Clinical trials: Prosthetic Complication, open to volunteers
Infections Joint Prosthetic, Overweight or Obesity
Antibiotic Prophylaxis in High-Risk Arthroplasty Patients
To determine the effectiveness of a 7-day course of an oral, prophylactic antibiotic on the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk…
- Conditions
- Infections Joint Prosthetic, Overweight or Obesity, MSSA Colonization, MRSA
- Trial name
- NCT04297592
- Testing
- Cephalexin, Doxycycline, Cefadroxil
- Where
- 2 sites in United States
- Volunteers
- 4,618 people
- Sponsor
- Mayo Clinic
Complete Edentulism
Prosthetic Complications in Full-arch Screw-retained Implant Restorations Using Monolithic Zirconia Versus Titanium Frameworks: A Randomized Clinical Trial
The goal of this clinical trial is to to compare the prosthetic complication rate and Oral Health-Related Quality of Life (OHRQoL) between screw-retained monolithic zirconia frameworks and CNC-milled titanium frameworks with…
- Trial name
- NCT07657364
- Testing
- Monolithic Zirconia Prosthesis, CNC-milled titanium framework and zirconia superstructure
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Cairo University
Prosthetic-joint Infection, Knee Infection
Real-component vs All-cement Articulating Spacers for Periprosthetic Knee Infection
In the US, if an infection in an artificial knee joint doesn't heal with antibiotics alone, the standard treatment is a two-stage revision of the artificial knee.
- Conditions
- Prosthetic-joint Infection, Knee Infection, Arthroplasty Complications, Joint Infection
- Trial name
- NCT06293352
- Testing
- All-cement articulating spacer, Durable, real-component articulating spacer, Rigid Spacer
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Northwestern University
Peri-Implant Health, Implant Complication
Influence of Zirconia Abutments on Peri-Implant Tissues in Single-Tooth Restorations
Objectives: To compare the influence of pre-fabricated titanium abutments and customized milled zirconia abutments on implant biocompatibility and the peri-implant region, as well as on radiographic bone loss and oral…
- Conditions
- Peri-Implant Health, Implant Complication, Prosthesis and Implants
- Trial name
- NCT07456163
- Testing
- Pre-fabricated standardized titanium abutments, Customized anatomical zirconia abutments
- Where
- Brazil
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Revision Hip Arthroplasty, Aseptic Loosening of Prosthetic Joint
Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Revision Hip Prosthesis System
This is a multicenter, prospective, observational, post-market clinical follow-up (PMCF) study designed to evaluate the safety and clinical performance of the Tipmed™ Revision Hip Prosthesis System in adult participants…
- Conditions
- Revision Hip Arthroplasty, Aseptic Loosening of Prosthetic Joint, Prostheses-related Infections, Joint Instability
- Trial name
- NCT07653295
- Testing
- Tıpmed™ Revision Hip Prosthesis System
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- TIPMED Medical Device Manufacturing Ltd. Co.
Prosthetic-joint Infection, Dysbiosis
Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee
Prosthetic joint infection (PJI) is one of the most devastating complications following total joint arthroplasty (TJA) of the hip and knee. Standard of care (SOC) treatment includes surgery and antimicrobials.
- Trial name
- NCT06636669
- Testing
- Probiotic, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 152 people
- Sponsor
- Boston Medical Center
Structural Valve Deterioration, Structural Valve Degeneration
The ReTAVI Prospective Observational Registry
Patients with severe aortic stenosis (sAS) treated with transcatheter aortic valve implantation (TAVI) (increasingly younger \& lower risk pts) are experiencing SVD of the index THV and thus developing an indication for a…
- Conditions
- Structural Valve Deterioration, Structural Valve Degeneration, Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure, Prosthetic Valve Malfunction
- Trial name
- NCT05601453
- Testing
- Elective redo transcatheter aortic valve implantation (redo-TAVI)
- Where
- 62 sites in Austria, Canada and 9 more
- Volunteers
- 250 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Alveolar Bone Atrophy, Alveolar Bone Grafting
Digital Planning and Clinical Assessment of the Treated Atrophic Posterior Maxilla With a Sinus Lift Procedure: a Cross-sectional Study.
Maxillary posterior area is the most challenging site for dental implant placement. Indeed, complex remodeling processes, resulting in changes of the maxillary sinus and shape of the alveolar ridge will cause difficulties in…
- Conditions
- Alveolar Bone Atrophy, Alveolar Bone Grafting, Peri-Implant Health, Sinus Floor Augmentation
- Trial name
- NCT07526337
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Arthroplasty Complications
Are Elastic Restraints Still Necessary in Improved Rehabilitation Programs After Hip and Knee Prosthetic Surgery?
Venous thrombosis and pulmonary embolism are considered serious and potentially preventable complications of hip and knee replacement surgery.
