Clinical trials: Prostheses-related Infections, open to volunteers
Device Related Infection, Vascular Access Complication
The IVCare Adaptive Platform Trial
The IVCare trial is a multicentre adaptive platform study evaluating interventions to prevent infections and other complications associated with central venous access devices (CVADs) in patients with newly inserted or existing…
- Conditions
- Device Related Infection, Vascular Access Complication, Device Related Sepsis, Catheter Infection
- Trial name
- NCT07587593
- Testing
- Connectors/Caps Domain - Standard of Care, Curos™, ClearGuard™ HD
- Volunteers
- 2,500 people
- Sponsor
- The University of Queensland
Revision Hip Arthroplasty, Aseptic Loosening of Prosthetic Joint
Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Revision Hip Prosthesis System
This is a multicenter, prospective, observational, post-market clinical follow-up (PMCF) study designed to evaluate the safety and clinical performance of the Tipmed™ Revision Hip Prosthesis System in adult participants…
- Conditions
- Revision Hip Arthroplasty, Aseptic Loosening of Prosthetic Joint, Prostheses-related Infections, Joint Instability
- Trial name
- NCT07653295
- Testing
- Tıpmed™ Revision Hip Prosthesis System
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- TIPMED Medical Device Manufacturing Ltd. Co.
Prosthesis-Related Infections
PCA Loading Time Before Knee Prosthetic Joint Infection Revision
Proof of principle pilot study of the effect of dietary nutritional loading of protocatechunic acid (PCA) on the health and welfare of individuals with prosthetic joint infection (PJI), as measured by standard biomarkers
- Trial name
- NCT06591728
- Testing
- Oral PCA
- Volunteers
- 10 people
- Sponsor
- Dr. Dean Reeves Clinic
Incisional Hernia, Ventral Hernia
Risk Factors for Mesh Infection After Abdominal Wall Reconstruction
Abdominal wall reconstruction (AWR) with mesh is the standard repair for ventral, incisional, parastomal and complex abdominal wall defects, but mesh-related infection remains one of its most serious complications - prolonging…
- Conditions
- Incisional Hernia, Ventral Hernia, Parastomal Hernia, Abdominal Wall Defect
- Trial name
- NCT07725718
- Where
- Egypt
- Volunteers
- 420 people
- Sponsor
- Minia University
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Hydrocephalus, Ventriculoperitoneal Shunt Infection
Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different Etiologies
Objectives Primary: To measure the reduction in VP shunt infection rates using topical vancomycin powder. Secondary: To compare efficacy across different Etiological Strata (Congenital, Post-hemorrhagic, post-inflammatory).
- Conditions
- Hydrocephalus, Ventriculoperitoneal Shunt Infection, Surgical Site Infection (SSI), Cerebrospinal Fluid Shunt Infection
- Trial name
- NCT07547826
- Testing
- Topical Vancomycin Powder, Standard Perioperative Care
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Assiut University
Vascular Access Complication, Device Related Infection
Chlorhexidine Caps for CLABSI Prevention in Hemodialysis: a Pilot Randomized Controlled Trial
The goal of this clinical trial is to compare a chlorhexidine antimicrobial barrier cap in patients requiring hemodialysis treatment to the standard hemodialysis caps currently used within the Metro North Kidney Health Service.
- Conditions
- Vascular Access Complication, Device Related Infection, Device Related Sepsis, Catheter Infection
- Trial name
- ECHO-HD (NCT07019610)
- Testing
- ClearGuard HD, B Braun Combi-stopper
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- The University of Queensland
Implant Infection, Skeletal Sarcoma
Implant-Related Infections in Patients With Skeletal Sarcomas
The aim of this observational study is to gain knowledge on the microbial and immunological factors behind implant-related infections in patients with skeletal sarcoma.
- Conditions
- Implant Infection, Skeletal Sarcoma, Hip Arthritis, Prosthesis-Related Infections
- Trial name
- IRISSAR (NCT07264296)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Cardiac Disease, Device Related Infection
Application of Radiomics for Diagnosis and Follow-up of Cardiovascular Device Infections: PREDICT Study
Single center, open-label, phase IV clinical trial to study the application of radiomics in molecular imaging for diagnosis and follow-up of CVDIs.
- Trial name
- PREDICT (NCT07454096)
- Testing
- PET/CT imaging
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica