Clinical trials: Protein Malnutrition
Orthopedic, Osteo Arthritis Knee
Energy Status and Protein Intake As Prognostic Indicators of Rehabilitative Outcomes
The proposed project is novel in its goal to establish a foundation for evidence-based rehabilitative nutrition guidelines to enhance perioperative patient care and improve post-operative rehabilitative outcomes specific to…
- Conditions
- Orthopedic, Osteo Arthritis Knee, Hip Osteoarthritis, Protein-Energy Malnutrition
- Trial name
- ESPI-PRO (NCT06734845)
- Testing
- Total Knee Arthroplasty, Total Joint Arthroplasty
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
End-Stage Renal Disease, Malnutrition
A Plant Based High Protein Diet to Improve Nutritional Outcomes in Peritoneal Dialysis Patients
The study proposes that addition of high protein plant based diet will improve serum albumin as well serum phosphate for patients with End Stage Renal Disease (ESRD) on Dialysis.
- Trial name
- PBPD (NCT02360748)
- Testing
- Plant based high protein food items
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Ochsner Health System
Appetite Loss, Physical Inactivity
APPETITE: Plant Protein and Exercise Solutions for the Prevention of Undernutrition in Older Adults.
The APPETITE Trial aims to investigate the efficacy of innovative plant protein fibre (PPF) products (developed in a previous workpackage) as part of a personalised diet with/out physical activity on appetite and incidence of…
- Conditions
- Appetite Loss, Physical Inactivity, Undernutrition, Anorexia of Aging
- Trial name
- NCT05608707
- Testing
- Physical activity intervention, Personalised nutrition intervention
- Where
- 3 sites in Germany, Ireland and 1 more
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Malnutrition (Calorie), Protein-energy Malnutrition
Composite Flour Cookies for Improving Nutrition in Malnourished Children
Malnutrition is a major public health concern among children in developing countries, leading to impaired growth and increased risk of morbidity.
- Trial name
- CFC-MAL (NCT07504133)
- Testing
- Composite Flour Cookies
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Mairaj Noor
Malnutrition
Evaluation of a High Calorie, High Protein Tube Feeding Product in an Adult Population With or at Risk of Malnutrition
This prospective, observational study is designed to observe the use of a high calorie, high protein tube feed product in adults that are malnourished or at risk of malnutrition, as assessed by a clinician, and have been placed…
- Trial name
- NCT03459001
- Testing
- Tube Feeding Product
- Where
- 9 sites in Spain
- Volunteers
- 17 people
- Sponsor
- Abbott Nutrition
Dementia, Dementia, Mild
Chocolate and Physical Exercise to Reduce Malnutrition in Pre-dementia Aged People
We hypothesize that the antioxidant and cytoprotective functions of vitamin E combined with the cortisol-lowering effect of chocolate polyphenols and physical activity may help prevent the age-dependent decline of mitochondrial…
- Conditions
- Dementia, Dementia, Mild, Dementia Moderate, Dementia Senile
- Trial name
- Choko-AGE (NCT05343611)
- Testing
- Combination of High Protein Diet and Physical Exercise protocol, HPP Choko, HPP/VE Choko
- Where
- 4 sites in Italy
- Volunteers
- 102 people
- Sponsor
- Massimo Venturelli, PhD
Malnutrition
Adding Appetite Stimulants to an ONS in Older Adults
Study to determine whether adding specific nutrients to a high-protein oral nutritional support (ONS), with and without fibre can reduce the feeling of satiety and may increase appetite in adults older than 65 years.
- Trial name
- APPOLO II (NCT06645184)
- Testing
- Oral nutritional supplement
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Protein-Energy Malnutrition, Anorexia
Energy Dense Formula to People Living in Old Peoples Home
Dietary intake in frail elderly is often lower than estimated needs due to the combined effects of the anorexia of ageing, frailty and the presence of acute and chronic disease.
- Conditions
- Protein-Energy Malnutrition, Anorexia, Weight Change
- Trial name
- NCT01259999
- Testing
- Calogen extra strawberry
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska University Hospital
Mobility Limitations, Malnutrition
Older Person's Exercise and Nutrition Study
The novelty with the OPEN study is to evaluate the effects of the simple sit-to-stand exercise during routine care, in combination with an oral protein-rich supplement, on functional status and independence in frail older…
- Trial name
- OPEN (NCT02702037)
- Testing
- oral protein-rich supplement, Exercise
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Malnutrition, Calorie, Malnutrition; Protein
The Impact of Artificial Intelligence Dietary Smartphone Application on Nutritional Status Among Cancer Patients
Multi-center prospective pilot trial study
- Conditions
- Malnutrition, Calorie, Malnutrition; Protein, Weight Change, Body
- Trial name
- NCT04643626
- Testing
- artificial intelligence dietary android mobile application
- Where
- Malaysia
- Volunteers
- 56 people
- Sponsor
- Universiti Putra Malaysia
Malnutrition
TOLER-ENT Study: A Study to Investigate the Tolerance of the High Energy, High Protein Formula Sondalis® HP 2 kcal
A multicentre, prospective, open-label, single arm study for 2 months, involving adult patients under poorly tolerated Home Enteral Nutrition (HEN).
