Clinical trials: Psychiatric Illness
Alcohol Dependence, Alcoholic Relapse
Efficacy and Safety of Levetiracetam in Prevention of Alcohol Relapse in Recently Detoxified Alcohol Dependent Patients
Prospective randomized double blind controlled trial in prevention of relapse in recently detoxified alcohol dependent patients with levetiracetam and placebo.
- Trial name
- Keppra-2 (NCT00758277)
- Testing
- levetiracetam (Keppra)
- Where
- 11 sites in Germany
- Volunteers
- 201 people
- Sponsor
- Charite University, Berlin, Germany
Primary Progressive Aphasia, Repetitive Transcranical Magnetic Stimulation
rTMS Treatment of Primary Progressive Aphasia
Primary Progressive Aphasia (PPA) is a neurodegenerative disease in which language function is gradually and progressively impaired.
- Trial name
- NCT04431401
- Testing
- Magstim rTMS
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Autism Spectrum Disorder With Intellectual Deficiency
Recording Stress Biomarkers in Autism Spectrum Disorders
The goal of this observational study is to learn how stress affects children and young people with autism spectrum disorder (ASD).
- Trial name
- STRESSDEFIS (NCT07535801)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universite Cote d'Azur
Cerebrovascular Disorders, Cognition Disorders
Renji Cerebral Small Vessel Disease Corhort Study
We aim to make clear the impact with the mechanisms of variant pathological injuries on the outcomes of CSVD, to find independent imaging markers and establish prediction model of it.
- Trial name
- RCCS (NCT03544801)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Cognitive Impairment, Mild, Cognitive Dysfunction
MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment
This is a randomized, double-blind, placebo-controlled, parallel group study. The use of placebo is appropriate to minimize bias related to treatment expectations of the subject, study partner, and site investigator, as well as…
- Conditions
- Cognitive Impairment, Mild, Cognitive Dysfunction, Amyloid Plaque, Neurodegenerative Disease, Hereditary
- Trial name
- NCT06177028
- Testing
- Lenalidomide 10 mg
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
IBD (Inflammatory Bowel Disease)
Efficacy of Melatonin Treatment on Sleep Quality Improvement in Inflammatory Bowel Disease Patients With Clinical Remission
Sleep disturbances are common in patients with inflammatory bowel disease (IBD) and are associated with increased disease activity and reduced quality of life.
- Trial name
- Melatonin IBD (NCT07737665)
- Testing
- Melatonin ("Circadin")
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Mahidol University
Sleep Disorder
Effects of an Osteopathic Treatment Protocol on Sleep Quality
SIngle-centre interventional single-blinded randomized controlled trial, with random assignment of the subjects in two groups (intervention and control, 1: 1 ratio) and to be carried out with volunteers that present alterations…
- Trial name
- NCT04955392
- Testing
- Osteopathic treatment protocol
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ramón Mateos Alpuente
Obstructive Sleep Apnea, Metabolic Syndrome X
Obstructive Sleep Apnea (OSA) and Metabolic Syndrome: Role of Oxidative Stress
The purpose of this study is to define the mechanism(s) through which Obstructive Sleep Apnea/Hypopnea (OSAH) promotes abnormal metabolic processes which characterize the metabolic syndrome.
- Trial name
- NCT00177892
- Testing
- sleep disruption, sleep with and without positive pressure
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Postpartum Depression (PPD)
A Mobile Application for Early Detection and Symptoms Trajectories of Postpartum Depression Using Ecological Momentary Assessment (EMA)
This pilot study will recruit 120 perinatal pregnant women and follow them up for 6 months. Both momentary and retrospective assessments of emotional well-being and psychosocial factors will be conducted on a mobile application.
- Trial name
- EMA For PND (NCT07382336)
- Testing
- Ecological momentary assessment and retrospective assessment
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Smoking Cessation
Smoking Cessation Self-Help for Dual Users of Tobacco Cigarettes and E-Cigarettes
The purpose of this study is to develop and test a series of booklets designed to assist smokers of tobacco cigarettes who are also using e-cigarettes (dual users) in quitting smoking and remaining smoke-free.
