Clinical trials: Psychiatric Illness
Alcohol Use Disorder
Cognitive Enhancement Through Computerized Training
Alcohol use disorder is characterized by widespread neurocognitive impairments, however despite substantial advances in the intervention and treatment of alcohol use disorders, exceptionally few studies have been directed to…
- Trial name
- NCT04244032
- Testing
- Working Memory Training, Inhibitory Control Training, Bias Modification Training
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Florida
Obsessive-Compulsive Disorder, Accelerated Continue Theta-burst Stimulation
Accelerated Continue Theta-burst Stimulation (acTBS)Treatment for Obsessive Compulsive Disease
The therapeutic effects of high-dose accelerated continue theta-burst stimulation (acTBS) and 1-Hz repetitive transcranial magnetic stimulation (rTMS) on obsessive-compulsive disorder (OCD) and its neural mechanism were…
- Conditions
- Obsessive-Compulsive Disorder, Accelerated Continue Theta-burst Stimulation, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging
- Trial name
- NCT05221632
- Testing
- Accelerated transcranial magnetic stimulation with real coil, Transcranial magnetic stimulation with real coil
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Eating Disorders
Effects of Cognitive and Emotional Functioning on Treatment Outcomes
The investigators are interested about the degree to which individuals can persist with individualized treatment goals when their cues (external such as food, or internal such as anxiety) are high for impulsive/maladaptive…
- Trial name
- CEO (NCT03050632)
- Testing
- N-back, White Bear Task
- Where
- United States
- Sponsor
- Boston University Charles River Campus
Cognitive Impairment, Mood Disorders
Performances of a Brief Assessment Tool for the Early Diagnosis of Geriatric Syndromes by Primary Care Physicians
The AGE (Active Geriatric Evaluation) aims to develop a brief assessment tool adapted to the primary care setting.
- Conditions
- Cognitive Impairment, Mood Disorders, Urinary Incontinence, Malnutrition
- Trial name
- NCT01816087
- Testing
- brief geriatric assessment
- Where
- Switzerland
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Chronic Pain, Mental Disorder
Early Detection of Mental Disorders in Adolescents With Chronic Pain: Creation of a Screening Tool for Use by the General Practitioner
This research aims to create a tool for detection of mental health disorders in adolescents with chronic pain. The first part is testing a screening questionnaire and comparing in with existing questionnaires.
- Trial name
- REPERADO (NCT04467229)
- Testing
- Focus group
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cocaine Dependence, Depressive Symptoms
Clinical Efficacy of Sertraline Augmented With Gabapentin in Depressed, Recently Abstinent Cocaine-dependent Humans
To examine the clinical efficacy of sertraline (200 mg/day) alone or sertraline in combination with gabapentin. The purpose of this study is to examine whether the antidepressant sertraline alone or combined with gabapentin…
- Trial name
- NCT00654953
- Testing
- sertraline, gabapentin
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Arkansas
Coronary Artery Disease, Coronary Artery Ectasia
Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method
This study evaluates the effects of emotional status on coronary flow in patients undergoing elective coronary angiography. Patients whom undergoing elective coronary angiography will fulfill the Beck Anxiety Inventory, Beck…
- Conditions
- Coronary Artery Disease, Coronary Artery Ectasia, Slow-Flow Phenomenon, Endothelial Dysfunction
- Trial name
- STRAIN-TIMI (NCT02831153)
- Testing
- coronary angiography
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Ertan YETKIN
Depression Disorders, Affective Disorders
Prevention of Mental Disorders Through Self-efficacy Interventions
Low self-efficacy is a transdiagnostic risk factor for several mental disorders. Self-efficacy refers to one's belief that one is capable of performing a behavior necessary to successfully complete a task or achieve a goal.
- Conditions
- Depression Disorders, Affective Disorders, Prevention, Substance Use Disorders
- Trial name
- SELFTIE (NCT06738953)
- Testing
- Cognitive-Behavioral Intervention to increase Self Efficacy
- Where
- Germany
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Health and Medical University Potsdam
Drug Addiction
Survey of Buprenorphine Use Among "Out of Care" Population in France (P04933)(COMPLETED)
This study was a survey of drug users who obtain buprenorphine from the black market and have used buprenorphine during the last month.
- Trial name
- NCT00756353
- Volunteers
- 600 people
- Sponsor
- Indivior Inc.
Major Depressive Disorder
Mechanisms of Antidepressant Non-Response in Late-Life Depression
This project seeks to elucidate the mechanisms by which antidepressant medications have limited efficacy in Late Life Depression (LLD) in order to develop new treatment interventions for this prevalent and disabling illness.