- Trial name
- SONDALIS (NCT05429853)
- Testing
- Sondalis® HP 2 kcal (with or without fibre)
- Where
- 2 sites in France
- Volunteers
- 17 people
- Sponsor
- Société des Produits Nestlé (SPN)
Prolonged Mechanical Ventilation, Protein Deficiency
High Protein, Core Muscle Rehab, Muscular Electrostimulation in Prolonged Mechanical Ventilation
The goal of this clinical trial is to learn about in patients with prolong mechanical ventilation. This main questions aims to answer are: High protein formula intake benefit in successful weaning from ventilator Core muscle…
- Trial name
- NCT05932134
- Testing
- UC + high protein diet (HP), UC + HP + core muscle rehabilitation, UC + HP + core muscle rehabilitation + neuromuscular electric stimulation (NMES)
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
AKI, CKD
Genetics in the Progression of Nephropathies
This study evaluates the role of genetic in the development and progression of different nephropaties with particular attention to: AKI CKD Hypertension ADPKD CKD-MBD Patients with decompensated heart failure undergoing either…
- Conditions
- AKI, CKD, Ckd-Mbd, CKD (Chronic Kidney Disease) Stage 5D
- Trial name
- NCT06416761
- Testing
- genetic polymorphisms
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- Ospedale San Raffaele
Undernutrition
Microbiota and Protein-energy Wasting (MIDIWA)
Oral supplementation with branched chain amino acids (BCAA) increases the levels of circulating BCAA, stimulates BCAA uptake in muscles, and decreases amino acid release from muscle, eventually promoting muscle anabolism.
- Trial name
- MIDIWA (NCT02962089)
- Testing
- Branched chain amino acids (BCAA)
- Where
- 5 sites in Switzerland
- Volunteers
- 37 people
- Sponsor
- University Hospital, Geneva
Peritoneal Dialysis Complication, Hypoalbuminemia
The Effect of Natural Protein vs. Protein Supplements on Peritoneal Dialysis Patients
This study is a prospective open label clinical trial comparing serum albumin levels and total protein intake in the peritoneal dialysis patient population.
- Conditions
- Peritoneal Dialysis Complication, Hypoalbuminemia, Malnutrition
- Trial name
- NCT03569410
- Testing
- increased protein intake via natural foods, increase protein intake via protein supplements
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Chronic Kidney Disease, Peritoneal Dialysis
Effect of Protein-Restricted Diet on Nitrogen Balance and Residual Renal Function in Peritoneal Dialysis (PD) Patients
Current therapy recommendations suggest a low protein diet to preserve residual renal function (RRF) before the start of dialysis, but a higher protein intake during dialysis to prevent protein-energy wasting (PEW).
- Trial name
- NCT00633646
- Testing
- diets contained different levels of protein
- Volunteers
- 94 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Nasopharyngeal Carcinoma, Malnutrition
The Function of PA, RBP and TRSF in Malnutrition Detecting and Nutritional Status Monitoring for NPC Patients
The purpose of this study is to study the function of pre-albumin, retinol conjugated protein and transferrin in early malnutrition detecting and nutritional status dynamic monitoring for local advanced nasopharyngeal carcinoma…
- Trial name
- NCT03240835
- Testing
- cisplatin and docetaxel, IMRT
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhao Chong
Malnutrition; Protein
True Ileal Amino Acid Digestibility of Tenebrio Molitor Larvae in Women
Dietary protein intake of adequate quality is essential for human health. Traditional animal source foods play a key role in providing high quality protein but are associated with a high burden on the environment.
- Trial name
- NCT05885191
- Testing
- 2H intrinsically-labeled T.molitor with 13-C labeled amino acid mixture
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Diego Moretti
Weight Loss, Starvation
Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity
The purpose of this study is to determine if an increased protein intake can attenuate the suppression of metabolic and anabolic hormones during caloric restriction
- Trial name
- NCT02945410
- Testing
- Caloric Restriction, Protein, Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Kwashiorkor, Marasmus
Safety and Metabolic Study of Highly Active Antiretroviral Therapy (HAART) in Malnourished Children With HIV
It is unclear whether children with HIV and severe acute malnutrition can be started on highly active antiretroviral therapy (HAART) safely while they are still malnourished and the manner in which this therapy should start.
- Conditions
- Kwashiorkor, Marasmus, Severe Acute Malnutrition, HIV
- Trial name
- ARMAM (NCT01529125)
- Testing
- zidovudine, lamivudine, nevirapine
- Where
- Malawi
- Volunteers
- 42 people
- Sponsor
- Washington University School of Medicine