Clinical trials: Psychiatric Disorder
Premenstrual Dysphoric Disorder
Continuous Oral Contraceptive Treatment in Premenstrual Dysphoric Disorder (PMDD)
The purpose of this study is to compare a low dose oral contraceptive (OC) given continuously (every day for three months) with the same low dose oral contraceptive given in an interrupted regimen (one week of inactive placebo…
- Trial name
- PMDD (NCT00927095)
- Testing
- Continuous OC (EE/DROS), Intermittent OC (EE/DROS)
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of North Carolina, Chapel Hill
PTSD
Supported Education Pilot
The goal of this project is to gather data necessary for a full scale trial of a supported education service for OIF/OEF veterans with PTSD.
- Trial name
- SEd (NCT01073657)
- Testing
- Supported Education, General Peer Support
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Major Depressive Disorder
Biomarkers in Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent Depression
The Researchers are going to gather information regarding the use of rTMS as a treatment for depression in adolescents with Major Depressive Disorder.
- Trial name
- NCT03363919
- Testing
- NeuroStar TMS Therapy® System, NeuroStar XPLOR®
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Mayo Clinic
ADHD, Sleep
Sleep IntervEntion as Symptom Treatment for ADHD
Up to 72% of adolescents with ADHD portray sleep problems. The most common sleep difficulties in adolescents with ADHD are initial insomnia, nocturnal awakenings, non-restorative or restless sleep.
- Conditions
- ADHD, Sleep, Adolescents, CBT
- Trial name
- SIESTA (NCT04723719)
- Testing
- SIESTA, Treatment as usual for ADHD
- Where
- Belgium
- Volunteers
- 92 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Huntington Disease, Irritability
Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease
The purpose of this study is to assess efficacy and safety of dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg) in patients with irritability due to Huntington's disease.
- Trial name
- NCT03854019
- Testing
- Dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Tobacco Smoking, Smoking Behaviors
Human Perception of Odors and Odor Blockers
The goal of this clinical trial is to determine whether blockers of perception of key odorants in cigarette smoke have any utility in smoking cessation.
- Trial name
- NCT06191419
- Testing
- Odorants
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Tim McClintock
Major Depressive Disorder
Spinal Cord Stimulation for the Treatment of Major Depressive Disorder
This pilot clinical trial will evaluate the efficacy and safety of transcutaneous direct current stimulation (tsDCS) in major depressive disorder.
- Trial name
- SPIDEP (NCT03433339)
- Testing
- Active transcutaneous spinal direct current stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Parkinson Disease
A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment
This study will evaluate the safety, tolerability, and potential effects on cognition of GRF6021, a plasma-derived product, administered as an intravenous (IV) infusion, to subjects with Parkinson's disease and cognitive…
- Trial name
- NCT03713957
- Testing
- GRF6021
- Where
- 29 sites in United States, Australia and 1 more
- Volunteers
- 79 people
- Sponsor
- Alkahest, Inc.
Schizophrenia, Stress Disorders, Post-Traumatic
Optimizing Cognitive Remediation
Veterans with mental illness face challenges with community reintegration, including achieving vocational success, attaining their educational goals and going back to school, and maintaining a high quality of life.
- Conditions
- Schizophrenia, Stress Disorders, Post-Traumatic, Generalized Anxiety Disorder, Mood Disorders
- Trial name
- NCT04395157
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Office of Research and Development
Substance Use Disorders
The Effect of a Contingency Management Intervention on Substance Use
Contingency management interventions involve providing a tangible reward for progress toward treatment goals. The purpose of this study is to determine whether a contingency management intervention added to usual care leads to…
- Trial name
- REAP (NCT00252512)
- Testing
- Contingency Management
- Where
- 2 sites in United States
- Volunteers
- 332 people
- Sponsor
- VA Office of Research and Development
Sleep Disorders, Fibromyalgia
The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia
Fibromyalgia is a condition of chronic widespread pain, sleep disturbance and fatigue. Most of the patients with fibromyalgia complain of either non-restorative sleep or complaints of disturbed sleep due to pain.
