Clinical trials: Pseudophakia
Irvine-Gass Syndrome
Treatment of Macular Edema After Cataract Surgery with Subconjunctival Aflibercept
This research study is being conducted to determine the safety and tolerability of subconjunctival injections of aflibercept in the treatment of pseudophakic cystoid macular edema that has not responded well to first-line…
- Trial name
- ACME (NCT03396861)
- Testing
- Aflibercept
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Tufts Medical Center
Pseudophakia, Cataract Surgery
Randomized, Masked Comparison of Bromfenac and Besifloxacin BID With Either Prednisolone BID or Loteprednol 0.5% BID for Prevention of Retinal Thickening and CME Following Phacoemulsification
The purpose of this study is to determine if Lotemax eye drops are at least as effective as Pred Forte eye drops, which are the standard of care after cataract surgery.
- Trial name
- NCT01193504
- Testing
- Pred Forte, Lotemax
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Cataract, Aphakic Eye
Comparative Study of the Tomey OA-2000, Tomey CASIA2, and the LenStar LS900
This is a prospective comparative study that will be conducted at one clinical site in the United States, in which subjects who sign an informed consent form and fulfil all inclusion and exclusion criteria, will have OCT scans…
- Conditions
- Cataract, Aphakic Eye, Pseudophakia
- Trial name
- NCT06065072
- Testing
- Optical measurement
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Tomey Corporation
Pseudophakia
Corrected VA With Long-Term Follow-Up After AcrySof® Intraocular Lens (IOL) Implantation
The purpose of this study is to compare the long-term visual acuity (VA) with an acrylic IOL to a silicone or polymethylmethacrylate (PMMA) IOL in cataract patients. This study will take place in Japan.
- Trial name
- NCT02450799
- Testing
- Acrylic IOL, Silicone IOL, PMMA IOL
- Volunteers
- 104 people
- Sponsor
- Alcon, a Novartis Company
Pseudophakia, Inflammation
Clinical Outcomes and Evaluation of Lotemax 0.5% in Treatment of Ocular Inflammation Associated With Cataract Surgery
Investigate the intraocular pressure(pressure inside the eye) of patients who are treated with Lotemax after undergoing cataract surgery.
- Trial name
- NCT01344226
- Testing
- loteprednol 0.5% ophthalmic solution
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Toyos Clinic
Cataract, Pseudoexfoliation Syndrome
Long-term Intraocular Lens (IOL) Decentration and Tilt in Eyes With Pseudoexfoliation Syndrome (PES) Following Cataract Surgery
To evaluate long-term intraocular lens (IOL) decentration and tilt in eyes with pseudoexfoliation syndrome (PES) following cataract surgery using Visante anterior segment OCT and iTrace Visual Function Analyzer.
- Conditions
- Cataract, Pseudoexfoliation Syndrome, Pseudophakia
- Trial name
- NCT03453827
- Testing
- no intervention
- Volunteers
- 37 people
- Sponsor
- Hospital Hietzing
Presbyopia, Pseudophakia
Synergy Lens Outcomes Evaluation
This is a single visit study to evaluate the visual outcomes and patient satisfaction of patients who were bilaterally implanted with the Tecnis Synergy IOL between June 1 and December 31, 2021 in 2 centers in USA
- Trial name
- NCT05418153
- Testing
- Tecnis Synergy IOL
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- Center For Sight
Lenses, Intraocular, Pseudophakia
Intermediate Vision in a Driving Simulator Environment: Comparison of the J&J EYHANCE With a Conventional Monofoc. IOL
To compare (low contrast) visual acuity (VA) and contrast sensitivity (CS) - both at intermediate distances under nighttime driving conditions in a driving simulator between patients with bilateral EYHANCE IOLs OR bilateral…
- Conditions
- Lenses, Intraocular, Pseudophakia, Near Vision, Driving
- Trial name
- JJ-EYHANCE (NCT04059289)
- Testing
- Posterior chamber intraocular lens (IOL)
- Where
- Germany
- Volunteers
- 11 people
- Sponsor
- Aalen University
Pseudophakia
Visual Outcomes and Patient Satisfaction With Vivity IOL in Post Refractive Patients
This is a non-interventional, prospective, observational study of the outcomes for post myopic refractive surgery patients following successful, uncomplicated cataract surgery with bilateral implantation of the Vivity IOL…
- Trial name
- NCT06064916
- Testing
- Visual Acuity, Defocus Curve, Intraocular Lens Satisfaction (IOLSAT) Questionnaire
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Cataract, Presbyopia
Retrospective Clinical Investigation of the Safety and Performance of 640PM Trifocal IOL Implantation in Patients With Cataract and/or Ametropia (Hyperopia, Myopia) and/or Presbyopia
The clinical investigation objective is to evaluate safety and performance outcomes of trifocal IOL implantation to improve vision in patients with cataract and/or ametropia (hyperopia, myopia) and/or presbyopia.
