Clinical trials: Pseudoexfoliation Syndrome
Pseudoexfoliation Syndrome
The Correlation Between Pupil Size and Retinal Nerve Fibers Changes in Pseudoexfoliation Syndrome.
To study the possible correlation between pupillary diameter before and after dilation with intraocular pressure, lens stability and glaucomatous damage (represented by optic disc changes using cup to disc ratio and OCT changes…
- Trial name
- NCT06588816
- Testing
- optical coherence tomography
- Volunteers
- 33 people
- Sponsor
- Assiut University
Glaucoma, Open Angle Glaucoma (OAG)
Long-term Safety and Efficacy of a Modified Suprachoroidal Silicone Tube (SST) Shunt
The goal of this observational study is to evaluate the long-term safety and efficacy of a modified suprachoroidal silicone tube (SST) shunt in treating patients with primary open-angle glaucoma (POAG) and pseudo-exfoliative…
- Conditions
- Glaucoma, Open Angle Glaucoma (OAG), POAG, Ocular Hypertension
- Trial name
- NCT06691555
- Testing
- Suprachoroidal silicone tube (SST) shunt
- Where
- Georgia
- Volunteers
- 66 people
- Sponsor
- Davinci LTD
Primary Open Angle Glaucoma, Secondary Open Angle Glaucoma Due to PEX
Contrast Sensitivity in Glaucoma
The primary aim of the Erlangen´s Glaucoma Contrast Sensitivity-Study (EGCS-Study) is the evaluation of the diagnostic and prognostic validity of a diagnostic procedure, measuring contrast sensitivity.
- Trial name
- NCT00947869
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg
Exfoliation Syndrome, Glaucoma
The International Collaborative Exfoliation Syndrome Treatment Study
Purpose: To determine the efficacy of treatment with latanoprost in combination with pilocarpine versus timolol or timolol/dorzolamide fixed combination (Timoptic or Cosopt) in eyes with XFS and elevated intraocular pressure…
- Conditions
- Exfoliation Syndrome, Glaucoma, Ocular Hypertension
- Trial name
- NCT00804115
- Testing
- Latanoprost with Pilocarpine vs Timolol or Cosopt
- Where
- United States
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- The New York Eye & Ear Infirmary
Age Related Cataracts, Pseudoexfoliation Syndrome
Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome
The aim of this study is to compare the surgical outcomes of the two IOL implantation methods for eyes with cataract and PEX in a single-center and with highly experienced surgeons.
- Trial name
- NCT06053554
- Testing
- Phakoemulsification, Ziemer Z8 Femtolaser, Kowa Avansee Preset
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Exfoliation Syndrome, Ocular Hypertension
Randomized Prospective Study of Selective Laser Trabeculoplasty (SLT) Versus Argon Trabeculoplasty (ALT) in Patients With Pseudoexfoliation Glaucoma and Ocular Hypertension
Multi-center, prospective, randomized, controlled clinical trial to compare selective laser trabeculoplasty (SLT) and Argon laser trabeculoplasty (ALT) in pseudoexfoliation glaucoma and ocular hypertension patients.
- Trial name
- SLT (NCT01126203)
- Testing
- SLT, ALT
- Where
- 5 sites in Canada
- Volunteers
- 25 people
- Sponsor
- University of Calgary
Pseudoexfoliation Syndrome
The Possible Association Between Pseudoexfoliation Syndrome And Corneal Endothelial Cell Changes
The study aims to compare the endothelial cell count in patients with pseudoexfoliation syndrome to the the endothelial cell count in normal patients above the age of 50.
- Trial name
- NCT05156138
- Testing
- no interventions as it is a case control observational study
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Abdominal Aortic Aneurysms, Pseudoexfoliation Syndrome
Abdominal Aortic Aneurysms and Pseudoexfoliation Syndrome
Conflicting results have been reported concerning the association of pseudoexfoliation syndrome (PXF) and abdominal aortic aneurysms (AAA). Schumacher et al.
- Conditions
- Abdominal Aortic Aneurysms, Pseudoexfoliation Syndrome, Hypertension
- Trial name
- NCT00546013
- Where
- France
- Volunteers
- 208 people
- Sponsor
- European Georges Pompidou Hospital
Exfoliation Syndrome
Early Diagnosis in Glaucoma With GDxVcc
To compare the Retina Nerve Fiber Layer thickness, measured with Scanning Laser Polarimetry in subjects with exfoliation syndrome and normal controls and to evaluate the value of scanning laser polarimetry in the early diagnosis…
- Trial name
- NCT01022281
- Where
- Greece
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Glaucoma Eye, Open-angle Glaucoma
Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical Options
Glaucoma surgery currently relies on a wide therapeutic arsenal, ranging from conventional filtering surgeries to minimally invasive glaucoma surgery (MIGS).