- Conditions
- Sleep Disorders, Fibromyalgia, Sleep
- Trial name
- NCT01234675
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Mansoor Ahmed M.D.
Pathological Gambling
Clinical Study to Determine if Ecopipam Can Reduce Urges to Gamble
This study is designed to test the hypothesis that ecopipam is able to reduce urges to gamble in patients diagnosed with Pathological Gambling.
- Trial name
- NCT01215357
- Testing
- Ecopipam
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- Emalex Biosciences Inc.
Bipolar I Disorder, Bipolar II Disorder
Sequential Multiple Assignment Treatment for Bipolar Disorder
The purpose of this study is to compare which of the two mood stabilizers (drugs that help to steady/stabilize mood in patients with bipolar disorder (BD)), lithium and divalproex, is more effective in patients with bipolar…
- Trial name
- SMART (NCT01588457)
- Testing
- Lithium, Divalproex, Lamotrigine
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Cognitive Disorders
Clinical Trial of Efficacy and Safety of MMH-MAP in the Treatment of Cognitive Disorders
The clinical trial to valuate efficacy and safety of MMH-MAP in the treatment of cognitive disorders in patients with ischemic stroke in the carotid arteries.
- Trial name
- NCT04295681
- Testing
- MMH-MAP
- Where
- 22 sites in Russia
- Volunteers
- 246 people
- Sponsor
- Materia Medica Holding
Alcohol Dependence
Glutamatergic Modulation of Disordered Alcohol Use
Alcohol use disorders remain a significant public health problem. The pharmacological facilitation of behavioral treatment represents a promising strategy for addressing disordered drinking.
- Trial name
- NCT02539511
- Testing
- CI-581a, CI-581b, Motivational Enhancement Therapy (MET)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- New York State Psychiatric Institute
Opiate Dependence, Chronic Pain
Repetitive Transcranial Magnetic Stimulation for Opiate Use Disorder
This double-blind, randomized, controlled trials will investigate the effect of accelerated, repeated transcranial magnetic stimulation on opiate craving and perceived pain .
- Trial name
- ArTMS (NCT03538444)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Medical University of South Carolina
Anxiety Disorders
Efficacy and Safety Study of Seroquel SR in the Treatment of Generalised Anxiety Disorder
The primary purpose of this study is to evaluate whether treatment with (SEROQUEL SR) quetiapine fumarate sustained release (SR) for 9 weeks compared to placebo will improve elderly patients with generalised anxiety disorder.
- Trial name
- NCT00389064
- Testing
- Quetiapine XR
- Where
- 43 sites in United States, Estonia and 3 more
- Volunteers
- 450 people
- Sponsor
- AstraZeneca
Post-Traumatic Stress Disorder
Safety and Efficacy of NYX-783 in Subjects With Post-Traumatic Stress Disorder
To evaluate the safety, tolerability, and response profile of NYX-783 in a Post-Traumatic Stress Disorder population.
- Trial name
- NCT04044664
- Testing
- NYX-783
- Where
- 37 sites in United States
- Volunteers
- 160 people
- Sponsor
- Aptinyx
Depressive Disorder, Major
A Study of Adjunctive Treatment to Antidepressant Therapy for Adults With Major Depressive Disorder
The primary purpose is to study the efficacy, safety, and tolerability of LY2216684 as an adjunctive treatment for participants with major depressive disorder (MDD), who were identified as partial responders to an adequate course…
- Trial name
- NCT00840034
- Testing
- LY2216684
- Where
- 24 sites in United States
- Volunteers
- 227 people
- Sponsor
- Eli Lilly and Company
Alcohol Use Disorder
HORIZANT (Gabapentin Enacarbil Extended-Release Tablets) for the Treatment of Alcohol Use Disorder
The purpose of this study is to determine whether gabapentin enacarbil is effective in the treatment of problems with alcohol.
- Trial name
- NCT02252536
- Testing
- gabapentin enacarbil
- Where
- 10 sites in United States
- Volunteers
- 346 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
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