Clinical trials: Psychological Disorder
Therapeutic Play, Anxiety
The Effect of Therapeutic Play Applied by Using Toy Nebulizer and Toy Mask on Child's Fear and Anxiety Level
In this study, it was aimed to examine the effect of therapeutic play applied with a toy nebulizer and toy mask before inhaler treatment on children's fear and anxiety.
- Conditions
- Therapeutic Play, Anxiety, Fear
- Trial name
- NCT05415566
- Testing
- toy nebulizer and toy mask
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ege University
Major Depressive Disorder, Healthy Participants
A Study of the Neurobiology of Depression
Previous research studies have shown that depression is associated with changes in structure and activity in different parts of the brain and that antidepressant medication can affect brain activity in different parts of the…
- Trial name
- NCT01051466
- Testing
- Duloxetine
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy
Study Evaluating Potential Interaction Between SAM-531 And Gemfibrozil When Co-Administered
The purpose of this study is to evaluate the effects of multiple doses of Gemfibrozil on the plasma concentration of a single dose of SAM-531 in healthy young adult subjects and to assess the safety and tolerability of…
- Trial name
- NCT00966966
- Testing
- SAM-531 and gemfibrozil
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Normal Physiology, Alcohol Use Disorder
Addictions Neuroclinical Assessment (ANA)
Background: Alcohol use disorder (AUD) is a major public health problem. In the U.S., 16 to 18 million adults have an AUD. Researchers want to test an assessment tool called the ANA.
- Trial name
- NCT04946851
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Stress-related Problem, Breastfeeding
Effects of Different Relaxation Interventions on Reducing Stress in Chinese Breastfeeding Mothers
This pilot study aims to find the most effective relaxation technique to help primiparous mothers who are breastfeeding their infant.
- Conditions
- Stress-related Problem, Breastfeeding, Relaxation Therapy, Psychological Stress
- Trial name
- NCT03593551
- Testing
- five relaxation treatments and one control
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College, London
Body Dysmorphic Disorder
Milk Thistle in Body Dysmorphic Disorder
The proposed study will consist of a 9 week double-blind cross-over study trial of milk thistle in 15 people (ages 18-65). The study will be divided into an initial 4 week phase, a one week wash out phase, and a second 4 week…
- Trial name
- NCT02843451
- Testing
- Milk Thistle
- Where
- United States
- Sponsor
- University of Chicago
Mental Disorders, Severe
Improving Employment Outcomes for Probationers With Mental Illnesses
Employment is a key protective factor against recidivism; however, the lack of job opportunities keeps justice-involved mentally ill individuals, especially young adults of color, unemployed and at risk for future justice…
- Trial name
- NCT04948853
- Testing
- Individual Placement Support - Supported Employment
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of North Carolina, Chapel Hill
Major Depressive Disorder
Evaluation of a Male-specific Psychotherapeutic Program for Major Depressive Disorders
This project aims to evaluate a male-specific psychotherapeutic program (MSPP) for MDD based on cognitive behavioral therapy (CBT). The primary goal is to test the superiority of the MSPP.
- Trial name
- MSPP-MDD (NCT05435222)
- Testing
- Male-specific psychotherapeutic program (MSPP), Cognitive beahvioral therapy (CBT)
- Where
- Switzerland
- Volunteers
- 244 people
- Sponsor
- Andreas Walther
Alcohol Use Disorder, HIV-infection/Aids
Development of an Intervention to Reduce Heavy Drinking and Improve HIV Care Engagement Among Fisherfolk in Uganda
Fisherfolk are a high risk population for HIV and are prioritized to receive antiretroviral treatment (ART) in Uganda, but risky alcohol use among fisherfolk is a barrier to HIV care engagement; multilevel factors influence…
- Trial name
- NCT03919695
- Testing
- Kisoboka: Behavioral and Structural Intervention, Screening and Referral
- Where
- Uganda
- Volunteers
- 160 people
- Sponsor
- San Diego State University
Stress, Psychological, Anxiety
Effectiveness of a Supervised Hospital-based Physical Exercise
To assess if physical activity is effective in reducing stress and anxiety in healthcare professionals.
- Trial name
- NCT04851795
- Testing
- supervised physical exercise sessions, unsupervised physical exercise
- Where
- 2 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Bioaraba Health Research Institute
Older Adults (50-90 Years)
Effects of Brain Stimulation During a Daytime Nap on Memory Consolidation in Older Adults
The beneficial effect of nocturnal as well as daytime sleep on memory consolidation is well-documented in young, healthy subjects.
