Clinical trials: Psychologic Stress
Psychological Stress, Depressive Symptoms
Effectiveness of Medicorp HO Preparatory Course
After completion of 5 years of medical school training, the next step of becoming a House Officer is said to be associated with high levels of stress.
- Conditions
- Psychological Stress, Depressive Symptoms, Anxiety State, Motivation
- Trial name
- NCT03510195
- Testing
- MEDICORP HO PREPARATORY MODULE
- Where
- Malaysia
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Grief, Post Traumatic Stress Disorder
Building and Sustaining Interventions for Children: Task-sharing Mental Health Care in Low-resource Settings
The BASIC study will take place in Kanduyi/Bungoma South Sub-County, in western Kenya, and focuses on children orphaned by one or two parents.
- Conditions
- Grief, Post Traumatic Stress Disorder, Depression
- Trial name
- BASIC (NCT03243396)
- Testing
- Trauma-Focused Cognitive Behavioral Therapy
- Where
- Kenya
- Volunteers
- 956 people
- Sponsor
- Duke University
Perimenopausal Disorder, Stress, Emotional
The Menopause Transition: Estrogen Variability, Stress Reactivity and Mood
Women in the menopause transition ('perimenopause') are exposed to extreme hormone variability, tend to experience a unique set of severe stressors (e.g., divorce, death of loved ones), and are also at substantially elevated risk…
- Trial name
- Changes (NCT03003949)
- Testing
- Estradiol Patch, 0.1 Mg/24 Hours Weekly Transdermal Film, Extended Release, Progesterone Capsule
- Where
- 2 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Post Traumatic Stress Disorder, Depression
Does an Occupational Therapy Program Enhance Mental Health Outcomes for Veterans Who Scuba Dive
The purpose of the study is to investigate whether an occupational therapy program could enhance mental health outcomes for veterans who SCUBA dive.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety, Stress, Psychological
- Trial name
- NCT03928392
- Testing
- SCUBA with Occupational Therapy (OT), Self-Contained Underwater Breathing Apparatus (SCUBA) without OT
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Loma Linda University
Anxiety, Depressive Symptoms
StriveWeekly Online Mental Health Trial Post-pandemic
With the COVID-19 pandemic completely altering the landscape of higher education, students have been experiencing more stress than ever.
- Conditions
- Anxiety, Depressive Symptoms, Stress, Emotional
- Trial name
- NCT04927845
- Testing
- StriveWeekly
- Where
- United States
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- Harvard University
Cancer, Survivorship
A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers
The purpose of this pilot study is to examine the feasibility and acceptability of a brief psychotherapy intervention to improve psychosocial coping and maintain couple relationships among young adults (aged 25-39) with cancer…
- Conditions
- Cancer, Survivorship, Caregiver Burden, Psychological Distress
- Trial name
- YAD (NCT06172907)
- Testing
- Young Adults Coping with Cancer Together Intervention
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
HIV, Acquired Immunodeficiency Syndrome
A Unified Intervention for Young Gay and Bisexual Men's Minority Stress, Mental Health, and HIV Risk
The intent of the proposed randomized controlled trial is to test the efficacy of a principle-based, transdiagnostic cognitive behavioral therapy (CBT) intervention that addresses the pathways through which minority stress…
- Trial name
- NCT02929069
- Testing
- ESTEEM, CMHT, VCT
- Where
- 2 sites in United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Yale University
Posttraumatic Stress Disorder
IOK Treatment Study
The goals of this project are 1) to evaluate the effectiveness of a CBT treatment module addressing the mental health and functional impact of killing in the war zone, 2) to gather data on Veteran stakeholders' perceptions of…
- Trial name
- NCT01605799
- Testing
- IOK Killing Treatment, Wait list control group
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Adolescent With Early Life Stress, Resilience
Mindfulness for Resilience in Early Life
Early life stress (ELS) is associated with a number of psychiatric and medical conditions later in life, thought to be caused by subsequent disruptions in biological processes involved in regulation of stress responses.
- Trial name
- MindREaL (NCT03633903)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Loneliness, Emotional Stress
Twitter Based Social Support for Hispanic and Black Dementia Caregivers
The prevalence of dementia is higher in Hispanics and African Americans than non-Hispanic Whites. Moreover, dementia caregivers often experience loneliness as well decreased health status.
