Clinical trials: Psychiatric Illness
Marijuana Impairment
Standardized Field Test for Marijuana Impairment II
This research responds to NHTSA's request with a proposal to increase our understanding of smoked cannabis' (CNB's) acute effects on driving-relevant cognition and simulated driving performance, the persistence of these deficits…
- Trial name
- NHTSA-II (NCT05115513)
- Testing
- Medium THC
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Yale University
Sleep, Sleep Quality
Nextsense Brain-sensing Buds Study
The purpose of this clinical trial is to explore how the presentation of sleep data impacts sleep quality, sleep-related behaviors (such as sleepiness), and sleep-related anxiety and stress.
- Conditions
- Sleep, Sleep Quality, Sleepiness, Daytime, Technology
- Trial name
- NCT06602960
- Testing
- Accurate Sleep Data Feedback, Inflated Sleep Data Feedback, Deflated Sleep Data Feedback
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NextSense, Inc.
Major Depressive Disorder
Sleep Subtypes in Adolescent Depression
The purpose of this study is to compare sleep neurophysiology and behavior in adolescents with MDD with hypersomnia (MDD-HYP) and insomnia (MDD-INS) with healthy controls (HC).
- Trial name
- NCT03742960
- Testing
- Behavioral Sleep Restriction
- Where
- Switzerland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Bern
Depressive Disorder, Major
Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia
The purpose of this research is to learn more about a new treatment for individuals with Major Depressive Disorder (MDD) with heightened symptoms of anhedonia (i.e. loss of pleasure or interest in activities).
- Trial name
- NCT06982820
- Testing
- Prism Training
- Where
- 3 sites in United States, Israel
- Volunteers
- 170 people
- Sponsor
- GrayMatters Health Ltd.
Disorders of Consciousness Due to Severe Brain Injury, Minimally Conscious State
Assessment of Consciousness With CRS-R and SECONDs
Accurately determining the level of consciousness in patients with severe brain injury is essential for treatment planning, prognosis, and ethical decision-making.
- Conditions
- Disorders of Consciousness Due to Severe Brain Injury, Minimally Conscious State, Unresponsive Wakefulness Syndrome
- Trial name
- AssessConsc (NCT07456020)
- Testing
- Simplified Evaluation of CONsciousness Disorders (SECONDs), Coma Recovery Scale-Revised (CRS-R)
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Opioid-use Disorder, Tobacco Use Disorder
Adjunctive Transcranial Stimulation to Reduce Impulsivity in Opiate Use Disorder
The goal of this study is to examine the effect of four sessions of theta burst stimulation (TBS) versus sham TMS on attentional bias for smoking and opioid cues versus neutral stimuli in a population of patients with tobacco use…
- Trial name
- NCT05049460
- Testing
- Theta Burst Stimulation
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Gopalkumar Rakesh
Psychiatric Disorder
Using Pharmacogenetics to Identify Patients With Polypharmacy at Risk of Medication Adverse Effects
The Researchers are trying to learn more about how individuals break down and process medications based on their genes. The Researchers want to find out whether subjects will have fewer side effects if they take different…
- Trial name
- NCT03748355
- Testing
- Pharmacogentic Analysis
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Intensive Care Patients
The Effect of Passive Music Therapy and Foot Massage
Patients hospitalized in tertiary intensive care units are connected to mechanical ventilators due to multiorgan failure, chronic diseases, respiratory failure, etc.
- Trial name
- NCT06078826
- Testing
- passive music therapy, foot massage
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- TC Erciyes University
Depression, Unipolar
Pulsed Electro Magnetic Fields (PEMF) in Depression
PEMF (Pulsed Electro Magnetic Fields) therapy has been used to stimulate bone repair in non-union since the 1970s. This is an accepted use, which has been approved by the Food and Drug Administration in the US.
- Trial name
- PEMF (NCT03556735)
- Testing
- Treatment with PEMF equipment
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- University of Southern Denmark
Attention Deficit Hyperactivity Disorder
Psychometric Validation of the Competitive Attention Test
This project aims at validating a new neuropsychological test to measure voluntary and involuntary attention for clinical use to diagnose attentional deficits.