- Trial name
- NCT01840839
- Testing
- brain stimulation
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Mild Cognitive Impairment (MCI)
Non-invasive Deep Brain Stimulation to Enhance Motor Skill Acquisition in Individuals With Mild Cognitive Impairment
The goal of this study is to investigate the impact of non-invasive deep brain stimulation on motor skill acquisition in individuals with Mild Cognitive Impairment.
- Trial name
- NCT07092839
- Testing
- transcranial electric stimulation
- Where
- 2 sites in Switzerland
- Volunteers
- 15 people
- Sponsor
- Friedhelm Hummel
Glucose Intolerance, Sleep Deprivation
Influence of Nocturnal Light Exposure on the Impairment of Glucose Tolerance Induced by Chronic Sleep Restriction
This project is designed to test for the first time whether glucose metabolism is differentially impaired by sleep restriction with and without additional exposure to artificial light at night (ALAN).
- Conditions
- Glucose Intolerance, Sleep Deprivation, Sleep
- Trial name
- NCT04868539
- Testing
- Sleep Restriction with ALAN first, then Sleep Restriction without ALAN, Sleep Restriction without ALAN first, then sleep restriction with ALAN
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cocaine-Related Disorders
Cocaine Abuse and ADHD - 10
The purpose of this study is to evaluate the safety and efficacy of buproprion in treating individuals with adult attention-deficit hyperactivity disorder (ADHD) and cocaine dependence.
- Trial name
- NCT00000275
- Testing
- Flupenthixol
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Obesity, Morbid
Clinical Efficacy of a Virtual Reality Tool for the Treatment of Obesity
The objective of the study, which is framed within European Union's H2020 project titled SOCRATES, is to assess the clinical efficacy of a Virtual Reality (VR) embodiment tool for treating obesity and to compare it to usual care…
- Trial name
- SOCRATES (NCT05094557)
- Testing
- Experimental Group 1: Body swapping VR intervention + psychoeducational video + Treatment As usual, Experimental Group 2: VR intervention without body swapping + psychoeducational video + Treatment As usual, Control Group: Psychoeducational video + Treatment As usual
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Psychological Well Being, Behavioral Management
Behavioral Management and Psychological Well-Being
The aim of present study is to evaluate whether a program of behavioral and cognitive procedures for emotional control, and assertive training, produces well-being and improvement in quality of life of healthy volunteers.
- Trial name
- NCT01823601
- Testing
- Behavioral Management Program, Seminars in Health
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Centro de Estudos em Medicina Comportamental
Insomnia, Psychosis
Implementation of Digital CBT for Insomnia in First Episode Psychosis
This study uses mixed methods to investigate the implementation of digital cognitive behavioural therapy for insomnia (Sleepio) in a first episode of psychosis service (FEP).
- Conditions
- Insomnia, Psychosis, First Episode Psychosis
- Trial name
- NCT05050201
- Testing
- Sleepio
- Where
- 2 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- NHS Greater Glasgow and Clyde
Alcohol Use Disorder, Alcoholic Liver Disease
Alcoholic Liver Disease and the Gut Microbiome
Background: Significant sex differences exist in regard to alcohol use disorder (AUD) and alcoholic liver disease (ALD). To date, no studies have examined the brain-gut-microbiome (BGM) axis (which is the relationship between the…
- Conditions
- Alcohol Use Disorder, Alcoholic Liver Disease, Microbiome
- Trial name
- NCT05007470
- Testing
- VSL #3 112.5 Capsule
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Psychological Trauma, Posttraumatic Stress Disorder PTSD
Psychometric and Patholinguistic Assessment of Psychotrauma Related to Natural Hazards in the Commune of "Le Prêcheur"
The project is to study the evolution of mental health in a little town of the French Martinique (Le Prêcheur) by using an innovative method of analysis that combines patholinguistic and psychometric indications for patients who…
- Conditions
- Psychological Trauma, Posttraumatic Stress Disorder PTSD, Mass Casualty Incidents
- Trial name
- EP3LAN (NCT04479670)
- Where
- Martinique
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Cocaine Dependence
Carbidopa/Levodopa Combined With Behavioral Therapy for the Treatment of Cocaine Dependence
Cocaine dependence is a major public health problem and the development of a treatment for this disorder is a priority. To date, treatment interventions based on positive incentive principles have shown the strongest effects for…
- Trial name
- NCT00713583
- Testing
- levodopa, Cognitive Behavioral Therapy, Contingency Management
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- The University of Texas Health Science Center, Houston