech Corporation
Lower Urinary Tract Symptoms (LUTS), BPH (Benign Prostatic Hyperplasia)
Transcutaneous Tibial Nerve Stimulation (TTNS) Patch in the Treatment of Patients With Lower Urinary Tract Symptoms (LUTS) After Benign Prostatic Hyperplasia (BPH) Surgery
The incidence of lower urinary tract symptoms (LUTS) with persistent overactive bladder (OAB) symptoms after benign prostatic hyperplasia (BPH) surgery ranges from approximately 5% to 35%, meaning that roughly one-third of…
- Trial name
- NCT07710794
- Testing
- Transcutaneous Tibial Nerve Stimulation (TTNS), Behavioral Treatment
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Qilu Hospital of Shandong University
Prostatic Hyperplasia
Study to Evaluate the Therapeutic Action of Tamsulosin and Finasteride in Symptomatic Benign Prostatic Hyperplasia (BPH) Patients
Study to evaluate the therapeutic effect of tamsulosin and finasteride in symptomatic BPH patients, two medications indicated in BPH belonging to two different pharmacological classes, as evaluated from the point of view of…
- Trial name
- NCT02244229
- Testing
- Tamsulosin, Finasteride
- Volunteers
- 403 people
- Sponsor
- Boehringer Ingelheim
Prostatic Hyperplasia, Surgery
EEAP Using Moses 2.0 Technology vs the Thulium Fiber Laser in Medium-Large Prostates
Introduction: Endoscopic anatomical enucleation of the prostate (EEAP) with lasers has emerged as an effective and less invasive surgical option compared to traditional methods.
- Conditions
- Prostatic Hyperplasia, Surgery, Endoscopic Anatomical Enucleation of the Prostate (EEAP)
- Trial name
- NCT06565741
- Testing
- MoLEP, ThuFLEP
- Where
- 3 sites in Spain
- Volunteers
- 120 people
- Sponsor
- Fundacio Puigvert
Prostatic Hyperplasia
Establishing the Benefits of Adherence to Enlarged Prostate Treatment: A Validation Study Linking Adherence to Outcomes Using the Market Scan Database
Adherence and length of therapy with 5-alpha reductase inhibitor (5ARI) treatment may be associated with improved clinical outcomes of enlarged prostate (EP) as well as lower health care costs.
- Trial name
- NCT01381510
- Testing
- 5-alpha Reductase Inhibitor (5ARI)
- Volunteers
- 54,459 people
- Sponsor
- GlaxoSmithKline
Prostatic Neoplasms, Digital Rectal Examination
Learning Curve of Digital Rectal Examination for Prostate Cancer Among Internship
The investigators conduct this prospective study to investigate the learning curve of digital rectal examination (DRE) for prostate cancer among internship.
- Conditions
- Prostatic Neoplasms, Digital Rectal Examination, Benign Prostatic Hyperplasia
- Trial name
- NCT03479359
- Testing
- Routine review of DRE results by attending doctors
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Changhai Hospital
Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection, Benign Prostatic Hyperplasia With Outflow Obstruction
Bipolar Resection vs Enucleation of Prostate
The aim of this study is to evaluate efficacy and safety of transurethral resection of the prostate and bipolar enucleation of the prostate.
- Conditions
- Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection, Benign Prostatic Hyperplasia With Outflow Obstruction, Benign Prostatic Hyperplasia With Symptomatic Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
- Trial name
- TURP vs BiTUEP (NCT06983444)
- Testing
- TURP, TUEP
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- South Valley University
Prostatic Hyperplasia
Efficacy and Safety of SL77.0499-10 (Alfuzosin) Versus Placebo and Tamsulosin in Japanese Patients With Benign Prostatic Hyperplasia
The primary objective of the study is to demonstrate the superiority of SL77.0499-10 10mg once daily over placebo and the non-inferiority versus tamsulosin hydrochloride after 12 weeks treatment in terms of the efficacy in…
- Trial name
- NCT00399464
- Testing
- alfuzosin
- Where
- Japan
- Volunteers
- 1,177 people
- Sponsor
- Sanofi
Prostate, Benign Prostatic Hyperplasia (BPH)
Inverted-T Incision With Early Apical Release vs. Three-Lobe in Holmium Laser Enucleation of The Prostate
Aim of the work is to compare the surgical efficacy and perioperative outcomes of the inverted-T incision with early apical release technique versus the standard three-lobe technique in patients undergoing Holmium Laser…
- Trial name
- NCT07642063
- Testing
- inverted-T with early apical release technique, standard three-lobe technique
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Benha University