- Conditions
- Glaucoma Eye, Open-angle Glaucoma, Closed-Angle Glaucoma, Pseudo Exfoliative Syndrome
- Trial name
- G-SCOPE (NCT07303257)
- Testing
- NEI-VFQ-25 (National Eye Institute Visual Function Questionnaire-25).
- Where
- France
- Volunteers
- 132 people
- Sponsor
- Hospices Civils de Lyon
Endothelial Cell Loss, Corneal
Endothelial Changes in Pseudoexfoliation Syndrome
this study aimed to evaluate the corneal endothelial cell changes before and after phacoemulsification in pseudoexfoliative patients relative to healthy adults.
- Trial name
- PEX (NCT05194891)
- Testing
- Specular Microscopy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cataract, Diabetes
Aqueous Flare of a Hydrophobic Acrylic Single-piece Open-loop IOL With Modified Material Surface Properties
Modern phacoemulsification techniques have made cataract surgery safe and efficient over the past several decades. Although the phacoemulsification procedure has improved greatly, cataract surgery still involves trauma.
- Conditions
- Cataract, Diabetes, Pseudoexfoliation Syndrome
- Trial name
- POL (NCT01767012)
- Testing
- Polylens EC-HY10-PAL (coated), Polylens EC-Y10-PAL (uncoated)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Glaucoma
Anterior Segment Imaging With Ultrahigh-resolution OCT in Patients With Glaucoma and PEX - a Pilot Study
The aim of the present study is to develop a measurement protocol for optimal imaging of the anterior segment of the eye, including anterior chamber angle, Schlemm's canal, filtering bleb and pseudoexfoliation deposits on the…
- Trial name
- NCT02865473
- Testing
- Pilocarpine
- Where
- Austria
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pupil Constriction, Iris Floppiness
Clinical Factors Associated Floppy Iris
This study is planned to investigate the incidence of intraoperative floppy iris and its relationship with pseudoexfoliation, diabetes, hypertension as well as systemic alpha-1 adrenergic blocker use.
- Conditions
- Pupil Constriction, Iris Floppiness, Iris Prolapsus From the Wound
- Trial name
- NCT00472888
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Baskent University
Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma
Patch Graft Material Safety and Effectiveness in Covering Glaucoma Drainage Device Tube
The investigators hypothesize that KeraSys is a safe as Tutoplast to cover the tube of the Molteno 3 glaucoma drainage device during surgery
- Conditions
- Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma, Pseudoexfoliation Glaucoma, Pigmentary Glaucoma
- Trial name
- NCT01301378
- Testing
- Molteno 3 glaucoma drainage shunt
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wills Eye
Cataract With Exfoliation Syndrome
Efficacy of a Capsular Tension Ring in Preventing Anterior Capsule Shrinkage After Cataract Surgery in Exfoliation Syndrome
The purpose of this study is to examine the efficacy of a capsular tension ring (CTR) in preventing anterior capsule shrinkage after cataract surgery in exfoliation syndrome (XFS) with no zonular weakness.
- Trial name
- Effect of CTR (NCT01455168)
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- University of Occupational and Environmental Health
Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma
Intraocular Pressure After Preserflo / Innfocus Microshunt Implantation vs Trabeculectomy
The aim of this project is to compare trabeculectomy with Preserflo / Innfocus Microshunt in patients with Primary Angle Open Glaucoma and Pseudoexfoliation Glaucoma regarding the reduction of intraocular pressure.
- Trial name
- PAINT (NCT04440527)
- Testing
- Preserflo / Innfocus Microshunt, Trabeculectomy
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Medical University Innsbruck
Exfoliation Syndrome, Primary Open Angle Glaucoma
Imaging Lens Deposits in Exfoliation Syndrome
The purpose of this study is to use a special eye imaging technique, anterior segment optical coherence tomography (AS-OCT), to image the lens (the curved, transparent part of the eye that helps you to see clearly by directing…
- Conditions
- Exfoliation Syndrome, Primary Open Angle Glaucoma, Cataracts
- Trial name
- NCT02042703
- Testing
- anterior segment OCT
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Duke University
Pseudoexfoliation Syndrome, Cataract
Influence of Cataract Surgery on Corneal Biomechanical Properties in Patients With Pseudoexfoliation Syndrome
Pseudoexfoliation syndrome is associated with alterations in the biomechanical properties of the cornea. This prospective observational cohort study aims to evaluate changes in corneal biomechanical properties after standard…
- Trial name
- NCT07719101
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- Kata Culina
Primary Open-angle Glaucoma, Ocular Hypertension
Adherence With Fixed Versus Unfixed Glaucoma Therapy
A 6-month, parallel, non-interventional trial investigating the level of adherence and the impact of dosing in open-angle glaucoma patients who receive either unfixed therapy with latanoprost once in the evening and timolol twice…
- Conditions
- Primary Open-angle Glaucoma, Ocular Hypertension, Exfoliation Glaucoma
- Trial name
- NCT01281020
- Where
- Greece
- Volunteers
- 132 people
- Sponsor
- Aristotle University Of Thessaloniki