- Trial name
- NCT01931202
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- New York State Psychiatric Institute
Heart Failure, Delirium Confusional State
Delirium and Heart Failure
Biomarkers such as Systemic Immune-Inflammation Index (SII) and TG/Glucose Ratio (TyG) have shown promise in predicting delirium, reflecting the roles of inflammation and metabolic disturbances in its pathophysiology.
- Trial name
- NCT07302737
- Testing
- Comprehensive Geriatric Assessment, the Confusion Assessment Method (CAM test) or CAM-ICU, Delirium Rating Scale - Revised-98
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypoactive Delirium, Hyperactive Delirium
Delirium Prevention in Patients From the Intensive Care Unit (DELA)
"To determine the efficacy of program of prevention of delirium in critically ill patients from the intensive care units of Bucaramanga and Floridablanca.
- Conditions
- Hypoactive Delirium, Hyperactive Delirium, Delirium of Mixed Origin
- Trial name
- DELA (NCT03215745)
- Testing
- Delirium prevention program
- Where
- Colombia
- Volunteers
- 200 people
- Sponsor
- Universidad de Santander
Psychological Distress, Stress, Psychological
ASD (Autism Spectrum Disorder) Telehealth for Distress Related to COVID-19
The purpose of this study is to evaluate the feasibility, acceptability and effectiveness of a brief, telehealth intervention (the Emotional Support Plan), intended to support autistic adults to cope with their negative emotions…
- Conditions
- Psychological Distress, Stress, Psychological, Autism Spectrum Disorder
- Trial name
- NCT04460677
- Testing
- Emotional Support Plan, Daily Monitoring
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Rutgers, The State University of New Jersey
Cystoscopy
Effects of Music Therapy on Procedural Pain, Anxiety and Comfort Level During Cystoscopy
Aims and objectives: This study aimed to determine the effect of music therapy on procedural pain intensity and anxiety and comfort levels in patients during cystoscopy.
- Trial name
- NCT04413175
- Testing
- music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ordu University
Posttraumatic Stress Disorder (PTSD), Specific Phobia
Intervention for Anxiety After Falls
The purpose of this study is to determine whether a brief intervention for disabling anxiety is practical to conduct and beneficial for older adults injured by falls.
- Conditions
- Posttraumatic Stress Disorder (PTSD), Specific Phobia, Anxiety
- Trial name
- NCT01268657
- Testing
- Education, Relaxation Training, Cognitive Restructuring
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Weill Medical College of Cornell University
PTSD, Depression
National Guard Outreach and Linkage to Treatment
This project will add an evaluation/research component to an existing peer outreach program, now implemented for over 1100 soldiers in the Michigan Army National Guard. Preliminary work will be completed in three areas.
- Conditions
- PTSD, Depression, Reintegration, Veterans Health
- Trial name
- NCT01020981
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Eye Movement Desensitization and Reprocessing Intervention, Blood Pressure
The Effect of Eye Movement Desensitization and Reprocessing Intervention in Hypertension Patient.
Eye Movement Desensitization and Reprocessing intervention may improve anxiety, depression, systolic blood pressure and heart rate variability in patients with hypertension.
- Conditions
- Eye Movement Desensitization and Reprocessing Intervention, Blood Pressure, Heart Rate Variability, Anxiety
- Trial name
- EMDR (NCT05836181)
- Testing
- Eye Movement Desensitization and Reprocessing
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Miao-Yi Chen
Alzheimer's Disease, Dementias
Cerebrospinal Fluid (CSF) Biomarkers Alzheimer's Disease (AD) and Non-AD Dementias
To establish a cutoff value using a ratio of CSF tau to Aβ42 (tau/Aβ42) for distinguishing patients wth mild to moderate Alzheimer's disease (AD) from health elderly control subjects.
- Trial name
- NCT01730430
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Pregnancy Related
Different Anesthesia Methods on Development of Postnatal Depression After Cesarean Delivery
Childbirth is one of the most painful experiences for a woman. Labor and period of pregnancy is associated with an increased risk of psychiatric disorders for a woman.
- Trial name
- NCT04565730
- Testing
- Grup I= General anesthesia group, Grup II= Spinal anesthesia group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Medipol University
Schizophrenia, Epilepsy
A Drug Interaction Study of Valproic Acid and Single-dose Paliperidone Extended-Release (ER) in Healthy Men
The purpose of this study is to evaluate the effect of valproic acid (VPA) on the pharmacokinetics (blood levels) of a single oral dose of an extended-release formulation of paliperidone in healthy male volunteers.
- Trial name
- NCT01060228
- Testing
- paliperidone ER, divalproex sodium ER
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
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