Clinical trials: Prostatic Obstruction
Anesthesia, Anesthesia Complication
Sedation Complications in Urology During Spinal Anesthesia With Dexmedetomidine or Midazolam Regarding OSA Risk
Light to moderate sedation is recommended during surgery with spinal anesthesia . This study is exploring which sedation drug is better, midazolam or dexmedetomidine for transurethral resection of bladder and prostate in patients…
- Conditions
- Anesthesia, Anesthesia Complication, Osa Syndrome, Transurethral Resection of Prostate
- Trial name
- NCT04817033
- Testing
- Spinal anesthesia with intraoperative dexmedetomidine sedation, Spinal anesthesia with intraoperative midazolam sedation, Dexmedetomidine
- Where
- Croatia
- Volunteers
- 115 people
- Sponsor
- University Hospital of Split
Bladder Neoplasm, Prostatic Neoplasms
Preventing Catheter Related Bladder Discomfort (CRBD) With Bilateral Pudendal Nerve Block
Bladder irrigation with a 3 way foley catheter is an important component of post operative management of transurethral bladder surgeries. But it is associated with a high incidence of bladder discomfort.
- Trial name
- NCT05022160
- Testing
- pudendal nerve block
- Where
- Pakistan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Armed Forces Hospital, Pakistan
Overactive Bladder
This is a Prospective, Randomized, Double-Blind Study Comparing Intravesical Injection of Botox® to Placebo.
The current study will investigate the comparative efficacy, safety and patient satisfaction of intradetrusor injections BOTOX® injections (200U) versus placebo (saline) injections in the treatment of OAB secondary to benign…
- Trial name
- BTX0621 (NCT00479596)
- Testing
- Botox
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Urological Sciences Research Foundation
BPH With Urinary Obstruction, Male
HoLEP vs BPRP of a Large Volume BPH: a Randomised Controlled Trial
To compare bipolar resection versus holmium laser enucleation for management of large BPH.
- Trial name
- NCT04143399
- Testing
- holmium laser enucleation of the prostate, Bipolar resection of the prostate
- Where
- Egypt
- Volunteers
- 145 people
- Sponsor
- Cairo University
Benign Prostatic Hyperplasia, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Feasibility and Utility of a Prehabilitation Program for Use in Patients With Benign Prostatic Hyperplasia Who Have Elected to Undergo Holmium Laser Enucleation of the Prostate (HoLEP).
Benign prostatic hyperplasia (BPH) is a debilitating condition which is highly prevalent in older males, up to 45% of those over the age of 45 are affected and 80% of those over the age of 70 are affected.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia With Outflow Obstruction
- Trial name
- NCT07552961
- Testing
- Comprehensive Prehabilitation Programming
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms
Ejaculation-Preserving Versus Conventional Dual Wavelength Diode Laser Vaporization of the Prostate
Surgery to relieve urinary blockage caused by an enlarged prostate works well, but most men lose antegrade ejaculation afterwards, because semen passes backwards into the bladder instead of forwards.
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms, Bladder Outlet Obstruction
- Trial name
- EP-TUVP (NCT07777068)
- Testing
- Conventional dual-wavelength diode laser vaporization of the prostate, Ejaculation-preserving dual wavelength diode laser vaporization of the prostate
- Where
- Iraq
- Volunteers
- 119 people
- Sponsor
- ALI KAMAL M. SAMI
Prostate Cancer
Stellate Ganglion Block for Hot Flushes in Men Treated With ADT
Androgen deprivation therapy (ADT) is widely used as standard therapy in the treatment of locally advanced and metastatic prostate cancer. Hot flushes and night sweats are one of the main side-effects of ADT.
- Trial name
- NCT02295163
- Testing
- Stellate ganglion block
- Where
- Netherlands
- Sponsor
- Rijnstate Hospital
Urinary Obstruction
The Importance of Non-invasive Methods in the Diagnosis of Lower Urinary System Symptoms.
