Clinical trials: Psychological Disorder
Attention Deficit Hyperactivity Disorder
Safety and Efficacy of GTS21 in Adults With Attention-deficit Hyperactivity Disorder
This study will be a randomized, double-blind, placebo-controlled crossover study to assess the effects of GTS21 (25 mg three times a day (tid), 75 mg tid, 150 mg tid) compared to placebo in non-smoking adults aged 18-55 with a…
- Trial name
- NCT00419445
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- CoMentis
Lung Cancer
Reducing Lung Cancer-Related Anxiety (RELAX)
The purpose of this research study is to compare the effects of music and different levels of device-guided breathing on anxiety and shortness of breath in lung cancer survivors.
- Trial name
- RELAX (NCT02063828)
- Testing
- Group A - Device guided breathing low dose, Group B - Device guided breathing high dose, Group C - Usual Breathing Control Group
- Where
- 11 sites in United States
- Volunteers
- 46 people
- Sponsor
- Wake Forest University Health Sciences
Cannabis, Pain
Repeated Cannabis Administration on Experimental Pain and Abuse Liability
Chronic pain is a significant public health concern in the U.S., for which prescription opioids have historically been the standard treatment. This has resulted in striking rates of opioid use disorders and fatal overdoses.
- Conditions
- Cannabis, Pain, Tolerance, Hyperalgesia
- Trial name
- NCT04576507
- Testing
- Active Cannabis
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Major Depressive Disorder
The BIomarker Guided (BIG) Study for Depression
Cognitive impairments contribute significantly to psychosocial dysfunction in major depressive disorder (MDD) and respond poorly to conventional antidepressants, yet selective treatments targeted to these impairments are lacking.
- Trial name
- NCT04181736
- Testing
- Guanfacine Tablets
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Stanford University
Depressive Disorder, Major
European Deep Brain Stimulation (DBS) Depression Study
To evaluate the effects of two different programming settings of deep brain stimulation (DBS) in the subgenual white matter (Brodmann Area 25 WM) as an adjunctive treatment for treatment resistant Major Depressive Disorder…
- Trial name
- NCT01331330
- Testing
- Deep Brain Stimulation
- Where
- 5 sites in France, Israel and 1 more
- Volunteers
- 9 people
- Sponsor
- Abbott Medical Devices
Bipolar Depression
Brexpiprazole for Bipolar Depression
The investigators will conduct an 8-week, non-randomized, open-label study of brexpiprazole in 20 persons with bipolar I or II disorder, depressed mood state.
- Trial name
- NCT03427892
- Testing
- Brexpiprazole
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Texas Southwestern Medical Center
Schizophrenia; Psychosis
Pharmacologic Modulation of Hippocampal Activity in Psychosis
The purpose of this study is to test whether administration of levetiracetam (LEV), a commonly used anti-epileptic that alters neurotransmitter release, can reduce hippocampal hyperactivity.
- Trial name
- NCT04277936
- Testing
- Levetiracetam 500 mg
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Autism Spectrum Disorder
Computer-based Social Skills Training for Autism Spectrum Disorder
The primary objective of this study is to evaluate changes in subject performance on social skills assessments after engaging in a gaze-controlled video game that leverages ABA principles of learning, in comparison to an…
- Trial name
- NCT03672344
- Testing
- Lookware TM, Lookware TM Control Module
- Where
- 11 sites in United States
- Volunteers
- 54 people
- Sponsor
- BioStream Technologies, LLC
Binge Drinking
Alcohol and Neural Cardiovascular Control in Binge Drinkers
This study evaluates the impact of evening alcohol consumption on sympathetic activity and baroreflex function in binge drinkers.
- Trial name
- NCT03567434
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Baylor University
Borderline Personality Disorder
Cognitive Reappraisal Training for Borderline Personality
Previous work by the study group convinced the study team to pursue development of focused cognitive reappraisal training as a novel approach to treatment of BPD, either as stand-alone treatment or in concert with evidence-based…
- Trial name
- BPD (NCT04967222)
- Testing
- Cognitive Reappraisal by Distancing, Control Downregulate Condition
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gender Dysphoria
Understanding Perceived Access and Receipt of Gender-affirming Treatments Among Transgender Veterans
Transgender Veterans (trans Vets) frequently experience gender dysphoria or distress related to discord between their gender identity and birth sex.