- Trial name
- Tweet-S2 (NCT03865498)
- Testing
- Twitter for Hispanic caregivers, Twitter for African American caregivers
- Where
- United States
- Volunteers
- 966 people, healthy volunteers welcome
- Sponsor
- Columbia University
Intensive Care Unit Survivors, Informal Caregivers (Family and Friends)
Improving Psychological Distress Among Critical Illness Survivors and Their Caregivers
Patients who receive life support in intensive care units commonly suffer from persistent depression, anxiety, and post-traumatic stress disorder (PTSD) symptoms after discharge.
- Trial name
- NCT01983254
- Testing
- coping skills training, education program
- Where
- 4 sites in United States
- Volunteers
- 417 people
- Sponsor
- Duke University
Dementia, Caregiver Burden
Knowledge and Interpersonal Skills to Develop Exemplary Relationships (KINDER): Pilot Study
The purpose of this study is to determine the feasibility and acceptability of delivering the KINDER intervention to family caregivers to persons living with dementia.
- Conditions
- Dementia, Caregiver Burden, Relation, Family, Elder Abuse
- Trial name
- KINDER (NCT05783102)
- Testing
- Knowledge and Interpersonal Skills to Develop Exemplary Relationships
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Major Depressive Disorder, Post Traumatic Stress Disorder
Positive Processes and Transition to Health
The R61 will be an open trial to determine if Positive Processes and Transition to Health (PATH) engages the proposed targets: unproductive processing, avoidance, and reward deficits in a sample of 45 adults who have experienced…
- Trial name
- PATH (NCT04678232)
- Testing
- Positive Processes and Transition to Health (PATH)
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Case Western Reserve University
Burden, Caregiver
Social Support and Stress Reduction for Caregivers of Young Adults With IDD
The objective of this study is to evaluate the feasibility and stress reduction impacts of a yoga and support group intervention on caregivers of individuals with intellectual and developmental disabilities.
- Trial name
- CareWell (NCT05938998)
- Testing
- Yoga; Support Group
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Psychological Stress
Stress, Sex, and the Generalization of Fear
The impact of well-known risk factors for such disorders (stress, biological sex, anxiety-related dispositions) on fear generalization will be examined.
- Trial name
- NCT03786952
- Testing
- Stress immediately before learning in males, Stress 30 minutes before learning in males, Stress immediately before learning in females
- Where
- United States
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Ohio Northern University
Stress, Professional, Stress, Psychological
Brief Mindfulness Meditation Course to Reduce Stress in Healthcare Professionals
Stress among healthcare professionals is well documented. Untreated stress can lead to anxiety, depression, substance use, and suicide.
- Trial name
- NCT03781336
- Testing
- Mindfulness-based self care
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Alzheimer Disease and Related Dementias, Dementia Alzheimers
MASC: Reducing Stress for Caregivers
Building on limitations of prior research, the investigators proposed to develop the Mindful and Self-Compassionate Care Program (MASC) to help caregivers of persons with Alzheimer Disease and Related Dementias (ADRD) manage…
- Trial name
- MASC (NCT05847153)
- Testing
- MASC
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Loneliness, Social Isolation
Engage Psychotherapy to Promote Connectedness in Caregivers
The Engage Coaching Project is a Stage 1 intervention development study. This study asks: "what behavioral strategies are needed to help socially disconnected caregivers with significant barriers to increasing connectedness?"…
- Conditions
- Loneliness, Social Isolation, Caregiver Burnout
- Trial name
- NCT04176601
- Testing
- Engage coaching
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Rochester
Pregnancy Related, Burnout, Professional
The 4th Trimester Initiative: The Impact of Parental Support on Pregnant Trainee Wellbeing
The goal of this clinical trial is to determine the impact of a parental support package for new trainee mothers which focuses on mentorship, lactation, and sleep, and access to perinatal care.
- Conditions
- Pregnancy Related, Burnout, Professional, Wellness, Psychological
- Trial name
- NCT06014892
- Testing
- Snoo smart bassinet, Willow wearable breast pump, Maven Clinic on-demand perinatal consultation
- Where
- 7 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alzheimer Disease, Dementia
Technology and Family Thriving Study
The purpose of this project is to test the impact of different forms of technology (virtual reality vs. video chat) on quality of life and family relationships in older adults who reside in senior living communities and an adult…
- Conditions
- Alzheimer Disease, Dementia, Caregiver Burnout, Quality of Life
- Trial name
- Thrive (NCT05150990)
- Testing
- Virtual Reality, Video Chat
- Where
- 27 sites in United States
- Volunteers
- 186 people
- Sponsor
- University of California, Santa Barbara