Clinical trials: Protein Malnutrition
Malnutrition; Protein, Protein Malnutrition
Increase Protein Intake of Older Meal Service Clients With Readymade Protein-rich Meals and Foods
Rationale: Undernutrition risk among community-dwelling older adults in developed countries is shown to be around 24%. Increasing protein intake is a strategy that is feasible as well as efficacious to reduce undernutrition in…
- Trial name
- ConsuMEER (NCT03032237)
- Testing
- Nutritional intervention - protein-rich, Nutritional intervention - standard
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- HAN University of Applied Sciences
Hypophosphatasia (HPP)
Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)
This clinical trial studies the safety, tolerability, and pharmacology of asfotase alfa when given to adults with HPP.
- Trial name
- NCT00739505
- Testing
- Asfotase Alfa
- Where
- 3 sites in United States, Canada
- Volunteers
- 6 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Sarcopenia, Muscle Loss
Impact of Protein-Enriched Lacto-Vegetarian Soup on Muscle Mass and Muscle Strength Among Older Adults
The study is a 12-week randomized controlled trial designed to evaluate the clinical effects of protein-enriched Lacto-vegetarian soups on body composition, muscle strength, and physical performance among community-dwelling older…
- Conditions
- Sarcopenia, Muscle Loss, Malnutrition
- Trial name
- NCT05243472
- Testing
- Protein nutritional supplement
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Critical Illness, Malnutrition
Comparative Effect of Protein Prescription Strategies on Nitrogen Balance and Upshots in Critically Ill Patients
This is Interventional clinical trail will be conducted in Internationale hospital ICU s patients with higher nutrition risk. two doses of protein 1 g/kg/day Vs 2 g/ kg day will be given and its outcome will be checked on…
- Conditions
- Critical Illness, Malnutrition, Protein
- Trial name
- NCT04468503
- Testing
- Two differnt protien prescription (ig per kg per day and 2g per kg /day )will be assigned to each group interventional
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Allama Iqbal Open University Islamabad
Vitamin B12 Deficiency
Holotranscobalamin Remains Unchanged During Pregnancy
Background and objective: Plasma cobalamins decrease during pregnancy but it is not fully elucidated how this is reflected in the total and cobalamin saturated transport proteins, transcobalamin (total TC, holoTC) and haptocorrin…
- Trial name
- NCT00467623
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Environmental Enteric Dysfunction (EED), Malnutrition
The Maternal EED Study
Undernutrition among women of reproductive age is more common in South Asia than in any other region. In South Asia, the prevalence of maternal undernutrition varies between 10 and 40%.
- Conditions
- Environmental Enteric Dysfunction (EED), Malnutrition, Women of Reproductive Age, Gut Microbiota
- Trial name
- NCT05862363
- Testing
- Microbiota-directed balanced energy protein (MD-BEP), Ready-to-use supplementary food-balanced energy protein (RUSF-BEP), Esophagogastroduodenoscopy (EGD)
- Where
- Bangladesh
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Metabolic and Nutritional Complications, Protein Malnutrition
Laparoscopic Revision From Biliopancreatic Diversion to Gastric Bypass
The aim of this study is to describe the clinical presentation, indications, and operative treatment as well as assess the morbidity, mortality, and overall performance of revisional GBP after either failed and/or complicated…
- Conditions
- Metabolic and Nutritional Complications, Protein Malnutrition, Intestinal Malabsorptive Syndrome, Metabolic Bone Disease
- Trial name
- BPD-to-RYGB (NCT01041456)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Sarcopenic Obesity, Bariatric Surgery Candidate
Effect of Protein Supplementation and a Structured Exercise Program on Muscle in Women After Bariatric Surgery.
Obesity is considered a chronic disease that increases the risk of developing diseases that reduce life expectancy. The treatment of obesity is complex.
- Conditions
- Sarcopenic Obesity, Bariatric Surgery Candidate, Nutritional Deficiency, Protein Intolerance
- Trial name
- SarcoFit (NCT04771377)
- Testing
- Protein Supplementation
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Hospital Clinic of Barcelona
End Stage Renal Disease
Effects of Nutritional Supplementation on Protein and Energy Homeostasis in Malnourished Chronic Hemodialysis Patients
The goal of this study is to evaluate the metabolic effects of concomitant use of three consecutive doses of recombinant human growth hormone over three days and exercise during continuous nutrient infusion in chronic…
- Trial name
- NCT00244075
- Testing
- nutritional supplement, recombinant human growth hormone (rcGH), exercise
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Vanderbilt University
Oxidative Stress, Protein-Energy Wasting
Effect of Oral Nutritional Supplementation on Oxidative Stress in Protein-energy Wasting Patients With Peritoneal Dialysis
End-stage kidney disease (ESKD) represents a serious public health problem in Mexico. Data from the United States Renal Data System (USRDS) have reported that the region of Jalisco (Mexico) is one of the places with the highest…
- Conditions
- Oxidative Stress, Protein-Energy Wasting, Malnutrition, Protein-Energy Malnutrition
- Trial name
- NCT04628117
- Testing
- Oral nutritional supplementation for kidney disease
- Volunteers
- 22 people
- Sponsor
- Hospital Civil Juan I. Menchaca
Pregnancy, Protein-Energy Malnutrition
NutFish and Nutrient Supplementation in Pregnancy Class to Improve Maternal and Birth Outcomes
This study evaluates the intervention of Nut Fish based food, micro nutrients supplementation and pregnancy class to improve maternal and birth outcome. This is cluster randomized trial with two arms.
