Clinical trials: Pseudotumor
Pseudotumor Cerebri, Cystinosis
The Role of Susceptibility to Thrombosis in the Pseudotumor Cerebri of Nephropathic Cystinosis: A Case-Control Study
This study will examine whether the tendency to have thrombosis, or the formation of blood clots inside blood vessels, has a role in the development of pseudotumor cerebri (PTC).
- Trial name
- NCT00071903
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Polycystic Ovarian Syndrome, Idiopathic Intracranial Hypertension
Astronaut Vision Issues in a Ground Analog Population: Polycystic Ovary Syndrome
The investigators have documented a genetic predisposition for some astronauts to develop ophthalmologic issues (e.g., choroidal folds, cotton wool spots, optic disc edema).
- Trial name
- PCOS (NCT02896452)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Aeronautics and Space Administration
Idiopathic Intracranial Hypertension
Stenting of Venous Sinus Stenosis for Medically Refractory Idiopathic Intracranial Hypertension
Increased Intracranial Hypertension (IIH), also known as Pseudotumor Cerebri, is defined by increased cerebral spinal fluid (CSF) pressure in the absence of intracranial, metabolic, toxic or hormonal causes of intracranial…
- Trial name
- NCT02143258
- Testing
- Stenting of the venous sinus
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Ottawa Hospital Research Institute
Idiopathic Intracranial Hypertension (IIH)
Stenting Of Symptomatic Cerebral siNus stenosIs With the laserCut Self-expanding SILANCE Stent
The objective of this clinical investigation is to evaluate and demonstrate the clinical benefit, performance, and safety of the SILANCE Stent, which is specifically designed for the treatment of patients with symptomatic sinus…
- Trial name
- SONIC (NCT07561268)
- Testing
- SILANCE Stent Implantation
- Volunteers
- 99 people
- Sponsor
- Acandis GmbH
Optic Disc Swelling
Antiacne Medications Pseudotumor Cerebri
The exact incidence of optic disc swelling and idiopathic intracranial hypertension in patients using antiacne medication is not known so far.
- Trial name
- AAMPTC (NCT02149615)
- Testing
- Retinal nerve fibre layer measurement
- Where
- Switzerland
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Haemophilic Pseudotumour
HemLibra Prophylaxis in Patients With Hemophilic Pseudotumor
This is a single arm, phase 4, prospective, open-label, United States single-center study to assess the hemostatic efficacy and safety of Hemlibra (emicizumab) for hemostatic control of hemophilia A patients (baseline FVIII level…
- Trial name
- NCT03921294
- Testing
- Emicizumab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana Hemophilia &Thrombosis Center, Inc.
Idiopathic Intracranial Hypertension
Assessment of ICP in Idiopathic Intracranial Hypertension Using Transocular Ultrasound and Transcranial Doppler
Idiopathic Intracranial Hypertension (IIH) is a rare disease, primarily affecting overweight females of child-bearing age. Patients suffer from increased intracranial pressure (ICP), typically resulting in headaches, visual…
- Trial name
- NCT04314128
- Testing
- TOS and TCD
- Where
- Denmark
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Eye Change, Idiopathic Intracranial Hypertension
ICP & Outflow Study
This study aims to investigate the relationship between intracranial pressure (ICP) and aqueous outflow (the flow of the eye's internal fluid out of the eye), in patients with increased intracranial pressure (idiopathic…
- Trial name
- NCT06436820
- Testing
- Lumbar puncture
- Volunteers
- 66 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pseudotumor Cerebri, Cerebrospinal Fluid
Stenting Versus Neurosurgical Treatment of Idiopathic Intracranial Hypertension.