- Conditions
- Cataract, Presbyopia, Hyperopia, Myopia
- Trial name
- NCT05735990
- Testing
- Intraocular lens
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Medicontur Medical Engineering Ltd
Dry Eye Syndromes
The Effects of BAK on the Blood Aqueous Barrier of Pseudophakic Patients
BAK is one of the most frequent preservatives in eye drops. BAK is a quaternary ammonium salt with surfactant qualities. It can be bacteriostatic or bactericidal depending on the concentrations used.
- Trial name
- NCT01280110
- Testing
- Hydroxypropylmethylcellulose, Carboxymethylcellulose
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Cataract Senile, Pseudophakia
Tecnis Eyhance Versus Rayner RayOne Study
Cataract surgery involves replacing milky lens with a plastic intraocular lens. This plastic lens can be either monofocal (fixates for distance or near without glasses), extended depth of focus (EDOF)(fixates for intermediate and…
- Trial name
- NCT04175951
- Testing
- Intraocular lens
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Posterior Capsule Opacification, Pseudophakia
IOL Position and Refractive Change After Nd:YAG Laser Posterior Capsulotomy
After cataract surgery, the thin natural membrane that holds the artificial lens in place can slowly turn cloudy. This is called posterior capsule opacification. It makes vision blurry and can cause glare.
- Conditions
- Posterior Capsule Opacification, Pseudophakia, Refractive Errors
- Trial name
- YAG-IOL-POS (NCT07802145)
- Testing
- Nd:YAG laser posterior capsulotomy, Anterior segment swept-source OCT, Swept-source optical biometry
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Vienna Hospital Association
Cataract, Pseudophakia
Clinical Outcomes of Patients Implanted With the RxSight Light Adjustable Lens (LAL)
The objective of this investigator initiated study (IIT-002) is to collect data on commercial patients implanted with the RxSight Light Adjustable Lens (LAL).
- Trial name
- NCT06488066
- Testing
- Data collection
- Where
- United States
- Sponsor
- Vance Thompson Vision
Pseudophakia, Refractive Error
IOL Power Formula Prediction Accuracy at the Extremes of Axial Length: A Prospective Outcome Verification Study
This single-center, prospective, cross-sectional study evaluates how accurately eight modern intraocular lens (IOL) power calculation formulas predicted the postoperative refractive result in eyes with extreme axial length after…
- Trial name
- FORMULEX-OV (NCT07724795)
- Testing
- Standardized postoperative outcome visit
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Vienna Hospital Association
Congenital Cataract, Microphthalmos
Biometric Characteristics of the Eye With Microcornea/Microphthalmia and Congenital Cataract Before And After Cataract Extraction
Early cataract surgery in microcornea/microphthalmia eyes is essential to prevent amblyopia and improve visual outcomes, including stereopsis.
- Conditions
- Congenital Cataract, Microphthalmos, Microcornea
- Trial name
- NCT04759560
- Where
- Egypt
- Volunteers
- 133 people
- Sponsor
- Alexandria University
Cataract, Pseudophakia
Correlation Between Sulcus Anatomy and Other Parameters After Horizontal & Vertical Intraocular Lens (IOLs) Placements
Usually following cataract surgery patients would expect to have normal distance vision and not require the use of distance glasses. However, in clinical practice desired vision post cataract surgery is not achieved sometimes.
- Trial name
- NCT04208633
- Testing
- Horizontal placement of the intraocular lens in the capsular bag, Vertical placement of the intraocular lens in the capsular bag
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Cataract
Binocular Vision in Monocular Pseudophakia
Following cataract surgery, an intraocular lens (IOL) is implanted in the eye. The majority of people develop an operable cataract when they are over the age of 50.
- Trial name
- BVMP (NCT01872000)
- Testing
- Cataract surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Oxford
Pseudophakia
The Effects of Angle Kappa on Clinical Outcomes With the PanOptix Intraocular Lens
Angle Kappa is considered a potential factor in explaining suboptimal outcomes with intraocular lenses (IOLs), particularly multifocal IOLs. Some evidence suggests this is not the case.
- Trial name
- NCT04242875
- Testing
- Angle Kappa, Visual disturbance questionnaire.
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Pseudophakia, Hypermetropia
Treatment of Residual Hypermetropic Refraction on Pseudophakic Patients Using Allogenic Fresh Myopic Lenticule
The residual hypermetropic refraction on pseudophakic(Trifocal IOL) patients is difficult to treat surgically. In addition, there are not many suitable options to offer such patients presenting with this condition.
- Conditions
- Pseudophakia, Hypermetropia, Myopia
- Trial name
- ReLex-Smile (NCT04692012)
- Testing
- FRESH CORNEAL MYOPIC LENTICULE IMPLANTATION
- Where
- Kosovo
- Volunteers
- 34 people
- Sponsor
- Eye Hospital Pristina Kosovo