Clinical trials: Prosthesis-Related Infections
Vascular Access Complication, Device Related Infection
Novel Antimicrobial Dressing in Peripheral Intravenous Catheters (PIVCs)
The goal of this clinical trial is to compare a chlorhexidine impregnated dressing for peripheral intravenous catheters (PIVCs) to the standard dressing currently used in general medical and surgical inpatient wards.
- Conditions
- Vascular Access Complication, Device Related Infection, Device Related Sepsis, Device Site Reactions
- Trial name
- ProP (NCT05741866)
- Testing
- Chlorhexidine gluconate impregnated bordered polyurethane dressing, Standard bordered polyurethane dressing
- Where
- 3 sites in Australia, France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Fractures, Bone, Infection, Bacterial
Gut Microbiome of Patients Undergoing Antibiotic Therapy for Orthopedic Device-related Infection
The microbiome of 80 orthopedic-device related infection (ODRI) patients treated with antibiotics and 10 healthy controls will be investigated. Samples (blood, stool, saliva, skin-swab) are collected 4x within 6 months.
- Conditions
- Fractures, Bone, Infection, Bacterial, Joint Infection, Bone Infection
- Trial name
- IMPAT-ODRI (NCT04440631)
- Testing
- no intervention, observational only
- Where
- 2 sites in Switzerland
- Volunteers
- 12 people
- Sponsor
- AO Research Institute Davos
Prosthesis-Related Infections
Dosing of Antibiotics During Reimplantation of Infected Knee and Hip Prostheses
The purpose of the study is to evaluate the concentrations of antibiotics used as empirical treatment in serum and periprosthetic tissues during reimplantation of infected hip and knee prostheses
- Trial name
- DOSOS (NCT02860767)
- Where
- 5 sites in France
- Volunteers
- 30 people
- Sponsor
- Tourcoing Hospital
Pacemaker Complication, Infections
Impact of Partial Capsule Decortication on Device-related Infection in Patients Receiving Cardiac Implantable Electronic Device Replacement
Increasing number of cardiac implantable electronic devices (CIEDs) have been implanted in the worldwide every year, which is accompanied by the growing number of CIED-related infection, especially in patients with CIED…
- Trial name
- STERILE (NCT05390216)
- Testing
- Partial capsule decortication
- Where
- China
- Volunteers
- 1,016 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Infection, Driveline Heart-assisted Device Related Infection
Postoperative Infections and Immune Profiles in Patients Undergoing LVAD Implantation
The objective of this study is to investigate the incidence of infection and changes in the immune profile following left ventricular assist device implantation.
- Conditions
- Infection, Driveline Heart-assisted Device Related Infection, Pneumonia, Sepsis
- Trial name
- NCT07255716
- Testing
- none intervention
- Where
- China
- Volunteers
- 120 people
- Sponsor
- China National Center for Cardiovascular Diseases