Clinical trials: Psychiatric Illness
Major Depressive Disorder
Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents
To evaluate the safety and efficacy of daily, active Neurostar® TMS (when compared with sham treatment) in adolescents meeting criteria for Major Depressive Disorder (MDD).
- Trial name
- NCT02586688
- Testing
- Active NeuroStar® Transcranial Magnetic Stimulation (TMS)
- Where
- 13 sites in United States
- Volunteers
- 112 people
- Sponsor
- Neuronetics
Bipolar Disorder, Mania
Treatment of Bipolar Mania in Older Adults
This study will compare the benefits and side effects of lithium and divalproex in the treatment of older adults with bipolar mania.
- Trial name
- GERI-BD (NCT00254488)
- Testing
- Lithium (LI), Divalproex (DV)
- Where
- 8 sites in United States, Canada
- Volunteers
- 224 people
- Sponsor
- Weill Medical College of Cornell University
Insomnia
Assessing the Feasibility of Web-based Insomnia Treatment Among Prostate Cancer Survivors
This pilot study will recruit Black/African American prostate cancer survivors into a clinical trial and will randomize each person to 1 of 2 possible treatments - an internet-based treatment for insomnia called Sleep Healthy…
- Trial name
- SIESTA-P (NCT07128927)
- Testing
- Sleep Healthy Using the Internet (SHUTi), Patient education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Georgetown University
Intellectual Disability
Development and Validation of the Observatory Battery of Common Eye Disorders for Adults With Intellectual Disability
Background: Around 15% of the global population has some form of disability. Rights to obtain proper health care is an emphasis in the United Nationals Convention on the Right of People with Disability.
- Trial name
- NCT06737627
- Testing
- no intervention
- Where
- 2 sites in Taiwan
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Anxiety, Depression
Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)
Depression and anxiety disorders rank in the top ten causes of years lived with disability. Less than 50% of patients experiencing long-lasting improvements to current gold-standard treatments.
- Trial name
- AAC-BeT (NCT04426461)
- Testing
- Behavioral Activation, Exposure-based therapy, Supportive therapy
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Erectile Dysfunction
Study to Assess the Efficacy and Safety of SK3530 on Erectile Dysfunction in Patients With Diabetes Mellitus
The purpose of this study is to evaluate the efficacy and safety of SK3530 on erectile dysfunction in Patients with Diabetes Mellitus.
- Trial name
- NCT00705861
- Testing
- SK3530
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- SK Chemicals Co., Ltd.
Nicotine Addiction
Acute and Chronic Nicotine Modulation of Reinforcement Learning
The purpose of this study is to use functional magnetic resonance imaging (fMRI) to investigate the acute and chronic effects of nicotine on motivational behavior and prediction error-related neural activation.
- Trial name
- NicLearning (NCT01830842)
- Testing
- Nicotine polacrilex, satiety, abstinence
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Duke University
Alcohol Dependence
Contingency Management for Chronic Recidivist Alcohol-Dependent Patients
The purpose of this study is to evaluate the efficacy of prize contingency management (CM) in reducing in-patient detoxification services for chronic recidivist alcohol-dependent patients.
- Trial name
- NCT00408161
- Testing
- Contingency Management, standard case management treatment
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- UConn Health
Adolescent Behaviour, Family Functioning
Multidimensional Treatment Foster Care for Adolescents
The purpose of the study is to examine the effects of Multidimensional Treatment Foster Care compared to treatment as usual (TAU) for adolescents in Denmark in need of out-of-home placement.
- Trial name
- NCT01726361
- Testing
- Multidimensional Treatment Foster Care, Treatment as usual
- Where
- Denmark
- Sponsor
- VIVE - The Danish Center for Social Science Research
Dementia
Adverse Drug Reactions in Older Subjects
Objective: To identify risk factors for the occurrence of adverse drug reactions (ADRs) based on geriatric evaluation. Design: Longitudinal prospective study from May 2010 to November 2011.
- Trial name
- RiskofADR (NCT03623542)
- Where
- France
- Volunteers
- 293 people
- Sponsor
- CHU de Reims
Anxiety
Comorbidity Between Balance and Childhood Anxiety
Previous studies report frequent comorbidity of anxiety and sensory-motor imbalance in adults (Sklare et al., 2001). Only a few studies tested the comorbidity in children.
