Clinical trials: Pruritis
Pruritis
Comparative Study of the Efficacy of SARNA Sensitive Lotion for Treatment of Uremic Itch in Adult Hemodialysis Patients
The purpose of this research study is to evaluate the efficacy of SARNA Sensitive Lotion in the treatment of uremic pruritus in adult hemodialysis patients in a double-blind Controlled comparative trial.
- Trial name
- NCT00693654
- Testing
- Sarna, Cetaphil
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Wake Forest University
Pediatric Cholestasis
A4250, an IBAT Inhibitor in Pediatric Cholestasis
This study will evaluate A4250 (IBATinhibitor) as a treatment option in pediatric patients with chronic cholestasis with main emphasis on safety evaluation and on effects on pruritus
- Trial name
- NCT02630875
- Testing
- A4250
- Where
- 7 sites in Denmark, France and 3 more
- Volunteers
- 24 people
- Sponsor
- Albireo
Pemphigoid, Pruritus
Pruritus and Pemphigoid in Nursing Home Patients
The primary objective of this observational study is to describe the prevalence of pruritus and pemphigoid in nursing home patients.
- Trial name
- SSENIOR (NCT02823067)
- Testing
- Blood sample
- Where
- Netherlands
- Volunteers
- 125 people
- Sponsor
- M.F. Jonkman
Urticaria
Safety and Efficacy of Abatacept in Subjects With Chronic Urticaria Who Have Had an Inadequate Response to Anti-histamine Therapy
This study is being done to find out if a drug called Abatacept (Orencia ®) is safe and effective in treating people with chronic urticaria (persistent hives).
- Trial name
- TAHOE (NCT00886795)
- Testing
- abatacept (Orencia ®)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University
Pruritus
Gabapentin for Prophylaxis Intrathecal Morphine-Induced Pruritus
Intrathecal morphine provides good postoperative analgesia for up to 18-24 hour after administration. Pruritus is the most common side effect of intrathecal morphine, which the incidence was reported as 20%-100%2 and 63% in…
- Trial name
- NCT01236859
- Testing
- Gabapentin
- Where
- Thailand
- Volunteers
- 180 people
- Sponsor
- Prince of Songkla University
Tinea Pedis
A Dose Response Trial to Evaluate Clinical and Mycological Effect of Nitric Oxide in Subjects With Tinea Pedis
A multi-arm trial to evaluate the efficacy and safety of using gaseous nitric oxide to treat moderate to severe tinea pedis.
- Trial name
- NCT00893880
- Testing
- 1% gaseous Nitric Oxide blended in Oxygen
- Where
- 4 sites in Canada, Saint Kitts and Nevis
- Volunteers
- 92 people
- Sponsor
- Nitric BioTherapeutics, Inc
Chronic Pruritus
Study of Kids Itch Severity (SKIS)
This purpose of this study is to validate two measures of chronic itching in kids: itch severity (ItchyQuant) and the impact on their quality of life (ItchyQoL).
- Trial name
- SKIS (NCT02672579)
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- Emory University
Pruritus
Efficacy of CeraVe® Moisturizing Cream on Skin Pruritus in Elderly Patients
The goal of this clinical trial is to evaluate the CeraVe® moisturizing cream's efficiency on the improvement of skin barrier in patients with chronic elderly pruritus.
- Trial name
- NCT05779150
- Testing
- CeraVe® Moisturising Cream, Standard Cream
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Zhongshan Hospital
Psoriasis, Healthy
Brain Changes in Psoriasis After Secukinumab Treatment
The purpose of this study is to assess the effect of a biologic drug targeting the Interleukin (IL)-17 pathway (secukinumab) on brain plasticity and examine whether the plastic changes correlate with the improvement of perception…
- Trial name
- NCT04717466
- Testing
- Secukinumab
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Miami
Morphine, Morphine Adverse Reaction
Side Effects of a Single Shot Intrathecal Morphine in Clinical Practice, a Retrospective Analysis
ITM has the potential to be a powerful tool for multimodal postoperative pain management, understanding, preventing and managing its side effects is crucial for upturn of patient safety and comfort.
