Clinical trials: Psoriasis Patients
Psoriasis
A Study to Evaluate the Safety and Efficacy of Efalizumab in Adult Patients With Moderate to Severe Plaque Psoriasis With Involvement of the Scalp
This was a Phase IV randomized, double-blind, placebo-controlled study designed to evaluate the safety and efficacy of subcutaneous efalizumab in adult patients (18 years of age and older) with chronic moderate to severe plaque…
- Trial name
- SCALP (NCT00669214)
- Testing
- efalizumab
- Volunteers
- 89 people
- Sponsor
- Genentech, Inc.
Spondylarthropathies, Ankylosing Spondylitis
TNFalfa Blocking Treatment of Spondylarthropathies
The purpose of the study is to establish a Danish cohort of spondylarthropathy (SpA) patients who are being treated with TNFalfa blockers.
- Conditions
- Spondylarthropathies, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- NCT00133315
- Testing
- Infliximab, Etanercept, Adalimumab
- Where
- 9 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Hvidovre University Hospital
Rheumatoid Arthritis, Psoriatic Arthritis
COVID-19 VaccinE Response in Rheumatology Patients
The COVID-19 VaccinE Response in Rheumatology patients (COVER) study is a multicenter randomized controlled trial designed to evaluate the efficacy and safety of a mRNA COVID-19 vaccine supplemental dose (booster) in patients…
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Spondylarthritis
- Trial name
- COVER (NCT05080218)
- Testing
- Upadacitinib, Abatacept, Secukinumab
- Where
- 8 sites in United States
- Volunteers
- 841 people
- Sponsor
- Jeffrey Curtis
Plaque Psoriasis
Clinical Study to Evaluate the Efficacy and Safety of DSXS in Patients With Mild to Moderate Plaque Psoriasis
The purpose of this study is to evaluate the therapeutic efficacy and safety of DSXS compared to a Placebo (vehicle) in patients with mild to moderate plaque psoriasis.
- Trial name
- NCT02618759
- Testing
- DSXS
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Psoriasis, Psoriatic Arthritis
Prevalence and Incidence of Articular Symptoms and Signs Related to Psoriatic Arthritis in Patients With Psoriasis Severe or Moderate With Adalimumab Treatment
Psoriatic Arthritis (PsA) is a comorbidity that affects a significant proportion of participants with moderate or severe psoriasis.
- Trial name
- TOGETHER (NCT01316224)
- Where
- 15 sites in Colombia
- Volunteers
- 52 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Plaque Psoriasis
Real-life Evaluation of the Daivobet® Gel Applicator
This study aims to describe the patient population being treated and evaluate their treatment adherence and treatment outcomes during treatment of scalp psoriasis with Daivobet® gel Applicator for 4 weeks.
- Trial name
- ASAP PSO (NCT02856542)
- Testing
- calcipotriol/betamethasone dipropionate gel in Applicator
- Where
- France
- Volunteers
- 1,560 people
- Sponsor
- LEO Pharma
Psoriatic Arthritis
Efficacy of Secukinumab Compared to Adalimumab in Patients With Psoriatic Arthritis
This was a randomized, double-blind, active controlled, multicenter, parallel-group study evaluating secukinumab monotherapy and adalimumab monotherapy in approximately 850 patients with active psoriatic arthritis (PsA) who are…
- Trial name
- EXCEED 1 (NCT02745080)
- Testing
- Secukinumab, Adalimumab
- Where
- 156 sites in United States, Australia and 24 more
- Volunteers
- 853 people
- Sponsor
- Novartis Pharmaceuticals
Psoriasis Vulgaris
Therapeutic Drug Monitoring of Guselkumab in Psoriasis Patients
Biologic such as guselkumab are currently the most effective treatment option for patients with moderate to severe psoriasis. But they are costly for healthcare systems and still described according to a 'one dose fits all'…
- Trial name
- BIOLOPTIM-GUS (NCT04080648)
- Testing
- Venapuncture, Patient questionnaires
- Where
- 7 sites in Belgium
- Volunteers
- 79 people
- Sponsor
- University Hospital, Ghent
Psoriasis
Topical Psoriasis Study for Patients Receiving Biologic Therapy
A two-phase, single center, study of 20 subjects to assess 4 weeks of add-on therapy of Topicort® BID and 12 weeks BID on two consecutive days a week to patients with ≤5% BSA who are receiving biologic therapy for at least 24…
- Trial name
- NCT02983981
- Testing
- Topicort Topical Spray
- Volunteers
- 20 people
- Sponsor
- Psoriasis Treatment Center of Central New Jersey
Eczema, Psoriasis
Use of a Digital Psychotherapeutic App to Reduce Symptom Burden in Dermatology Patients
Skin diseases, despite low mortality, significantly impair quality of life. This randomised controlled trial evaluates the efficacy of a digital toolkit comprising psychotherapeutic strategies in reducing QoL burden in patients…
- Conditions
- Eczema, Psoriasis, Urticaria
- Trial name
- NCT06702293
- Testing
- Digital psychotherapeutic intervention, Healthy365
- Where
- Singapore
- Volunteers
- 690 people
- Sponsor
- National University Hospital, Singapore
Plaque Psoriasis
Assessment on Efficacy and Safety of BAT2306 and Cosentyx® in Plaque Psoriasis Patients
This study is a multicenter, randomized, double-blind, parallel-arm, Phase 3 study designed to compare efficacy, safety, immunogenicity, and PK of BAT2306 with Cosentyx in patients with moderate to severe plaque psoriasis.
