Clinical trials: Protein, open to volunteers
Overweight and Obesity in Adults Receiving GLP-1RA Treatment
Yeast Protein Supplementation and Muscle Preservation During GLP-1RA-Induced Weight Loss
The goal of this clinical trial is to evaluate whether yeast protein supplementation can help preserve lean body mass and muscle function in adults with overweight or obesity receiving GLP-1 receptor agonist-related treatment for…
- Trial name
- NCT07817823
- Testing
- Yeast Protein, Whey Protein, Yeast Protein/Whey Protein Blend (1:1)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Huazhong University of Science and Technology
Multiple Myeloma
VitD3 Supplementation in Patients With Multiple Myeloma
The goal of this clinical trial is to evaluate post-transplant immune reconstitution and lymphocyte recovery as well as the 3-year progression-free survival of patients with multiple myeloma in two treatment arms.
- Trial name
- NCT05846880
- Testing
- Lenalidomide, Maintenance Vitamin D, No maintenance Vitamin D
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Amany Keruakous, MD, MS.
Obesity, Obesity & Overweight
The Role of Autoantibodies Against G-protein Coupled Receptors in Obesity
The purpose of this study is to explore if GPCR-autoantibodies: 1. are pressent in people living with obesity, and are associated with degree of obesity 2. if it is associated with obesity related diseases
- Conditions
- Obesity, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus, Obesity and Obesity-related Medical Conditions
- Trial name
- NCT07542327
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Claus Bogh Juhl
Multiple Myeloma in Relapse, Multiple Myeloma, Refractory
APRIL CAR-T Cell Therapy for Patients With BCMA/TACI Positive Relapsed and/or Refractory Multiple Myeloma
A study of APRIL CAR-T cells therapy for patients with BCMA/TACI positive relapsed and/or refractory multiple myeloma
- Trial name
- NCT04657861
- Testing
- APRIL CAR-T cells
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Zhejiang University
Alcohol-associated Fatty Liver Disease
High-Protein Diet for Improving Alcoholic Fatty Liver Disease
Alcohol-associated liver disease (ALD) is a major cause of mortality from malignant liver diseases, accounting for 47.9% of cirrhosis-related deaths and 30% of liver cancer-related deaths annually.
- Trial name
- HP-AFLD-RCT (NCT07632222)
- Testing
- high protein diet, control diet, perilla peptide dietary group
- Volunteers
- 74 people
- Sponsor
- Li Lab,MD
Respiratory Viral Infections, Influenza
Effect of MxA Guidance on Antiviral Treatment in Respiratory Viral Infections
The goal of this clinical trial is to evaluate the effects of myxovirus resistance protein A (MxA)-guided antiviral treatment on treatment duration and adverse outcomes in adults hospitalized with influenza or COVID-19, compared…
- Conditions
- Respiratory Viral Infections, Influenza, SARS CoV 2 Infection
- Trial name
- NCT07892872
- Testing
- Baseline MxA testing, Serial MxA testing, MxA result feedback and antiviral treatment recommendations
- Where
- China
- Volunteers
- 618 people
- Sponsor
- Capital Medical University
Insulin Sensitivity
mTOR as Mediator of Insulin Sensitivity Study
The study investigates the role of mTOR in mediating enhancement of muscle insulin sensitivity following a single bout of exercise.
- Trial name
- NCT05233722
- Testing
- Exercise, Insulin infusion, Rapamycin
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Lymphoproliferative Disorder, Multiple Myeloma
Understanding the Mechanisms of Clonal and Non-clonal Cytopenia Following CAR-T Therapy for Multiple Myeloma or CD19+ Lymphoproliferative Disorder (LPD)
This clinical trial evaluates the impact of preexisting and therapy-emergent germline and somatic variants on cytopenia in patients with multiple myeloma or CD19 positive lymphoproliferative disorder (LPD) following chimeric…
- Trial name
- NCT06630104
- Testing
- Biospecimen Collection, Bone Marrow Aspiration, Electronic Health Record Review
- Where
- 7 sites in United States
- Volunteers
- 82 people
- Sponsor
- Mayo Clinic
Relapsed/Refractory Multiple Myeloma
LCAR-M61SQ in Treatment of Relapsed/Refractory Multiple Myeloma
A prospective, open-label dose-exploration and expansion study to evaluate the safety, tolerability, pharmacokinetics, and antitumor efficacy characteristics of LCAR-M61SQ in patients with relapsed/refractory multiple myeloma.
