Clinical trials: Psychiatric Disorder
Alzheimer Dementia, Alzheimer Disease
SAD Phase I Study (First-in-human) to Investigate Contraloid Acetate
This is a single-center first-in-human single-ascending-dose clinical trial assessing the safety and tolerability of oral dosing of Contraloid acetate in healthy volunteers.
- Trial name
- NCT03944460
- Testing
- Contraloid
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Dieter Willbold
Cancer, Chemotherapy Effect
The Effect of the Art-based Mandala Intervention on the Quality of Life of Cancer Patients Receiving Chemotherapy
The aim of this study is to determine the effect of mandala application on fatigue, quality of life, rumination and alexithymia in cancer patients receiving chemotherapy.
- Conditions
- Cancer, Chemotherapy Effect, Fatigue, Quality of Life
- Trial name
- ARQULA (NCT05344820)
- Testing
- Art based mandala
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Alzheimer's Disease
Deep Brain Stimulation for the Treatment of Alzheimer's Disease
The purpose of this clinical study is to investigate the safety and efficacy of deep brain stimulation (DBS)as a treatment option for patients with cognitive, behavioral, and functional disability of Alzheimer's disease.
- Trial name
- NCT01559220
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Ali Rezai, MD
Delirium and Post-operative Cognitive Dysfunction (POCD)
Cognitive Outcome After Two-stage Liver-Operation
Cognitive outcome (delirium and post-operative cognitive deficiency) in patients undergoing two-time liver resection.
- Trial name
- 2-StaLi (NCT01809782)
- Where
- Germany
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Chronic Sleep Disorders, Anxiety Disorder
Effect of Transcranial Alternating Current Stimulation on Sleep Disorder and Anxiety in Elderly Population
Sleep disorders and anxiety are complicated disorders affecting population especially elderly population, therefore treating these disorders will have positive impact on population production and quality of life.
- Trial name
- NCT07147582
- Testing
- Transcranial alternating current stimulation with two electrodes placed on scalp
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Covid-19
COVID-19 Virtual Care at Home
This multicentre prospective cohort trial is designed to demonstrate effectiveness and efficiency of a virtual care model for the management of COVID-19 patients isolating at home.
- Trial name
- NCT04420182
- Testing
- Virtual Care at Home
- Where
- 5 sites in Canada
- Volunteers
- 817 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Intellectual Disability
Study of Mindfulness Course for Parents of Adults With Intellectual Disabilities
Being a parent to an adult person with learning disabilities can be very stressful, and can lead to experiencing mental health problems.
- Trial name
- NCT04294082
- Testing
- Mindfulness based intervention
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Edinburgh
Single-ventricle, Posttraumatic Stress Disorder
The PaTHS Descriptive Correlational Longitudinal Study
The primary objective of this study is to measure parent's post-traumatic stress before and after their infant's second palliative heart surgery for single ventricle congenital heart disease.
- Conditions
- Single-ventricle, Posttraumatic Stress Disorder, Psychosocial Impairment
- Trial name
- PaTHS (NCT04785482)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Children's Mercy Hospital Kansas City
Anxiety
Effects of Stress Ball Use on Heart Rate Variability, Anxiety, and Pain During Awake Hand Surgery: A Randomized Controlled Trial
Preoperative anxiety begins from the decision-making of surgery to entering the operating room and may intensify as the surgery date approaches.
- Trial name
- NCT06742814
- Testing
- stress ball
- Where
- 2 sites in Taiwan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Alzheimer Disease
Impact of Therapeutic Educational Programme on the Alzheimer's Disease Affected Patient's Quality of Life
Therapeutic education expands in Alzheimer's Disease management in France. Several studies revealed a positive impact on caregiver's burden and/or quality of life.
- Trial name
- THERAD (NCT01796314)
- Testing
- Therapeutic Educational Program
- Where
- France
- Volunteers
- 170 people
- Sponsor
- University Hospital, Toulouse
Nicotine Dependence, Major Depressive Disorder
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers
Persons who struggle with depression smoke at high rates and experience low quit rates in treatment. The best way to improve cessation treatment for this underserved population remains unknown.
- Trial name
- NCT02378714
- Testing
- Varenicline, BASC, Standard treatment
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Sleep Disorder, Lung Tumor
Effect of Sleep Disorder on the Development of Lung Tumors
The goal of this observational study is to observe the lung tumor development in lung tumor patients with long-term sleep disorder.
- Trial name
- NCT05745506
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Schizophrenia
Study Evaluating Vabicaserin in Subjects With Schizophrenia
The primary purpose of this protocol is to establish the efficacy, safety, and tolerability of vabicaserin (SCA-136) using a once a day capsule in subjects with acute exacerbations of schizophrenia.
- Trial name
- NCT00563706
- Testing
- vabicaserin, risperidone
- Where
- 33 sites in United States, Canada
- Volunteers
- 199 people
- Sponsor
- Pfizer
Posttraumatic Stress Disorder
MGH Trauma-related Nightmares SDI Study
Interested individuals will first complete a telephone screening followed by a series of structured clinical interviews to diagnose PTSD and comorbid psychiatric disorders, confirm initial inclusion criteria, rule out exclusion…
- Trial name
- NM (NCT05195684)
- Testing
- imaginal probe
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
ADHD
A Trial to Assess How Centanafadine Interacts With Stimulants in the Body
This study will look at how centanafadine works when taken together with stimulant medicines in healthy adults, and whether combining them affects how the body responds.
- Trial name
- NCT07314333
- Testing
- Centanafadine, Methylphenidate, Lisdexamfetamine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Chronic Migraine
Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial
Chronic headaches are a major cause of disability among adolescents. Cannabis products have supported the management of headaches in adults and may play a role in pediatric chronic pain.
- Trial name
- CAN-CHA (NCT05337033)
- Testing
- MPL-001
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Moderate or Severe Opioid Use Disorder
A Multiple Dose Opioid Challenge Study
Multi-site, randomized, double-blind, repeat-dose Phase 2 study to evaluate the degree and duration of action of multiple doses of CAM2038 in blocking the effects of hydromorphone in patients with moderate or severe opioid use…
- Trial name
- NCT02611752
- Testing
- CAM2038
- Where
- 3 sites in United States
- Volunteers
- 47 people
- Sponsor
- Braeburn Pharmaceuticals
Prodromal Schizophrenia, Prodromal Psychosis
Aripiprazole Treatment of the Prodrome
The RAP Program is conducting a research study of the antipsychotic medication Aripiprazole. This drug has been approved for treating symptoms associated with schizophrenia and is associated with fewer side effects.
- Trial name
- NCT00169949
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Schizophrenia and Related Disorders, Drug Administration Schedule
"Extended" (Alternate Day) Antipsychotic Dosing
The study wishes to examine whether "extended" antipsychotic treatment, in this case, antipsychotic treatment every other day, is as effective as daily treatment.
- Conditions
- Schizophrenia and Related Disorders, Drug Administration Schedule, Drug Therapy, Antipsychotic Agents
- Trial name
- NCT04478838
- Testing
- Risperidone, Olanzapine, paliperidone
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Centre for Addiction and Mental Health
Mental Disorders, Drug Addiction
Treatment of Hepatitis C in Psychiatric Patients
Psychiatric disorders or drug addiction are often regarded as contraindications against the use of Interferon-alpha in patients with chronic hepatitis C.
- Trial name
- NCT00751426
- Where
- Germany
- Volunteers
- 81 people
- Sponsor
- Charite University, Berlin, Germany