- Trial name
- NCT06563531
- Testing
- Pharmacological thromboprophylaxis and elastic compression, Pharmacological thromboprophylaxis without elastic compression
- Where
- France
- Volunteers
- 1,274 people
- Sponsor
- Clinique Pasteur Lanroze
Prosthesis-Related Infections
PCA Loading Time Before Knee Prosthetic Joint Infection Revision
Proof of principle pilot study of the effect of dietary nutritional loading of protocatechunic acid (PCA) on the health and welfare of individuals with prosthetic joint infection (PJI), as measured by standard biomarkers
- Trial name
- NCT06591728
- Testing
- Oral PCA
- Volunteers
- 10 people
- Sponsor
- Dr. Dean Reeves Clinic
Periprosthetic Fracture of the Upper or Lower Limb, Peri-implant Fracture of the Upper or Lower Limb
Peri-Implant and Peri-Prosthetic Fractures: Epidemiology, Morbidity, Mortality, Treatment and Outcome Analysis
This study supports Spanish data collection and analysis on Periprosthetic and Peri-implant fractures of the upper and lower limb. Treatment and clinical management of this fractures are complex and goes along with complications.
- Conditions
- Periprosthetic Fracture of the Upper or Lower Limb, Peri-implant Fracture of the Upper or Lower Limb, Periprosthetic Fractures, Peri-implant Fracture
- Trial name
- PIPPAS (NCT04663893)
- Where
- 7 sites in Spain
- Volunteers
- 2,500 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Biting Forces, Bone; Change, Diabetic (Manifestation)
Evaluation Of Marginal Bone Height Changes And Biting Force In Screw Retained Implant Prostheses Using Reinforced Resin Vs Monolithic Zirconium
This studies aims to compare the behavior of recently introduced resin reinforces compared to monolithic zirconia
- Conditions
- Biting Forces, Bone; Change, Diabetic (Manifestation), Color Stability, Disorder of Soft Tissue
- Trial name
- NCT07007572
- Testing
- Digitally-fabricated implant supported supra-structure fabricated from reinforced resin, Digitally-fabricated implant supported supra-structure fabricated from monolithic zirconia
- Where
- 2 sites in Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Metastases
Analysis of Intramedullary Nail and Prosthetic Reconstruction After Surgical Treatment of Bone Metastases of Proximal Femur
The investigators will collect data of patients treated surgically for impending or pathological fracture of the proximal femur due to bone metastases between 01/01/2000 and 31/12/2023 with IMN or THA or HHA or MegaTHA or Mega.
- Trial name
- NCT06918860
- Testing
- Analysis
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Costantino Errani
Pocket Depth, Attachment Loss
Clinical and Microbiological Outcomes of Dental Implants After 10-22 Years of Function
Aim: the aim of this retrospective study is to present long-term data (10+ years of functional loading) on the success and survival of ZimVie (3i) implants.
- Conditions
- Pocket Depth, Attachment Loss, Bone Loss in Jaw
- Trial name
- NCT06803576
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Incisional Hernia, Ventral Hernia
Risk Factors for Mesh Infection After Abdominal Wall Reconstruction
Abdominal wall reconstruction (AWR) with mesh is the standard repair for ventral, incisional, parastomal and complex abdominal wall defects, but mesh-related infection remains one of its most serious complications - prolonging…
- Conditions
- Incisional Hernia, Ventral Hernia, Parastomal Hernia, Abdominal Wall Defect
- Trial name
- NCT07725718
- Where
- Egypt
- Volunteers
- 420 people
- Sponsor
- Minia University
Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure, Prosthetic Valve Malfunction
Randomized Evaluation for Failed TAVR
REVIVE TAVR is an acronym for the Randomized Evaluation of Valve-In-Valve versus Explantation for failed TAVR. This is a prospective, multicenter, global randomized trial investigating the safety and efficacy of reintervention…
- Conditions
- Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure, Prosthetic Valve Malfunction, Prosthesis Failure
- Trial name
- REVIVE-TAVR (NCT06400342)
- Testing
- TAVR-explant, Redo-TAVR
- Volunteers
- 264 people
- Sponsor
- Medstar Health Research Institute
Dental Implant, Bruxism
The General Aim is to Implement Clinical Assessment of Overload by Voluntary Bite Force Registration to Enable Future Simple But Precise Risk Assessment to Provide Individualized Treatment Plans.
The general aim of this clinical trial is to implement clinical assessment of overload by bite force registration to enable future simple but precise risk assessment to provide individualized treatment plans.
- Conditions
- Dental Implant, Bruxism, Bite Force, Dental Prosthesis Complication
- Trial name
- Bite force (NCT07266701)
- Testing
- Bite force device. Innobyte Kube Innovation TM, dental radiology
- Where
- Sweden
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Malmö University
Prosthetic Complication, Prosthesis Failure, Dental
New Stereophotogrammetry System to Capture Complete-arch Impression
Patients in need of complete arch restorations will be treated with dynamic navigation system. Once the implants are positioned, a new system of stereophotogrammetry will record the implant positions to capture a precise…
- Trial name
- NCT06745232
- Testing
- FAST MAP
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Scan Time
Scan Time and Prosthetic Complications of Intraoral Scanning Versus Intraoral Photogrammetry for Full-Arch Titanium Framework With Zirconia Overlay Implant Screw-Retained Prostheses
This study aims to evaluate the effect of intra-oral scanning and intra-oral photogrammetry on scan time and prosthetic complications in patients receiving full-arch titanium framework with zirconium overlay implant…
- Trial name
- NCT07446790
- Testing
- Intraoral photogrammetry (IOP), Intraoral scanner (IOS)
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Cairo University