- Trial name
- NCT06888752
- Testing
- Cell injection
- Volunteers
- 35 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Quality of Life, Patient Reported Outcome (PRO)
Patient-Reported Outcomes in Allogeneic Stem Cell Transplantation and CAR-T Therapy
3.1. Overview Prospective, multicenter, observational cohort study comparing short-term PROs measured with the HM-PRO between two exposure groups: patients undergoing allogeneic stem cell transplantation (allo-SCT) and patients…
- Conditions
- Quality of Life, Patient Reported Outcome (PRO), Allogeneic Blood and Marrow Transplantation (BMT), CAR T Cell Therapy
- Trial name
- QOL-ONE PRO-CT (NCT07289087)
- Volunteers
- 162 people
- Sponsor
- Associazione Qol-one
Growth
Extensively Hydrolyzed Formula Growth Monitioring Study (GMS)
This is a research study to compare an investigational infant formula against a currently marketed infant formula. An investigational infant formula is one that has never been approved by the United States Food and Drug…
- Trial name
- NCT07513506
- Testing
- Extensively hydrolyzed casein formula (C-eHCF), commercially available, Extensively hydrolyzed casein formula (INV-eHCF)
- Where
- 12 sites in United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Multiple Myeloma
BCMA CAR-T Versus ASCT in Transplant-eligible Patients With Multiple Myeloma
This is a prospective, non-inferiority study comparing VRD±D followed by BCMA CAR-T cell therapy versus VRD±D followed by autologous hematopoietic stem cell transplantation in the treatment of newly diagnosed multiple myeloma…
- Trial name
- CAREMM-006 (NCT06793449)
- Testing
- anti-BCMA CAR-T, ASCT
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Neuroendocrine Tumor
An Investigational Scan ([68Ga] Ga-FAPI-04 PET/CT) for the Imaging of Patients With High-Grade Neuroendocrine Cancer
This early phase I trial determines where and to what degree the tracer [68Ga] Ga-FAPI-04 accumulates in normal and cancer tissues in patients with high grade neuroendocrine cancer.
- Trial name
- NCT07132645
- Testing
- Computed Tomography, Gallium Ga 68-DOTA-FAPI-04, Positron Emission Tomography
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan Rogel Cancer Center
Leukaemia, Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma
Randomised Controlled Trial of Artificial Intelligence-assisted Health Education
With the rapid advancement of biopharmaceutical technology, clinical trials have become the crucial bridge connecting new drugs from the laboratory to clinical application.
- Conditions
- Leukaemia, Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma, Lymphoma
- Trial name
- NCT07305337
- Testing
- Artificial Intelligence Health Education, Artificial health education
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Zhongnan Hospital
Hemophilia A, Musculoskeletal Assessment
Effects of Emicizumab Treatment in Patients With Hemophilia A
The aim of our study is to investigate the effects of emicizumab treatment on the musculoskeletal system in children with hemophilia A.
- Conditions
- Hemophilia A, Musculoskeletal Assessment, Musculoskeletal Abnormalities
- Trial name
- NCT07190118
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Hasan Kalyoncu University
Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma
Using Tumour DNA and Proteins to Better Understand How Pancreatic Cancer Responds to Treatment
The goal of this study is to learn if the genetic information and proteins from tumours can help treat pancreatic ductal adenocarcinoma (PDAC).
- Conditions
- Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma, Borderline Resectable Pancreatic Ductal Adenocarcinoma, Locally Advanced Pancreatic Ductal Adenocarcinoma
- Trial name
- ACCELERATE (NCT06574620)
- Testing
- Genetic testing, Optional biopsy, Tissue collection
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- British Columbia Cancer Agency
Lower Respiratory Tract Infection (LRTI), Pneumonia
Optimising Antibiotic Use for Paediatric Lower Respiratory Tract Infections in Africa
Lower respiratory tract infections (LRTIs) remain a leading cause of hospitalisation and death among young children in Africa. Although viral infections account for a substantial proportion of LRTIs, antibiotics are frequently…
- Conditions
- Lower Respiratory Tract Infection (LRTI), Pneumonia, Bronchopneumonia, Bronchiolitis
- Trial name
- BEACON (NCT07841691)
- Testing
- CRP- and PREPARE-guided Antibiotic Prescription
- Where
- South Africa
- Volunteers
- 400 people
- Sponsor
- University of Witwatersrand, South Africa
Protein Metabolism
Anabolic Response to Beef vs Plant Protein in (Pre)Frail Older Adults Using a Novel Stable Isotope Pulse Method
Frailty is a common clinical syndrome in older adults that increases the risk for poor health outcomes including falls, disability, hospitalization, and mortality.
- Trial name
- NCT07254403
- Testing
- Beef, Tofu
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Primary Percutaneous Coronary Intervention
Prognostic Value of the CALLY Index in Patients Undergoing Primary PCI
This study aims to evaluate the relationship between the admission CALLY index and short-term adverse outcomes in STEMI patients undergoing PPCI.
- Trial name
- NCT07203573
- Volunteers
- 140 people
- Sponsor
- Assiut University
Pustular Psoriasis (PP)
International Rare And Severe Psoriasis Expert Network
This registry is a prospective observational study in order to describe primarily the natural course of PP subtypes and to gain detailed information about their phenotype.
- Trial name
- IRASPEN (NCT04359394)
- Testing
- biological sampling, Phenotypic description, Photography
- Where
- 8 sites in Germany, Italy and 4 more
- Volunteers
- 180 people
- Sponsor
- University Hospital, Basel, Switzerland
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.