Clinical trials: Psychiatric Illness
Depression
Step Away From Depression - Evaluation of a Pedometer Intervention With Inpatients With Major Depression
The purpose of this study is to determine if the use of pedometers can help depressive inpatients in psychiatric clinics to increase their level of physical activity.
- Trial name
- SAD (NCT02850341)
- Testing
- Pedometer
- Where
- 9 sites in Austria, Germany
- Volunteers
- 292 people
- Sponsor
- Charite University, Berlin, Germany
Pathology
Different Clinicopathological Features of Non-Elderly Sigmoid Volvulus Patients
Sigmoid volvulus is frequently seen in male patients over 60 years old. In the sigmoid volvulus <60 age groups, the male/female ratio is close to each other.
- Trial name
- NCT04360525
- Testing
- Reasons
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Huntington's Disease
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease
HDClarity will seek at least 2500 research participants at different stages of Huntington's disease (HD). The primary objective is to collect a high quality CSF sample for evaluation of biomarkers and pathways that will enable…
- Trial name
- HDClarity (NCT02855476)
- Where
- 40 sites in United States, Canada and 8 more
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University College, London
Treatment Resistant Depression (TRD)
Ketamine Biomarker Validation
An EEG-based biomarker will be developed for the effects of ketamine infusion in patients with Depression. The effects of ketamine infusion on Depression symptoms and EEG signals will be analyzed.
- Trial name
- NCT07307768
- Testing
- Ketamine (0.25 mg/kg), Ketamine (0.5 mg/kg), Ketamine (0.75 mg/kg)
- Where
- United States
- Sponsor
- Soterix Medical
Healthy Volunteer
Challenging the Endocannabinoid System in Sleep Restricted Healthy Volunteers to Modulate Physiological Arousal (CANISLEEP) Study
The goal of this study is to learn about the body's response to cannabis based products in sleep deprived people who are currently experiencing anxiety but are otherwise healthy.
- Trial name
- CANISLEEP (NCT07656350)
- Testing
- THC, CBD, THC + CBD
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King's College London
Migraine, Sleep Disturbance
The Effect of Bright Light Therapy on Migraine With Sleep Disturbance
Migraine is a common disabling disorder and its substantial burden is associated with considerable negative impact on quality of life.
- Trial name
- NCT04890691
- Testing
- Feel Bright Light
- Volunteers
- 60 people
- Sponsor
- Hungkuang University
Stress, Anxiety
Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer
The goal of this study is to find the best way to help participants and families manage the stress of facing a serious illness and be better able to "bounce back" or be resilient after a difficult situation.
- Trial name
- NCT06038318
- Testing
- PRISM Program Video Coach, PRISM Program Text Coach, mPRISM Program App
- Where
- 2 sites in United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Restless Legs Syndrome
Clinical Evaluation of Ropinirole CR-RLS ( SK&F101468)Tablets in Restless Legs Syndrome
This study was designed to evaluate the safety, pharmacokinetic profile and efficacy in Restless Legs Syndrome patients.
- Trial name
- NCT00530790
- Testing
- ropinirole controlled release (CR)-RLS
- Where
- 11 sites in Japan
- Volunteers
- 35 people
- Sponsor
- GlaxoSmithKline
Major Depressive Disorder
Rapid Antidepressant Effects of Leucine
This randomized double-blind placebo-controlled crossover study seeks to evaluate the antidepressant effect of L-leucine, an essential amino acid, in patients with Major Depressive Disorder (MDD).