- Trial name
- NCT00599742
- Testing
- Balance training, Motor training
- Where
- 2 sites in Israel
- Volunteers
- 64 people
- Sponsor
- Lev-Hasharon Mental Healtlh Center
Seasonal Affective Disorder (SAD)
Virtual Reality Digital Therapeutics for Seasonal Affective Disorder
Seasonal Affective Disorder (SAD) is commonly treated with bright light therapy. Virtual reality (VR) is an immersive computer-generated environment, which has been used to treat mental health difficulties, such as depression…
- Trial name
- VR-SAD (NCT07161570)
- Testing
- Virtual Reality (VR) Intervention, Light Box (LB) intervention
- Volunteers
- 60 people
- Sponsor
- Anglia Ruskin University
HIV Infections
A Test of Behavioral Intervention for Women at High Risk for HIV Infection
The purpose of this study is to find out if it is possible to conduct a group counseling program for women at risk for HIV infection. Women have been the fastest-growing group with new AIDS diagnoses.
- Trial name
- NCT00006440
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Low Back Pain, Stress
Effects of Global Postural Reeducation on Psychophysical Wellbeing in Housewives With Chronic Non-specific LBP.
This study aims to explore the multidimensional impact of Global postural reeducation in a population that is not only physically overburdened but also psychologically strained due to the demands of domestic life.
- Conditions
- Low Back Pain, Stress, Sleep Quality
- Trial name
- NCT07203950
- Testing
- global postural reeducation with conventional therapy, conventional therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Major Depressive Disorder, Bipolar Disorder, Mixed
Chinese Longitudinal and Systematic Study of Bioplar Disorder
Affective disorders (mainly including major depressive disorder and bipolar disorder) are common, chronic and highly disabling mental disorders, which lack of objective biological markers.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Mixed, Affective; Disorder, Organic
- Trial name
- CLASS-BD (NCT05480150)
- Testing
- Escitalopram Oxalate Tablets, Quetiapine Fumarate Tablets, Lurasidone
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Mild Cognitive Impairment, Frailty
Cognitive Frailty in Older Adults: The Role of Technology in Physical Activity Enhancement
This study intends to determine if smart watches and mobile phone application prompts can complement physical activity as a preventive intervention by motivating participants to exercise, so as to improve their physical and…
- Trial name
- NCT04692974
- Testing
- Mobile phone application and smart watch
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Bipolar Disorder
Seroquel in Acute Mania: Study to Investigate if Valproate Add-On Therapy is Superior to Quetiapine Monotherapy in Acutely Manic Patients
The primary purpose is to investigate whether the addition of sodium valproate will be superior to treatment with quetiapine (Seroquel) given as monotherapy for an additional 14 days in non-responding patients after a 14 day…
- Trial name
- NCT00139074
- Testing
- Quetiapine fumarate, sodium valproate
- Where
- 7 sites in Denmark
- Volunteers
- 17 people
- Sponsor
- AstraZeneca
Mental Health Disorder, Depression
Mobile Phone Based Intervention to Protect Mental Health in Healthcare Workers at Frontline Against COVID19
This study aims at evaluating the effectiveness of a mobile phone based intervention to prevent and manage mental health problems in healthcare workers at the frontline against COVID-19 in Spain.
- Conditions
- Mental Health Disorder, Depression, Posttraumatic Stress Disorder, Burnout
- Trial name
- PsyCovid_App (NCT04393818)
- Testing
- Intervention App
- Where
- Spain
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Chronic Insomnia
Effectiveness and Cost-effectiveness of iCBT-I in Clinical Settings
The proposed parallel-group randomized controlled trial add-on superiority of the iCBT-I program with CAU as a control condition will let us investigate the effectiveness and cost-effectiveness of iCBT-I.
- Trial name
- NCT04300218
- Testing
- internet-delivered cognitive-behavioral therapy for insomnia (iCBT-I), Care as usual (CAU)
- Where
- 3 sites in Russia
- Volunteers
- 107 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Anxiety Disorders, Depressive Disorders
Efficacy of a Transdiagnostic Group Treatment for Emotional Disorders Applied in Blended Format: a Controlled Study.
This study will consist in a randomized controlled clinical trial (RCT) to test the efficacy of a blended group transversal protocol (BLGr-TP) compared to a face-to-face group transversal protocol (FFGr-TP).
- Trial name
- NCT05569018
- Testing
- Blended group transversal protocol (BLGr-TP), Face-to-face group transversal protocol (FFGr-TP)
- Where
- Spain
- Volunteers
- 144 people
- Sponsor
- Universitat Jaume I
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