The diagnosis of bladder outlet obstruction is made by pressure-flow studies, which is an invasive method. This study was conducted to evaluate non-invasive, effective, and low-cost diagnostic methods in male patients with…
- Trial name
- NCT04870749
- Testing
- IPP,IPSS,VPSS
- Where
- Turkey (Türkiye)
- Volunteers
- 219 people
- Sponsor
- Cumhuriyet University
Acute Urinary Retention, Benign Prostatic Hyperplasia
Tamsulosin With or Without Tadalafil for Trial Without Catheter After Acute Urinary Retention Due to Benign Prostatic Hyperplasia
Acute urinary retention is a common emergency in men with benign prostatic hyperplasia. After bladder drainage with a urethral catheter, patients usually undergo a trial without catheter to determine whether they can pass urine…
- Conditions
- Acute Urinary Retention, Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
- Trial name
- TAMS-TAD-TWOC (NCT07654413)
- Testing
- Tamsulosin, Tadalafil
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Beni-Suef University
Nocturnal Polyurea in Patients With BPH
Adding Desmopressin to Tamsulosin for Treatment of BPH
In this study investigators will add desmopressin for treatment of patients with benign prostatic hyperplasia and nocturnal polyurea
- Trial name
- NCT05945420
- Testing
- Desmopressin Acetate
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Impact of 80 W KTP Laser Vaporization Prostatectomy on Severity of Obstruction in Benign Prostatic Hyperplasia
The purpose of this study is to compared the efficacy of 80W KTP photoselective laser vaporization prostatectomy (PVP) and transurethral resection of the prostate (TURP) in reducing the volume of prostate and relieving the…
- Trial name
- NCT00908427
- Testing
- photoselective vaporization prostatectomy (PVP), Transurethral resection of the prostate
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Samsung Medical Center
BPH With Symptomatic Lower Urinary Tract Symptoms, BPH With Urinary Obstruction
Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate
Many consider laser enucleation of the prostate the new 'gold standard' for the surgical treatment of benign prostatic hyperplasia (BPH) due to its excellent outcomes, high success rates, and long-term efficacy.
- Trial name
- NCT07187180
- Testing
- holmium laser, pulsed thulium laser
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Smita De
TURP(Transurethral Resection of Prostate)
Sacral Erector Spinae Plane Block in Transurethral Prostate Resection Surgery
The aim of this study is to investigate the effects of bilateral sacral erector spinae plane block on hemodynamic values, postoperative pain, analgesic use and patient satisfaction during operative period in Transurethral…
- Trial name
- NCT06962085
- Testing
- sacral erector spinae plane block group, Opioid Analgesics
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Adiyaman University
Acute Post-operative Pain, Nerve Block
Comparison of Analgesia Efficacy of Transversus Abdominis Plane Block and Posterior Approach Quadratus Lumborum Block
Prostate cancer is the second most common cancer and the fifth in cancer-related deaths. Open radical retropubic prostatectomy is the most common surgical treatment for localized prostate cancer.
- Conditions
- Acute Post-operative Pain, Nerve Block, Prostate Cancer
- Trial name
- NCT06075498
- Testing
- transversus abdominis plane block,
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Muğla Sıtkı Koçman University
Disorder of the Lower Urinary Tract
Changes of microRNA Expression in Obstructive and Neurogenic Bladder Dysfunction
Patients with obstructive or neurogenic lower urinary tract disease will be invited to participate. Upon agreement they will undergo an assessment of bladder function (questionnaires) and bladder biopsies at 2 time-points.
- Trial name
- MoVe (NCT02410876)
- Testing
- Bladder biopsy, Urodynamic study
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Overactive Bladder Syndrome, Bladder Outlet Obstruction
Urodynamics and Clinical Factors That Are Associated With Bladder Over-sensitivity
Urodynamic examination evaluates storage and empting phases of the urinary bladder. It enables the clinician to correlate physiologic findings to patients' complains.
- Conditions
- Overactive Bladder Syndrome, Bladder Outlet Obstruction, Benign Prostate Enlargement, Stress Incontinence (Female) (Male)
- Trial name
- NCT03486639
- Testing
- IPSS questionnaire
- Where
- Israel
- Volunteers
- 330 people
- Sponsor
- Assaf-Harofeh Medical Center
Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Registry of MIUS for Benign Prostatic Obstruction
This national, multicenter, prospective registry aims to collect standardized perioperative and follow-up data on patients undergoing minimally invasive surgical management for benign prostatic obstruction (BPO) in Turkey.
- Trial name
- ReMIUS-BPO (NCT07159165)
- Testing
- Minimally invasive surgical treatment for benign prostatic obstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people
- Sponsor
- Ondokuz Mayıs University
Prostate Cancer
Laparoscopic TAP Block During Robotic Assisted Laparoscopic Radical Prostatectomy for Improvement in Postoperative Pain
Determine the impact of a laparoscopic-guided transversus abdominis plane (TAP) block timing (at initiation or conclusion of procedure) on the postoperative pain experience in patients following robot assisted laparoscopic…
- Trial name
- TAPBlock (NCT05753046)
- Testing
- Early TAP Block, Late TAP Block
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Corewell Health East
Prostate Biopsy
Pain and Anxiety During Transrectal Prostate Biopsy
Many studies have been conducted in the literature to manage pain and anxiety levels for patients undergoing transrectal prostate biopsy.
- Trial name
- NCT05358223
- Testing
- Music, TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Zonguldak Bulent Ecevit University
Prostate CA
Evaluation of Addition of Dexamethasone to Transversus Abdominis Plane (TAP) Peripheral Nerve Block
Transversus abdominis plane (TAP) blocks are increasingly being performed after abdominal surgery to provide post operative analgesia.
- Trial name
- NCT01303003
- Testing
- Dexamethasone, TAP block
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.