- Conditions
- Morphine, Morphine Adverse Reaction, Morphine Induced Pruritis, Nausea and Vomiting, Postoperative
- Trial name
- NCT07238179
- Testing
- Intrathecal Morphine
- Where
- Belgium
- Volunteers
- 600 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pruritus, Atopic Dermatitis
Blinded, Randomized Study Evaluating Aurstat Versus Control in the Treatment of Atopic Dermatitis Associated Pruritus
To demonstrate the ability of Aurstat to reduce pruritus in subjects with mild to moderate atopic dermatitis. Efficacy results will be based on subject assessment, IGA, and photographic evidence based on ordinal scales for…
- Trial name
- AUR0613 (NCT01905631)
- Testing
- Aurstat Anti-Itch Hydrogel (Aurstat)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Center for Clinical and Cosmetic Research
Intrahepatic Cholestasis of Pregnancy
A Placebo-controlled Study of Volixibat in Subjects With Elevated Serum Bile Acids Associated With Intrahepatic Cholestasis of Pregnancy (OHANA)
Part 1 is an open-label randomized study of volixibat in patients with Intrahepatic Cholestasis of Pregnancy (ICP) and elevated serum bile acid concentrations (sBA) to evaluate safety and tolerability of two doses of volixibat.
- Trial name
- OHANA (NCT04718961)
- Testing
- Volixibat
- Where
- 20 sites in United States, New Zealand and 1 more
- Volunteers
- 4 people
- Sponsor
- Mirum Pharmaceuticals, Inc.
Tinea Pedis
Efficacy and Safety of Terbinafine Film Forming Solution in Patients With Tinea Pedis
This study will compare the efficacy and safety of a single dose of terbinafine film forming solution 1% with a single dose of placebo film forming solution in the treatment of tinea pedis.
- Trial name
- NCT01433107
- Testing
- Terbinafine
- Where
- 6 sites in China
- Volunteers
- 290 people
- Sponsor
- Novartis
Itching, Xerosis
The Role of Skin Care Regimen in Skin Health
This research is being done to evaluate the role of a regular skin care regimen comprising of a mild soap and moisturizer in improving dry skin and overall skin health.
- Trial name
- NCT03497130
- Testing
- skin care regimen
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Johns Hopkins University
Vaginal Odor
The Effects of an Orally-Administered Probiotic on Vaginal Symptoms
This randomized, double-blind, placebo-controlled, virtual trial is designed to determine the efficacy of an orally-administered probiotic on alleviating vaginal odor and other vaginal symptoms.
- Trial name
- NCT07829861
- Testing
- Orally-administered probiotic
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Bonafide Health
Atopic Dermatitis (AD)
Study of Ruxolitinib Cream in Adolescents With Atopic Dermatitis
The purpose of this study is to evaluate the long-term safety and tolerability of ruxolitinib cream in adolescents with Atopic Dermatitis (AD).
- Trial name
- NCT05456529
- Testing
- Ruxolitinib Cream
- Where
- 38 sites in United States, Canada and 1 more
- Volunteers
- 103 people
- Sponsor
- Incyte Corporation
Pruritus
Acupuncture for Prevention of Itch in Caesarean Section
This study aims to determine the effectiveness of using a commercially available acupuncture stud at the LI11 acupuncture point at reducing the severity of itch caused by intrathecal diamorphine in elective caesarean section.
- Trial name
- NCT03458572
- Testing
- Seirin Pyonex press needle acupuncture
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Psoriasis, Cutaneous T Cell Lymphoma
Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases
The molecular mechanisms of action of photo(chemo)therapy in skin diseases are investigated in this study. The phototherapeutic modalities employed include UVB (ultraviolet B), UVA (ultraviolet A), PUVA (psoralen+UVA) and/or…
- Conditions
- Psoriasis, Cutaneous T Cell Lymphoma, Lymphoproliferative Disorders, Eczema
- Trial name
- BioUV2017 (NCT03340155)
- Testing
- Photo(chemo)therapy
- Where
- Austria
- Volunteers
- 240 people
- Sponsor
- Medical University of Graz
Tinea Pedis
Evaluate the Safety and Efficacy of Naftifine Hydrochloride Cream 2% and Naftin® Cream 2% in Patients With Tinea Pedis
The objective of this study is to compare the efficacy and safety of the test formulation of Naftifine Hydrochloride Cream 2% to Naftin® (Naftifine Hydrochloride) 2% Cream in a 6 week study in patients with tinea pedis.
- Trial name
- NCT02132260
- Testing
- Naftifine Hydrochloride Cream 2%, Naftin® (Naftifine Hydrochloride) Cream 2%
- Volunteers
- 890 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Psoriasis, Pruritus
Methotrexate Versus Apremilast for Pruritus in Psoriasis
This randomized controlled trial aims to compare the efficacy of Methotrexate versus Apremilast in reducing pruritus and improving quality of life in patients with psoriasis.
- Trial name
- NCT07432386
- Testing
- Apremilast, Methotrexate
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Zarmeen Khawar