Clinical trials: Proximal Femoral Fracture, open to volunteers
Proximal Humeral Fractures
Hip-allograft In Proximal Humerus Fractures Versus Plate Implantation Alone: a Randomized Controlled Trial
Proximal humerus fractures (PHFs) are common osteoporotic fractures in adults and the elderly, leading to significant disability and reduced quality of life.
- Trial name
- HIPPI (NCT07538700)
- Testing
- Locking plate fixation with femoral allograft augmentation
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Tergooi Medical Center
Pertrochanteric Fracture
Static Helical Screw Locking of Pertrochanteric Femur Fractures Using the TFN-A
The study will investigate the shortening and collapse of pertrochanteric fractures following surgical management with the TFN-Advanced nailing system.
- Trial name
- TFN-A (NCT04851509)
- Testing
- Dynamic Rotational Locking, Static Locking
- Where
- Canada
- Volunteers
- 218 people
- Sponsor
- Fraser Orthopaedic Research Society
Proximal Femur Fracture, Hip Fracture
Ultrasound-Guided PENG Block vs Femoral Nerve Block for Analgesia Before Spinal Anesthesia in Hip Fracture Surgery
This study will compare two types of ultrasound-guided nerve blocks-Pericapsular Nerve Group (PENG) block and Femoral Nerve Block (FNB)-to evaluate their effectiveness in reducing pain before spinal anesthesia in patients who…
- Conditions
- Proximal Femur Fracture, Hip Fracture, Pain Management, Spinal Anesthesia
- Trial name
- NCT06989047
- Testing
- Pericapsular Nerve Group (PENG) Block, Femoral Nerve Block (FNB)
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Cognitive Decline, Delirium
CITADEL: Effectiveness of CITicoline in Preventing Cognitive Decline After DELirium
The aim of this study is to assess whether citicoline (TRAUSAN), a neuroprotective agent involved in membrane phospholipid synthesis and neurotransmission, can prevent or attenuate cognitive decline in older adults who develop…
- Trial name
- CITADEL (NCT07804498)
- Testing
- Citicoline
- Where
- Italy
- Volunteers
- 122 people
- Sponsor
- University of Milano Bicocca
Osteoporosis
RECONFIRM - Study of AGN1 LOEP in Patients with Osteoporosis
The research will be conducted as a prospective, post-market, multi-center study within Europe. The maximum number of subjects to be treated is 150 across up to 20 sites. This will be a non-randomized and open-label study.
- Trial name
- NCT05202678
- Testing
- AGN1 LOEP
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- AgNovos Healthcare, LLC
Orthopedic Disorder, Trauma Injury
X-BS Ortho Bone Graft Study
Randomised investigation of the osteoconductive performance and safety of CE-marked FDBS bone graft (GraftR3®), with contextual reference to CE-marked IBS (MBCP® Putty), in the filling of orthopaedic bone defects.
- Conditions
- Orthopedic Disorder, Trauma Injury, Extremity Injury
- Trial name
- NCT06326827
- Testing
- FDBS (GraftR3®), IBS (MBCP® Putty)
- Volunteers
- 200 people
- Sponsor
- Advanced Medical Solutions Ltd.
Hip Fractures
Pericapsular Nerve Group Block Versus Femoral Nerve Block Study
Hip fractures are common in older adults and are often associated with severe pain, making it difficult for patients to sit for spinal anesthesia before surgery.
- Trial name
- NCT07717463
- Testing
- Ultrasound-Guided Pericapsular Nerve Group (PENG) Block, Ultrasound-Guided Femoral Nerve Block, Spinal Anesthesia (bupivacaine)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Femoral Fracture
A Study to Verify if the Surgery for the Proximal Femur Fracture Can be Improved With the Help of a Navigation System
The ADAPT system is a software that calculate a virtual 3D reconstruction of the femoral head without additional radiation. It automatically detects the used implant and its position relative to the femoral head, helping the…
- Trial name
- NCT04494672
- Testing
- Intramedullary nailing with ADAPT system, Intramedullary nailing without ADAPT system
- Where
- Switzerland
- Volunteers
- 96 people
- Sponsor
- Christian Candrian
Bone Metastases, Pathological Fracture
Short Versus Long Intramedullary Nails in the Treatment of Proximal Femur Metastasis.
The goal of this interventional randomized controlled trial is to compare the clinical outcomes in treating extremities pathological fractures (fractures of limbs caused by metastatic tumors) or impending pathological fractures…
- Conditions
- Bone Metastases, Pathological Fracture, Pathological Fracture, Left Femur, Pathological Fracture, Right Femur
- Trial name
- NCT05969470
- Testing
- Internal fixation with short intramedullary nails, Internal fixation with long intramedullary nails
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Hip Fracture, Proximal Femur Fracture
Frailty and Nottingham Hip Fracture Score for Predicting 90-Day Mortality After Hip Fracture Surgery
Hip fractures are serious injuries that occur mostly in older adults. Many people experience health problems or may die in the months after surgery.
- Conditions
- Hip Fracture, Proximal Femur Fracture, Frailty
- Trial name
- NCT07481188
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Trakya University
Anesthesia, Spinal, Hip Fractures
Haemodynamic Effects and Complications of Continuous Versus Single-shot Spinal Anaesthesia for HIP Fracture Surgery
This research project aims to identify a safer method of spinal anaesthesia for elderly patients undergoing surgical stabilisation of proximal femoral fractures.
- Trial name
- CHIPS (NCT07358299)
- Testing
- Bupivacaine Spinal 0,5% Heavy - bolus, Bupivacaine Spinal 0,5% Heavy - titration
- Where
- 2 sites in Poland
- Volunteers
- 216 people
- Sponsor
- Centre of Postgraduate Medical Education
Femoral Fractures
Combined Nail and Plate Fixation in Proximal Femoral Fractures With Lateral Wall Deficiency
Proximal femoral fractures are a major cause of hospitalization and disability worldwide (1). They are commonly seen among elderly patients after low-energy trauma and in younger adults after high-energy injuries and represent a…
- Trial name
- NCT07277569
- Testing
- Proximal femoral nail with lateral plate augmentation
- Volunteers
- 17 people
- Sponsor
- Assiut University
Osteoporosis
GRACE II (General Retrospective Analysis of Commercial Experience With AGN1 LOEP)
The study is designed as a retrospective, multicenter study for subjects previously treated with the AGN1 LOEP Kit in the proximal femur as part of standard hospital practice. This will be a non-randomized and non-blinded study.
- Trial name
- NCT07594639
- Testing
- AGN1 LOEP
- Where
- Belgium
- Volunteers
- 305 people
- Sponsor
- AgNovos Healthcare, LLC
Learning Curves and Outcomes of Simulation-based Training
Is Two-on-one Instruction in Virtual Reality Simulation-based Training of Operating Fractures of the Hip for Medical Students as Effective as One-on-one Instruction
The training of orthopedic surgeons has historically relied heavily on an apprenticeship model as the primary way of teaching the various procedures an aspiring surgeon needs to master.
- Trial name
- NCT06612619
- Testing
- Dyad instruction
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation