Clinical trials: Psychiatric Disorder
Dementia, Staff Attitude
Speeko for Elderspeak: A Self-Monitoring App to Improve Nursing Home Communication
This study will test feasibility and preliminary effects of an automated and performance-based feedback app (Speeko for Elderspeak) that detects and reports the use of diminutives (terms of endearment such as honey, dearie, and…
- Trial name
- NCT04064164
- Testing
- Speeko for Elderspeak
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Schizophrenia
Addition of Ondansetron to Ongoing Antipsychotic Treatment for Schizophrenia
This study will examine the effects of ondansetron on auditory nerve activity in people with schizophrenia who are being treated with new antipsychotics.
- Trial name
- NCT00149734
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Colorado, Denver
Cocaine Dependence
Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
Cocaine use disorders affect approximately 1.5 million Americans annually. Currently, there are no US Food and Drug Administration approved medications for treatment of cocaine dependence; however, both animal and human studies…
- Trial name
- NCT01953432
- Testing
- Doxazosin
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Major Depressive Disorder
Psilocybin-assisted CBT for Depression
The primary objectives of this clinical investigation are to (1) determine the acceptability and feasibility of joining psilocybin-assisted therapy with cognitive-behavioral therapy (PA-CBT) for patients with depression, (2)…
- Trial name
- NCT05227612
- Testing
- Psilocybin, Cognitive behavioral therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of California, Los Angeles
Bipolar Disorder, Major Depressive Disorder
Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms
The purpose of this study is to advance a non-pharmacologic suicide preventive intervention with wide dissemination potential as an innovative high-yield solution to reduce suicide rates.
- Conditions
- Bipolar Disorder, Major Depressive Disorder, Mood Disorders, Suicide
- Trial name
- NCT05317481
- Testing
- BE-SMART-DR, psychoeducational control comparator condition (CC)
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Yale University
Sexual Dysfunction, Bipolar Disorder
Study of Maca Root to Treat Sexual Dysfunction Associated With the Treatment Regimen for Bipolar Disorder in Females
The purpose of this research study is to find out whether Maca Root is effective for treating sexual dysfunction in females that is caused by the treatment for bipolar disorder.
- Trial name
- NCT00575328
- Testing
- Maca Root
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Alzheimer Disease
Non-invasive Blood-brain Barrier Opening in Alzheimer's Disease Patients Using Focused Ultrasound
The purpose of this study is to test a new technique that may, in the future, help deliver medications to the brain of people with Alzheimer's disease.
- Trial name
- NCT04118764
- Testing
- Neuronavigation-guided single-element focused ultrasound transducer, Definity, Magnetic Resonance Imaging (MRI) with or without gadolinium contrast agents
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Columbia University
Posttraumatic Stress Disorder, Depression
Behavioral Activation for PTSD/Depression Treatment in OIF/OEF Veterans
The present study is a randomized, controlled trial that compares Behavioral Activation (BA) to Treatment As Usual (TAU) in PTSD Specialty clinics, as early psychotherapeutic interventions for OIF/OEF veterans with posttraumatic…
- Trial name
- NCT00805532
- Testing
- Behavioral Activation treatment, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
Sedentary Lifestyle, Dementia, Mild
Smartphone App to Improve Physical Activity in Older Adults With MCI/Mild Dementia
The purpose of this study is to develop and test a physical activity-tracking smartphone app designed to facilitate physical activity in older adults with mild cognitive impairments or mild dementia.
- Conditions
- Sedentary Lifestyle, Dementia, Mild, Mild Cognitive Impairment, Memory and Thinking Problems
- Trial name
- NCT04950998
- Testing
- Moving Up - A
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Southern California
Schizophrenia
A Study to Compare the Pharmacokinetics Profile of DWCZP Tablet 100mg and Clozaril® Tablet 100mg
To evaluate the pharmacokinetics of oral multiple-dose of DWCZP tablet 100mg.
- Trial name
- DWCZP-I-1 (NCT01654601)
- Testing
- DWCZP, Clozaril
- Where
- 5 sites in South Korea
- Volunteers
- 28 people
- Sponsor
- Dong Wha Pharmaceutical Co. Ltd.
Anorexia Nervosa
Shifting Perspectives: Enhancing Outcomes in Anorexia Nervosa With CRT
Anorexia Nervosa is a serious life-threatening illness with a typical age of onset in adolescence; if not effectively treated, it has the potential to significantly impact adolescent development and quality of life.
- Trial name
- NCT03928028
- Testing
- Cognitive Remediation Therapy, Family Based Treatment
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Children's Hospital of Philadelphia
Schizophrenia, Schizoaffective Disorder
Biomarkers in Schizophrenia
N-methyl-D-aspartate (NMDA)-type glutamate receptors are thought to play a pivotal role in neurocognitive dysfunction associated with schizophrenia.
- Trial name
- NCT00817336
- Testing
- D Serine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research
Gambling Addiction, Gambling Disorder
The Effect of Self Stigma Tailored Cognitive Behavioral Therapy on Gambling Disorder
The goal of this clinical trial was to evaluate whether a cognitive behavioral therapy (CBT) program focused on self-stigma could help reduce both self-stigma and gambling disorder severity in adults diagnosed with gambling…
- Conditions
- Gambling Addiction, Gambling Disorder, Gambling Disorder Treatment, Stigma
- Trial name
- NCT06943963
- Testing
- Self Stigma Tailored Cognitive Behavioral Therapy on Gambling Disorder, standart pharmacotherapy, motivational intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ege University
Huntington's Disease
Examination of Quantitative Electroencephalographic (QEEG) Biomarkers in Huntington's Disease
The pace of basic science research defining the mechanisms of selective neuronal degeneration in Huntington disease (HD) has far exceeded the pace of translation of this information into clinically effective treatments for the…
- Trial name
- HD (NCT00670709)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Schizophrenia
Implementing mHealth for Schizophrenia in Community Mental Health Settings
Randomized control trial examining two mHealth intervention strategies.
- Trial name
- NCT04147897
- Testing
- FOCUS
- Where
- 8 sites in United States
- Volunteers
- 299 people
- Sponsor
- University of Washington
Schizophrenia
Patient-Centered Medication Adherence Intervention for Schizophrenia
Efficacious antipsychotic medication treatments for schizophrenia are available; however , antipsychotic regimens frequently do not achieve their potential because of poor medication adherence.
- Trial name
- AMAIS (NCT00144027)
- Testing
- Antipsychotic medication adherence intervention
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- US Department of Veterans Affairs
Mild Cognitive Impairment
Cognitive Training and Practice Effects in Mild Cognitive Impairment
The current study will test the effectiveness of a computerized cognitive training program on auditory memory and attention in patients with mild cognitive impairment.
- Trial name
- NCT02301546
- Testing
- computerized cognitive exercises
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- University of Utah
Autism Spectrum Disorder
Expediting Access to Services for Equity
The goal of this clinical trial is to assess whether telehealth-based Family Navigation (FN) expedites enrollment (e.g., reduces time in days) in community-based autism intervention for Black toddlers under the age of 4 after…
- Trial name
- EASE (NCT06291246)
- Testing
- Virtual Family Navigation, Educational Materials
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of North Carolina, Chapel Hill
Agitation, Dementia
Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY III)
A study to determine the safety and efficacy of BXCL501 dosing for episodes of agitation associated with dementia when they occur (given as needed [PRN]), for a maximum of 168 doses within a 12-week treatment period.
- Trial name
- NCT05665088
- Testing
- BXCL501
- Where
- 7 sites in United States
- Volunteers
- 13 people
- Sponsor
- BioXcel Therapeutics Inc
Pathological Gambling
Topiramate in the Treatment of Pathological Gambling
This study will assess the efficacy of topiramate in the treatment of pathological gambling. Pathological gambling (PG) is a debilitating disorder, generally leading to severe personal, familial, financial, social, and…
- Trial name
- NCT00245583
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
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