- Trial name
- NCT03079297
- Testing
- L-Leucine, Maltodextrin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Texas Southwestern Medical Center
Nursing, Hemodialysis Patient
THE EFFECTS OF CIRCADIAN RHYTHM-BASED PROGRESSIVE RELAXATION EXERCISES IN HEMODIALYSIS PATIENTS
The aim of this study is to determine the effect of Progressive Relaxation Exercise (PGE) applied according to the circadian rhythms of hemodialysis (HD) patients on symptom management, sleep quality, comfort and mental…
- Conditions
- Nursing, Hemodialysis Patient, Circadian Rhythm, Relaxation Exercise
- Trial name
- NCT07499297
- Testing
- Progressive Relaxation Exercises
- Volunteers
- 75 people
- Sponsor
- Karamanoğlu Mehmetbey University
Chronic Pain, Cancer
Cancer Chronic Pain Predicted by Emotional and Cognitive Status
The aim of this study is to investigate the predictive dimension of cognitive-emotional status of cancer patients on the chronic pain development 6 months after different cancer treatment protocol (surgery, chemotherapy…
- Trial name
- CanoPEe (NCT02777697)
- Testing
- chronic pain
- Where
- France
- Volunteers
- 89 people
- Sponsor
- University Hospital, Clermont-Ferrand
Sleep Disturbance, Mental Health Wellness 1
Effects of Health and Wellness App on Employee Productivity
The purpose of this study is to test the effects of using the Calm app + coaching concierge (one 20-min session) and/or Calm Coaching for sleep program on sleep, mental health, and work productivity outcomes in employees.
- Trial name
- NCT05120310
- Testing
- The Calm App
- Where
- United States
- Volunteers
- 1,029 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Depression, Anxiety
Feasibility and Acceptability of W-GenZD vs CBT-light Teletherapy for Adolescents Seeking Mental Health Services
The primary aim of this study is to determine the feasibility and acceptability of the W-GenZD mobile application among a group of adolescents and who have screened and triaged into low-intensity treatment within the Children's…
- Trial name
- NCT05372913
- Testing
- Woebot for Adolescents (W-GenZD) Mobile Application, CBT-Lite Teletherapy Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Woebot Health
Alzheimer Disease
Study of Xaliproden (SR57746A) in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type
The purpose of this study is to assess xaliproden's potential capacity of slowing the deterioration of cognitive and global functions in patients with mild to moderate Alzheimer's disease.
- Trial name
- NCT00104013
- Testing
- xaliproden (SR57746A)
- Where
- 41 sites in United States, Australia and 8 more
- Volunteers
- 1,455 people
- Sponsor
- Sanofi
SARS-CoV-2, Post-stroke Depression
Depression, Anxiety and SARS-CoV-2 (Covid-19) Phobia in Post-stroke Patients
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has begun, first in Wuhan, China, and then became a pandemic. The first SARS-CoV-2 case in Turkey was reported on March 11, 2020.
- Conditions
- SARS-CoV-2, Post-stroke Depression, Anxiety and Fear
- Trial name
- NCT04560413
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Major Depression
Treatment-Resistant Depression, Hippocampus Atrophy and Serotonin Genetic Polymorphism
Reduction of volume of the hippocampus has been associated with major depression in many studies. It has been suggested that antidepressants may protect against hippocampus volume loss in humans associated with multiple episodes…
- Trial name
- NCT00704860
- Testing
- Open label pharmacotherapy
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Depressive Disorder, Pregnancy
EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy
The purpose of this study is to assess the effectiveness of the EnBrace HR prenatal supplement in preventing depression in women with a history of depression who have decided to stop taking antidepressants during their pregnancy…
- Trial name
- NCT02676882
- Testing
- EnBrace HR
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Addressing Disparities in Autism Spectrum Disorder Diagnosis Using a Direct-to-home Telemedicine Tool
The investigators propose to evaluate the use of a telemedicine tool, the TELE-ASD-PEDS (TAP), that is designed to assess for autism spectrum disorder (ASD) symptoms in toddlers.
- Trial name
- NCT05047224
- Testing
- Tele-assessment + in-person assessment, Tele-assessment only
- Where
- United States
- Volunteers
- 664 people
- Sponsor
- Vanderbilt University Medical Center
Major Depressive Disorder
Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes
Background: Repetitive transcranial magnetic stimulation (rTMS) is a treatment for depression. It stimulates the brain. Researchers want to see if using magnetic resonance imaging (MRI) scans helps locate the best area for rTMS…
- Trial name
- NCT03289923
- Testing
- Active TMS + Cognitive therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- National Institute of Mental Health (NIMH)
Mental Disorder, Bipolar Disorder
A Descriptive Study on Patients With Bipolar Disorder in Rwanda
The aim is to provide a comprehensive assessment regarding the service provision and the accessibility to intensive mental health care in Rwanda
- Trial name
- NCT04674059
- Testing
- patient survey
- Volunteers
- 400 people
- Sponsor
- University of Aarhus
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