- Trial name
- NCT06615401
- Where
- United States
- Volunteers
- 986 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Postoperative Cognitive Dysfunction
Optimization of Desflurane in Elderly Patients
Various issues had been pointed out when undergoing the anesthesia for elderly patients with sevoflurane, such as delayed emergence, post-operative trouble with swallowing.
- Trial name
- NCT01700907
- Testing
- Desflurane, Sevoflurane
- Where
- Japan
- Volunteers
- 20 people
- Sponsor
- Sapporo Medical University
Marijuana Dependence
Buspirone Treatment for Marijuana Dependence
Marijuana is the most commonly used illicit drug, yet few clinical trials have evaluated pharmacotherapy treatments for marijuana dependence.
- Trial name
- NCT00875836
- Testing
- Buspirone
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Medical University of South Carolina
Narcolepsy
Safety and Efficacy Study of Armodafinil (CEP-10953) in the Treatment of Excessive Sleepiness Associated With Narcolepsy
The primary objective of this study is to determine whether treatment with Armodafinil (CEP-10953) is more effective than placebo treatment for patients with excessive sleepiness associated with narcolepsy by measuring mean sleep…
- Trial name
- NCT00078377
- Testing
- Armodafinil
- Volunteers
- 196 people
- Sponsor
- Cephalon
Mild Cognitive Impairment
NAD Therapy for Improving Memory and Brain Blood Flow in Older Adults With Mild Cognitive Impairment
This study will provide insight into whether a nutritional supplement, nicotinamide riboside (NR), improves memory and brain blood flow in older adults with low memory abilities.
- Trial name
- NCT03482167
- Testing
- Niagen®
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Delaware
PTSD
Trauma-informed Collaborative Care for Low-income African Americans With PTSD
The purpose of this study is to optimize, culturally adapt, implement, and pilot test a trauma-informed collaborative care intervention for low-income African Americans who receive care in Federally Qualified Health Centers…
- Trial name
- NCT03591107
- Testing
- PTSD Care Management (PCM), Minimally Enhanced Usual Care (MEU)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- RAND
Adolescent Well-Being, Mental Disorders, Severe
Adolescents' Well-being in Community-based Treatment Versus Residential Treatment
This is a quasi-experimental longitudinal study to compare the outcomes of youth in a Psychiatric Residential Treatment Facility (PRTF) compared to youth in the community-based Child-Focused Assertive Community Treatment Team…
- Trial name
- NCT06498427
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Outcome Referrals, Inc.
Alzheimers Disease, Dementia
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.
The purpose of this study is to assess the safety, tolerability, biomarker and cognitive efficacy of investigational products in subjects who are known to have an Alzheimer's disease-causing mutation by determining if treatment…
- Conditions
- Alzheimers Disease, Dementia, Alzheimers Disease, Familial
- Trial name
- DIAN-TU (NCT04623242)
- Testing
- Gantenerumab, Solanezumab
- Where
- 25 sites in United States, Australia and 6 more
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Major Depressive Disorder, Menopause
A Neurosteroid Intervention for Menopausal and Perimenopausal Depression
HYPOTHESIS: Pregnenolone administration will be associated with greater reduction in depressive symptom severity than placebo in women with current mMDD.
- Conditions
- Major Depressive Disorder, Menopause, Perimenopause
- Trial name
- NCT03505905
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Texas Southwestern Medical Center
Mental Illness, Shared Decision Making
Goal Elicitation, Treatment Prioritization, & Electronically-Practiced Discussion for Psychiatry
GET PrEPD-Psychiatry is a mixed-methods, developmental study to adapt a shared decision making (SDM) intervention to be specific for psychiatry decisions (Aim 1, previously completed), evaluate its feasibility and acceptability…
- Trial name
- GET-PrEPD (NCT04601194)
- Testing
- Coaching and Virtual Provider Program Practice
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Indiana University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.