Idiopathic intracranial hypertension (HTICi) is a pathology, affecting young adults with a predominance of women, due to an increase in intracranial pressure, which may be associated with stenosis of the cerebral venous sinuses…
- Conditions
- Pseudotumor Cerebri, Cerebrospinal Fluid, Transverse Sinuses
- Trial name
- HYDROPTIC (NCT05050864)
- Testing
- venous sinus stenting, Neurosurgical internal ventricular shunt
- Where
- France
- Volunteers
- 276 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Idiopathic Intracranial Hypertension (IIH)
Venous Stenting Evaluation in Patients With Intracranial Hypertension Under Long-term Acetazolamide
This study is aimed at patients suffering from long term intracranial hypertension (caracterized by visual loss, chronic headache and/or tinnitus), receiving acetazolamide for more than 1 year, having inadequate response to…
- Trial name
- DIVEIINLATE (NCT06945848)
- Testing
- Acetazolamide, Stent (Tentos 4F or Precise ProRX)
- Where
- 3 sites in France
- Volunteers
- 114 people
- Sponsor
- University Hospital, Montpellier
Idiopathic Intracranial Hypertension (IIH)
VEHICLE Registry: Venous Stenting for IIH in the MENA Region
The VEHICLE Registry is a multicenter observational study aimed at evaluating the management and outcomes of patients with Idiopathic Intracranial Hypertension (IIH) undergoing venous sinus stenting in the Middle East and North…
- Trial name
- VEHICLE (NCT06692790)
- Testing
- Venous Sinus Stenting Procedure
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 150 people
- Sponsor
- Middle East North Africa Stroke and Interventional Neurotherapies Organization
Orbital Tumor, Orbital Pseudotumor
MRI and Orbital Tumours (MEDORT)
Orbital masses develop at the expense of the orbital structures lacrimal glands, oculomotor muscles, optic nerve, meningeal spaces, peripheral nerves, bone wall, orbital fat, lymphoid structures or vascular structures.
- Trial name
- MEDORT (NCT02401906)
- Testing
- MRI
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Pseudotumor Cerebri, Idiopathic Intracranial Hypertension (IIH)
Operative Procedures Vs. Endovascular Neurosurgery for Untreated Pseudotumor Trial
Pseudotumor cerebri, also called idiopathic intracranial hypertension (IIH), is characterized by elevated intracranial pressure, headache, and if severe, vision loss. IIH is difficult to treat.
- Trial name
- OPEN-UP (NCT02513914)
- Testing
- Dural Venous Sinus Stenting, Cerebrospinal Fluid Shunting
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Idiopathic Intracranial Hypertension
An RCT of Bariatric Surgery vs a Community Weight Loss Programme for the Sustained Treatment of IIH
Idiopathic intracranial hypertension (IIH) is a condition with an unknown cause or causes. The condition is associated with raised pressure in the brain and can cause disabling daily headaches and loss of sight, which can be…
- Trial name
- IIH:WT (NCT02124486)
- Testing
- Bariatric surgery, Dietetic intervention
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Hydrocephalus, Idiopathic Intracranial Hypertension
Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement
This research is being done to determine the accuracy of two noninvasive methods of measuring the pressure of the cerebrospinal fluid (CSF), also known as intracranial pressure or ICP.
- Conditions
- Hydrocephalus, Idiopathic Intracranial Hypertension, Pseudotumor Cerebri
- Trial name
- NCT01863381
- Testing
- Tympanic membrane displacement (TMD), DPOAE
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- LifeBridge Health
Idiopathic Intracranial Hypertension, Intracranial Pressure
The Effect of an Anti-obesity Drug, Semaglutide, as Treatment in New-onset Idiopathic Intracranial Hypertension (IIH) Compared to Standard Weight Management (Dietician) With Regards to Change in Weight and Intracranial Pressure
50 patients with verified new-onset Idiopathic Intracranial Hypertension are randomly allocated to standard weight management (dietician counselling) or trial intervention consisting of subcutaneous injections with Semaglutide…
- Conditions
- Idiopathic Intracranial Hypertension, Intracranial Pressure, Obesity, Pseudotumor Cerebri Syndrome
- Trial name
- IIH:DUAL (NCT06027567)
- Testing
- Semaglutide, Very Low Calorie Diet, Dietician counselling
- Where
- 2 sites in Denmark
- Volunteers
- 38 people
- Sponsor
- Rigmor Højland Jensen
IIH - Idiopathic Intracranial Hypertension
Current Treatment Methods of Idiopathic Intracranial Hypertension
Aim of the study : 1. to determine the response to each treatment plan. 2. to determine when to choose specific treatment method. 3. to determine complication of each type of treatment method
- Trial name
- NCT06353412
- Testing
- Lumbar puncture
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Assiut University