- Trial name
- NCT05377944
- Testing
- BAT2306, EU-approved Cosentyx
- Where
- China
- Volunteers
- 502 people
- Sponsor
- Bio-Thera Solutions
Plaque Psoriasis
To Evaluate the Efficacy and Safety of Netakimab in Chinese Patients With Moderate to Severe Plaque Psoriasis
The goal of this clinical trial is to To evaluate the efficacy of subcutaneous (SC) Netakimab in adult Chinese patients with moderate to severe plaque psoriasis.
- Trial name
- NCT07008547
- Testing
- Netakimab
- Where
- China
- Volunteers
- 202 people
- Sponsor
- SPH-BIOCAD (HK) Limited
Psoriasis
An Open-label Study to Evaluate the Efficacy of Re-treatment for Patients With a History of Etanercept Use
The purpose of this study is to evaluate the efficacy of re-treatment with etanercept 50mg subcutaneous injections twice weekly for 12 weeks in subjects who have previously been treated etanercept and efficacy diminished.
- Trial name
- ENBRECAP2009 (NCT01132235)
- Testing
- etanercept
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Florida Academic Dermatology Centers
Plaque Psoriasis
A Study to Evaluate Clear Skin Effect on Quality of Life in Patients With Plaque Psoriasis.
Study of effects of secukinumab 300 mg s.c. on quality of life (QoL) in psoriasis in patients with or without prior exposure to systemic therapy.
- Trial name
- PROSE (NCT02752776)
- Testing
- Secukinumab
- Where
- 215 sites in Belgium, Bulgaria and 15 more
- Volunteers
- 1,660 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Plaque Psoriasis
Skin Transcriptional Profiles In Psoriatic Patients Under Adalimumab Biotherapy
The expertise in the characterization of transcriptomics profile in lesional psoriatic skin and on the availability of innovative therapy for these patients.The investigators propose to follow the modification of the skin…
- Trial name
- CYTOPSO (NCT01872546)
- Testing
- Adalimumab Every Week
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Poitiers University Hospital
Plaque Psoriasis
CF101 Therapy in Patients With Moderate-to-severe Plaque Psoriasis
This trial will test the hypothesis that the administration of CF101, a novel anti-inflammatory agent, to patients with moderate to severe plaque psoriasis will relieve signs and symptoms of the disease.
- Trial name
- NCT03168256
- Testing
- CF101 2mg, CF101 3mg, Apremilast 30mg
- Where
- 30 sites in Bosnia and Herzegovina, Bulgaria and 7 more
- Volunteers
- 528 people
- Sponsor
- Can-Fite BioPharma
Psoriasis Vulgaris
Oral and Topical Phytocannabinoids for Psoriasis
Psoriasis is a chronic inflammatory skin disease that affects approximately 2% of the global population and is frequently associated with psychiatric comorbidities such as anxiety and depression.
- Trial name
- CBDermis (NCT07839455)
- Testing
- Oral Cannabis Extract, Topical cannabis cream
- Where
- Brazil
- Volunteers
- 37 people
- Sponsor
- Federal University of Latin American Integration
Psoriasis
Anti-psoriatic Effect of TL01 Light Therapy
This is a pilot study to investigate the effect of TL01 narrow band UVB therapy on the resident dermal dendritic cells characterized by expression of CD1c and CD141.
- Trial name
- NCT02599415
- Testing
- TL01 light treatment
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- University of Aberdeen
Psoriasis
Secukinumab in Tumor Necrosis Factor (TNF) - Inadequate Response (IR) Psoriasis Participants.
This study was designed to prove and quantify the hypothesis that secukinumab is effective, safe and well tolerated in the treatment of moderate to severe chronic plaque-type psoriasis in patients who are inadequate responders to…
- Trial name
- SIGNATURE (NCT01961609)
- Testing
- Secukinumab (AIN457)
- Where
- 54 sites in Ireland, United Kingdom
- Volunteers
- 235 people
- Sponsor
- Novartis Pharmaceuticals
Ankylosing Spondylitis, Psoriatic Arthritis
Multi-country Post-Marketing Observational Study on Maintenance of Effectiveness of Adalimumab (Humira®) in Patients With Ankylosing Spondylitis and Psoriatic Arthritis
This 12-month postmarketing observational study (PMOS) was a prospective, single-arm, multicenter, multi-country study, with follow-up visits at 3, 6, 9, and 12 months after the initial baseline visit.
- Trial name
- NCT01474876
- Volunteers
- 566 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
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