- Trial name
- NCT02416011
- Testing
- GENERIC, eTARGET
- Where
- United States
- Volunteers
- 2,896 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Schizophrenia, Cognition Disorders
The Effect of Nicotine on Arousal, Cognition and Social Cognition in Schizophrenic Patients
This study in patients with stable schizophrenia will investigate the effect of nicotine on arousal, cognitive task and social cognition after acute dose administration.
- Trial name
- NCT01186471
- Testing
- A643 (nicotine)
- Volunteers
- 32 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Autism Spectrum Disorder
EMPATIA@Lecco- Balance Rehabilitation of Autistic Children With Virtual rEality
The general objective of this project is to investigate the possible efficacy of a training based on proprioceptive and visual feedback carried out with the GRAIL (Motekforce Link) virtual reality environment on postural control…
- Trial name
- BRAVE (NCT04276571)
- Testing
- exergames with GRAIL virtual immersive reality environment
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- IRCCS Eugenio Medea
Schizophrenia, Schizoaffective Disorder
Neural Oscillations as Genetic and Functional Biomarkers in Normal and Disease States
The principle aim of the project is to analyze brain electrical activity and genetic information that will help identify the nature and cause of the disease schizophrenia.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- NCT01425671
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Schizophrenia, Schizoaffective Disorder
Remediation of Auditory Recognition in Schizophrenia With tDCS
The purpose of this study is to determine whether transcranial direct current stimulation (tDCS), when combined with different forms of computer based training, improves the ability to discriminate small differences between…
- Trial name
- NCT02869334
- Testing
- Active Transcranial direct current stimulation (tDCS), Auditory Remediation, Control computer activities
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- New York State Psychiatric Institute
Opioid Use Disorder
OUD (Opioid Use Disorder) Target Trial
In this research study the investigators will work with 80-participants with opioid use disorder who are starting treatment with the medication buprenorphine and are trying to quit using opioids.
- Trial name
- NCT06585709
- Testing
- Active repetitive Transcranial Magnetic Stimulation (rTMS), High Ventral Striatal Reactivity, Low Ventral Striatal Reactivity
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Duke University
Pregnancy Related
The Effect of Mandala Art Therapy on Pregnant Women With Abnormal OGTT
The goal of this interventional study is to learn about determine the effect of mandala art therapy on blood glucose level, mood and anxiety in pregnant women with abnormal oral glucose tolerance test (OGTT) value.
- Trial name
- NCT05705609
- Testing
- Mandala art therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Inonu University
Anxiety Disorders
Antiglucocorticoid Therapy for Cognitive Impairment in Late-life Anxiety Disorders
This study seeks to develop and test a novel, mechanistic treatment for mitigating cognitive impairment in older adults with anxiety disorders. Anxiety disorders are common, severe, and disabling in older adults.
- Trial name
- Mifepristone (NCT01333098)
- Testing
- Mifepristone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Substance Abuse, Drug Addiction
Integrating Mindfulness-Based Skills Training Into Brief Outpatient Treatment for Substance Abusing Youth
The proposed study will evaluate the clinical effectiveness of integrating mindfulness-based skills training into a standardized brief group intervention for youth (ages 16 to 24) identified as having problematic substance use.
- Trial name
- NCT00244699
- Testing
- MI Alone or Plus Mindfulness-Based Skills Training
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Addiction and Mental Health
Postpartum Depression
Prenatal Yoga to Prevent Postpartum Depression
Although psychological interventions exist for the prevention of PPD, a yoga-based intervention to prevent PPD among at-risk women utilizes a similar theoretical foundation (i.e., mindfulness), may be more acceptable to women of…
- Trial name
- PRY-D (NCT06004232)
- Testing
- Prenatal Yoga to Prevent Postpartum Depression (PRY-D) intervention, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Henry Ford Health System
Obsessive-Compulsive Disorder, Accelerated Continue Theta-burst Stimulation
Accelerated Continue Theta-burst Stimulation (acTBS)Treatment for Obsessive Compulsive Disease
The therapeutic effects of high-dose accelerated continue theta-burst stimulation (acTBS) and 1-Hz repetitive transcranial magnetic stimulation (rTMS) on obsessive-compulsive disorder (OCD) and its neural mechanism were…
- Conditions
- Obsessive-Compulsive Disorder, Accelerated Continue Theta-burst Stimulation, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging
- Trial name
- NCT05221632
- Testing
- Accelerated transcranial magnetic stimulation with real coil, Transcranial magnetic stimulation with real coil
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
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