Clinical trials: Prurigo Nodularis
Prurigo Nodularis, Atopic Dermatitis
Transcriptomic Landscape of T Lymphocytes of Atopic Dermatitis, Atopic Prurigo Nodularis (of Besnier) and Non-atopic Prurigo Nodularis (of Hyde) Using Single Cell RNA-sequencing
Prurigo nodularis (PN) is a skin condition characterized by symmetrically distributed widespread, pruritic nodules that occurs in patients with chronic pruritus.
- Trial name
- PRURISEQ (NCT04681300)
- Testing
- Skin biopsy, Plastic surgery remnants
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prurigo Nodularis
Safety and Efficacy of Nemolizumab in PN
The aim of this study is to assess the safety and efficacy of nemolizumab in subjects with prurigo nodularis.
- Trial name
- NCT03181503
- Testing
- CD14152 Dose A
- Where
- 16 sites in Austria, France and 2 more
- Volunteers
- 70 people
- Sponsor
- Galderma R&D
Prurigo Nodularis
Apremilast as Anti-pruritic Treatment in Patients With Prurigo Nodularis
This study will evaluate the anti-pruritic effect of apremilast in patients with known PN.
- Trial name
- NCT03576287
- Testing
- Apremilast Oral Product
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Tanja Todberg, MD
Prurigo Nodularis
Safety and Efficacy of CC-10004 for Prurigo Nodularis
This trial will include: Study period up to 7 months. Office visits monthly lasting approximately 1 hour. Blood Draws. Oral medication that is taken 2 times daily. Photographs and biopsies if agreed.
- Trial name
- NCT00869089
- Testing
- CC-10004
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University Hospitals Cleveland Medical Center
Prurigo Nodularis
Evaluation of the Antipruritic Effect of Elidel (Pimecrolimus) in Non-atopic Pruritic Disease
The development of the topical calcineurin inhibitor pimecrolimus resulted in a significant improvement in the treatment of atopic dermatitis. In addition, an excellent amelioration of pruritus could be regularly observed.
- Trial name
- CASM981CDE21 (NCT00507832)
- Testing
- Pimecrolimus, Hydrocortisone
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Muenster
Prurigo Nodularis
Effectiveness of the Selective Serotonin Reuptake Inhibitor,Citalopram (Cipralex), in Prurigo Nodularis
Prurigo nodularis (PN) is a common dermatological disorder, manifested as scaly nodules which appear mainly on the extensor surfaces of the limbs.
- Trial name
- NCT00532519
- Testing
- citalopram (cipralex)
- Where
- Israel
- Sponsor
- Hadassah Medical Organization