- Conditions
- Pregnancy, Protein-Energy Malnutrition, Anemia
- Trial name
- NCT02959125
- Testing
- NutFish Based Food Supplementation, Multiple micronutrients, Health Education in Pregnancy Class
- Where
- 2 sites in Indonesia
- Volunteers
- 72 people
- Sponsor
- Semarang Health Polytechnic
Vitamin d Deficiency
Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Major Surgical Procedures.
Vitamin D (Vitamin D) deficiency is very common. We recently showed that 97% of 204 patients admitted to Truman Medical Center were Vitamin D deficient (<30 ng/ml).
- Trial name
- NCT02138591
- Testing
- Blood draw pre-operatively, Blood draw post-operative Day 1, Blood draw post-operative Day 2
- Where
- United States
- Sponsor
- University of Missouri, Kansas City
Nutrition Disorders, Life-threatening Infection
Cotrimoxazole Prophylaxis in Severely Malnourished Children
This trial aims to test the hypothesis that mortality among Kenyan children with severe malnutrition following initial stabilisation is due to ongoing vulnerability to infectious disease, and that long term daily co-trimoxazole…
- Trial name
- CTX (NCT00934492)
- Testing
- Cotrimoxazole dispersible tablet
- Where
- 4 sites in Kenya
- Volunteers
- 1,781 people
- Sponsor
- University of Oxford
Protein-Energy Malnutrition, Physical Disability
The (Cost)Effectiveness of Increasing Protein Intake on Physical Funtioning in Older Adults
In this RCT with the duration of 6 months among 264 community-dwelling older adults (65+ years) with habitual low protein intake, the investigators will examine the long term (cost) effectiveness of increasing daily protein…
- Trial name
- NCT03712306
- Testing
- Dietary advice, Dietary advice and advice on timing
- Where
- 2 sites in Finland, Netherlands
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Hypophosphatasia (HPP)
Extension Study of Protocol ENB-006-09 - Study of Asfotase Alfa in Children With Hypophosphatasia (HPP)
This clinical trial studies the long term safety and efficacy of asfotase alfa in children with HPP who completed Study ENB-006-09 (NCT00952484).
- Trial name
- NCT01203826
- Testing
- Asfotase Alfa
- Where
- 2 sites in United States, Canada
- Volunteers
- 12 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Respiratory Infections, Diarrhea
High/Low Dose Vit A in Diarrhea/ALRI in Severe PEM
Vitamin A deficiency is an important health problem globally including Bangladesh. The problem is greater among under-five children, particularly in malnourished.
- Conditions
- Respiratory Infections, Diarrhea, Malnutrition
- Trial name
- NCT00388921
- Testing
- Vitamin A
- Where
- Bangladesh
- Volunteers
- 260 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Malnutrition
An Observational Study of a Nutritional Supplement in an Older Malnourished or at Risk of Malnutrition, Hip Fracture Population
This non-interventional, prospective, observational study is designed to observe the use of high calorie, high protein oral nutritional supplement in malnourished or at risk of malnutrition patients after hip fracture surgery, as…
- Trial name
- NCT03882944
- Where
- 17 sites in Spain
- Volunteers
- 310 people
- Sponsor
- Abbott Nutrition
Growth Failure, Stunting
ELICIT 2.0: Pilot Study of the Effect of Maternal Protein Supplementation During Lactation on Childhood Growth
Haydom Global Health Research Center in north central Tanzania represents an important rural setting for performing high-quality medical research in sub-Saharan Africa.
- Conditions
- Growth Failure, Stunting, Malnutrition, Protein Malnutrition
- Trial name
- NCT04565314
- Testing
- Plumpy'Mum
- Where
- Tanzania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Protein-Calorie Malnutrition
Dialysis Model for Outcome and Nutrition Decision
This study is the secondary phase of Taiwan Prediction Model Project Plan (TPMPP). The investigators try to design a prospective randomized control trial with nutrition intervention to validate 3 prediction models the…
- Trial name
- DIAMOND (NCT03642678)
- Testing
- ONS
- Where
- Taiwan
- Volunteers
- 422 people
- Sponsor
- An Hsin QingShui Clinic
Vitamin d Deficiency, Vitamin B 12 Deficiency
ETOL-Elderly Study of the Efficiency of the Innovative Food Supplement in Elderly Adults
The aim of this pilot study is to conduct a study on geriatric population in Slovenia (non-users of dietary supplements/medicines with vitamine D, vitamin B12 and protein) and assess deficiency of selected nutrients, and to…
- Conditions
- Vitamin d Deficiency, Vitamin B 12 Deficiency, Protein Deficiency
- Trial name
- ETOL-Elderly (NCT05661006)
- Testing
- Use of food supplement
- Where
- Slovenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)