- Trial name
- CAT (NCT03942835)
- Testing
- experience 1 : Competitive attention test in healthy participants, experience 2 : Competitive attention test in patients with ADHD with no treatment, experience 3 :Competitive attention test in patients with ADHD with psychostimulant treatment
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Bipolar Depression
RU-486 in the Treatment of Bipolar Depression
Bipolar disorder is a chronic and recurrent illness which involves episodes of mania and depression. It is believed that disturbance of the stress hormone system (the hypothalamic-pituitary-adrenal or HPA axis) may cause thinking…
- Trial name
- NCT00359125
- Testing
- mifepristone (RU-486)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
PTSD, Acupuncture
Acupuncture for Post-Traumatic Stress in Combat Veterans
The objective of this study is to determine if acupuncture is an effective treatment option for treating combat Veterans with PTSD.
- Conditions
- PTSD, Acupuncture, Combat
- Trial name
- NCT02871076
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Southern California Institute for Research and Education
Mild Cognitive Impairment (MCI), Older People
Digital Health and Exercise for Autonomous Longevity Program
Digital HEAL (Health and Exercise for Autonomous Longevity) is a multicomponent training program (combining concurrent training with cognitive stimulation) designed to promote physical fitness and cognitive function in older…
- Trial name
- DigitalHEAL (NCT06722976)
- Testing
- Multicomponent exercise programs
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Beira Interior
Postoperative Delirium
Pilot and Feasibility Study of a Mirrors Intervention for Reducing Delirium in Older Cardiac Surgical Patients
This pilot cluster-randomised controlled trial aims to determine whether the use of bedside mirrors, as a clearly defined part of patients' postsurgical ICU care, can reduce delirium and improve outcomes in the older cardiac…
- Trial name
- NCT01599689
- Testing
- Mirrors Intervention
- Where
- United Kingdom
- Volunteers
- 223 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Gestational Diabetes Mellitus in Childbirth, Neurodevelopmental Disorders
Early Biomarkers of Neurodevelopment in Offspring of Diabetic Mothers
The prospective multicenter study GD-Brain provides a better knowledge on the basis of neurological impairment in children born to mothers with gestational diabetes (GDM).
- Trial name
- GD-BRAIN (NCT03032991)
- Where
- Spain
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Decision Making, Bipolar Disorder
Cognitive De-Biasing and the Assessment of Pediatric Bipolar Disorder
The primary aim is to test the efficacy of a new intervention to improve clinical judgment. The investigators focus on the assessment of pediatric bipolar disorder (PBD), a controversial diagnosis with frequent diagnostic errors…
- Trial name
- NCT01799291
- Testing
- Decision Making Tutorial
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorders
Neural and Behavioral Effects of Oxytocin in Autism Spectrum Disorders
The current trial aims to explore the neural and behavioral effects of oxytocin in autism spectrum disorders (ASD). Oxytocin is a nonapeptide produced by the paraventricular and supraoptic nuclei of the hypothalamus and is known…
- Trial name
- NCT02940574
- Testing
- Syntocinon (Oxytocin)
- Volunteers
- 40 people
- Sponsor
- KU Leuven
Alzheimer's Disease, Early Onset, Logopenic Progressive Aphasia
Tau Imaging in Young Onset Dementia
The central goal of this study is to determine and compare the similarities and differences in regional brain uptake of [18F]T807 in patients with typical Alzheimer's Disease (AD), Posterior Cortical Atrophy (PCA), and Logopenic…
- Conditions
- Alzheimer's Disease, Early Onset, Logopenic Progressive Aphasia, Posterior Cortical Atrophy (PCA)
- Trial name
- NCT02289118
- Testing
- [18F]-T807 imaging tracer
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pennsylvania
Endometriosis
Endometriosis Pelvic Pain Interdisciplinary Cohort Data Registry
The purpose of this data registry is to prospectively collect data from patients referred to an interdisciplinary clinic for pelvic pain and endometriosis to investigate long-term patient outcomes, prognosis, predictors, causes…
- Trial name
- EPPIC (NCT02911090)
- Testing
- Data Registry
- Where
- Canada
- Volunteers
- 5,000 people
- Sponsor
- BC Women's Hospital & Health Centre
Premature Birth, Asthma in Children
Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age
Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental…
- Conditions
- Premature Birth, Asthma in Children, Sleep-Disordered Breathing, Neurodevelopmental Disorders
- Trial name
- NCT05336890
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
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